Compile Data Set for Download or QSAR

Found 50 hits with Last Name = 'meng' and Initial = 'lq'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27566 (4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...) Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant PARP2 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by ELISA				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586866 (CHEMBL5086559) Show SMILES COc1cc(ccc1N(C)c1ncc2N(C)C(=O)[C@@H](C)N(C3CCCC3)c2n1)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586860 (CHEMBL5092812) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD3 BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD2 BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD3 BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586864 (CHEMBL5085356) Show SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)[C@@H](C)N(C3CCCC3)c2n1)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD3 BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586855 (CHEMBL5076077) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586871 (CHEMBL5094534) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3cccc(c3)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD3 BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD2 BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586867 (CHEMBL5085883) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(Cc4nc5c(cccc5[nH]4)C(N)=O)cc3OC)ncc2N(C)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586866 (CHEMBL5086559) Show SMILES COc1cc(ccc1N(C)c1ncc2N(C)C(=O)[C@@H](C)N(C3CCCC3)c2n1)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586870 (CHEMBL5094051) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(C)c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586855 (CHEMBL5076077) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586864 (CHEMBL5085356) Show SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)[C@@H](C)N(C3CCCC3)c2n1)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586869 (CHEMBL5071405) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(CC(=O)NCc4nc5c(cccc5[nH]4)C(N)=O)cc3OC)ncc2N(C)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	276	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586861 (CHEMBL5089076) Show SMILES CCOc1cc(ccc1Nc1ncc2N(C)C(=O)[C@@H](CC)N(C3CCCC3)c2n1)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	306	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRDT BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586856 (CHEMBL5083420) Show SMILES CC[C@H]1N(Cc2ccc(C)s2)c2nc(Nc3ccc(cc3OC)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586868 (CHEMBL5094572) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NCc3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	341	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586867 (CHEMBL5085883) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(Cc4nc5c(cccc5[nH]4)C(N)=O)cc3OC)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	355	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586868 (CHEMBL5094572) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NCc3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	381	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD2 BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD2 BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586857 (CHEMBL5077940) Show SMILES CC[C@H]1N(Cc2ccccc2)c2nc(Nc3ccc(cc3OC)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	461	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586869 (CHEMBL5071405) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(CC(=O)NCc4nc5c(cccc5[nH]4)C(N)=O)cc3OC)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	498	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586859 (CHEMBL5094021) Show SMILES CC[C@H]1N(Cc2ccc(OC)cc2OC)c2nc(Nc3ccc(cc3OC)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	588	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRDT BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586871 (CHEMBL5094534) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3cccc(c3)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	693	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586860 (CHEMBL5092812) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	842	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD4 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRDT BD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRDT BD2 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586858 (CHEMBL5077464) Show SMILES CC[C@H]1N(Cc2cccc(c2)C(F)(F)F)c2nc(Nc3ccc(cc3OC)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586863 (CHEMBL5092201) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC3CCCC3)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant PLK1 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo luminescence kinase assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50586862 (CHEMBL5083406) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC(C)C)-c3nc4c(cccc4[nH]3)C(N)=O)ncc2N(C)C1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP1 (unknown origin) incubated for 45 mins in presence of biotinylated-NAD+ by microplate reader analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of P300 (unknown orign) using acetyl-CoA as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by micro...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 1 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 1 (Homo sapiens (Human))	BDBM50365262 ((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...) Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant BRD1 (unknown origin) incubated for 120 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50586865 (CHEMBL5084388) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)N(C)c1ccc(cc1OC)-c1nc2c(cccc2[nH]1)C(N)=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of P300 (unknown orign) using acetyl-CoA as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by micro...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01535 BindingDB Entry DOI: 10.7270/Q22N566V
					More data for this Ligand-Target Pair