BDBM50399684 CHEMBL2178944

SMILES: Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@@H]1CC[C@H](CC(O)=O)CC1

InChI Key: InChIKey=YXFNPRHZMOGREC-GASCZTMLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50399684 (CHEMBL2178944) Show SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@@H]1CC[C@H](CC(O)=O)CC1 |r,wU:17.18,20.22,(39.9,-10.55,;41.23,-9.78,;42.57,-10.55,;43.9,-9.77,;45.24,-10.54,;43.9,-8.24,;42.57,-7.47,;41.23,-8.23,;39.9,-7.46,;38.56,-8.23,;39.9,-5.92,;45.23,-7.47,;46.56,-8.24,;47.9,-7.47,;47.9,-5.92,;46.56,-5.16,;45.23,-5.93,;49.23,-5.15,;50.57,-5.92,;51.89,-5.15,;51.89,-3.61,;53.23,-2.84,;54.56,-3.61,;55.9,-2.84,;54.56,-5.15,;50.56,-2.84,;49.22,-3.61,)| Show InChI InChI=1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10,14-15H,3-6,11H2,1-2H3,(H2,22,27)(H,25,26)/t14-,15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography				J Med Chem 55: 10610-29 (2012) Article DOI: 10.1021/jm301296t BindingDB Entry DOI: 10.7270/Q2XD12T3
					More data for this Ligand-Target Pair