BindingDB PrimarySearch

Found 34 hits with Last Name = 'speers' and Initial = 'ae'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM119872 (3‐(2‐ethoxypropyl)‐2‐sulfa...) Show SMILES CCOC(C)Cn1c2nc[nH]c2c(=O)[nH]c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	413	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Worldwide Research and Development					Assay Description Assay mixtures (100 µL) contained 50 mM NaPi (pH 7.4), 150 mM NaCl, 1 mM DTPA, 2% DMSO, the indicated concentrations of H2O2, and Amplex Red. Th...				Biochemistry 52: 9187-201 (2013) Article DOI: 10.1021/bi401354d BindingDB Entry DOI: 10.7270/Q2K35SBT
Pfizer Worldwide Research and Development					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM119874 (3‐[(2S)‐2‐ethoxypropyl]‐2&...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	429	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Worldwide Research and Development					Assay Description Assay mixtures (100 µL) contained 50 mM NaPi (pH 7.4), 150 mM NaCl, 1 mM DTPA, 2% DMSO, the indicated concentrations of H2O2, and Amplex Red. Th...				Biochemistry 52: 9187-201 (2013) Article DOI: 10.1021/bi401354d BindingDB Entry DOI: 10.7270/Q2K35SBT
Pfizer Worldwide Research and Development					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM119873 (3‐[(2R)‐2‐ethoxypropyl]‐2&...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	546	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Worldwide Research and Development					Assay Description Assay mixtures (100 µL) contained 50 mM NaPi (pH 7.4), 150 mM NaCl, 1 mM DTPA, 2% DMSO, the indicated concentrations of H2O2, and Amplex Red. Th...				Biochemistry 52: 9187-201 (2013) Article DOI: 10.1021/bi401354d BindingDB Entry DOI: 10.7270/Q2K35SBT
Pfizer Worldwide Research and Development					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Homo sapiens (Human))	BDBM75707 ((3R)-3-cyclopentyl-4-keto-3-phenyl-diazetidine-1,2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in human MDA-MB-231 cells after 30 mins by fluorescence polarization activity-based protein profiling assa...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400986 (CHEMBL1550905) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Homo sapiens (Human))	BDBM50400986 (CHEMBL1550905) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in human HEK293T cells after 45 mins by fluorescence polarization activity-based protein profiling assay				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400987 (CHEMBL1316687) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154536 (2-(4-tert-butylphenyl)-1-(4-methylbenzenesulfonyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154531 (2-(4-bromophenyl)-6-(4-chlorophenyl)-1-(4-methylbe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154529 (2-(4-fluorophenyl)-1-(4-methylbenzenesulfonyl)-6-[...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154534 (2-(4-bromophenyl)-6-(3,4-dichlorophenyl)-1-(4-meth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154540 (2-(4-(tert-butyl)phenyl)-N-(2-methoxyethyl)-6-(p-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154535 (2-(4-fluorophenyl)-1-(4-methylbenzenesulfonyl)-6-(...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400996 (CHEMBL1699083) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400995 (CHEMBL1706554) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400994 (CHEMBL1719837) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400988 (CHEMBL1701914) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Homo sapiens (Human))	BDBM50400986 (CHEMBL1550905) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in HEK293T cells after 1 hr by fluorescence polarization activity-based protein profiling assay				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400993 (CHEMBL1729870) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154530 (1-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)-6-[...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154542 (5-(bromomethyl)-6-(4-(tert-butyl)phenyl)-2-(p-toly...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400989 (CHEMBL1718102) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400991 (CHEMBL1711185) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154541 (N-allyl-2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tos...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154543 (N-((2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tosyl-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154533 (2-(3-chlorophenyl)-1-(4-methylbenzenesulfonyl)-6-(...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154538 (2-(4-(tert-butyl)phenyl)-N-cyclopropyl-6-(p-tolyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154532 (2-(3-chlorophenyl)-6-(4-ethylphenyl)-1-(4-methylbe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154537 (2-(4-(tert-butyl)phenyl)-N-methyl-6-(p-tolyl)-1-to...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154544 (Methyl-2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tosy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154539 (2-(4-(tert-butyl)phenyl)-N-cyclohexyl-6-(p-tolyl)-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
University of California, Berkeley					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Homo sapiens (Human))	BDBM50400997 (CHEMBL1521288) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in human MDA-MB-231 cells after 30 mins by fluorescence polarization activity-based protein profiling assa...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400990 (CHEMBL1723004) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase methylesterase 1 (Mus musculus)	BDBM50400992 (CHEMBL1701983) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...				J Med Chem 54: 5229-36 (2011) Article DOI: 10.1021/jm200502u BindingDB Entry DOI: 10.7270/Q2GX4CR6
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair