null

SMILES: CCN1CCN(CC1)c1ccc(NC(=O)COc2ccccc2)cc1Cl

InChI Key: InChIKey=SNYLXINFZFDVHF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50373832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (RAT)	BDBM50373832 (CHEMBL429780) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)COc2ccccc2)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-2-23-10-12-24(13-11-23)19-9-8-16(14-18(19)21)22-20(25)15-26-17-6-4-3-5-7-17/h3-9,14H,2,10-13,15H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M4 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50373832 (CHEMBL429780) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)COc2ccccc2)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-2-23-10-12-24(13-11-23)19-9-8-16(14-18(19)21)22-20(25)15-26-17-6-4-3-5-7-17/h3-9,14H,2,10-13,15H2,1H3,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M1 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (RAT)	BDBM50373832 (CHEMBL429780) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)COc2ccccc2)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-2-23-10-12-24(13-11-23)19-9-8-16(14-18(19)21)22-20(25)15-26-17-6-4-3-5-7-17/h3-9,14H,2,10-13,15H2,1H3,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50373832 (CHEMBL429780) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)COc2ccccc2)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-2-23-10-12-24(13-11-23)19-9-8-16(14-18(19)21)22-20(25)15-26-17-6-4-3-5-7-17/h3-9,14H,2,10-13,15H2,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M3 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50373832 (CHEMBL429780) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)COc2ccccc2)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-2-23-10-12-24(13-11-23)19-9-8-16(14-18(19)21)22-20(25)15-26-17-6-4-3-5-7-17/h3-9,14H,2,10-13,15H2,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M2 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair