Compile Data Set for Download or QSAR

Found 300 hits with Last Name = 'casas' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341332 (CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(Cc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C30H34N4O7/c35-26-25(27(36)29(38)30(39)28(26)37)31-14-22-16-34(33-32-22)15-21-11-23(40-17-19-7-3-1-4-8-19)13-24(12-21)41-18-20-9-5-2-6-10-20/h1-13,16,25-31,35-39H,14-15,17-18H2/t25-,26-,27+,28+,29-,30-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341324 (CHEMBL1766482 | rel-(1R,2S,4R,5S)-6-[[1-Undecyl-1H...) Show SMILES CCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C20H38N4O5/c1-2-3-4-5-6-7-8-9-10-11-24-13-14(22-23-24)12-21-15-16(25)18(27)20(29)19(28)17(15)26/h13,15-21,25-29H,2-12H2,1H3/t15-,16-,17+,18+,19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318564 ((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318563 ((1R,2S,3r,4R,5S,6s)-6-[(1-Tetradecyl-1H-1,2,3-tria...) Show SMILES CCCCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C23H44N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-27-16-17(25-26-27)15-24-18-19(28)21(30)23(32)22(31)20(18)29/h16,18-24,28-32H,2-15H2,1H3/t18-,19-,20+,21+,22-,23-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318562 ((1R,2S,3r,4R,5S,6s)-6-[(1-Decyl-1H-1,2,3-triazol-4...) Show SMILES CCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-9-10-23-12-13(21-22-23)11-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341335 (CHEMBL1766474 | rel-(1R,2S,4R,5S)-6-[[1-(4-Cyclohe...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCCCC3CCCCC3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H34N4O5/c24-15-14(16(25)18(27)19(28)17(15)26)20-10-13-11-23(22-21-13)9-5-4-8-12-6-2-1-3-7-12/h11-12,14-20,24-28H,1-10H2/t14-,15-,16+,17+,18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM18358 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...) Show SMILES CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM18358 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...) Show SMILES CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318560 (CHEMBL1083795 | N-decylaminocyclitol) Show SMILES CCCCCCCCCCN[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H33NO5/c1-2-3-4-5-6-7-8-9-10-17-11-12(18)14(20)16(22)15(21)13(11)19/h11-22H,2-10H2,1H3/t11-,12-,13+,14+,15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318560 (CHEMBL1083795 | N-decylaminocyclitol) Show SMILES CCCCCCCCCCN[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H33NO5/c1-2-3-4-5-6-7-8-9-10-17-11-12(18)14(20)16(22)15(21)13(11)19/h11-22H,2-10H2,1H3/t11-,12-,13+,14+,15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318561 ((1R,2S,3r,4R,5S,6s)-6-[(1-Nonyl-1H-1,2,3-triazol-4...) Show SMILES CCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O5/c1-2-3-4-5-6-7-8-9-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341333 (CHEMBL1766470 | rel-(1R,2S,4R,5S)-6-[[1-(3,3-Diphe...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCC(c3ccccc3)c3ccccc3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C24H30N4O5/c29-20-19(21(30)23(32)24(33)22(20)31)25-13-17-14-28(27-26-17)12-11-18(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,14,18-25,29-33H,11-13H2/t19-,20-,21+,22+,23-,24-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50569050 (CHEMBL4848172) Show SMILES CCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](C)NC(=O)c1ccc(CCCCCCC)cc1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341331 (CHEMBL1766489 | rel-(1R,2S,4R,5S)-6-[[1-(10-Hydrox...) Show SMILES OCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O6/c24-10-8-6-4-2-1-3-5-7-9-23-12-13(21-22-23)11-20-14-15(25)17(27)19(29)18(28)16(14)26/h12,14-20,24-29H,1-11H2/t14-,15-,16+,17+,18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341334 (CHEMBL1766473 | rel-(1R,2S,4R,5S)-6-[(1-Adamantyl-...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CC34CC5CC(CC(C5)C3)C4)nn2)[C@@H](O)[C@@H]1O |r,TLB:12:13:16:20.19.18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13,12:13:16.15.20:18| Show InChI InChI=1S/C20H32N4O5/c25-15-14(16(26)18(28)19(29)17(15)27)21-7-13-8-24(23-22-13)9-20-4-10-1-11(5-20)3-12(2-10)6-20/h8,10-12,14-19,21,25-29H,1-7,9H2/t10?,11?,12?,14-,15-,16+,17+,18-,19-,20?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Competitive inhibition of recombinant glucocerebrosidase				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318559 ((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...) Show SMILES CCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C17H32N4O5/c1-2-3-4-5-6-7-8-21-10-11(19-20-21)9-18-12-13(22)15(24)17(26)16(25)14(12)23/h10,12-18,22-26H,2-9H2,1H3/t12-,13-,14+,15+,16-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50569051 (CHEMBL4865548) Show SMILES CCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](C)NC(=O)CCCCCCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318558 ((1R,2S,3r,4R,5S,6s)-6-((1-(6-propoxyhexyl)-1H-1,2,...) Show SMILES CCCOCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O6/c1-2-8-28-9-6-4-3-5-7-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Phospholipase C (Bacillus cereus)	BDBM50332109 (CHEMBL1287861 | Tert-butyl 1-(benzyloxy[3-(dimethy...) Show SMILES CCCCCCCCCCC(NC(=O)OC(C)(C)C)C(=O)N(CCCN(C)C)OCc1ccccc1 Show InChI InChI=1S/C29H51N3O4/c1-7-8-9-10-11-12-13-17-21-26(30-28(34)36-29(2,3)4)27(33)32(23-18-22-31(5)6)35-24-25-19-15-14-16-20-25/h14-16,19-20,26H,7-13,17-18,21-24H2,1-6H3,(H,30,34)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Advance Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL					Assay Description Non-competitive inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysis				Bioorg Med Chem 18: 8549-55 (2010) Article DOI: 10.1016/j.bmc.2010.10.031 BindingDB Entry DOI: 10.7270/Q2VH5P32
					More data for this Ligand-Target Pair
Phospholipase C (Bacillus cereus)	BDBM50332115 (3-(N-(benzyloxy)-2-(tert-butyloxycarbonylamino)dod...) Show SMILES CCCCCCCCCCC(NC(=O)OC(C)(C)C)C(=O)N(CCC[N+](C)(C)C)OCc1ccccc1 Show InChI InChI=1S/C30H53N3O4/c1-8-9-10-11-12-13-14-18-22-27(31-29(35)37-30(2,3)4)28(34)32(23-19-24-33(5,6)7)36-25-26-20-16-15-17-21-26/h15-17,20-21,27H,8-14,18-19,22-25H2,1-7H3/p+1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Advance Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL					Assay Description Mixed-type inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysis				Bioorg Med Chem 18: 8549-55 (2010) Article DOI: 10.1016/j.bmc.2010.10.031 BindingDB Entry DOI: 10.7270/Q2VH5P32
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50569048 (CHEMBL4861323) Show SMILES CCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](C)NC(=O)c1ccc(OCCCOCOC)cc1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Rattus norvegicus)	BDBM50187501 (CHEMBL3827445) Show SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CP(O)(O)=O |r| Show InChI InChI=1S/C18H40NO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of rat liver microsomal S1PL using varying levels of [3-3H]-D(+) erythro-sphinganine-1-phosphate as substrate incubated for 15...				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Rattus norvegicus)	BDBM50187501 (CHEMBL3827445) Show SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CP(O)(O)=O |r| Show InChI InChI=1S/C18H40NO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL					Assay Description Competitive inhibition of rat S1PL in presence of D(+)-erythro-sphinganine-1-phosphate measured after 15 mins by Dixon plot analysis				Bioorg Med Chem 24: 4381-4389 (2016) Article DOI: 10.1016/j.bmc.2016.07.033 BindingDB Entry DOI: 10.7270/Q2862JDX
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50569049 (CHEMBL4878103) Show SMILES CCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](C)NC(=O)c1ccc(OCCCCOCOC)cc1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558370 (CHEMBL4784427) Show SMILES CCCCCCCCCCCCC\C=C\[C@H](O)[C@@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558364 (CHEMBL4754006) Show SMILES CCCCCCCCCCCCCCC[C@H](O)[C@@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318557 ((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558371 (CHEMBL4763050) Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Phospholipase C (Bacillus cereus)	BDBM50332105 (1-(hydroxy(2-(trimethylammonio)ethyl)amino)-1-oxod...) Show SMILES CCCCCCCCCCC([NH3+])C(=O)N(O)CC[N+](C)(C)C Show InChI InChI=1S/C17H38N3O2/c1-5-6-7-8-9-10-11-12-13-16(18)17(21)19(22)14-15-20(2,3)4/h16,22H,5-15,18H2,1-4H3/q+1/p+1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Advance Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL					Assay Description Uncompetitive inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysis				Bioorg Med Chem 18: 8549-55 (2010) Article DOI: 10.1016/j.bmc.2010.10.031 BindingDB Entry DOI: 10.7270/Q2VH5P32
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558367 (CHEMBL4754871) Show SMILES CCCCCCCCCCCCCCC[C@H](O)[C@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558368 (CHEMBL4748268) Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558365 (CHEMBL4756827) Show SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318556 ((1R,2S,3r,4R,5S,6s)-6-[(1-Phenethyl-1H-1,2,3-triaz...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCc3ccccc3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C17H24N4O5/c22-13-12(14(23)16(25)17(26)15(13)24)18-8-11-9-21(20-19-11)7-6-10-4-2-1-3-5-10/h1-5,9,12-18,22-26H,6-8H2/t12-,13-,14+,15+,16-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318554 ((1R,2S,3r,4R,5S,6s)-6-(3-(1-octyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-11-23-12-13(21-22-23)9-8-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318555 ((1R,2S,3r,4R,5S,6s)-6-[2-(1-Undecyl-1H-1,2,3-triaz...) Show SMILES CCCCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-13-25-14-15(23-24-25)11-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558369 (CHEMBL4791053) Show SMILES CCCCCCCCCCCCC\C=C\[C@H](O)[C@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Alkaline ceramidase 3 (Mus musculus)	BDBM50569048 (CHEMBL4861323) Show SMILES CCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](C)NC(=O)c1ccc(OCCCOCOC)cc1 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.55E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Phospholipase C (Bacillus cereus)	BDBM50332119 (1-(hydroxy[3-(trimethylammonio)propyl]amino)-1-oxo...) Show SMILES CCCCCCCCCCC([NH3+])C(=O)N(O)CCC[N+](C)(C)C Show InChI InChI=1S/C18H40N3O2/c1-5-6-7-8-9-10-11-12-14-17(19)18(22)20(23)15-13-16-21(2,3)4/h17,23H,5-16,19H2,1-4H3/q+1/p+1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Advance Chemistry of Catalonia (IQAC-CSIC) Curated by ChEMBL					Assay Description Mixed-type inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysis				Bioorg Med Chem 18: 8549-55 (2010) Article DOI: 10.1016/j.bmc.2010.10.031 BindingDB Entry DOI: 10.7270/Q2VH5P32
					More data for this Ligand-Target Pair
Alkaline ceramidase 3 (Mus musculus)	BDBM50569049 (CHEMBL4878103) Show SMILES CCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](C)NC(=O)c1ccc(OCCCCOCOC)cc1 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM50558366 (CHEMBL4763487) Show SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@@H](COP(O)(O)=O)N=[N+]=[N-] |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.67E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2016.08.008 BindingDB Entry DOI: 10.7270/Q29W0K5N
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50569052 (CHEMBL4866400) Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)NCCCCCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human ASAH2 using RBM14C24 fluorogenic substrate measured at pH 7.5				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50586222 (CHEMBL5082786) Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccnc3C)n(Cc3ccco3)c(=O)c21 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318564 ((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318564 ((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30.2	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341332 (CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(Cc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C30H34N4O7/c35-26-25(27(36)29(38)30(39)28(26)37)31-14-22-16-34(33-32-22)15-21-11-23(40-17-19-7-3-1-4-8-19)13-24(12-21)41-18-20-9-5-2-6-10-20/h1-13,16,25-31,35-39H,14-15,17-18H2/t25-,26-,27+,28+,29-,30-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	5.2	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysis				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341324 (CHEMBL1766482 | rel-(1R,2S,4R,5S)-6-[[1-Undecyl-1H...) Show SMILES CCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C20H38N4O5/c1-2-3-4-5-6-7-8-9-10-11-24-13-14(22-23-24)12-21-15-16(25)18(27)20(29)19(28)17(15)26/h13,15-21,25-29H,2-12H2,1H3/t15-,16-,17+,18+,19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	5.2	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysis				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50341332 (CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...) Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(Cc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C30H34N4O7/c35-26-25(27(36)29(38)30(39)28(26)37)31-14-22-16-34(33-32-22)15-21-11-23(40-17-19-7-3-1-4-8-19)13-24(12-21)41-18-20-9-5-2-6-10-20/h1-13,16,25-31,35-39H,14-15,17-18H2/t25-,26-,27+,28+,29-,30-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	n/a
Spanish National Research Council (Consejo Superior de Investigaciones Cienti£?ficas) Curated by ChEMBL					Assay Description Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 7.4 after 10 mins by fluorometric analysis				J Med Chem 54: 2069-79 (2011) Article DOI: 10.1021/jm101204u BindingDB Entry DOI: 10.7270/Q24F1R18
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318564 ((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50586222 (CHEMBL5082786) Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccnc3C)n(Cc3ccco3)c(=O)c21 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50586230 (CHEMBL5081350) Show SMILES COc1ccccc1NC(=O)CSc1nc2sc3CN(CCc3c2c(=O)n1Cc1ccco1)C(C)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752
					More data for this Ligand-Target Pair

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