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Found 112 hits with Last Name = 'pascual' and Initial = 'j'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084801
PNG
(4-(2-{[7-(Quinolin-2-ylmethoxy)-naphthalene-2-carb...)
Show SMILES OC(=O)c1ccc(CCNC(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C30H24N2O4/c33-29(31-16-15-20-5-7-23(8-6-20)30(34)35)24-10-9-21-12-14-27(18-25(21)17-24)36-19-26-13-11-22-3-1-2-4-28(22)32-26/h1-14,17-18H,15-16,19H2,(H,31,33)(H,34,35)
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 1.05n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084814
PNG
(4-(4-(7-(quinolin-2-ylmethoxy)-2-naphthamido)pheny...)
Show SMILES OC(=O)CCCc1ccc(NC(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C31H26N2O4/c34-30(35)7-3-4-21-8-14-26(15-9-21)33-31(36)24-11-10-22-13-17-28(19-25(22)18-24)37-20-27-16-12-23-5-1-2-6-29(23)32-27/h1-2,5-6,8-19H,3-4,7,20H2,(H,33,36)(H,34,35)
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 1.5n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50052024
PNG
(CHEMBL787 | montelukast)
Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r|
Show InChI InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1
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 2.10n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084800
PNG
((4-{2-[7-(Quinolin-2-ylmethoxy)-naphthalene-2-sulf...)
Show SMILES OC(=O)Cc1ccc(CCNS(=O)(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C30H26N2O5S/c33-30(34)17-22-7-5-21(6-8-22)15-16-31-38(35,36)28-14-11-23-10-13-27(18-25(23)19-28)37-20-26-12-9-24-3-1-2-4-29(24)32-26/h1-14,18-19,31H,15-17,20H2,(H,33,34)
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 2.40n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084805
PNG
(4-{2-[7-(Quinolin-2-ylmethoxy)-naphthalene-2-sulfo...)
Show SMILES OC(=O)c1ccc(CCNS(=O)(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C29H24N2O5S/c32-29(33)23-7-5-20(6-8-23)15-16-30-37(34,35)27-14-11-21-10-13-26(17-24(21)18-27)36-19-25-12-9-22-3-1-2-4-28(22)31-25/h1-14,17-18,30H,15-16,19H2,(H,32,33)
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 2.60n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084822
PNG
(4-(2-((7-(quinolin-2-ylmethoxy)naphthalen-2-yl)met...)
Show SMILES OC(=O)c1ccc(CCOCc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C30H25NO4/c32-30(33)25-9-5-21(6-10-25)15-16-34-19-22-7-8-23-12-14-28(18-26(23)17-22)35-20-27-13-11-24-3-1-2-4-29(24)31-27/h1-14,17-18H,15-16,19-20H2,(H,32,33)
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 2.70n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084775
PNG
(7-(Quinolin-2-ylmethoxy)-naphthalene-2-carboxylic ...)
Show SMILES O=C(NCCc1ccc(cc1)-c1nnn[nH]1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1
Show InChI InChI=1S/C30H24N6O2/c37-30(31-16-15-20-5-7-23(8-6-20)29-33-35-36-34-29)24-10-9-21-12-14-27(18-25(21)17-24)38-19-26-13-11-22-3-1-2-4-28(22)32-26/h1-14,17-18H,15-16,19H2,(H,31,37)(H,33,34,35,36)
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 3.40n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084797
PNG
(4-(2-methyl-1-(7-(quinolin-2-ylmethoxy)naphthalene...)
Show SMILES CC(C)(CNS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C31H28N2O5S/c1-31(2,25-12-7-23(8-13-25)30(34)35)20-32-39(36,37)28-16-11-21-10-15-27(17-24(21)18-28)38-19-26-14-9-22-5-3-4-6-29(22)33-26/h3-18,32H,19-20H2,1-2H3,(H,34,35)
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 3.80n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084816
PNG
(4-{2-Hydroxy-3-[7-(quinolin-2-ylmethoxy)-naphthale...)
Show SMILES OC(COc1ccc(cc1)C(O)=O)COc1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1
Show InChI InChI=1S/C30H25NO6/c32-25(18-36-26-11-8-22(9-12-26)30(33)34)19-37-28-14-7-20-6-13-27(15-23(20)16-28)35-17-24-10-5-21-3-1-2-4-29(21)31-24/h1-16,25,32H,17-19H2,(H,33,34)
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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084790
PNG
(4-{2-[7-(Quinolin-2-ylmethoxy)-naphthalene-2-sulfo...)
Show SMILES CC(Cc1ccc(cc1)C(O)=O)NS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1
Show InChI InChI=1S/C30H26N2O5S/c1-20(16-21-6-8-24(9-7-21)30(33)34)32-38(35,36)28-15-12-22-11-14-27(17-25(22)18-28)37-19-26-13-10-23-4-2-3-5-29(23)31-26/h2-15,17-18,20,32H,16,19H2,1H3,(H,33,34)
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 4.10n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084794
PNG
(3-(2-((7-(quinolin-2-ylmethoxy)naphthalen-2-yl)met...)
Show SMILES OC(=O)c1cccc(CCOCc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)c1
Show InChI InChI=1S/C30H25NO4/c32-30(33)25-6-3-4-21(16-25)14-15-34-19-22-8-9-23-11-13-28(18-26(23)17-22)35-20-27-12-10-24-5-1-2-7-29(24)31-27/h1-13,16-18H,14-15,19-20H2,(H,32,33)
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 4.60n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084795
PNG
(4-(4-{2-[4-(7-Chloro-quinolin-2-ylmethoxy)-phenyl]...)
Show SMILES OC(=O)CCCc1ccc(NC(=O)Cc2ccc(OCc3ccc4ccc(Cl)cc4n3)cc2)cc1
Show InChI InChI=1S/C28H25ClN2O4/c29-22-10-8-21-9-13-24(30-26(21)17-22)18-35-25-14-6-20(7-15-25)16-27(32)31-23-11-4-19(5-12-23)2-1-3-28(33)34/h4-15,17H,1-3,16,18H2,(H,31,32)(H,33,34)
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 4.80n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084817
PNG
(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-N-[4-...)
Show SMILES O=C(Cc1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1)NCc1ccc(cc1)-c1nnn[nH]1
Show InChI InChI=1S/C30H24N6O2/c37-29(31-18-20-5-8-23(9-6-20)30-33-35-36-34-30)16-21-7-10-25-17-27(14-12-24(25)15-21)38-19-26-13-11-22-3-1-2-4-28(22)32-26/h1-15,17H,16,18-19H2,(H,31,37)(H,33,34,35,36)
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 5.5n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084772
PNG
(4-{3-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yloxy]...)
Show SMILES OC(=O)c1ccc(CCCOc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C30H25NO4/c32-30(33)24-9-7-21(8-10-24)4-3-17-34-27-15-12-22-13-16-28(19-25(22)18-27)35-20-26-14-11-23-5-1-2-6-29(23)31-26/h1-2,5-16,18-19H,3-4,17,20H2,(H,32,33)
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 5.60n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084815
PNG
(4-(((7-(quinolin-2-ylmethoxy)naphthalen-2-yl)metho...)
Show SMILES OC(=O)c1ccc(COCc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C29H23NO4/c31-29(32)24-9-5-20(6-10-24)17-33-18-21-7-8-22-12-14-27(16-25(22)15-21)34-19-26-13-11-23-3-1-2-4-28(23)30-26/h1-16H,17-19H2,(H,31,32)
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 7.30n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084780
PNG
(4-(4-{2-[4-(Quinolin-2-ylmethoxy)-phenyl]-acetylam...)
Show SMILES OC(=O)CCCc1ccc(NC(=O)Cc2ccc(OCc3ccc4ccccc4n3)cc2)cc1
Show InChI InChI=1S/C28H26N2O4/c31-27(30-23-13-8-20(9-14-23)4-3-7-28(32)33)18-21-10-16-25(17-11-21)34-19-24-15-12-22-5-1-2-6-26(22)29-24/h1-2,5-6,8-17H,3-4,7,18-19H2,(H,30,31)(H,32,33)
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Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084792
PNG
(7-(Quinolin-2-ylmethoxy)-naphthalene-2-carboxylic ...)
Show SMILES O=C(NCc1ccc(cc1)-c1nnn[nH]1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1
Show InChI InChI=1S/C29H22N6O2/c36-29(30-17-19-5-7-22(8-6-19)28-32-34-35-33-28)23-10-9-20-12-14-26(16-24(20)15-23)37-18-25-13-11-21-3-1-2-4-27(21)31-25/h1-16H,17-18H2,(H,30,36)(H,32,33,34,35)
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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084774
PNG
((2-{1-[7-(Quinolin-2-ylmethoxy)-naphthalene-2-sulf...)
Show SMILES CC(NS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccccc1CC(O)=O
Show InChI InChI=1S/C30H26N2O5S/c1-20(28-8-4-2-7-23(28)18-30(33)34)32-38(35,36)27-15-12-21-11-14-26(16-24(21)17-27)37-19-25-13-10-22-6-3-5-9-29(22)31-25/h2-17,20,32H,18-19H2,1H3,(H,33,34)
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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084777
PNG
(4-((7-(quinolin-2-ylmethoxy)naphthalen-2-ylcarbamo...)
Show SMILES OC(=O)c1ccc(COC(=O)Nc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C29H22N2O5/c32-28(33)22-7-5-19(6-8-22)17-36-29(34)31-24-12-9-20-11-14-26(16-23(20)15-24)35-18-25-13-10-21-3-1-2-4-27(21)30-25/h1-16H,17-18H2,(H,31,34)(H,32,33)
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Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084781
PNG
(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-N-[4-...)
Show SMILES CC(C(=O)NCc1ccc(cc1)-c1nnn[nH]1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C31H26N6O2/c1-20(31(38)32-18-21-6-8-23(9-7-21)30-34-36-37-35-30)24-10-11-26-17-28(15-13-25(26)16-24)39-19-27-14-12-22-4-2-3-5-29(22)33-27/h2-17,20H,18-19H2,1H3,(H,32,38)(H,34,35,36,37)
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 9.20n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084784
PNG
(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-N-[2-...)
Show SMILES CC(C(=O)NCc1ccccc1-c1nnn[nH]1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C31H26N6O2/c1-20(31(38)32-18-25-7-2-4-8-28(25)30-34-36-37-35-30)22-10-11-24-17-27(15-13-23(24)16-22)39-19-26-14-12-21-6-3-5-9-29(21)33-26/h2-17,20H,18-19H2,1H3,(H,32,38)(H,34,35,36,37)
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 12n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084773
PNG
(7-(Quinolin-2-ylmethoxy)-naphthalene-2-carboxylic ...)
Show SMILES O=C(NCCCc1ccc(cc1)-c1nnn[nH]1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1
Show InChI InChI=1S/C31H26N6O2/c38-31(32-17-3-4-21-7-9-24(10-8-21)30-34-36-37-35-30)25-12-11-22-14-16-28(19-26(22)18-25)39-20-27-15-13-23-5-1-2-6-29(23)33-27/h1-2,5-16,18-19H,3-4,17,20H2,(H,32,38)(H,34,35,36,37)
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 13n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084811
PNG
(4-(2-(N-methyl-7-(quinolin-2-ylmethoxy)naphthalene...)
Show SMILES CN(CCc1ccc(cc1)C(O)=O)S(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1
Show InChI InChI=1S/C30H26N2O5S/c1-32(17-16-21-6-8-24(9-7-21)30(33)34)38(35,36)28-15-12-22-11-14-27(18-25(22)19-28)37-20-26-13-10-23-4-2-3-5-29(23)31-26/h2-15,18-19H,16-17,20H2,1H3,(H,33,34)
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 13n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084791
PNG
(7-(Quinolin-2-ylmethoxy)-naphthalene-2-carboxylic ...)
Show SMILES Cc1ccccc1S(=O)(=O)NC(=O)c1ccc(CCNC(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C37H31N3O5S/c1-25-6-2-5-9-35(25)46(43,44)40-37(42)29-12-10-26(11-13-29)20-21-38-36(41)30-15-14-27-17-19-33(23-31(27)22-30)45-24-32-18-16-28-7-3-4-8-34(28)39-32/h2-19,22-23H,20-21,24H2,1H3,(H,38,41)(H,40,42)
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 15n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084778
PNG
(4-{5-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-[1...)
Show SMILES OC(=O)c1ccc(Cc2noc(n2)-c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C30H21N3O4/c34-30(35)22-7-5-19(6-8-22)15-28-32-29(37-33-28)23-10-9-20-12-14-26(17-24(20)16-23)36-18-25-13-11-21-3-1-2-4-27(21)31-25/h1-14,16-17H,15,18H2,(H,34,35)
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 15n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084783
PNG
(4-(4-(7-(quinolin-2-ylmethoxy)naphthalen-2-yloxy)b...)
Show SMILES OC(=O)c1ccc(CCCCOc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Show InChI InChI=1S/C31H27NO4/c33-31(34)25-10-8-22(9-11-25)5-3-4-18-35-28-16-13-23-14-17-29(20-26(23)19-28)36-21-27-15-12-24-6-1-2-7-30(24)32-27/h1-2,6-17,19-20H,3-5,18,21H2,(H,33,34)
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 21n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084812
PNG
(6-(Quinolin-2-ylmethoxy)-naphthalene-2-carboxylic ...)
Show SMILES O=C(NCc1cccc(c1)-c1nnn[nH]1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C29H22N6O2/c36-29(30-17-19-4-3-6-23(14-19)28-32-34-35-33-28)24-9-8-22-16-26(13-11-21(22)15-24)37-18-25-12-10-20-5-1-2-7-27(20)31-25/h1-16H,17-18H2,(H,30,36)(H,32,33,34,35)
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 28n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084779
PNG
(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-N-[3-...)
Show SMILES CC(C(=O)NCc1cccc(c1)-c1nnn[nH]1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C31H26N6O2/c1-20(31(38)32-18-21-5-4-7-26(15-21)30-34-36-37-35-30)23-9-10-25-17-28(14-12-24(25)16-23)39-19-27-13-11-22-6-2-3-8-29(22)33-27/h2-17,20H,18-19H2,1H3,(H,32,38)(H,34,35,36,37)
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 29n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084820
PNG
(4-(4-(6-(quinolin-2-ylmethoxy)-2-naphthamido)pheny...)
Show SMILES OC(=O)CCCc1ccc(NC(=O)c2ccc3cc(OCc4ccc5ccccc5n4)ccc3c2)cc1
Show InChI InChI=1S/C31H26N2O4/c34-30(35)7-3-4-21-8-14-26(15-9-21)33-31(36)25-11-10-24-19-28(17-13-23(24)18-25)37-20-27-16-12-22-5-1-2-6-29(22)32-27/h1-2,5-6,8-19H,3-4,7,20H2,(H,33,36)(H,34,35)
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 30n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084807
PNG
(1-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-ylmethyl]...)
Show SMILES OC(=O)c1ccc2n(Cc3ccc4ccc(OCc5ccc6ccccc6n5)cc4c3)ccc2c1
Show InChI InChI=1S/C30H22N2O3/c33-30(34)24-9-12-29-23(16-24)13-14-32(29)18-20-5-6-21-8-11-27(17-25(21)15-20)35-19-26-10-7-22-3-1-2-4-28(22)31-26/h1-17H,18-19H2,(H,33,34)
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 30n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084809
PNG
(4-Oxo-8-{[7-(quinolin-2-ylmethoxy)-naphthalene-2-c...)
Show SMILES OC(=O)c1cc(=O)c2cccc(NC(=O)c3ccc4ccc(OCc5ccc6ccccc6n5)cc4c3)c2o1
Show InChI InChI=1S/C31H20N2O6/c34-27-16-28(31(36)37)39-29-24(27)5-3-7-26(29)33-30(35)20-9-8-18-11-13-23(15-21(18)14-20)38-17-22-12-10-19-4-1-2-6-25(19)32-22/h1-16H,17H2,(H,33,35)(H,36,37)
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 30n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084821
PNG
(CHEMBL337162 | N-[4-(2,3-Dihydro-1H-tetrazol-5-ylm...)
Show SMILES CC(C(=O)Nc1ccc(CC2=NNNN2)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 |t:10|
Show InChI InChI=1S/C31H28N6O2/c1-20(31(38)33-26-12-6-21(7-13-26)16-30-34-36-37-35-30)23-8-9-25-18-28(15-11-24(25)17-23)39-19-27-14-10-22-4-2-3-5-29(22)32-27/h2-15,17-18,20,36-37H,16,19H2,1H3,(H,33,38)(H,34,35)
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 34n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084785
PNG
((4-{2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Show SMILES CC(C(=O)Nc1ccc(CC(O)=O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C31H26N2O4/c1-20(31(36)33-26-12-6-21(7-13-26)16-30(34)35)23-8-9-25-18-28(15-11-24(25)17-23)37-19-27-14-10-22-4-2-3-5-29(22)32-27/h2-15,17-18,20H,16,19H2,1H3,(H,33,36)(H,34,35)
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 36n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084771
PNG
(4-(4-{2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]...)
Show SMILES CC(C(=O)Nc1ccc(CCCC(O)=O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C33H30N2O4/c1-22(33(38)35-28-15-9-23(10-16-28)5-4-8-32(36)37)25-11-12-27-20-30(18-14-26(27)19-25)39-21-29-17-13-24-6-2-3-7-31(24)34-29/h2-3,6-7,9-20,22H,4-5,8,21H2,1H3,(H,35,38)(H,36,37)
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 38n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084787
PNG
(4-(4-{2-[3-(Quinolin-2-ylmethoxy)-phenyl]-acetylam...)
Show SMILES OC(=O)CCCc1ccc(NC(=O)Cc2cccc(OCc3ccc4ccccc4n3)c2)cc1
Show InChI InChI=1S/C28H26N2O4/c31-27(30-23-14-11-20(12-15-23)5-4-10-28(32)33)18-21-6-3-8-25(17-21)34-19-24-16-13-22-7-1-2-9-26(22)29-24/h1-3,6-9,11-17H,4-5,10,18-19H2,(H,30,31)(H,32,33)
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 40n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084799
PNG
(4-(4-(4-(quinolin-2-ylmethoxy)benzylcarbamoyl)phen...)
Show SMILES OC(=O)CCCc1ccc(cc1)C(=O)NCc1ccc(OCc2ccc3ccccc3n2)cc1
Show InChI InChI=1S/C28H26N2O4/c31-27(32)7-3-4-20-8-12-23(13-9-20)28(33)29-18-21-10-16-25(17-11-21)34-19-24-15-14-22-5-1-2-6-26(22)30-24/h1-2,5-6,8-17H,3-4,7,18-19H2,(H,29,33)(H,31,32)
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 44n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084808
PNG
(3-({2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Show SMILES CC(C(=O)NCc1cccc(c1)C(O)=O)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C31H26N2O4/c1-20(30(34)32-18-21-5-4-7-26(15-21)31(35)36)23-9-10-25-17-28(14-12-24(25)16-23)37-19-27-13-11-22-6-2-3-8-29(22)33-27/h2-17,20H,18-19H2,1H3,(H,32,34)(H,35,36)
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 68n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084806
PNG
(4-({2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Show SMILES CC(C(=O)NCc1ccc(cc1)C(O)=O)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C31H26N2O4/c1-20(30(34)32-18-21-6-8-23(9-7-21)31(35)36)24-10-11-26-17-28(15-13-25(26)16-24)37-19-27-14-12-22-4-2-3-5-29(22)33-27/h2-17,20H,18-19H2,1H3,(H,32,34)(H,35,36)
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 70n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084802
PNG
(4-(2-{[7-(5-Phenyl-pyridin-2-ylmethoxy)-naphthalen...)
Show SMILES OC(=O)c1ccc(CCNC(=O)c2ccc3ccc(OCc4ccc(cn4)-c4ccccc4)cc3c2)cc1
Show InChI InChI=1S/C32H26N2O4/c35-31(33-17-16-22-6-8-25(9-7-22)32(36)37)26-11-10-24-13-15-30(19-28(24)18-26)38-21-29-14-12-27(20-34-29)23-4-2-1-3-5-23/h1-15,18-20H,16-17,21H2,(H,33,35)(H,36,37)
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 79n/an/an/an/an/an/an/an/a



Laboratorios Menarini

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Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084793
PNG
(4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromene-8-carboxyli...)
Show SMILES O=C(NCc1ccc(OCc2ccc3ccccc3n2)cc1)c1cccc2c1oc(cc2=O)-c1nnn[nH]1
Show InChI InChI=1S/C28H20N6O4/c35-24-14-25(27-31-33-34-32-27)38-26-21(24)5-3-6-22(26)28(36)29-15-17-8-12-20(13-9-17)37-16-19-11-10-18-4-1-2-7-23(18)30-19/h1-14H,15-16H2,(H,29,36)(H,31,32,33,34)
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 86n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084798
PNG
(2-[4-(Quinolin-2-ylmethoxy)-phenyl]-N-{4-[3-(1H-te...)
Show SMILES O=C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)Nc1ccc(CCCc2nnn[nH]2)cc1
Show InChI InChI=1S/C28H26N6O2/c35-28(30-23-13-8-20(9-14-23)4-3-7-27-31-33-34-32-27)18-21-10-16-25(17-11-21)36-19-24-15-12-22-5-1-2-6-26(22)29-24/h1-2,5-6,8-17H,3-4,7,18-19H2,(H,30,35)(H,31,32,33,34)
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 88n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084810
PNG
(2-[4-(Quinolin-2-ylmethoxy)-phenyl]-N-[4-(1H-tetra...)
Show SMILES O=C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)Nc1ccc(Cc2nnn[nH]2)cc1
Show InChI InChI=1S/C26H22N6O2/c33-26(28-21-10-5-18(6-11-21)15-25-29-31-32-30-25)16-19-7-13-23(14-8-19)34-17-22-12-9-20-3-1-2-4-24(20)27-22/h1-14H,15-17H2,(H,28,33)(H,29,30,31,32)
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 108n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084804
PNG
(4-{2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-pr...)
Show SMILES CC(C(=O)Nc1ccc(cc1)C(O)=O)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C30H24N2O4/c1-19(29(33)32-25-12-9-21(10-13-25)30(34)35)22-6-7-24-17-27(15-11-23(24)16-22)36-18-26-14-8-20-4-2-3-5-28(20)31-26/h2-17,19H,18H2,1H3,(H,32,33)(H,34,35)
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 118n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084813
PNG
(CHEMBL131934 | [4-({2-[6-(Quinolin-2-ylmethoxy)-na...)
Show SMILES CC(C(=O)NCc1ccc(CC(O)=O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C32H28N2O4/c1-21(32(37)33-19-23-8-6-22(7-9-23)16-31(35)36)25-10-11-27-18-29(15-13-26(27)17-25)38-20-28-14-12-24-4-2-3-5-30(24)34-28/h2-15,17-18,21H,16,19-20H2,1H3,(H,33,37)(H,35,36)
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 134n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084796
PNG
(4-Oxo-8-[4-(quinolin-2-ylmethoxy)-benzoylamino]-4H...)
Show SMILES OC(=O)c1cc(=O)c2cccc(NC(=O)c3ccc(OCc4ccc5ccccc5n4)cc3)c2o1
Show InChI InChI=1S/C27H18N2O6/c30-23-14-24(27(32)33)35-25-20(23)5-3-7-22(25)29-26(31)17-9-12-19(13-10-17)34-15-18-11-8-16-4-1-2-6-21(16)28-18/h1-14H,15H2,(H,29,31)(H,32,33)
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 168n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084786
PNG
(4-(4-{2-[6-(7-Chloro-quinolin-2-ylmethoxy)-naphtha...)
Show SMILES CC(C(=O)Nc1ccc(CCCC(O)=O)cc1)c1ccc2cc(OCc3ccc4ccc(Cl)cc4n3)ccc2c1
Show InChI InChI=1S/C33H29ClN2O4/c1-21(33(39)36-28-13-5-22(6-14-28)3-2-4-32(37)38)24-7-8-26-18-30(16-11-25(26)17-24)40-20-29-15-10-23-9-12-27(34)19-31(23)35-29/h5-19,21H,2-4,20H2,1H3,(H,36,39)(H,37,38)
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 190n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084819
PNG
(4-(2-{[7-(Quinolin-2-ylmethoxy)-chroman-2-carbonyl...)
Show SMILES OC(=O)c1ccc(CCNC(=O)C2CCc3ccc(OCc4ccc5ccccc5n4)cc3O2)cc1
Show InChI InChI=1S/C29H26N2O5/c32-28(30-16-15-19-5-7-22(8-6-19)29(33)34)26-14-11-21-10-13-24(17-27(21)36-26)35-18-23-12-9-20-3-1-2-4-25(20)31-23/h1-10,12-13,17,26H,11,14-16,18H2,(H,30,32)(H,33,34)
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 237n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084803
PNG
(2-[4-(Quinolin-2-ylmethoxy)-phenyl]-N-[4-(1H-tetra...)
Show SMILES O=C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)NCc1ccc(cc1)-c1nnn[nH]1
Show InChI InChI=1S/C26H22N6O2/c33-25(27-16-19-5-9-21(10-6-19)26-29-31-32-30-26)15-18-7-13-23(14-8-18)34-17-22-12-11-20-3-1-2-4-24(20)28-22/h1-14H,15-17H2,(H,27,33)(H,29,30,31,32)
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 250n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084818
PNG
(4-[4-(Methyl-{2-[4-(quinolin-2-ylmethoxy)-phenyl]-...)
Show SMILES CN(C(=O)Cc1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(CCCC(O)=O)cc1
Show InChI InChI=1S/C29H28N2O4/c1-31(25-15-9-21(10-16-25)5-4-8-29(33)34)28(32)19-22-11-17-26(18-12-22)35-20-24-14-13-23-6-2-3-7-27(23)30-24/h2-3,6-7,9-18H,4-5,8,19-20H2,1H3,(H,33,34)
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 297n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084776
PNG
(5-{2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-pr...)
Show SMILES CC(C(=O)NCCCCC(O)=O)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1
Show InChI InChI=1S/C28H28N2O4/c1-19(28(33)29-15-5-4-8-27(31)32)21-9-10-23-17-25(14-12-22(23)16-21)34-18-24-13-11-20-6-2-3-7-26(20)30-24/h2-3,6-7,9-14,16-17,19H,4-5,8,15,18H2,1H3,(H,29,33)(H,31,32)
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 360n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair
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