Found 185 hits with Last Name = 'kumagai' and Initial = 'h' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | Reactome pathway
UniProtKB/SwissProt
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| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115122
(CHEMBL3609360)Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CCCN2CCc3ccccc3C2)CC1 Show InChI InChI=1S/C25H30FN3/c26-22-6-7-23-24(17-27-25(23)16-22)20-9-13-28(14-10-20)11-3-12-29-15-8-19-4-1-2-5-21(19)18-29/h1-2,4-7,16-17,20,27H,3,8-15,18H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187753
(6-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-19-20(16-23-21(19)15-18)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187752
(3-(1-(4-(piperidin-1-yl)butyl)piperidin-4-yl)-1H-i...)Show InChI InChI=1S/C22H33N3/c1-4-12-24(13-5-1)14-6-7-15-25-16-10-19(11-17-25)21-18-23-22-9-3-2-8-20(21)22/h2-3,8-9,18-19,23H,1,4-7,10-17H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187747
(3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115121
(CHEMBL3609359)Show SMILES C(CN1CCC(CC1)c1c[nH]c2ccccc12)CN1CCc2ccccc2C1 Show InChI InChI=1S/C25H31N3/c1-2-7-22-19-28(17-10-20(22)6-1)14-5-13-27-15-11-21(12-16-27)24-18-26-25-9-4-3-8-23(24)25/h1-4,6-9,18,21,26H,5,10-17,19H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115118
(CHEMBL3609357)Show SMILES C(CN1Cc2ccccc2C1)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-2-7-21-18-27(17-20(21)6-1)13-5-12-26-14-10-19(11-15-26)23-16-25-24-9-4-3-8-22(23)24/h1-4,6-9,16,19,25H,5,10-15,17-18H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115188
(CHEMBL3609353)Show InChI InChI=1S/C18H27N3/c1-20(2)10-5-11-21-12-8-15(9-13-21)17-14-19-18-7-4-3-6-16(17)18/h3-4,6-7,14-15,19H,5,8-13H2,1-2H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115120
(CHEMBL3609358)Show SMILES C(CN1CCC(CC1)c1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C27H35N3/c1-2-7-22(8-3-1)23-11-17-29(18-12-23)15-6-16-30-19-13-24(14-20-30)26-21-28-27-10-5-4-9-25(26)27/h1-5,7-10,21,23-24,28H,6,11-20H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115123
(CHEMBL3609354)Show SMILES O=C1N(CCCN2CCC(CC2)c2c[nH]c3ccccc23)C(=O)c2ccccc12 Show InChI InChI=1S/C24H25N3O2/c28-23-19-7-1-2-8-20(19)24(29)27(23)13-5-12-26-14-10-17(11-15-26)21-16-25-22-9-4-3-6-18(21)22/h1-4,6-9,16-17,25H,5,10-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115114
(CHEMBL3609356)Show SMILES C(CN1CCc2ccccc12)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-4-9-24-20(6-1)12-17-27(24)14-5-13-26-15-10-19(11-16-26)22-18-25-23-8-3-2-7-21(22)23/h1-4,6-9,18-19,25H,5,10-17H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187757
(1-(3-(4-(benzofuran-3-yl)piperidin-1-yl)propyl)pip...)Show InChI InChI=1S/C21H30N2O/c1-4-11-22(12-5-1)13-6-14-23-15-9-18(10-16-23)20-17-24-21-8-3-2-7-19(20)21/h2-3,7-8,17-18H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115113
(CHEMBL3609355)Show InChI InChI=1S/C20H25N3/c1-2-7-20-18(6-1)19(16-21-20)17-8-14-23(15-9-17)13-5-12-22-10-3-4-11-22/h1-4,6-7,10-11,16-17,21H,5,8-9,12-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115190
(CHEMBL3609351)Show InChI InChI=1S/C22H26N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h1-5,7-8,10-11,17,19,23H,6,9,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187754
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)benz...)Show InChI InChI=1S/C20H29N3O/c1-4-11-22(12-5-1)13-6-14-23-15-9-17(10-16-23)20-18-7-2-3-8-19(18)24-21-20/h2-3,7-8,17H,1,4-6,9-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50115122
(CHEMBL3609360)Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CCCN2CCc3ccccc3C2)CC1 Show InChI InChI=1S/C25H30FN3/c26-22-6-7-23-24(17-27-25(23)16-22)20-9-13-28(14-10-20)11-3-12-29-15-8-19-4-1-2-5-21(19)18-29/h1-2,4-7,16-17,20,27H,3,8-15,18H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant alpha1D adrenoceptor |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187748
(5-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-21-19(15-18)20(16-23-21)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115190
(CHEMBL3609351)Show InChI InChI=1S/C22H26N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h1-5,7-8,10-11,17,19,23H,6,9,12-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187753
(6-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-19-20(16-23-21(19)15-18)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50187753
(6-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-19-20(16-23-21(19)15-18)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human adrenergic Alpha-1D receptor |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115122
(CHEMBL3609360)Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CCCN2CCc3ccccc3C2)CC1 Show InChI InChI=1S/C25H30FN3/c26-22-6-7-23-24(17-27-25(23)16-22)20-9-13-28(14-10-20)11-3-12-29-15-8-19-4-1-2-5-21(19)18-29/h1-2,4-7,16-17,20,27H,3,8-15,18H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50187747
(3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human adrenergic Alpha-1D receptor |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50115189
(CHEMBL3609352)Show InChI InChI=1S/C22H32N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h4-5,10-11,17-19,23H,1-3,6-9,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115118
(CHEMBL3609357)Show SMILES C(CN1Cc2ccccc2C1)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-2-7-21-18-27(17-20(21)6-1)13-5-12-26-14-10-19(11-15-26)23-16-25-24-9-4-3-8-22(23)24/h1-4,6-9,16,19,25H,5,10-15,17-18H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115114
(CHEMBL3609356)Show SMILES C(CN1CCc2ccccc12)CN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H29N3/c1-4-9-24-20(6-1)12-17-27(24)14-5-13-26-15-10-19(11-16-26)22-18-25-23-8-3-2-7-21(22)23/h1-4,6-9,18-19,25H,5,10-17H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115123
(CHEMBL3609354)Show SMILES O=C1N(CCCN2CCC(CC2)c2c[nH]c3ccccc23)C(=O)c2ccccc12 Show InChI InChI=1S/C24H25N3O2/c28-23-19-7-1-2-8-20(19)24(29)27(23)13-5-12-26-14-10-17(11-15-26)21-16-25-22-9-4-3-6-18(21)22/h1-4,6-9,16-17,25H,5,10-15H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187752
(3-(1-(4-(piperidin-1-yl)butyl)piperidin-4-yl)-1H-i...)Show InChI InChI=1S/C22H33N3/c1-4-12-24(13-5-1)14-6-7-15-25-16-10-19(11-17-25)21-18-23-22-9-3-2-8-20(21)22/h2-3,8-9,18-19,23H,1,4-7,10-17H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187747
(3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187754
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)benz...)Show InChI InChI=1S/C20H29N3O/c1-4-11-22(12-5-1)13-6-14-23-15-9-17(10-16-23)20-18-7-2-3-8-19(18)24-21-20/h2-3,7-8,17H,1,4-6,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187757
(1-(3-(4-(benzofuran-3-yl)piperidin-1-yl)propyl)pip...)Show InChI InChI=1S/C21H30N2O/c1-4-11-22(12-5-1)13-6-14-23-15-9-18(10-16-23)20-17-24-21-8-3-2-7-19(20)21/h2-3,7-8,17-18H,1,4-6,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187750
(1-methyl-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C22H33N3/c1-23-18-21(20-8-3-4-9-22(20)23)19-10-16-25(17-11-19)15-7-14-24-12-5-2-6-13-24/h3-4,8-9,18-19H,2,5-7,10-17H2,1H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human adrenergic Alpha-1D receptor |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187756
(1-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C20H30N4O/c25-20-21-18-7-2-3-8-19(18)24(20)17-9-15-23(16-10-17)14-6-13-22-11-4-1-5-12-22/h2-3,7-8,17H,1,4-6,9-16H2,(H,21,25) | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50187751
(2-methyl-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C22H33N3/c1-18-22(20-8-3-4-9-21(20)23-18)19-10-16-25(17-11-19)15-7-14-24-12-5-2-6-13-24/h3-4,8-9,19,23H,2,5-7,10-17H2,1H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115113
(CHEMBL3609355)Show InChI InChI=1S/C20H25N3/c1-2-7-20-18(6-1)19(16-21-20)17-8-14-23(15-9-17)13-5-12-22-10-3-4-11-22/h1-4,6-7,10-11,16-17,21H,5,8-9,12-15H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187749
(3-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C21H31N3/c1-4-11-23(12-5-1)13-6-14-24-15-9-18(10-16-24)20-17-22-21-8-3-2-7-19(20)21/h2-3,7-8,17-18,22H,1,4-6,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115121
(CHEMBL3609359)Show SMILES C(CN1CCC(CC1)c1c[nH]c2ccccc12)CN1CCc2ccccc2C1 Show InChI InChI=1S/C25H31N3/c1-2-7-22-19-28(17-10-20(22)6-1)14-5-13-27-15-11-21(12-16-27)24-18-26-25-9-4-3-8-23(24)25/h1-4,6-9,18,21,26H,5,10-17,19H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM50121214
(CHEMBL3623075)Show SMILES COc1ccc(cc1S(=O)(=O)Nc1cccc(NCCNC(=O)c2cccc(C)c2)c1)-c1cccc(c1)C(=O)N(C)C Show InChI InChI=1S/C32H34N4O5S/c1-22-8-5-10-25(18-22)31(37)34-17-16-33-27-12-7-13-28(21-27)35-42(39,40)30-20-24(14-15-29(30)41-4)23-9-6-11-26(19-23)32(38)36(2)3/h5-15,18-21,33,35H,16-17H2,1-4H3,(H,34,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description Displacement of [125I]orexin-A from human OX1R expressed in CHO cell membranes by scintillation counting method |
J Med Chem 58: 7931-7 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00988 BindingDB Entry DOI: 10.7270/Q2GH9KSW |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115189
(CHEMBL3609352)Show InChI InChI=1S/C22H32N2/c1-2-7-18(8-3-1)9-6-14-24-15-12-19(13-16-24)21-17-23-22-11-5-4-10-20(21)22/h4-5,10-11,17-19,23H,1-3,6-9,12-16H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115120
(CHEMBL3609358)Show SMILES C(CN1CCC(CC1)c1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C27H35N3/c1-2-7-22(8-3-1)23-11-17-29(18-12-23)15-6-16-30-19-13-24(14-20-30)26-21-28-27-10-5-4-9-25(26)27/h1-5,7-10,21,23-24,28H,6,11-20H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50115188
(CHEMBL3609353)Show InChI InChI=1S/C18H27N3/c1-20(2)10-5-11-21-12-8-15(9-13-21)17-14-19-18-7-4-3-6-16(17)18/h3-4,6-7,14-15,19H,5,8-13H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1A adrenoceptor in rat submaxillary gland membrane |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat)) | BDBM50379819
(CHEMBL2011564)Show InChI InChI=1S/C13H16N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-4,9-10,14-15H,5-8H2 | Reactome pathway
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha1B adrenoceptor in rat liver membranes |
Bioorg Med Chem Lett 25: 3921-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.046 BindingDB Entry DOI: 10.7270/Q27M09Q4 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187750
(1-methyl-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C22H33N3/c1-23-18-21(20-8-3-4-9-22(20)23)19-10-16-25(17-11-19)15-7-14-24-12-5-2-6-13-24/h3-4,8-9,18-19H,2,5-7,10-17H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187748
(5-fluoro-3-(1-(3-(piperidin-1-yl)propyl)piperidin-...)Show InChI InChI=1S/C21H30FN3/c22-18-5-6-21-19(15-18)20(16-23-21)17-7-13-25(14-8-17)12-4-11-24-9-2-1-3-10-24/h5-6,15-17,23H,1-4,7-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM50121214
(CHEMBL3623075)Show SMILES COc1ccc(cc1S(=O)(=O)Nc1cccc(NCCNC(=O)c2cccc(C)c2)c1)-c1cccc(c1)C(=O)N(C)C Show InChI InChI=1S/C32H34N4O5S/c1-22-8-5-10-25(18-22)31(37)34-17-16-33-27-12-7-13-28(21-27)35-42(39,40)30-20-24(14-15-29(30)41-4)23-9-6-11-26(19-23)32(38)36(2)3/h5-15,18-21,33,35H,16-17H2,1-4H3,(H,34,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description Displacement of [125I]orexin-A from human OX2R expressed in HEK293 cell membranes by scintillation counting method |
J Med Chem 58: 7931-7 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00988 BindingDB Entry DOI: 10.7270/Q2GH9KSW |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50187756
(1-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)Show InChI InChI=1S/C20H30N4O/c25-20-21-18-7-2-3-8-19(18)24(20)17-9-15-23(16-10-17)14-6-13-22-11-4-1-5-12-22/h2-3,7-8,17H,1,4-6,9-16H2,(H,21,25) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes |
Bioorg Med Chem Lett 16: 4045-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001 |
More data for this Ligand-Target Pair | |