Compile Data Set for Download or QSAR

Found 43 hits with Last Name = 'barker' and Initial = 'el'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES CCCN(CCC)C1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23 Show InChI InChI=1S/C19H26N2O/c1-4-8-21(9-5-2)15-10-14-12-20-18-7-6-16(13(3)22)17(11-15)19(14)18/h6-7,12,15,20H,4-5,8-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition constant of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094673 (CHEMBL342986 | Diethyl-[2-(5-methoxy-1H-indol-3-yl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(OC)cc12 Show InChI InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2c(F)ccc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)6-5-8-7-14-12-9(13)3-4-10(16)11(8)12/h3-4,7,14,16H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094671 (3-(2-Dimethylamino-ethyl)-6-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2cc(F)cc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)4-3-8-7-14-10-5-9(13)6-11(16)12(8)10/h5-7,14,16H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094675 (3-(2-Diethylamino-ethyl)-1H-indol-4-ol | CHEMBL143...) Show SMILES CCN(CC)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2c(F)ccc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)6-5-8-7-14-12-9(13)3-4-10(16)11(8)12/h3-4,7,14,16H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094673 (CHEMBL342986 | Diethyl-[2-(5-methoxy-1H-indol-3-yl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(OC)cc12 Show InChI InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094669 (CHEMBL337590 | [2-(6-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1cc2c(CCN(C)C)c[nH]c2cc1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)5-4-9-8-15-12-7-11(14)13(17-3)6-10(9)12/h6-8,15H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094675 (3-(2-Diethylamino-ethyl)-1H-indol-4-ol | CHEMBL143...) Show SMILES CCN(CC)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094669 (CHEMBL337590 | [2-(6-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1cc2c(CCN(C)C)c[nH]c2cc1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)5-4-9-8-15-12-7-11(14)13(17-3)6-10(9)12/h6-8,15H,4-5H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094673 (CHEMBL342986 | Diethyl-[2-(5-methoxy-1H-indol-3-yl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(OC)cc12 Show InChI InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094676 (CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...) Show SMILES CCN(CC)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094675 (3-(2-Diethylamino-ethyl)-1H-indol-4-ol | CHEMBL143...) Show SMILES CCN(CC)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094674 (CHEMBL142862 | [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)7-6-9-8-15-10-4-5-11(17-3)13(14)12(9)10/h4-5,8,15H,6-7H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094669 (CHEMBL337590 | [2-(6-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1cc2c(CCN(C)C)c[nH]c2cc1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)5-4-9-8-15-12-7-11(14)13(17-3)6-10(9)12/h6-8,15H,4-5H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	84.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094676 (CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...) Show SMILES CCN(CC)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094671 (3-(2-Dimethylamino-ethyl)-6-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2cc(F)cc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)4-3-8-7-14-10-5-9(13)6-11(16)12(8)10/h5-7,14,16H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2c(F)ccc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)6-5-8-7-14-12-9(13)3-4-10(16)11(8)12/h3-4,7,14,16H,5-6H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094674 (CHEMBL142862 | [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)7-6-9-8-15-10-4-5-11(17-3)13(14)12(9)10/h4-5,8,15H,6-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094676 (CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...) Show SMILES CCN(CC)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094672 (CHEMBL444612 | Diethyl-[2-(6-fluoro-1H-indol-3-yl)...) Show SMILES CCN(CC)CCc1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H19FN2/c1-3-17(4-2)8-7-11-10-16-14-9-12(15)5-6-13(11)14/h5-6,9-10,16H,3-4,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094672 (CHEMBL444612 | Diethyl-[2-(6-fluoro-1H-indol-3-yl)...) Show SMILES CCN(CC)CCc1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H19FN2/c1-3-17(4-2)8-7-11-10-16-14-9-12(15)5-6-13(11)14/h5-6,9-10,16H,3-4,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094672 (CHEMBL444612 | Diethyl-[2-(6-fluoro-1H-indol-3-yl)...) Show SMILES CCN(CC)CCc1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H19FN2/c1-3-17(4-2)8-7-11-10-16-14-9-12(15)5-6-13(11)14/h5-6,9-10,16H,3-4,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM81945 (CAS_39484 | CHEMBL105891 | CHEMBL108926 | CHEMBL27...) Show SMILES C[n+]1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C12H12N/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-10H,1H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at human SERT C109A mutant transfected in HEK cells				Bioorg Med Chem 15: 305-11 (2007) Article DOI: 10.1016/j.bmc.2006.09.058 BindingDB Entry DOI: 10.7270/Q2DV1NNQ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50476261 (4-(1-Methylpyridinium)Phenylmethanethiosulphonate ...) Show SMILES [I-].C[n+]1ccc(cc1)-c1ccc(SS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H14NO2S2/c1-14-9-7-12(8-10-14)11-3-5-13(6-4-11)17-18(2,15)16/h3-10H,1-2H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at human SERT C109A mutant transfected in HEK cells				Bioorg Med Chem 15: 305-11 (2007) Article DOI: 10.1016/j.bmc.2006.09.058 BindingDB Entry DOI: 10.7270/Q2DV1NNQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094677 (3-(2-Dimethylamino-ethyl)-7-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2c(F)ccc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)6-5-8-7-14-12-9(13)3-4-10(16)11(8)12/h3-4,7,14,16H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.92E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094676 (CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...) Show SMILES CCN(CC)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.37E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094676 (CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...) Show SMILES CCN(CC)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	680	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094672 (CHEMBL444612 | Diethyl-[2-(6-fluoro-1H-indol-3-yl)...) Show SMILES CCN(CC)CCc1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H19FN2/c1-3-17(4-2)8-7-11-10-16-14-9-12(15)5-6-13(11)14/h5-6,9-10,16H,3-4,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094673 (CHEMBL342986 | Diethyl-[2-(5-methoxy-1H-indol-3-yl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(OC)cc12 Show InChI InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094671 (3-(2-Dimethylamino-ethyl)-6-fluoro-1H-indol-4-ol |...) Show SMILES CN(C)CCc1c[nH]c2cc(F)cc(O)c12 Show InChI InChI=1S/C12H15FN2O/c1-15(2)4-3-8-7-14-10-5-9(13)6-11(16)12(8)10/h5-7,14,16H,3-4H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094669 (CHEMBL337590 | [2-(6-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1cc2c(CCN(C)C)c[nH]c2cc1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)5-4-9-8-15-12-7-11(14)13(17-3)6-10(9)12/h6-8,15H,4-5H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094674 (CHEMBL142862 | [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)7-6-9-8-15-10-4-5-11(17-3)13(14)12(9)10/h4-5,8,15H,6-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094672 (CHEMBL444612 | Diethyl-[2-(6-fluoro-1H-indol-3-yl)...) Show SMILES CCN(CC)CCc1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H19FN2/c1-3-17(4-2)8-7-11-10-16-14-9-12(15)5-6-13(11)14/h5-6,9-10,16H,3-4,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.82	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094675 (3-(2-Diethylamino-ethyl)-1H-indol-4-ol | CHEMBL143...) Show SMILES CCN(CC)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50476261 (4-(1-Methylpyridinium)Phenylmethanethiosulphonate ...) Show SMILES [I-].C[n+]1ccc(cc1)-c1ccc(SS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H14NO2S2/c1-14-9-7-12(8-10-14)11-3-5-13(6-4-11)17-18(2,15)16/h3-10H,1-2H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.16E+13	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Decrease in [3H]5-HT uptake at human SERT W103C mutant transfected in HEK293 cells				Bioorg Med Chem 15: 305-11 (2007) Article DOI: 10.1016/j.bmc.2006.09.058 BindingDB Entry DOI: 10.7270/Q2DV1NNQ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50476262 (CHEMBL224476) Show SMILES C[N+](C)(C)CCSS(C)(=O)=O Show InChI InChI=1S/C6H16NO2S2/c1-7(2,3)5-6-10-11(4,8)9/h5-6H2,1-4H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Decrease in [3H]5-HT uptake at human SERT G498C mutant transfected in HEK293 cells				Bioorg Med Chem 15: 305-11 (2007) Article DOI: 10.1016/j.bmc.2006.09.058 BindingDB Entry DOI: 10.7270/Q2DV1NNQ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50476262 (CHEMBL224476) Show SMILES C[N+](C)(C)CCSS(C)(=O)=O Show InChI InChI=1S/C6H16NO2S2/c1-7(2,3)5-6-10-11(4,8)9/h5-6H2,1-4H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+12	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Decrease in [3H]5-HT uptake at human SERT W103C mutant transfected in HEK293 cells				Bioorg Med Chem 15: 305-11 (2007) Article DOI: 10.1016/j.bmc.2006.09.058 BindingDB Entry DOI: 10.7270/Q2DV1NNQ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50476261 (4-(1-Methylpyridinium)Phenylmethanethiosulphonate ...) Show SMILES [I-].C[n+]1ccc(cc1)-c1ccc(SS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H14NO2S2/c1-14-9-7-12(8-10-14)11-3-5-13(6-4-11)17-18(2,15)16/h3-10H,1-2H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Decrease in [3H]5-HT uptake at human SERT G498C mutant transfected in HEK293 cells				Bioorg Med Chem 15: 305-11 (2007) Article DOI: 10.1016/j.bmc.2006.09.058 BindingDB Entry DOI: 10.7270/Q2DV1NNQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES CCCN(CCC)C1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23 Show InChI InChI=1S/C19H26N2O/c1-4-8-21(9-5-2)15-10-14-12-20-18-7-6-16(13(3)22)17(11-15)19(14)18/h6-7,12,15,20H,4-5,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094673 (CHEMBL342986 | Diethyl-[2-(5-methoxy-1H-indol-3-yl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(OC)cc12 Show InChI InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094674 (CHEMBL142862 | [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)7-6-9-8-15-10-4-5-11(17-3)13(14)12(9)10/h4-5,8,15H,6-7H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.930	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair