Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50032737 (CHEMBL3354718) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061587 (CHEMBL3394051) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061582 (CHEMBL3394039) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061593 (CHEMBL3394040) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061594 (CHEMBL3394041) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061595 (CHEMBL3394042) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061598 (CHEMBL3394045) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061583 (CHEMBL3394047) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061584 (CHEMBL3394048) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061585 (CHEMBL3394049) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061586 (CHEMBL3394050) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061588 (CHEMBL3394052) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061589 (CHEMBL3394053) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061590 (CHEMBL3394054) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061591 (CHEMBL3394055) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061592 (CHEMBL3394056) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061580 (CHEMBL3394057) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50061581 (CHEMBL3394058) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372815 ((1R,5S,6S)-5-(5-((Z)-2-(5-(but-2-yn-1-yloxy)pyrazi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50032737 (CHEMBL3354718) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372897 (((1S,5S,6S)-3-amino-5-(2-fluoro-5-((Z)-2-fluoro-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372830 ((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-(but-2-yn-1-ylox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372886 (((1S,5S,6S)-3-amino-5-(2-fluoro-5-((Z)-2-fluoro-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372833 ((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-(but-2-yn-1-ylox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50061594 (CHEMBL3394041) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50061587 (CHEMBL3394051) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372723 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((S)-3-fluoropyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.509 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372722 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((R)-3-fluoropyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.518 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372731 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((4aS,8aR)-decah...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.527 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372721 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((S)-3-hydroxypy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.592 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372811 ((1R,5S,6S)-5-(2-fluoro-5-((Z)-2-fluoro-2-(5-(prop-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372898 (((1S,5S,6S)-3-amino-5-(2-fluoro-5-((Z)-2-fluoro-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372903 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((S)-3-hydroxy-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50061585 (CHEMBL3394049) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372703 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(pyrrol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.673 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50061582 (CHEMBL3394039) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50061584 (CHEMBL3394048) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372735 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(4-(tri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.744 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372743 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(4-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.793 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372928 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((R)-3-hydroxypy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372883 ((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-(but-2-yn-1-ylox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372922 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(1-oxa-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372889 (((1S,5S,6S)-3-amino-5-(2-fluoro-5-((Z)-2-fluoro-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372755 ((1S,5S,6S)-3-amino-5-(5-((Z)-2-(5-(cyclopropylethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.856 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372742 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.863 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372741 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.867 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50061593 (CHEMBL3394040) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of BACE1 (unknown origin) by fluorescence assay | Bioorg Med Chem Lett 25: 767-74 (2015) Article DOI: 10.1016/j.bmcl.2014.12.092 BindingDB Entry DOI: 10.7270/Q21G0NXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372891 (((1S,5S,6S)-3-amino-5-(2-fluoro-5-((Z)-2-fluoro-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372903 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-1-((S)-3-hydroxy-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ... | J Med Chem 49: 6652-5 (2006) BindingDB Entry DOI: 10.7270/Q23J3G8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM372703 (6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(pyrrol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human BACE1 using fluorescence substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127240 BindingDB Entry DOI: 10.7270/Q2Z323C8 | |||||||||||
More data for this Ligand-Target Pair |
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