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SMILES: CN(CCCON1C(N)=NC(N)=NC11CCCC1)c1ccccc1

InChI Key: InChIKey=QOKSKPMJRHYCOE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 82110   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydrofolate reductase


(Bos taurus (Cattle))		BDBM82110
PNG
(6,8,10-Traiazaspiro[4.5]deca-6,8-diene-7,9-diamine...)
Show SMILES CN(CCCON1C(N)=NC(N)=NC11CCCC1)c1ccccc1 |c:8,11|
Show InChI InChI=1S/C17H26N6O/c1-22(14-8-3-2-4-9-14)12-7-13-24-23-16(19)20-15(18)21-17(23)10-5-6-11-17/h2-4,8-9H,5-7,10-13H2,1H3,(H4,18,19,20,21)
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Article
PubMed
n/an/a 14.9n/an/an/an/an/an/a



National University of Singapore



Assay Description
Inhibition activity using bovine dihydrofolate reductase (DHFR).

Chem Biol Drug Des 74: 322-6 (2009)


Article DOI: 10.1111/j.1747-0285.2009.00860.x
BindingDB Entry DOI: 10.7270/Q24F1P74
More data for this
Ligand-Target Pair