BindingDB PrimarySearch

null

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 82 hits for monomerid = 82258
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research Curated by ChEMBL					Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...				J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against AT1 receptor binding affinity in rat liver				J Med Chem 36: 2253-65 (1993) Article DOI: 10.1021/jm00068a002 BindingDB Entry DOI: 10.7270/Q25H7JGW
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against binding of [125I]angiotensin II to rat liver expressing Angiotensin II receptor				J Med Chem 36: 2253-65 (1993) Article DOI: 10.1021/jm00068a002 BindingDB Entry DOI: 10.7270/Q25H7JGW
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against [125I]angiotensin II(AII) induced contraction in rabbit aorta by 50%				J Med Chem 36: 2253-65 (1993) Article DOI: 10.1021/jm00068a002 BindingDB Entry DOI: 10.7270/Q25H7JGW
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of monoiodinated angiotensin II from guinea-pig adrenal gland angiotensin II receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2PG1TWM
TBA					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research Curated by ChEMBL					Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...				J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1
					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research Curated by ChEMBL					Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...				J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1
					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cells				Hepatology 60: 1015-22 (2014) Article DOI: 10.1002/hep.27206 BindingDB Entry DOI: 10.7270/Q2TF00N2
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...				Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [125I]AII binding to guinea pig adrenal membrane				Citation and Details Article DOI: 10.1016/S0960-894X(01)81136-7 BindingDB Entry DOI: 10.7270/Q22V2JSJ
TBA					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested in vitro for inhibition of [125I]AII to rat uterine membranes				Citation and Details Article DOI: 10.1016/S0960-894X(01)81129-X BindingDB Entry DOI: 10.7270/Q2PN98BK
TBA					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro inhibitory activity against rat Angiotensin II receptor, type 1 expressed in CHO cells				J Med Chem 42: 4524-37 (1999) Article DOI: 10.1021/jm991089q BindingDB Entry DOI: 10.7270/Q2PN98C1
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.				J Med Chem 37: 542-50 (1994) Article DOI: 10.1021/jm00030a013 BindingDB Entry DOI: 10.7270/Q2R78HX6
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.				J Med Chem 46: 716-26 (2003) Article DOI: 10.1021/jm021032v BindingDB Entry DOI: 10.7270/Q22B91RC
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibitory concentration against [125 I]Ang II binding to rat pituitary membranes Angiotensin II receptor type 1 without 0.2% bovine serum albumin				J Med Chem 40: 903-19 (1997) Article DOI: 10.1021/jm960553d BindingDB Entry DOI: 10.7270/Q28S4SM4
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of rats				J Med Chem 38: 4670-8 (1995) Article DOI: 10.1021/jm00023a006 BindingDB Entry DOI: 10.7270/Q21J9DHJ
Burroughs Wellcome Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Institute of Technology Curated by ChEMBL					Assay Description Displacement of [125I]Sar1Ile8-Ang2 from human AT1 receptor expressed in CHO-K1 cell membranes after 180 mins				Eur J Med Chem 103: 473-87 (2015) Article DOI: 10.1016/j.ejmech.2015.09.010 BindingDB Entry DOI: 10.7270/Q21J9DS4
Beijing Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Biopharma US Inc. Curated by ChEMBL					Assay Description Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...				ACS Med Chem Lett 10: 86-91 (2019) Article DOI: 10.1021/acsmedchemlett.8b00462 BindingDB Entry DOI: 10.7270/Q2D50R6V
Theravance Biopharma US Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibition of ATR1 (unknown origin)				J Med Chem 62: 8915-8930 (2019) Article DOI: 10.1021/acs.jmedchem.9b00179 BindingDB Entry DOI: 10.7270/Q2377CZQ
University of Basel Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysis				Eur J Med Chem 62: 352-70 (2013) Article DOI: 10.1016/j.ejmech.2012.12.044 BindingDB Entry DOI: 10.7270/Q2DF6V47
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Mus musculus)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya University Curated by ChEMBL					Assay Description Antagonist activity at HA-tagged mouse AT1a angiotensin 2 receptor expressed in HEK293T cells assessed as decrease in angiotensin 2-induced intracell...				Bioorg Med Chem 16: 7843-52 (2008) Article DOI: 10.1016/j.bmc.2008.03.056 BindingDB Entry DOI: 10.7270/Q2TT4TQ6
Nagoya University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Institute of Technology Curated by ChEMBL					Assay Description Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysis				Eur J Med Chem 69: 44-54 (2013) Article DOI: 10.1016/j.ejmech.2013.08.014 BindingDB Entry DOI: 10.7270/Q2PK0K32
Beijing Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Institute of Technology Curated by ChEMBL					Assay Description Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT2 receptor (unknown origin) after 180 mins by gamma counting analysis				Eur J Med Chem 69: 44-54 (2013) Article DOI: 10.1016/j.ejmech.2013.08.014 BindingDB Entry DOI: 10.7270/Q2PK0K32
Beijing Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
Japan Biological Informatics Consortium (JBIC) Curated by ChEMBL					Assay Description Binding affinity to human N-terminal Ig-like domain D1D2 GPVI expressed in Escherichia coli DH5alpha by NMR spectroscopy				J Med Chem 53: 2087-93 (2010) Article DOI: 10.1021/jm901534d BindingDB Entry DOI: 10.7270/Q21C20PF
					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BSEP expressed in HEK293 cell membrane vesicles assessed as reduction in 3H-TCA uptake incubated for 5 mins by radiodetection met...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00524 BindingDB Entry DOI: 10.7270/Q2TX3JZP
TBA					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at GP6 in human platelet assessed as reduction in collagen-induced platelet-aggregation preincubated for 60 secs followed by coll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00262 BindingDB Entry DOI: 10.7270/Q2V128FM
TBA					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at GP6 in human platelet assessed as reduction in CRP-induced platelet-aggregation preincubated for 60 secs followed by collagen ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00262 BindingDB Entry DOI: 10.7270/Q2V128FM
TBA					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant GP6 (unknown origin) at protein to compound ratio of 1 : 1 to 1 : 10 by 2D 15N-1H TROSY-HSQC NMR spectroscopy				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00262 BindingDB Entry DOI: 10.7270/Q2V128FM
TBA					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of TxA2 receptor in human platelets assessed as reduction in U46619-induced platelet aggregation preincubated for 5 min followed by U46619...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00262 BindingDB Entry DOI: 10.7270/Q2V128FM
TBA					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d2md00206j BindingDB Entry DOI: 10.7270/Q2PC36F2
TBA					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114346 BindingDB Entry DOI: 10.7270/Q2PZ5DT3
TBA					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair

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