Found 12 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysine-specific demethylase 5A
(Homo sapiens (Human)) | BDBM50163389
(CHEMBL3793278)Show InChI InChI=1S/C5H6N4O2/c6-9-5-7-2-1-3(8-5)4(10)11/h1-2H,6H2,(H,10,11)(H,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of KDM5A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs... |
Bioorg Med Chem Lett 26: 2284-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.048 BindingDB Entry DOI: 10.7270/Q2XP76TS |
More data for this Ligand-Target Pair | |
Probable JmjC domain-containing histone demethylation protein 2C
(Homo sapiens (Human)) | BDBM50163389
(CHEMBL3793278)Show InChI InChI=1S/C5H6N4O2/c6-9-5-7-2-1-3(8-5)4(10)11/h1-2H,6H2,(H,10,11)(H,7,8,9) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of KDM3C (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs... |
Bioorg Med Chem Lett 26: 2284-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.048 BindingDB Entry DOI: 10.7270/Q2XP76TS |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 4E
(Homo sapiens (Human)) | BDBM50163389
(CHEMBL3793278)Show InChI InChI=1S/C5H6N4O2/c6-9-5-7-2-1-3(8-5)4(10)11/h1-2H,6H2,(H,10,11)(H,7,8,9) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of KDM4E (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs... |
Bioorg Med Chem Lett 26: 2284-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.048 BindingDB Entry DOI: 10.7270/Q2XP76TS |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 3A
(Homo sapiens (Human)) | BDBM50163389
(CHEMBL3793278)Show InChI InChI=1S/C5H6N4O2/c6-9-5-7-2-1-3(8-5)4(10)11/h1-2H,6H2,(H,10,11)(H,7,8,9) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of KDM3A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs... |
Bioorg Med Chem Lett 26: 2284-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.048 BindingDB Entry DOI: 10.7270/Q2XP76TS |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 6B
(Homo sapiens (Human)) | BDBM50163389
(CHEMBL3793278)Show InChI InChI=1S/C5H6N4O2/c6-9-5-7-2-1-3(8-5)4(10)11/h1-2H,6H2,(H,10,11)(H,7,8,9) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of KDM6B (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs... |
Bioorg Med Chem Lett 26: 2284-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.048 BindingDB Entry DOI: 10.7270/Q2XP76TS |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5B
(Homo sapiens (Human)) | BDBM50163389
(CHEMBL3793278)Show InChI InChI=1S/C5H6N4O2/c6-9-5-7-2-1-3(8-5)4(10)11/h1-2H,6H2,(H,10,11)(H,7,8,9) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of KDM5B (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs... |
Bioorg Med Chem Lett 26: 2284-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.048 BindingDB Entry DOI: 10.7270/Q2XP76TS |
More data for this Ligand-Target Pair | |
Probable JmjC domain-containing histone demethylation protein 2C
(Homo sapiens (Human)) | BDBM50594963
(CHEMBL5191875)Show SMILES [H][C@]12OC[C@H](NS(=O)(=O)c3ccc(NC(C)=O)cc3)[C@@]1([H])OC[C@@H]2Nc1nccc(n1)-c1cccc(F)c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 2.67E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |
Probable JmjC domain-containing histone demethylation protein 2C
(Homo sapiens (Human)) | BDBM50594964
(CHEMBL5193187)Show SMILES [H][C@]12OC[C@H](NS(=O)(=O)c3ccc(NC(C)=O)cc3)[C@@]1([H])OC[C@@H]2Nc1nccc(n1)-c1ccccc1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |
Probable JmjC domain-containing histone demethylation protein 2C
(Homo sapiens (Human)) | BDBM50594965
(CHEMBL5173150)Show SMILES [H][C@]12OC[C@H](NS(=O)(=O)c3ccc(NC(C)=O)cc3)[C@@]1([H])OC[C@@H]2Nc1nccc(n1)-c1cccc(c1)C(C)(C)C |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 8.06E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 3B
(Homo sapiens (Human)) | BDBM50594963
(CHEMBL5191875)Show SMILES [H][C@]12OC[C@H](NS(=O)(=O)c3ccc(NC(C)=O)cc3)[C@@]1([H])OC[C@@H]2Nc1nccc(n1)-c1cccc(F)c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 1.63E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 3B
(Homo sapiens (Human)) | BDBM50594964
(CHEMBL5193187)Show SMILES [H][C@]12OC[C@H](NS(=O)(=O)c3ccc(NC(C)=O)cc3)[C@@]1([H])OC[C@@H]2Nc1nccc(n1)-c1ccccc1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 3B
(Homo sapiens (Human)) | BDBM50594965
(CHEMBL5173150)Show SMILES [H][C@]12OC[C@H](NS(=O)(=O)c3ccc(NC(C)=O)cc3)[C@@]1([H])OC[C@@H]2Nc1nccc(n1)-c1cccc(c1)C(C)(C)C |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 7.79E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |