Compile Data Set for Download or QSAR

Found 82 hits with Last Name = 'genazzani' and Initial = 'aa'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM81395 (APO-866) Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Noncompetitive inhibition of NAMPT (unknown origin)				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439676 (CHEMBL2417796) Show SMILES CN1CCN(Cc2nc3cc(Br)c(CN(CC#C)c4ccc(cc4)C(=O)NCc4cccnc4)cc3c(=O)n2C)CC1 Show InChI InChI=1S/C32H34BrN7O2/c1-4-12-40(26-9-7-24(8-10-26)31(41)35-20-23-6-5-11-34-19-23)21-25-17-27-29(18-28(25)33)36-30(38(3)32(27)42)22-39-15-13-37(2)14-16-39/h1,5-11,17-19H,12-16,20-22H2,2-3H3,(H,35,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT (unknown origin)				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50347432 (CHEMBL1801863) Show SMILES Cn1c(CN2CCN(CCCN)CC2)nc2cc(Cl)c(CN(CC#C)c3ccc(cc3)C(=O)NCc3cccnc3)cc2c1=O Show InChI InChI=1S/C34H39ClN8O2/c1-3-13-43(28-9-7-26(8-10-28)33(44)38-22-25-6-4-12-37-21-25)23-27-19-29-31(20-30(27)35)39-32(40(2)34(29)45)24-42-17-15-41(16-18-42)14-5-11-36/h1,4,6-10,12,19-21H,5,11,13-18,22-24,36H2,2H3,(H,38,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT (unknown origin)				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50347433 (CHEMBL1801864) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#7](-[#6]-c1cc2c(cc1Cl)nnn(-[#6])c2=O)-c1ccc(cc1)-[#6](=O)-[#7]-[#6]-c1cccnc1 Show InChI InChI=1S/C27H27ClN6O2/c1-18(2)10-12-34(17-21-13-23-25(14-24(21)28)31-32-33(3)27(23)36)22-8-6-20(7-9-22)26(35)30-16-19-5-4-11-29-15-19/h4-11,13-15H,12,16-17H2,1-3H3,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT (unknown origin)				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439675 (CHEMBL2417788 | US11279687, Compound 196) Show SMILES FC(F)(F)Oc1ccccc1S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1 Show InChI InChI=1S/C20H16F3N3O4S/c21-20(22,23)30-17-5-1-2-6-18(17)31(28,29)16-9-7-15(8-10-16)26-19(27)25-13-14-4-3-11-24-12-14/h1-12H,13H2,(H2,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT (unknown origin)				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439678 (CHEMBL2417789) Show SMILES Clc1cccc(c1)S(=O)(=O)c1ccc(CNC(NC#N)=Nc2ccncc2)cc1 |w:20.21| Show InChI InChI=1S/C20H16ClN5O2S/c21-16-2-1-3-19(12-16)29(27,28)18-6-4-15(5-7-18)13-24-20(25-14-22)26-17-8-10-23-11-9-17/h1-12H,13H2,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 mins				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM81395 (APO-866) Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439677 (CHEMBL2417790 | US9169209, Table 3, Compound 55) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C20H16N2O3S/c23-20(13-8-16-5-4-14-21-15-16)22-17-9-11-19(12-10-17)26(24,25)18-6-2-1-3-7-18/h1-15H,(H,22,23)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 mins				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236217 (CHEMBL4061448) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H29N5O/c33-27(25-16-8-7-15-24(25)22-12-5-4-6-13-22)29-18-9-2-1-3-10-19-32-21-26(30-31-32)23-14-11-17-28-20-23/h4-8,11-17,20-21H,1-3,9-10,18-19H2,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515548 (CHEMBL4458472) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-n1ccnn1 Show InChI InChI=1S/C23H26N8O/c32-23(20-10-4-5-11-22(20)31-16-14-26-28-31)25-13-6-2-1-3-7-15-30-18-21(27-29-30)19-9-8-12-24-17-19/h4-5,8-12,14,16-18H,1-3,6-7,13,15H2,(H,25,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236220 (CHEMBL4074848) Show SMILES C(CCCn1cc(nn1)-c1cccnc1)CCOc1ccccc1-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c1(8-17-29-20-24(27-28-29)22-13-10-16-26-19-22)2-9-18-30-25-15-7-6-14-23(25)21-11-4-3-5-12-21/h3-7,10-16,19-20H,1-2,8-9,17-18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50236217 (CHEMBL4061448) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H29N5O/c33-27(25-16-8-7-15-24(25)22-12-5-4-6-13-22)29-18-9-2-1-3-10-19-32-21-26(30-31-32)23-14-11-17-28-20-23/h4-8,11-17,20-21H,1-3,9-10,18-19H2,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levels				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM81395 (APO-866) Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439680 (CHEMBL2417798) Show SMILES Cc1ncsc1C(=O)N1CCC(CCCCNC(=O)c2cc3cnccc3[nH]2)CC1 Show InChI InChI=1S/C22H27N5O2S/c1-15-20(30-14-25-15)22(29)27-10-6-16(7-11-27)4-2-3-8-24-21(28)19-12-17-13-23-9-5-18(17)26-19/h5,9,12-14,16,26H,2-4,6-8,10-11H2,1H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 mins				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439679 (CHEMBL2417799) Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)c1cc2ccncc2s1 Show InChI InChI=1S/C24H27N3O2S/c28-23(21-16-20-9-13-25-17-22(20)30-21)26-12-5-4-6-18-10-14-27(15-11-18)24(29)19-7-2-1-3-8-19/h1-3,7-9,13,16-18H,4-6,10-12,14-15H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 mins				J Med Chem 56: 6279-96 (2013) Article DOI: 10.1021/jm4001049 BindingDB Entry DOI: 10.7270/Q25Q4XJ8
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50236220 (CHEMBL4074848) Show SMILES C(CCCn1cc(nn1)-c1cccnc1)CCOc1ccccc1-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c1(8-17-29-20-24(27-28-29)22-13-10-16-26-19-22)2-9-18-30-25-15-7-6-14-23(25)21-11-4-3-5-12-21/h3-7,10-16,19-20H,1-2,8-9,17-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levels				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50236219 (CHEMBL4066091) Show SMILES C(CCCn1cc(nn1)-c1cccnc1)CCCn1cc(nn1)-c1ccccc1-c1ccccc1 Show InChI InChI=1S/C28H29N7/c1(2-9-18-34-21-27(30-32-34)24-14-11-17-29-20-24)3-10-19-35-22-28(31-33-35)26-16-8-7-15-25(26)23-12-5-4-6-13-23/h4-8,11-17,20-22H,1-3,9-10,18-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levels				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236219 (CHEMBL4066091) Show SMILES C(CCCn1cc(nn1)-c1cccnc1)CCCn1cc(nn1)-c1ccccc1-c1ccccc1 Show InChI InChI=1S/C28H29N7/c1(2-9-18-34-21-27(30-32-34)24-14-11-17-29-20-24)3-10-19-35-22-28(31-33-35)26-16-8-7-15-25(26)23-12-5-4-6-13-23/h4-8,11-17,20-22H,1-3,9-10,18-19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515544 (CHEMBL4535593) Show SMILES CN1CCN(Cc2cn(nn2)-c2ccccc2C(=O)NCCCCCCCn2cc(nn2)-c2cccnc2)CC1 Show InChI InChI=1S/C29H38N10O/c1-36-16-18-37(19-17-36)21-25-22-39(35-32-25)28-12-6-5-11-26(28)29(40)31-14-7-3-2-4-8-15-38-23-27(33-34-38)24-10-9-13-30-20-24/h5-6,9-13,20,22-23H,2-4,7-8,14-19,21H2,1H3,(H,31,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236221 (CHEMBL4078882) Show SMILES C(Cc1ccc(Cn2cc(nn2)-c2cccnc2)cc1)Oc1ccccc1-c1ccccc1 Show InChI InChI=1S/C28H24N4O/c1-2-7-24(8-3-1)26-10-4-5-11-28(26)33-18-16-22-12-14-23(15-13-22)20-32-21-27(30-31-32)25-9-6-17-29-19-25/h1-15,17,19,21H,16,18,20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515540 (CHEMBL4470375) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-n1cc(CN2CCCCC2)nn1 Show InChI InChI=1S/C29H37N9O/c39-29(26-13-5-6-14-28(26)38-22-25(32-35-38)21-36-17-8-4-9-18-36)31-16-7-2-1-3-10-19-37-23-27(33-34-37)24-12-11-15-30-20-24/h5-6,11-15,20,22-23H,1-4,7-10,16-19,21H2,(H,31,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515543 (CHEMBL4464821) Show SMILES CCOC(=O)C1CCN(Cc2cn(nn2)-c2ccccc2C(=O)NCCCCCCCn2cc(nn2)-c2cccnc2)CC1 Show InChI InChI=1S/C32H41N9O3/c1-2-44-32(43)25-14-19-39(20-15-25)22-27-23-41(38-35-27)30-13-7-6-12-28(30)31(42)34-17-8-4-3-5-9-18-40-24-29(36-37-40)26-11-10-16-33-21-26/h6-7,10-13,16,21,23-25H,2-5,8-9,14-15,17-20,22H2,1H3,(H,34,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515551 (CHEMBL4446772) Show SMILES CC(C)N1CCN(Cc2cn(nn2)-c2ccccc2C(=O)NCCCCCCCn2cc(nn2)-c2cccnc2)CC1 Show InChI InChI=1S/C31H42N10O/c1-25(2)39-19-17-38(18-20-39)22-27-23-41(37-34-27)30-13-7-6-12-28(30)31(42)33-15-8-4-3-5-9-16-40-24-29(35-36-40)26-11-10-14-32-21-26/h6-7,10-14,21,23-25H,3-5,8-9,15-20,22H2,1-2H3,(H,33,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236223 (CHEMBL4083606) Show SMILES C(CCCCn1cc(nn1)-c1cccnc1)CCCOc1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H30N4O/c1(3-10-19-31-22-26(29-30-31)24-15-12-18-28-21-24)2-4-11-20-32-27-17-9-8-16-25(27)23-13-6-5-7-14-23/h5-9,12-18,21-22H,1-4,10-11,19-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515552 (CHEMBL4469394) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-n1cc(CN2CCCC2)nn1 Show InChI InChI=1S/C28H35N9O/c38-28(25-12-4-5-13-27(25)37-21-24(31-34-37)20-35-16-8-9-17-35)30-15-6-2-1-3-7-18-36-22-26(32-33-36)23-11-10-14-29-19-23/h4-5,10-14,19,21-22H,1-3,6-9,15-18,20H2,(H,30,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515556 (CHEMBL4555764) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-c1cccnc1 Show InChI InChI=1S/C26H28N6O/c33-26(24-13-5-4-12-23(24)21-10-8-14-27-18-21)29-16-6-2-1-3-7-17-32-20-25(30-31-32)22-11-9-15-28-19-22/h4-5,8-15,18-20H,1-3,6-7,16-17H2,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236222 (CHEMBL4101611) Show SMILES C(CCCOc1ccccc1-c1ccccc1)CCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C26H28N4O/c1(2-9-18-30-21-25(28-29-30)23-14-11-17-27-20-23)3-10-19-31-26-16-8-7-15-24(26)22-12-5-4-6-13-22/h4-8,11-17,20-21H,1-3,9-10,18-19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236224 (CHEMBL4088492) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)Nc1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H30N6O/c34-27(30-25-16-8-7-15-24(25)22-12-5-4-6-13-22)29-18-9-2-1-3-10-19-33-21-26(31-32-33)23-14-11-17-28-20-23/h4-8,11-17,20-21H,1-3,9-10,18-19H2,(H2,29,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515541 (CHEMBL4590810) Show SMILES OC(=O)c1ccccc1-c1ccccc1C(=O)NCCCCCCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C28H29N5O3/c34-27(24-14-6-4-12-22(24)23-13-5-7-15-25(23)28(35)36)30-17-8-2-1-3-9-18-33-20-26(31-32-33)21-11-10-16-29-19-21/h4-7,10-16,19-20H,1-3,8-9,17-18H2,(H,30,34)(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515545 (CHEMBL4440197) Show SMILES CN(C)Cc1cn(nn1)-c1ccccc1C(=O)NCCCCCCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C26H33N9O/c1-33(2)18-22-19-35(32-29-22)25-13-7-6-12-23(25)26(36)28-15-8-4-3-5-9-16-34-20-24(30-31-34)21-11-10-14-27-17-21/h6-7,10-14,17,19-20H,3-5,8-9,15-16,18H2,1-2H3,(H,28,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515546 (CHEMBL4577703) Show SMILES OC1CCN(Cc2cn(nn2)-c2ccccc2C(=O)NCCCCCCCn2cc(nn2)-c2cccnc2)CC1 Show InChI InChI=1S/C29H37N9O2/c39-25-12-17-36(18-13-25)20-24-21-38(35-32-24)28-11-5-4-10-26(28)29(40)31-15-6-2-1-3-7-16-37-22-27(33-34-37)23-9-8-14-30-19-23/h4-5,8-11,14,19,21-22,25,39H,1-3,6-7,12-13,15-18,20H2,(H,31,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515547 (CHEMBL4444551) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-c1c[nH]nn1 Show InChI InChI=1S/C23H26N8O/c32-23(20-11-5-4-10-19(20)21-16-26-29-27-21)25-13-6-2-1-3-7-14-31-17-22(28-30-31)18-9-8-12-24-15-18/h4-5,8-12,15-17H,1-3,6-7,13-14H2,(H,25,32)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236216 (CHEMBL4064240) Show SMILES O=S(=O)(NCCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H31N5O2S/c33-35(34,27-17-9-8-16-25(27)23-13-6-5-7-14-23)29-19-10-3-1-2-4-11-20-32-22-26(30-31-32)24-15-12-18-28-21-24/h5-9,12-18,21-22,29H,1-4,10-11,19-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236218 (CHEMBL4094769) Show SMILES O=C(CCCCCCCc1cc(on1)-c1cccnc1)Nc1ccccc1-c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c32-28(30-26-17-10-9-16-25(26)22-12-5-4-6-13-22)18-8-3-1-2-7-15-24-20-27(33-31-24)23-14-11-19-29-21-23/h4-6,9-14,16-17,19-21H,1-3,7-8,15,18H2,(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515542 (CHEMBL4569066) Show SMILES O=C(NCCCCCCCn1cc(nn1)-c1cccnc1)c1ccccc1-n1cc(CN2CCOCC2)nn1 Show InChI InChI=1S/C28H35N9O2/c38-28(25-10-4-5-11-27(25)37-21-24(31-34-37)20-35-15-17-39-18-16-35)30-13-6-2-1-3-7-14-36-22-26(32-33-36)23-9-8-12-29-19-23/h4-5,8-12,19,21-22H,1-3,6-7,13-18,20H2,(H,30,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515553 (CHEMBL4567518) Show SMILES OCCN(CCO)Cc1cn(nn1)-c1ccccc1C(=O)NCCCCCCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C28H37N9O3/c38-17-15-35(16-18-39)20-24-21-37(34-31-24)27-11-5-4-10-25(27)28(40)30-13-6-2-1-3-7-14-36-22-26(32-33-36)23-9-8-12-29-19-23/h4-5,8-12,19,21-22,38-39H,1-3,6-7,13-18,20H2,(H,30,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515550 (CHEMBL4462010) Show SMILES NC(=O)c1ccccc1-c1ccccc1C(=O)NCCCCCCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C28H30N6O2/c29-27(35)24-14-6-4-12-22(24)23-13-5-7-15-25(23)28(36)31-17-8-2-1-3-9-18-34-20-26(32-33-34)21-11-10-16-30-19-21/h4-7,10-16,19-20H,1-3,8-9,17-18H2,(H2,29,35)(H,31,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50461837 (CHEMBL4226608) Show SMILES [#6]-[#8]-c1cc(-[#6]-[#7]-[#6](=O)-[#6]-[#8]-[#6](=O)\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(I)cc1-[#8] Show InChI InChI=1S/C20H26INO5/c1-13(2)6-5-7-14(3)8-20(25)27-12-19(24)22-11-15-9-18(26-4)17(23)10-16(15)21/h6,8-10,23H,5,7,11-12H2,1-4H3,(H,22,24)/b14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Antagonist activity at TRPV1 (unknown origin) expressed in human SH-SY5Y cells assessed as inhibition of capsaicin-induced calcium increase after 25 ...				J Med Chem 61: 4436-4455 (2018) Article DOI: 10.1021/acs.jmedchem.8b00109 BindingDB Entry DOI: 10.7270/Q2PK0JSM
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein/Stromal interaction molecule 1 (Homo sapiens (Human))	BDBM50549365 (CHEMBL3403742) Show SMILES COc1ccc(OC)c(c1)-c1ccc(NC(=O)c2ccncc2F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium response				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01305 BindingDB Entry DOI: 10.7270/Q2HH6PPZ
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50236215 (CHEMBL4087071) Show SMILES O=C(CCCCCCCc1nnc([nH]1)-c1cccnc1)Nc1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H29N5O/c33-26(29-24-16-10-9-15-23(24)21-12-5-4-6-13-21)18-8-3-1-2-7-17-25-30-27(32-31-25)22-14-11-19-28-20-22/h4-6,9-16,19-20H,1-3,7-8,17-18H2,(H,29,33)(H,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi del Piemonte Orientale"A. Avogadro" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...				J Med Chem 60: 1768-1792 (2017) Article DOI: 10.1021/acs.jmedchem.6b01392 BindingDB Entry DOI: 10.7270/Q2TQ63TK
					More data for this Ligand-Target Pair
Short transient receptor potential channel 1 (Homo sapiens)	BDBM50450630 (CHEMBL101896) Show SMILES Fc1cnccc1C(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H9F7N4O/c18-12-8-25-6-5-11(12)15(29)26-9-1-3-10(4-2-9)28-14(17(22,23)24)7-13(27-28)16(19,20)21/h1-8H,(H,26,29)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...				J Med Chem 61: 9756-9783 (2018) Article DOI: 10.1021/acs.jmedchem.8b01512 BindingDB Entry DOI: 10.7270/Q2QV3Q2G
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein/Stromal interaction molecule 1 (Homo sapiens (Human))	BDBM50549358 (CHEMBL4753023) Show SMILES COc1ccc(F)c(c1)-c1ccc(cc1)-n1cc(nn1)-c1cccc(c1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	361	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium response				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01305 BindingDB Entry DOI: 10.7270/Q2HH6PPZ
					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi del Piemonte Orientale A. Avogadro Curated by ChEMBL					Assay Description Inhibition of HDAC in human SHSY5Y cells by fluorimetric cellular activity assay				J Med Chem 52: 2776-85 (2009) Article DOI: 10.1021/jm801529c BindingDB Entry DOI: 10.7270/Q2D221F1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Short transient receptor potential channel 1 (Homo sapiens)	BDBM50450629 (CHEMBL4177187) Show SMILES [#6]-[#6]-[#8]-[#6](=O)-c1cnn(c1C(F)(F)F)-c1ccc(-[#7]-[#6](=O)-[#6](\Cl)=[#6](/Cl)Cl)cc1 Show InChI InChI=1S/C16H11Cl3F3N3O3/c1-2-28-15(27)10-7-23-25(12(10)16(20,21)22)9-5-3-8(4-6-9)24-14(26)11(17)13(18)19/h3-7H,2H2,1H3,(H,24,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...				J Med Chem 61: 9756-9783 (2018) Article DOI: 10.1021/acs.jmedchem.8b01512 BindingDB Entry DOI: 10.7270/Q2QV3Q2G
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515555 (CHEMBL4070645) Show SMILES [O-][n+]1cccc(c1)-c1cn(CCCCCCCNC(=O)c2ccccc2-c2ccccc2)nn1 Show InChI InChI=1S/C27H29N5O2/c33-27(25-16-8-7-15-24(25)22-12-5-4-6-13-22)28-17-9-2-1-3-10-18-31-21-26(29-30-31)23-14-11-19-32(34)20-23/h4-8,11-16,19-21H,1-3,9-10,17-18H2,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515554 (CHEMBL4561248) Show SMILES OC(=O)c1cccc(c1)-c1ccccc1C(=O)NCCCCCCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C28H29N5O3/c34-27(25-14-5-4-13-24(25)21-10-8-11-22(18-21)28(35)36)30-16-6-2-1-3-7-17-33-20-26(31-32-33)23-12-9-15-29-19-23/h4-5,8-15,18-20H,1-3,6-7,16-17H2,(H,30,34)(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mus musculus)	BDBM50515549 (CHEMBL4555772) Show SMILES OC(=O)c1ccc(cc1)-c1ccccc1C(=O)NCCCCCCCn1cc(nn1)-c1cccnc1 Show InChI InChI=1S/C28H29N5O3/c34-27(25-11-5-4-10-24(25)21-12-14-22(15-13-21)28(35)36)30-17-6-2-1-3-7-18-33-20-26(31-32-33)23-9-8-16-29-19-23/h4-5,8-16,19-20H,1-3,6-7,17-18H2,(H,30,34)(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111576 BindingDB Entry DOI: 10.7270/Q22R3W15
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1/Short transient receptor potential channel 1/Short transient receptor potential channel 3/Stromal interaction molecule 1 (Homo sapiens (Human))	BDBM50450626 (CHEMBL4162723) Show SMILES CCOC(=O)c1cnn(c1C(F)(F)F)-c1ccc(cc1)-n1cc(nn1)-c1cccc(c1)C(O)=O Show InChI InChI=1S/C22H16F3N5O4/c1-2-34-21(33)17-11-26-30(19(17)22(23,24)25)16-8-6-15(7-9-16)29-12-18(27-28-29)13-4-3-5-14(10-13)20(31)32/h3-12H,2H2,1H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...				J Med Chem 61: 9756-9783 (2018) Article DOI: 10.1021/acs.jmedchem.8b01512 BindingDB Entry DOI: 10.7270/Q2QV3Q2G
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein/Stromal interaction molecule 1 (Homo sapiens (Human))	BDBM50549357 (CHEMBL4794288) Show SMILES COc1cccc(-c2ccc(cc2)-c2cn(nn2)-c2cccc(c2)C(O)=O)c1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	781	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium response				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01305 BindingDB Entry DOI: 10.7270/Q2HH6PPZ
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein/Stromal interaction molecule 1 (Homo sapiens (Human))	BDBM50549360 (CHEMBL4780000) Show SMILES COc1cc(OC)cc(c1)-c1ccc(cc1)-n1cc(nn1)-c1cccc(c1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	802	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium response				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01305 BindingDB Entry DOI: 10.7270/Q2HH6PPZ
					More data for this Ligand-Target Pair

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