Compile Data Set for Download or QSAR

Found 11 hits with Last Name = 'yliniemelä' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50036286 ((R)-(-)-10-methyl-11-hydroxyaporphine | (R)-6,10-d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 Show InChI InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	41.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-raclopride binding to cloned human Dopamine receptor D2A				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-raclopride binding to cloned human Dopamine receptor D2A				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50036286 ((R)-(-)-10-methyl-11-hydroxyaporphine | (R)-6,10-d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 Show InChI InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	382	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50036286 ((R)-(-)-10-methyl-11-hydroxyaporphine | (R)-6,10-d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 Show InChI InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to displace [3H]-raclopride binding to cloned human Dopamine receptor D2A				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016013 ((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to inhibit 5-HT sensitive,forskolin-stimulated adenylyl cyclase(FSC) activity in rat hippocampal membranes mediated through 5-hydroxytryptami...				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50036286 ((R)-(-)-10-methyl-11-hydroxyaporphine | (R)-6,10-d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 Show InChI InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Ability to inhibit 5-HT sensitive,forskolin-stimulated adenylyl cyclase(FSC) activity in rat hippocampal membranes mediated through 5-hydroxytryptami...				J Med Chem 38: 647-58 (1995) BindingDB Entry DOI: 10.7270/Q2HX1BQH
					More data for this Ligand-Target Pair