Found 81 hits with Last Name = 'trembleau' and Initial = 'l' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acetylcholinesterase
(Electrophorus electricus (Electric eel)) | BDBM50446576
(CHEMBL3109481)Show InChI InChI=1S/C17H26Br2N2O2/c1-21(2,3)9-7-5-6-8-20-16(22)12-13-10-14(18)17(23-4)15(19)11-13/h10-11H,5-9,12H2,1-4H3/p+1 | UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Troms£
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 5 mins by Dixon plot analysis |
J Nat Prod 77: 364-9 (2014)
Article DOI: 10.1021/np401002s
BindingDB Entry DOI: 10.7270/Q2R49S8B |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Electrophorus electricus (Electric eel)) | BDBM50446577
(CHEMBL3109482)Show InChI InChI=1S/C13H18Br2NO3/c1-16(2,3)5-6-19-13(17)9-7-10(14)12(18-4)11(15)8-9/h7-8H,5-6H2,1-4H3/q+1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Troms£
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 5 mins by Dixon plot analysis |
J Nat Prod 77: 364-9 (2014)
Article DOI: 10.1021/np401002s
BindingDB Entry DOI: 10.7270/Q2R49S8B |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534898
(CHEMBL4522563)Show SMILES Fc1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C21H17FN2O2S/c22-19-11-9-17(10-12-19)16-7-5-15(6-8-16)14-23-27(25,26)21-13-18-3-1-2-4-20(18)24-21/h1-13,23-24H,14H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50389939
(CHEMBL1553629)Show SMILES CCc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O/c1-2-20-21-16-18(25)8-11-22(21)27-23(20)24(29)26-13-12-17-6-9-19(10-7-17)28-14-4-3-5-15-28/h6-11,16,27H,2-5,12-15H2,1H3,(H,26,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534869
(CHEMBL4474264)Show SMILES O=S(=O)(NCc1ccc(cc1)-c1ccccc1)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H18N2O2S/c24-26(25,21-14-19-8-4-5-9-20(19)23-21)22-15-16-10-12-18(13-11-16)17-6-2-1-3-7-17/h1-14,22-23H,15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534903
(CHEMBL4580709)Show SMILES COc1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C22H20N2O3S/c1-27-20-12-10-18(11-13-20)17-8-6-16(7-9-17)15-23-28(25,26)22-14-19-4-2-3-5-21(19)24-22/h2-14,23-24H,15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534887
(CHEMBL4457926)Show SMILES COc1ccc2[nH]c(cc2c1)S(=O)(=O)NCc1ccc(cc1)-c1ccc(F)nc1 Show InChI InChI=1S/C21H18FN3O3S/c1-28-18-7-8-19-17(10-18)11-21(25-19)29(26,27)24-12-14-2-4-15(5-3-14)16-6-9-20(22)23-13-16/h2-11,13,24-25H,12H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534890
(CHEMBL4438146)Show SMILES Fc1ccc(c(F)c1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)nc1 Show InChI InChI=1S/C20H14ClF2N3O2S/c21-14-2-6-19-13(7-14)8-20(26-19)29(27,28)25-11-16-4-1-12(10-24-16)17-5-3-15(22)9-18(17)23/h1-10,25-26H,11H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534858
(CHEMBL4554003)Show SMILES Cc1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C22H20N2O2S/c1-16-6-10-18(11-7-16)19-12-8-17(9-13-19)15-23-27(25,26)22-14-20-4-2-3-5-21(20)24-22/h2-14,23-24H,15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534892
(CHEMBL4436256)Show SMILES CN(C)c1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C23H23N3O2S/c1-26(2)21-13-11-19(12-14-21)18-9-7-17(8-10-18)16-24-29(27,28)23-15-20-5-3-4-6-22(20)25-23/h3-15,24-25H,16H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534899
(CHEMBL4550424)Show SMILES Fc1ccc(c(F)c1)-c1ccc(CNS(=O)(=O)c2cc3cc(Br)ccc3[nH]2)nc1 Show InChI InChI=1S/C20H14BrF2N3O2S/c21-14-2-6-19-13(7-14)8-20(26-19)29(27,28)25-11-16-4-1-12(10-24-16)17-5-3-15(22)9-18(17)23/h1-10,25-26H,11H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534902
(CHEMBL4571226)Show SMILES Clc1ccc2cc([nH]c2c1)S(=O)(=O)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H17ClN2O2S/c22-19-11-10-18-12-21(24-20(18)13-19)27(25,26)23-14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,23-24H,14H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534862
(CHEMBL4462538)Show SMILES Fc1ccc(c(F)c1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C21H15ClF2N2O2S/c22-16-5-8-20-15(9-16)10-21(26-20)29(27,28)25-12-13-1-3-14(4-2-13)18-7-6-17(23)11-19(18)24/h1-11,25-26H,12H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534860
(CHEMBL4449492)Show SMILES Fc1ccc(c(F)n1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C20H14ClF2N3O2S/c21-15-5-7-17-14(9-15)10-19(25-17)29(27,28)24-11-12-1-3-13(4-2-12)16-6-8-18(22)26-20(16)23/h1-10,24-25H,11H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534867
(CHEMBL4447746)Show SMILES Fc1ccc2cc([nH]c2c1)S(=O)(=O)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H17FN2O2S/c22-19-11-10-18-12-21(24-20(18)13-19)27(25,26)23-14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,23-24H,14H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534895
(CHEMBL4569725)Show SMILES Fc1ccc(cn1)-c1ccc(CNS(=O)(=O)c2cc3ccc(Cl)cc3[nH]2)cc1 Show InChI InChI=1S/C20H15ClFN3O2S/c21-17-7-5-15-9-20(25-18(15)10-17)28(26,27)24-11-13-1-3-14(4-2-13)16-6-8-19(22)23-12-16/h1-10,12,24-25H,11H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534868
(CHEMBL4476181)Show SMILES Brc1ccc2[nH]c(cc2c1)S(=O)(=O)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H17BrN2O2S/c22-19-10-11-20-18(12-19)13-21(24-20)27(25,26)23-14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,23-24H,14H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534910
(CHEMBL4521762)Show SMILES O=S(=O)(NCc1ccc(cc1)-c1cccnc1)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C20H17N3O2S/c24-26(25,20-12-17-4-1-2-6-19(17)23-20)22-13-15-7-9-16(10-8-15)18-5-3-11-21-14-18/h1-12,14,22-23H,13H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534870
(CHEMBL4589557)Show SMILES Cc1c([nH]c2ccccc12)S(=O)(=O)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H20N2O2S/c1-16-20-9-5-6-10-21(20)24-22(16)27(25,26)23-15-17-11-13-19(14-12-17)18-7-3-2-4-8-18/h2-14,23-24H,15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534857
(CHEMBL4516158)Show SMILES COc1ccc2[nH]c(cc2c1)S(=O)(=O)NCc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H19N3O3S/c1-29-21-10-11-22-20(12-21)13-23(26-22)30(27,28)25-15-17-4-8-19(9-5-17)18-6-2-16(14-24)3-7-18/h2-13,25-26H,15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534911
(CHEMBL4454441)Show SMILES Fc1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3cc(Br)ccc3[nH]2)nc1 Show InChI InChI=1S/C20H15BrFN3O2S/c21-16-4-8-19-15(9-16)10-20(25-19)28(26,27)24-12-18-7-3-14(11-23-18)13-1-5-17(22)6-2-13/h1-11,24-25H,12H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534859
(CHEMBL4513527)Show SMILES COCc1c([nH]c2ccccc12)S(=O)(=O)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H22N2O3S/c1-28-16-21-20-9-5-6-10-22(20)25-23(21)29(26,27)24-15-17-11-13-19(14-12-17)18-7-3-2-4-8-18/h2-14,24-25H,15-16H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534888
(CHEMBL4453133)Show SMILES CCOc1ccc(cn1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C22H21N3O3S/c1-2-28-21-12-11-19(15-23-21)17-9-7-16(8-10-17)14-24-29(26,27)22-13-18-5-3-4-6-20(18)25-22/h3-13,15,24-25H,2,14H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534886
(CHEMBL4573137)Show SMILES O=S(=O)(NCc1ccc(cc1)-c1ccsc1)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C19H16N2O2S2/c22-25(23,19-11-16-3-1-2-4-18(16)21-19)20-12-14-5-7-15(8-6-14)17-9-10-24-13-17/h1-11,13,20-21H,12H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534897
(CHEMBL4524663)Show SMILES Fc1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3cc(Br)ccc3[nH]2)cc1 Show InChI InChI=1S/C21H16BrFN2O2S/c22-18-7-10-20-17(11-18)12-21(25-20)28(26,27)24-13-14-1-3-15(4-2-14)16-5-8-19(23)9-6-16/h1-12,24-25H,13H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534914
(CHEMBL4458317)Show SMILES OCc1c([nH]c2ccccc12)S(=O)(=O)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H20N2O3S/c25-15-20-19-8-4-5-9-21(19)24-22(20)28(26,27)23-14-16-10-12-18(13-11-16)17-6-2-1-3-7-17/h1-13,23-25H,14-15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614290
(CHEMBL5267773)Show SMILES CC1CCCN1c1ccc(CCNC(=O)c2[nH]c3ccc(Cl)cc3c2C)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534864
(CHEMBL4442859)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C22H20N2O4S2/c1-29(25,26)20-12-10-18(11-13-20)17-8-6-16(7-9-17)15-23-30(27,28)22-14-19-4-2-3-5-21(19)24-22/h2-14,23-24H,15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534861
(CHEMBL4526334)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C22H19ClN2O4S2/c1-30(26,27)20-9-6-17(7-10-20)16-4-2-15(3-5-16)14-24-31(28,29)22-13-18-12-19(23)8-11-21(18)25-22/h2-13,24-25H,14H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614288
(CHEMBL5280635)Show SMILES CCc1c([nH]c2ccc(C)cc12)C(=O)NCCc1ccc(cc1)N1CCOCC1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50139171
(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)Show SMILES CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(nc12)N1CCCC[C@H]1CCO |r| Show InChI InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534883
(CHEMBL4453296)Show SMILES Fc1ccc(cc1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)c(F)c1 Show InChI InChI=1S/C21H15ClF2N2O2S/c22-17-5-8-20-16(9-17)11-21(26-20)29(27,28)25-12-15-2-1-14(10-19(15)24)13-3-6-18(23)7-4-13/h1-11,25-26H,12H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534901
(CHEMBL4591920)Show SMILES COc1ccc(c(OC)c1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-28-19-11-12-20(22(14-19)29-2)17-9-7-16(8-10-17)15-24-30(26,27)23-13-18-5-3-4-6-21(18)25-23/h3-14,24-25H,15H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614289
(CHEMBL5281464)Show SMILES Cc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCOCC1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614287
(CHEMBL5289560)Show SMILES CCc1c([nH]c2ccc(cc12)C(F)(F)F)C(=O)NCCc1ccc(cc1)N1CCOCC1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534913
(CHEMBL4576172)Show SMILES COc1cc(ccc1O)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C22H20N2O4S/c1-28-21-12-17(10-11-20(21)25)16-8-6-15(7-9-16)14-23-29(26,27)22-13-18-4-2-3-5-19(18)24-22/h2-13,23-25H,14H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614286
(CHEMBL5287016)Show SMILES CCc1c([nH]c2ccc(C)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614291
(CHEMBL5280144) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534884
(CHEMBL4457643)Show SMILES COc1ccc2[nH]c(cc2c1)S(=O)(=O)NCc1ccc(cc1F)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H18F4N2O4S/c1-32-19-8-9-21-17(10-19)12-22(29-21)34(30,31)28-13-16-3-2-15(11-20(16)24)14-4-6-18(7-5-14)33-23(25,26)27/h2-12,28-29H,13H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534896
(CHEMBL4518284)Show SMILES CC(NS(=O)(=O)c1cc2ccccc2[nH]1)c1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H19FN2O2S/c1-15(16-6-8-17(9-7-16)18-10-12-20(23)13-11-18)25-28(26,27)22-14-19-4-2-3-5-21(19)24-22/h2-15,24-25H,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50614285
(CHEMBL5287042) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM5446
(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534889
(CHEMBL4535251)Show SMILES Nc1ccc(cn1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C20H17ClN4O2S/c21-17-6-7-18-16(9-17)10-20(25-18)28(26,27)24-11-13-1-3-14(4-2-13)15-5-8-19(22)23-12-15/h1-10,12,24-25H,11H2,(H2,22,23) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50614288
(CHEMBL5280635)Show SMILES CCc1c([nH]c2ccc(C)cc12)C(=O)NCCc1ccc(cc1)N1CCOCC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50614289
(CHEMBL5281464)Show SMILES Cc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCOCC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50614290
(CHEMBL5267773)Show SMILES CC1CCCN1c1ccc(CCNC(=O)c2[nH]c3ccc(Cl)cc3c2C)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50614287
(CHEMBL5289560)Show SMILES CCc1c([nH]c2ccc(cc12)C(F)(F)F)C(=O)NCCc1ccc(cc1)N1CCOCC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50614291
(CHEMBL5280144) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50534863
(CHEMBL4469642)Show SMILES COc1ccc2[nH]c(cc2c1)S(=O)(=O)NCc1ccc(cc1)-c1ccc(CO)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-29-21-10-11-22-20(12-21)13-23(25-22)30(27,28)24-14-16-2-6-18(7-3-16)19-8-4-17(15-26)5-9-19/h2-13,24-26H,14-15H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aberdeen
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr... |
Bioorg Med Chem Lett 26: 4403-4407 (2016)
Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50614286
(CHEMBL5287016)Show SMILES CCc1c([nH]c2ccc(C)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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