Compile Data Set for Download or QSAR

Found 175 hits with Last Name = 'canales' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Non-competitive inhibition of human recombinant MAGL assessed as 7-hydroxycoumarin level using umbelliferyl arachidonate as substrate by luminescence...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50464942 (CHEMBL4293015) Show SMILES Cn1cc(CC(=O)NCCC2CCN(Cc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H31N3O/c1-27-19-22(23-9-5-6-10-24(23)27)17-25(29)26-14-11-20-12-15-28(16-13-20)18-21-7-3-2-4-8-21/h2-10,19-20H,11-18H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50464944 (CHEMBL4285818) Show SMILES Brc1ccc2[nH]cc(CC(=O)NCCC3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C24H28BrN3O/c25-21-6-7-23-22(15-21)20(16-27-23)14-24(29)26-11-8-18-9-12-28(13-10-18)17-19-4-2-1-3-5-19/h1-7,15-16,18,27H,8-14,17H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50464946 (CHEMBL4283651) Show SMILES O=C(Cc1c[nH]c2ccccc12)NCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C24H29N3O/c28-24(16-21-17-26-23-9-5-4-8-22(21)23)25-13-10-19-11-14-27(15-12-19)18-20-6-2-1-3-7-20/h1-9,17,19,26H,10-16,18H2,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50187201 (CHEMBL3824248) Show SMILES O=C(CCc1c[nH]c2ccccc12)NCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H31N3O/c29-25(11-10-22-18-27-24-9-5-4-8-23(22)24)26-15-12-20-13-16-28(17-14-20)19-21-6-2-1-3-7-21/h1-9,18,20,27H,10-17,19H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50464947 (CHEMBL4277879) Show SMILES Cc1[nH]c2ccccc2c1CC(=O)NCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H31N3O/c1-19-23(22-9-5-6-10-24(22)27-19)17-25(29)26-14-11-20-12-15-28(16-13-20)18-21-7-3-2-4-8-21/h2-10,20,27H,11-18H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 ...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cholinesterase (Homo sapiens (Human))	BDBM50464943 (CHEMBL4294109) Show SMILES O=C(CCCc1c[nH]c2ccccc12)NCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C26H33N3O/c30-26(12-6-9-23-19-28-25-11-5-4-10-24(23)25)27-16-13-21-14-17-29(18-15-21)20-22-7-2-1-3-8-22/h1-5,7-8,10-11,19,21,28H,6,9,12-18,20H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	288	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379255 (CHEMBL2011480) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379255 (CHEMBL2011480) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379250 (CHEMBL2011307) Show SMILES O=C(Cc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C17H16O3/c18-17(20-12-16-11-19-16)10-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16H,10-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379250 (CHEMBL2011307) Show SMILES O=C(Cc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C17H16O3/c18-17(20-12-16-11-19-16)10-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16H,10-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50464945 (CHEMBL4282414) Show SMILES Cn1cc(C(=O)NCCC2CCN(Cc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C24H29N3O/c1-26-18-22(21-9-5-6-10-23(21)26)24(28)25-14-11-19-12-15-27(16-13-19)17-20-7-3-2-4-8-20/h2-10,18-19H,11-17H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measure...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	676	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379242 (CHEMBL2011482) Show SMILES OCC(CO)OC(=O)Cc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C18H20O4/c19-12-17(13-20)22-18(21)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17,19-20H,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379242 (CHEMBL2011482) Show SMILES OCC(CO)OC(=O)Cc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C18H20O4/c19-12-17(13-20)22-18(21)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17,19-20H,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379248 (CHEMBL2011309) Show SMILES O=C(CCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-13-21-18)8-4-5-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-3,6-7,9-12,18H,4-5,8,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379248 (CHEMBL2011309) Show SMILES O=C(CCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-13-21-18)8-4-5-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-3,6-7,9-12,18H,4-5,8,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379231 (CHEMBL2011319) Show SMILES O=C(OCC1CCCCO1)\C=C\c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H22O3/c22-21(24-16-20-8-4-5-15-23-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-3,6-7,9-14,20H,4-5,8,15-16H2/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	759	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379231 (CHEMBL2011319) Show SMILES O=C(OCC1CCCCO1)\C=C\c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H22O3/c22-21(24-16-20-8-4-5-15-23-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-3,6-7,9-14,20H,4-5,8,15-16H2/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379251 (CHEMBL2011308) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,17H,8,11-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379251 (CHEMBL2011308) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,17H,8,11-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	871	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50464943 (CHEMBL4294109) Show SMILES O=C(CCCc1c[nH]c2ccccc12)NCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C26H33N3O/c30-26(12-6-9-23-19-28-25-11-5-4-10-24(23)25)27-16-13-21-14-17-29(18-15-21)20-22-7-2-1-3-8-22/h1-5,7-8,10-11,19,21,28H,6,9,12-18,20H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 ...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50464944 (CHEMBL4285818) Show SMILES Brc1ccc2[nH]cc(CC(=O)NCCC3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C24H28BrN3O/c25-21-6-7-23-22(15-21)20(16-27-23)14-24(29)26-11-8-18-9-12-28(13-10-18)17-19-4-2-1-3-5-19/h1-7,15-16,18,27H,8-14,17H2,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 ...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50464942 (CHEMBL4293015) Show SMILES Cn1cc(CC(=O)NCCC2CCN(Cc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H31N3O/c1-27-19-22(23-9-5-6-10-24(23)27)17-25(29)26-14-11-20-12-15-28(16-13-20)18-21-7-3-2-4-8-21/h2-10,19-20H,11-18H2,1H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 ...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379246 (CHEMBL2011481) Show SMILES OCC(CO)OC(=O)CCCCCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H26O4/c22-15-20(16-23)25-21(24)10-6-1-3-7-17-11-13-19(14-12-17)18-8-4-2-5-9-18/h2,4-5,8-9,11-14,20,22-23H,1,3,6-7,10,15-16H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379246 (CHEMBL2011481) Show SMILES OCC(CO)OC(=O)CCCCCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H26O4/c22-15-20(16-23)25-21(24)10-6-1-3-7-17-11-13-19(14-12-17)18-8-4-2-5-9-18/h2,4-5,8-9,11-14,20,22-23H,1,3,6-7,10,15-16H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379252 (CHEMBL2011314) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)OCC1CCCCO1 Show InChI InChI=1S/C21H24O3/c22-21(24-16-20-8-4-5-15-23-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-3,6-7,9-10,12-13,20H,4-5,8,11,14-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379252 (CHEMBL2011314) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)OCC1CCCCO1 Show InChI InChI=1S/C21H24O3/c22-21(24-16-20-8-4-5-15-23-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-3,6-7,9-10,12-13,20H,4-5,8,11,14-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379239 (CHEMBL2011477) Show SMILES O=C(CCCCCc1ccc(cc1)-c1ccccc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C21H24O3/c22-21(24-16-20-15-23-20)10-6-1-3-7-17-11-13-19(14-12-17)18-8-4-2-5-9-18/h2,4-5,8-9,11-14,20H,1,3,6-7,10,15-16H2/t20-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379248 (CHEMBL2011309) Show SMILES O=C(CCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-13-21-18)8-4-5-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-3,6-7,9-12,18H,4-5,8,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379248 (CHEMBL2011309) Show SMILES O=C(CCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-13-21-18)8-4-5-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-3,6-7,9-12,18H,4-5,8,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379239 (CHEMBL2011477) Show SMILES O=C(CCCCCc1ccc(cc1)-c1ccccc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C21H24O3/c22-21(24-16-20-15-23-20)10-6-1-3-7-17-11-13-19(14-12-17)18-8-4-2-5-9-18/h2,4-5,8-9,11-14,20H,1,3,6-7,10,15-16H2/t20-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379246 (CHEMBL2011481) Show SMILES OCC(CO)OC(=O)CCCCCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H26O4/c22-15-20(16-23)25-21(24)10-6-1-3-7-17-11-13-19(14-12-17)18-8-4-2-5-9-18/h2,4-5,8-9,11-14,20,22-23H,1,3,6-7,10,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379246 (CHEMBL2011481) Show SMILES OCC(CO)OC(=O)CCCCCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H26O4/c22-15-20(16-23)25-21(24)10-6-1-3-7-17-11-13-19(14-12-17)18-8-4-2-5-9-18/h2,4-5,8-9,11-14,20,22-23H,1,3,6-7,10,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379234 (CHEMBL2011323) Show SMILES O=C(CCc1ccc(Cc2ccccc2)cc1)OCC1CO1 Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-13-21-18)11-10-15-6-8-17(9-7-15)12-16-4-2-1-3-5-16/h1-9,18H,10-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379234 (CHEMBL2011323) Show SMILES O=C(CCc1ccc(Cc2ccccc2)cc1)OCC1CO1 Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-13-21-18)11-10-15-6-8-17(9-7-15)12-16-4-2-1-3-5-16/h1-9,18H,10-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379247 (CHEMBL2011310) Show SMILES O=C(CCCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C20H22O3/c21-20(23-15-19-14-22-19)9-5-4-6-16-10-12-18(13-11-16)17-7-2-1-3-8-17/h1-3,7-8,10-13,19H,4-6,9,14-15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50379247 (CHEMBL2011310) Show SMILES O=C(CCCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C20H22O3/c21-20(23-15-19-14-22-19)9-5-4-6-16-10-12-18(13-11-16)17-7-2-1-3-8-17/h1-3,7-8,10-13,19H,4-6,9,14-15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379245 (CHEMBL2011312) Show SMILES O=C(CCCCCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C22H26O3/c23-22(25-17-21-16-24-21)11-7-2-1-4-8-18-12-14-20(15-13-18)19-9-5-3-6-10-19/h3,5-6,9-10,12-15,21H,1-2,4,7-8,11,16-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379245 (CHEMBL2011312) Show SMILES O=C(CCCCCCc1ccc(cc1)-c1ccccc1)OCC1CO1 Show InChI InChI=1S/C22H26O3/c23-22(25-17-21-16-24-21)11-7-2-1-4-8-18-12-14-20(15-13-18)19-9-5-3-6-10-19/h3,5-6,9-10,12-15,21H,1-2,4,7-8,11,16-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50464946 (CHEMBL4283651) Show SMILES O=C(Cc1c[nH]c2ccccc12)NCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C24H29N3O/c28-24(16-21-17-26-23-9-5-4-8-22(21)23)25-13-10-19-11-14-27(15-12-19)18-20-6-2-1-3-7-20/h1-9,17,19,26H,10-16,18H2,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of S£o Paulo Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 ...				Eur J Med Chem 145: 431-444 (2018) Article DOI: 10.1016/j.ejmech.2018.01.007 BindingDB Entry DOI: 10.7270/Q2JQ13PD
					More data for this Ligand-Target Pair
Monoglyceride lipase (Rattus norvegicus (Rat))	BDBM50379235 (CHEMBL2011324) Show SMILES O=C(CCCc1ccc(Cc2ccccc2)cc1)OCC1CO1 Show InChI InChI=1S/C20H22O3/c21-20(23-15-19-14-22-19)8-4-7-16-9-11-18(12-10-16)13-17-5-2-1-3-6-17/h1-3,5-6,9-12,19H,4,7-8,13-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopy				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair

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