Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50197001![]() (CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50197003![]() (CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50197002![]() (CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50197000![]() (CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50197004![]() (3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50196999![]() (CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21.6 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50197005![]() (CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 44.9 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETA receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 3 (Homo sapiens (Human)) | BDBM50557651![]() (CHEMBL4761535) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in absence of extracellular calcium by whole cel... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00571 BindingDB Entry DOI: 10.7270/Q2V69P8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 3 (Homo sapiens (Human)) | BDBM50557651![]() (CHEMBL4761535) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in presence of 2 mM extracellular calcium by who... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00571 BindingDB Entry DOI: 10.7270/Q2V69P8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 3 (Homo sapiens (Human)) | BDBM50450629![]() (CHEMBL4177187) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in presence of 2 mM extracellular calcium by who... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00571 BindingDB Entry DOI: 10.7270/Q2V69P8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 3 (Homo sapiens (Human)) | BDBM50450629![]() (CHEMBL4177187) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in absence of extracellular calcium by whole cel... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00571 BindingDB Entry DOI: 10.7270/Q2V69P8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 3 (Mus musculus) | BDBM50450629![]() (CHEMBL4177187) | PDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse TRPC3 expressed in HEK293 cells assessed as inhibition of Ca2+ influx by whole cell patch-clamp method | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00571 BindingDB Entry DOI: 10.7270/Q2V69P8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50197003![]() (CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50197002![]() (CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50197000![]() (CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50197004![]() (3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50196999![]() (CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50197001![]() (CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50197005![]() (CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CovX Research LLC Curated by ChEMBL | Assay Description Displacement of [125I]ET1 from human ETB receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 501-6 (2007) Article DOI: 10.1016/j.bmcl.2006.10.009 BindingDB Entry DOI: 10.7270/Q2DZ07ZF | |||||||||||
More data for this Ligand-Target Pair |