Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392802 (7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392796 (5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392796 (5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392744 (7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-5-(hexahydro...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392802 (7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecium E1679) | BDBM392794 (5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392769 (1′-Cyclohexyl-6-[methyl-(2-pyrrolidin-1-yl-e...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecium E1679) | BDBM392802 (7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392795 (7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392795 (7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392774 (US10301305, Example 136 | rac-1′-((trans)-3-...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392785 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392801 (7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392785 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392793 (7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392779 (1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392774 (US10301305, Example 136 | rac-1′-((trans)-3-...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecium E1679) | BDBM392796 (5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392793 (7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392801 (7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392781 (1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392786 (6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392794 (5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392767 (6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392789 (7-(1-butylbenzimidazol-5-yl)-5-[2-(dimethylamino)e...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392778 (1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392767 (6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392786 (6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392797 (7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[3-...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392784 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[me...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392791 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidoglycan D,D-transpeptidase MrdA (Escherichia coli) | BDBM50512952 (CHEMBL4560540) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Mutabilis Curated by ChEMBL | Assay Description Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr... | J Med Chem 62: 4742-4754 (2019) Article DOI: 10.1021/acs.jmedchem.9b00338 BindingDB Entry DOI: 10.7270/Q2CZ3BG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392742 (US10301305, Example 6 | {1-[7-(1-Cyclohexyl-1H-ben...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392746 (US10301305, Example 20 | {1-[4-(1-Cyclohexyl-1H-be...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392790 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392778 (1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392777 (6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392779 (1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392781 (1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392775 (1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392765 (1′-Cyclohexyl-6-[(2-hydroxy-ethyl)-methyl-am...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392777 (6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392775 (1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392790 (5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392776 (7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Putative glyoxylate/hydroxypyruvate reductase B (Staphylococcus aureus (strain SA113)) | BDBM392773 (6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidoglycan D,D-transpeptidase MrdA (Escherichia coli) | BDBM50512949 (CHEMBL4470489) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Mutabilis Curated by ChEMBL | Assay Description Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr... | J Med Chem 62: 4742-4754 (2019) Article DOI: 10.1021/acs.jmedchem.9b00338 BindingDB Entry DOI: 10.7270/Q2CZ3BG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392763 (1′-Cyclohexyl-6-(4-methyl-piperazin-1-yl)-1H...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392742 (US10301305, Example 6 | {1-[7-(1-Cyclohexyl-1H-ben...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanine--D-alanyl carrier protein ligase (Enterococcus faecalis (strain ATCC 700802 / V583)) | BDBM392738 ((3R,4R)-1-[7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-3...) | MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
GSK | Assay Description The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi... | Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2R213Q5 | |||||||||||
More data for this Ligand-Target Pair |
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