BDBM61647 MLS001030592::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-(4-methyl-1-piperidinyl)-6-thieno[2,3-d]pyrimidinecarboxamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-(4-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-(4-methylpiperidino)thieno[2,3-d]pyrimidine-6-carboxamide::SMR000635352::cid_4137407

SMILES: CC1CCN(CC1)c1nc(C)nc2sc(C(=O)Nc3ccc4OCCOc4c3)c(C)c12

InChI Key: InChIKey=QBGFNQXJGAXHGH-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 61647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM61647 (MLS001030592 | N-(2,3-dihydro-1,4-benzodioxin-6-yl...) Show SMILES CC1CCN(CC1)c1nc(C)nc2sc(C(=O)Nc3ccc4OCCOc4c3)c(C)c12 Show InChI InChI=1S/C23H26N4O3S/c1-13-6-8-27(9-7-13)21-19-14(2)20(31-23(19)25-15(3)24-21)22(28)26-16-4-5-17-18(12-16)30-11-10-29-17/h4-5,12-13H,6-11H2,1-3H3,(H,26,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TQ5ZZB
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM61647 (MLS001030592 | N-(2,3-dihydro-1,4-benzodioxin-6-yl...) Show SMILES CC1CCN(CC1)c1nc(C)nc2sc(C(=O)Nc3ccc4OCCOc4c3)c(C)c12 Show InChI InChI=1S/C23H26N4O3S/c1-13-6-8-27(9-7-13)21-19-14(2)20(31-23(19)25-15(3)24-21)22(28)26-16-4-5-17-18(12-16)30-11-10-29-17/h4-5,12-13H,6-11H2,1-3H3,(H,26,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Dr. Mary Abood Source Affiliation: Temple University Network: NIH Molecular Libraries Probe Production Centers Network (MLPCN) Grant Pro...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q27S7M6H
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM61647 (MLS001030592 | N-(2,3-dihydro-1,4-benzodioxin-6-yl...) Show SMILES CC1CCN(CC1)c1nc(C)nc2sc(C(=O)Nc3ccc4OCCOc4c3)c(C)c12 Show InChI InChI=1S/C23H26N4O3S/c1-13-6-8-27(9-7-13)21-19-14(2)20(31-23(19)25-15(3)24-21)22(28)26-16-4-5-17-18(12-16)30-11-10-29-17/h4-5,12-13H,6-11H2,1-3H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2F47MKR
					More data for this Ligand-Target Pair
G-protein coupled receptor 55 (Homo sapiens (Human))	BDBM61647 (MLS001030592 | N-(2,3-dihydro-1,4-benzodioxin-6-yl...) Show SMILES CC1CCN(CC1)c1nc(C)nc2sc(C(=O)Nc3ccc4OCCOc4c3)c(C)c12 Show InChI InChI=1S/C23H26N4O3S/c1-13-6-8-27(9-7-13)21-19-14(2)20(31-23(19)25-15(3)24-21)22(28)26-16-4-5-17-18(12-16)30-11-10-29-17/h4-5,12-13H,6-11H2,1-3H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics(SSBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2028PZ5
					More data for this Ligand-Target Pair