Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292221 ((S)-3-(2,4-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50366689 (GHRELIN) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292225 ((S)-3-(2,5-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292228 ((S)-3-(2,3-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292230 ((S)-3-(2,6-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292223 ((R)-3-(3-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292227 ((R)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(3-methox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292226 ((R)-3-(4-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292229 ((R)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(4-methox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292224 (1-(2-Diethylamino-ethyl)-3-hydroxy-2-oxo-3-phenyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292222 ((S)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(2-methox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Mus musculus) | BDBM50334216 (2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at mouse PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50334216 (2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50334219 (2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM28700 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50334218 (2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50334217 (5-chloro-2-(3-(2-(4-methoxybenzoyl)-4-methyl-1H-py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50049240 ((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 390 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50334216 (2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50334219 (2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50334218 (2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50334217 (5-chloro-2-(3-(2-(4-methoxybenzoyl)-4-methyl-1H-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | >9.00E+4 | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co, Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells cotransfected with Gal4 by luciferase reporter gene assay | Bioorg Med Chem Lett 21: 220-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.032 BindingDB Entry DOI: 10.7270/Q2668DGT | |||||||||||
More data for this Ligand-Target Pair |