Compile Data Set for Download or QSAR

Found 106 hits with Last Name = 'wright' and Initial = 'cd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1/2 (RAT)	BDBM22971 (2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl Show InChI InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1/2 (RAT)	BDBM22971 (2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl Show InChI InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat posterior cortex by [3H]-BRL 43694 displacement.				Bioorg Med Chem Lett 2: 705-708 (1992) Article DOI: 10.1016/S0960-894X(00)80396-0 BindingDB Entry DOI: 10.7270/Q26H4HBV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044077 (2-Hydroxy-5-[1-(2'-hydroxy-[1,1';3',1'']terphenyl-...) Show SMILES Oc1c(cc(\C=C2/SC(=O)NC2=O)cc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H15NO3S/c24-20-17(15-7-3-1-4-8-15)11-14(13-19-21(25)23-22(26)27-19)12-18(20)16-9-5-2-6-10-16/h1-13,24H,(H,23,25,26)/b19-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044067 (5-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-1-meth...) Show SMILES CN1C(=S)NC(=O)\C1=C\c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C19H26N2O2S/c1-18(2,3)12-8-11(9-13(15(12)22)19(4,5)6)10-14-16(23)20-17(24)21(14)7/h8-10,22H,1-7H3,(H,20,23,24)/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044078 (2-Hydroxy-5-[1-(4-hydroxy-3,5-diisopropyl-phenyl)-...) Show SMILES CC(C)c1cc(\C=C2/SC(=O)NC2=O)cc(C(C)C)c1O Show InChI InChI=1S/C16H19NO3S/c1-8(2)11-5-10(6-12(9(3)4)14(11)18)7-13-15(19)17-16(20)21-13/h5-9,18H,1-4H3,(H,17,19,20)/b13-7-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50048006 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(NC#N)o2)c1Cl Show InChI InChI=1S/C16H11Cl2N5O/c1-9-6-7-11(17)14(13(9)18)21-12-5-3-2-4-10(12)15-22-23-16(24-15)20-8-19/h2-7,21H,1H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50048004 (5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...) Show SMILES FC(F)(F)c1cccc(Nc2ccccc2-c2nnc(S)o2)c1 Show InChI InChI=1S/C15H10F3N3OS/c16-15(17,18)9-4-3-5-10(8-9)19-12-7-2-1-6-11(12)13-20-21-14(23)22-13/h1-8,19H,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50047999 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(NC#N)s2)c1Cl Show InChI InChI=1S/C16H11Cl2N5S/c1-9-6-7-11(17)14(13(9)18)21-12-5-3-2-4-10(12)15-22-23-16(24-15)20-8-19/h2-7,21H,1H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280281 (CHEMBL42593 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2-...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CN(O)C(N)=O)c2c1 Show InChI InChI=1S/C19H18ClN3O4/c1-11-16(10-22(26)19(21)25)15-9-14(27-2)7-8-17(15)23(11)18(24)12-3-5-13(20)6-4-12/h3-9,26H,10H2,1-2H3,(H2,21,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044065 (5-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-2-thio...) Show SMILES CC(C)(C)c1cc(\C=C2/SC(=S)NC2=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H23NO2S2/c1-17(2,3)11-7-10(8-12(14(11)20)18(4,5)6)9-13-15(21)19-16(22)23-13/h7-9,20H,1-6H3,(H,19,21,22)/b13-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Intercellular adhesion molecule 1 (Homo sapiens (Human))	BDBM50029632 (3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...) Show SMILES COc1ccc2sc(C(N)=O)c(OC(C)C)c2c1 Show InChI InChI=1S/C13H15NO3S/c1-7(2)17-11-9-6-8(16-3)4-5-10(9)18-12(11)13(14)15/h4-7H,1-3H3,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for inhibition of ICAM expression by ELISA at the dose of 30 uM				J Med Chem 37: 717-8 (1994) BindingDB Entry DOI: 10.7270/Q2H99481
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280280 (CHEMBL295243 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2...) Show SMILES CNC(=S)N(O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 Show InChI InChI=1S/C20H20ClN3O3S/c1-12-17(11-23(26)20(28)22-2)16-10-15(27-3)8-9-18(16)24(12)19(25)13-4-6-14(21)7-5-13/h4-10,26H,11H2,1-3H3,(H,22,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044064 (5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-eth-(Z)-...) Show SMILES C\C(=C1\SC(=O)NC1=O)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C19H25NO3S/c1-10(15-16(22)20-17(23)24-15)11-8-12(18(2,3)4)14(21)13(9-11)19(5,6)7/h8-9,21H,1-7H3,(H,20,22,23)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1/2 (RAT)	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit dog plasma renin by 50% using radio-immunoassay was determined				Bioorg Med Chem Lett 2: 705-708 (1992) Article DOI: 10.1016/S0960-894X(00)80396-0 BindingDB Entry DOI: 10.7270/Q26H4HBV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50230757 (CHEMBL301586) Show SMILES FC(F)(F)c1cccc(Nc2ccccc2-c2n[nH]c(S)n2)c1 Show InChI InChI=1S/C15H11F3N4S/c16-15(17,18)9-4-3-5-10(8-9)19-12-7-2-1-6-11(12)13-20-14(23)22-21-13/h1-8,19H,(H2,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50008954 (3-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-1-meth...) Show SMILES CON1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)C1=O Show InChI InChI=1S/C20H29NO3/c1-19(2,3)15-11-13(12-16(17(15)22)20(4,5)6)10-14-8-9-21(24-7)18(14)23/h10-12,22H,8-9H2,1-7H3/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280282 (CHEMBL295008 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2...) Show SMILES CNC(=S)N(O)C(C)c1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 Show InChI InChI=1S/C21H22ClN3O3S/c1-12-19(13(2)25(27)21(29)23-3)17-11-16(28-4)9-10-18(17)24(12)20(26)14-5-7-15(22)8-6-14/h5-11,13,27H,1-4H3,(H,23,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50048003 (5-[2-(2,3-Dimethyl-phenylamino)-phenyl]-3H-[1,3,4]...) Show SMILES Cc1cccc(Nc2ccccc2-c2nnc(S)o2)c1C Show InChI InChI=1S/C16H15N3OS/c1-10-6-5-9-13(11(10)2)17-14-8-4-3-7-12(14)15-18-19-16(21)20-15/h3-9,17H,1-2H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044079 (5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...) Show SMILES CC(C)(C)c1cc(C=C2SC(NC#N)=NC2=O)cc(c1O)C(C)(C)C |w:7.6,c:13| Show InChI InChI=1S/C19H23N3O2S/c1-18(2,3)12-7-11(8-13(15(12)23)19(4,5)6)9-14-16(24)22-17(25-14)21-10-20/h7-9,23H,1-6H3,(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044076 (5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...) Show SMILES CSC1=NC(=O)\C(S1)=C\c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C |t:2| Show InChI InChI=1S/C19H25NO2S2/c1-18(2,3)12-8-11(9-13(15(12)21)19(4,5)6)10-14-16(22)20-17(23-7)24-14/h8-10,21H,1-7H3/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048010 (5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...) Show SMILES Nc1nnc(o1)-c1ccccc1Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N4O/c16-15(17,18)9-4-3-5-10(8-9)20-12-7-2-1-6-11(12)13-21-22-14(19)23-13/h1-8,20H,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048000 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(N)s2)c1Cl Show InChI InChI=1S/C15H12Cl2N4S/c1-8-6-7-10(16)13(12(8)17)19-11-5-3-2-4-9(11)14-20-21-15(18)22-14/h2-7,19H,1H3,(H2,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048005 (5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...) Show SMILES Nc1nnc(s1)-c1ccccc1Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N4S/c16-15(17,18)9-4-3-5-10(8-9)20-12-7-2-1-6-11(12)13-21-22-14(19)23-13/h1-8,20H,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50048007 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(S)o2)c1Cl Show InChI InChI=1S/C15H11Cl2N3OS/c1-8-6-7-10(16)13(12(8)17)18-11-5-3-2-4-9(11)14-19-20-15(22)21-14/h2-7,18H,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
E-selectin (Homo sapiens (Human))	BDBM50029632 (3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...) Show SMILES COc1ccc2sc(C(N)=O)c(OC(C)C)c2c1 Show InChI InChI=1S/C13H15NO3S/c1-7(2)17-11-9-6-8(16-3)4-5-10(9)18-12(11)13(14)15/h4-7H,1-3H3,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for inhibition of E-selectin expression by ELISA at the dose of 30 uM				J Med Chem 37: 717-8 (1994) BindingDB Entry DOI: 10.7270/Q2H99481
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044073 (5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...) Show SMILES CN1C(NC#N)=NC(=O)C1=Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C |w:10.11,c:5| Show InChI InChI=1S/C20H26N4O2/c1-19(2,3)13-8-12(9-14(16(13)25)20(4,5)6)10-15-17(26)23-18(22-11-21)24(15)7/h8-10,25H,1-7H3,(H,22,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048007 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(S)o2)c1Cl Show InChI InChI=1S/C15H11Cl2N3OS/c1-8-6-7-10(16)13(12(8)17)18-11-5-3-2-4-9(11)14-19-20-15(22)21-14/h2-7,18H,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044080 (2-Amino-5-[1-(3,5-di-tert-butyl-4-hydroxy-phenyl)-...) Show SMILES CC(C)(C)c1cc(C=C2SC(N)=NC2=O)cc(c1O)C(C)(C)C |w:7.6,c:11| Show InChI InChI=1S/C18H24N2O2S/c1-17(2,3)11-7-10(8-12(14(11)21)18(4,5)6)9-13-15(22)20-16(19)23-13/h7-9,21H,1-6H3,(H2,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048004 (5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...) Show SMILES FC(F)(F)c1cccc(Nc2ccccc2-c2nnc(S)o2)c1 Show InChI InChI=1S/C15H10F3N3OS/c16-15(17,18)9-4-3-5-10(8-9)19-12-7-2-1-6-11(12)13-20-21-14(23)22-13/h1-8,19H,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044063 (5-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-1-meth...) Show SMILES CN1C(=O)NC(=O)\C1=C\c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C19H26N2O3/c1-18(2,3)12-8-11(9-13(15(12)22)19(4,5)6)10-14-16(23)20-17(24)21(14)7/h8-10,22H,1-7H3,(H,20,23,24)/b14-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50003127 (CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...) Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nnc(S)s1 Show InChI InChI=1S/C16H22N2OS2/c1-15(2,3)10-7-9(13-17-18-14(20)21-13)8-11(12(10)19)16(4,5)6/h7-8,19H,1-6H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cells				Bioorg Med Chem Lett 3: 2827-2830 (1993) Article DOI: 10.1016/S0960-894X(01)80773-3 BindingDB Entry DOI: 10.7270/Q2668D4B
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280512 (5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C=C2SC(S)=NC2=O)c1Cl |w:14.14,c:19| Show InChI InChI=1S/C17H12Cl2N2OS2/c1-9-6-7-11(18)15(14(9)19)20-12-5-3-2-4-10(12)8-13-16(22)21-17(23)24-13/h2-8,20H,1H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase)				Bioorg Med Chem Lett 2: 705-708 (1992) Article DOI: 10.1016/S0960-894X(00)80396-0 BindingDB Entry DOI: 10.7270/Q26H4HBV
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280284 (CHEMBL296543 | N-{1-[1-(4-Chloro-benzoyl)-5-methox...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(C(C)N(O)C(C)=O)c2c1 Show InChI InChI=1S/C21H21ClN2O4/c1-12-20(13(2)24(27)14(3)25)18-11-17(28-4)9-10-19(18)23(12)21(26)15-5-7-16(22)8-6-15/h5-11,13,27H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044061 (5-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-2-thio...) Show SMILES CC(C)(C)c1cc(\C=C2/OC(=S)NC2=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H23NO3S/c1-17(2,3)11-7-10(8-12(14(11)20)18(4,5)6)9-13-15(21)19-16(23)22-13/h7-9,20H,1-6H3,(H,19,21,23)/b13-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50047998 (5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...) Show SMILES FC(F)(F)c1cccc(Nc2ccccc2-c2nnc(S)s2)c1 Show InChI InChI=1S/C15H10F3N3S2/c16-15(17,18)9-4-3-5-10(8-9)19-12-7-2-1-6-11(12)13-20-21-14(22)23-13/h1-8,19H,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50047998 (5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...) Show SMILES FC(F)(F)c1cccc(Nc2ccccc2-c2nnc(S)s2)c1 Show InChI InChI=1S/C15H10F3N3S2/c16-15(17,18)9-4-3-5-10(8-9)19-12-7-2-1-6-11(12)13-20-21-14(22)23-13/h1-8,19H,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048006 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(NC#N)o2)c1Cl Show InChI InChI=1S/C16H11Cl2N5O/c1-9-6-7-11(17)14(13(9)18)21-12-5-3-2-4-10(12)15-22-23-16(24-15)20-8-19/h2-7,21H,1H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50280279 (CHEMBL410500 | N-{1-[1-(4-chlorobenzoyl)-5-methoxy...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(C(C)N(O)C(N)=O)c2c1 Show InChI InChI=1S/C20H20ClN3O4/c1-11-18(12(2)24(27)20(22)26)16-10-15(28-3)8-9-17(16)23(11)19(25)13-4-6-14(21)7-5-13/h4-10,12,27H,1-3H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044072 (CHEMBL16434 | N-[5-(3,5-Di-tert-butyl-4-hydroxy-be...) Show SMILES CC(C)(C)c1cc(C=C2SC(NC(N)=N)=NC2=O)cc(c1O)C(C)(C)C |w:7.6,c:14| Show InChI InChI=1S/C19H26N4O2S/c1-18(2,3)11-7-10(8-12(14(11)24)19(4,5)6)9-13-15(25)22-17(26-13)23-16(20)21/h7-9,24H,1-6H3,(H4,20,21,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50048008 (5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...) Show SMILES FC(F)(F)c1cccc(Nc2ccccc2-c2nnc(NC#N)o2)c1 Show InChI InChI=1S/C16H10F3N5O/c17-16(18,19)10-4-3-5-11(8-10)22-13-7-2-1-6-12(13)14-23-24-15(25-14)21-9-20/h1-8,22H,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048003 (5-[2-(2,3-Dimethyl-phenylamino)-phenyl]-3H-[1,3,4]...) Show SMILES Cc1cccc(Nc2ccccc2-c2nnc(S)o2)c1C Show InChI InChI=1S/C16H15N3OS/c1-10-6-5-9-13(11(10)2)17-14-8-4-3-7-12(14)15-18-19-16(21)20-15/h3-9,17H,1-2H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50281314 (5-(3,5-Di-tert-butyl-4-hydroxy-phenylsulfanyl)-[1,...) Show SMILES CC(C)(C)c1cc(Sc2n[nH]c(=O)o2)cc(c1O)C(C)(C)C Show InChI InChI=1S/C16H22N2O3S/c1-15(2,3)10-7-9(22-14-18-17-13(20)21-14)8-11(12(10)19)16(4,5)6/h7-8,19H,1-6H3,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cells				Bioorg Med Chem Lett 3: 2827-2830 (1993) Article DOI: 10.1016/S0960-894X(01)80773-3 BindingDB Entry DOI: 10.7270/Q2668D4B
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50281316 (2,6-Di-tert-butyl-4-(5-mercapto-[1,3,4]thiadiazol-...) Show SMILES CC(C)(C)c1cc(Sc2nnc(S)s2)cc(c1O)C(C)(C)C Show InChI InChI=1S/C16H22N2OS3/c1-15(2,3)10-7-9(21-14-18-17-13(20)22-14)8-11(12(10)19)16(4,5)6/h7-8,19H,1-6H3,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cells				Bioorg Med Chem Lett 3: 2827-2830 (1993) Article DOI: 10.1016/S0960-894X(01)80773-3 BindingDB Entry DOI: 10.7270/Q2668D4B
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50012893 (2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NO)c2c1 Show InChI InChI=1S/C19H17ClN2O4/c1-11-15(10-18(23)21-25)16-9-14(26-2)7-8-17(16)22(11)19(24)12-3-5-13(20)6-4-12/h3-9,25H,10H2,1-2H3,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)				Bioorg Med Chem Lett 2: 1655-1660 (1992) Article DOI: 10.1016/S0960-894X(00)80450-3 BindingDB Entry DOI: 10.7270/Q2TD9X9T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044074 (CHEMBL113138 | CHEMBL15781 | N-{5-[1-(3,5-Di-tert-...) Show SMILES CC(C)(C)c1cc(C=C2OC(NC(N)=N)=NC2=O)cc(c1O)C(C)(C)C |w:7.6,c:14| Show InChI InChI=1S/C19H26N4O3/c1-18(2,3)11-7-10(8-12(14(11)24)19(4,5)6)9-13-15(25)22-17(26-13)23-16(20)21/h7-9,24H,1-6H3,(H4,20,21,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044062 (5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-eth-(Z)-...) Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=C)c1sc(NC#N)nc1O Show InChI InChI=1S/C20H25N3O2S/c1-11(16-17(25)23-18(26-16)22-10-21)12-8-13(19(2,3)4)15(24)14(9-12)20(5,6)7/h8-9,24-25H,1H2,2-7H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044068 (CHEMBL15904 | N-[5-(3,5-Di-tert-butyl-4-hydroxy-be...) Show SMILES CN1C(NC(N)=N)=NC(=O)C1=Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C |w:11.12,c:6| Show InChI InChI=1S/C20H29N5O2/c1-19(2,3)12-8-11(9-13(15(12)26)20(4,5)6)10-14-16(27)23-18(25(14)7)24-17(21)22/h8-10,26H,1-7H3,(H4,21,22,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair
E-selectin (Homo sapiens (Human))	BDBM50029631 (3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...) Show SMILES CNC(=O)c1sc2ccc(OC)cc2c1OC(C)C Show InChI InChI=1S/C14H17NO3S/c1-8(2)18-12-10-7-9(17-4)5-6-11(10)19-13(12)14(16)15-3/h5-8H,1-4H3,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for inhibition of E-selectin expression by ELISA at the dose of 30 uM				J Med Chem 37: 717-8 (1994) BindingDB Entry DOI: 10.7270/Q2H99481
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50044059 (5-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-thiazo...) Show SMILES CC(C)(C)c1cc(\C=C2/SC(=O)NC2=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H23NO3S/c1-17(2,3)11-7-10(8-12(14(11)20)18(4,5)6)9-13-15(21)19-16(22)23-13/h7-9,20H,1-6H3,(H,19,21,22)/b13-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187				J Med Chem 37: 322-8 (1994) BindingDB Entry DOI: 10.7270/Q28C9V9P
					More data for this Ligand-Target Pair

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