BindingDB PrimarySearch

Found 6366 hits with Last Name = 'mclean' and Initial = 'h'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194747 (((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@@H](CN)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194747 (((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@@H](CN)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50005267 (2,5-dimethoxy-4-bromophenethylamine \| 2-(4-Bromo-2...) Show SMILES COc1cc(CCN)c(OC)cc1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194752 ((+/-)-(4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)m...) Show SMILES COc1cc(Br)c(OC)c2CC(CN)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194752 ((+/-)-(4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)m...) Show SMILES COc1cc(Br)c(OC)c2CC(CN)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005267 (2,5-dimethoxy-4-bromophenethylamine \| 2-(4-Bromo-2...) Show SMILES COc1cc(CCN)c(OC)cc1Br Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2C receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194750 (((S)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@H](CN)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194750 (((S)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@H](CN)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194751 (C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine \| C...) Show SMILES COc1cc(Br)c(OC)c2CCC(CN)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194751 (C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine \| C...) Show SMILES COc1cc(Br)c(OC)c2CCC(CN)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50190613 ((+/-)-(2,3-dihydro-4,5,6-trimethoxy-1H-inden-1-yl)...) Show SMILES COc1cc2C(CN)CCc2c(OC)c1OC Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2C receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50190615 ((R)-(+)-(4,5,6-trimethoxyindan-1-yl)methanamine \| ...) Show SMILES COc1cc2[C@H](CN)CCc2c(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194749 (C-(3-bromo-5-methoxy-1,6,7,8,9,9a-hexahydro-2-oxab...) Show SMILES COc1cc(Br)c2OC[C@H]3CCC[C@H](CN)c1c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50190613 ((+/-)-(2,3-dihydro-4,5,6-trimethoxy-1H-inden-1-yl)...) Show SMILES COc1cc2C(CN)CCc2c(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194749 (C-(3-bromo-5-methoxy-1,6,7,8,9,9a-hexahydro-2-oxab...) Show SMILES COc1cc(Br)c2OC[C@H]3CCC[C@H](CN)c1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194748 (C-(3-bromo-5-methoxy-1,6,7,8,9,9a-hexahydro-2-oxab...) Show SMILES COc1cc(Br)c2OC[C@H]3CCC[C@@H](CN)c1c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194748 (C-(3-bromo-5-methoxy-1,6,7,8,9,9a-hexahydro-2-oxab...) Show SMILES COc1cc(Br)c2OC[C@H]3CCC[C@@H](CN)c1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2C receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50190614 ((S)-(-)-(4,5,6-trimethoxyindan-1-yl)methanamine \| ...) Show SMILES COc1cc2[C@@H](CN)CCc2c(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50467024 (CHEMBL4280697) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assay				Bioorg Med Chem Lett 28: 3255-3259 (2018) Article DOI: 10.1016/j.bmcl.2018.07.044 BindingDB Entry DOI: 10.7270/Q2BG2RPC
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50316768 ((Z,Z)-5-[3-Chloro-4-((2S)-2,3-dihydroxy-propoxy)-b...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assay				Bioorg Med Chem Lett 28: 3255-3259 (2018) Article DOI: 10.1016/j.bmcl.2018.07.044 BindingDB Entry DOI: 10.7270/Q2BG2RPC
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553299 (CHEMBL4790404) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553304 (CHEMBL4748743) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553297 (CHEMBL4747234) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553300 (CHEMBL4796729) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553289 (CHEMBL4763318) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50316771 ((Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-propyli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553294 (CHEMBL4759157) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553287 (CHEMBL4745979) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50164336 (2-(2-Chloro-4,6-dimethoxy-phenyl)-1-methyl-ethylam...) Show SMILES COc1cc(Cl)c(CC(C)N)c(OC)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553303 (CHEMBL4748038) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50164326 (2-(4-Ethylsulfanyl-2,6-dimethoxy-phenyl)-1-methyl-...) Show SMILES CCSc1cc(OC)c(CC(C)N)c(OC)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50164327 (2-(4-Ethylsulfanyl-phenyl)-1-methyl-ethylamine \| 2...) Show SMILES CCSc1ccc(CC(C)N)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553302 (CHEMBL4751870) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50467023 (CHEMBL4287514) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assay				Bioorg Med Chem Lett 28: 3255-3259 (2018) Article DOI: 10.1016/j.bmcl.2018.07.044 BindingDB Entry DOI: 10.7270/Q2BG2RPC
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50467022 (CHEMBL4292022) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assay				Bioorg Med Chem Lett 28: 3255-3259 (2018) Article DOI: 10.1016/j.bmcl.2018.07.044 BindingDB Entry DOI: 10.7270/Q2BG2RPC
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553288 (CHEMBL4755800) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553290 (CHEMBL4740803) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50005270 (1-(4-ethoxyphenyl)propan-2-amine \| 2-(4-Ethoxy-phe...) Show SMILES CCOc1ccc(CC(C)N)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50063544 (1-(6-(methylthio)naphthalen-2-yl)propan-2-amine \| ...) Show SMILES CSc1ccc(CC(C)N)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553295 (CHEMBL4758919) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50553293 (CHEMBL4757599) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00616 BindingDB Entry DOI: 10.7270/Q20868ZH
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50164324 (2-(2,6-Dimethoxy-4-methylsulfanyl-phenyl)-1-methyl...) Show SMILES COc1cc(SC)cc(OC)c1CC(C)N Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50164325 (CHEMBL189630 \| [2-(2,5-Dimethoxy-4-propylsulfanyl-...) Show SMILES CCCSc1cc(OC)c(CC(C)NC)cc1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine \| (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50467025 (CHEMBL4288608) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of S1PR1 (unknown origin) expressed in CHOK1 cells after 90 mins by beta-arresting recuitment assay				Bioorg Med Chem Lett 28: 3255-3259 (2018) Article DOI: 10.1016/j.bmcl.2018.07.044 BindingDB Entry DOI: 10.7270/Q2BG2RPC
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50164320 (2-(4-Isobutylsulfanyl-phenyl)-1-methyl-ethylamine ...) Show SMILES CC(C)CSc1ccc(CC(C)N)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
Universidad de Chile Curated by ChEMBL					More data for this Ligand-Target Pair

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