BindingDB PrimarySearch

Found 103 hits with Last Name = 'ishigami-yuasa' and Initial = 'm'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560445 (CHEMBL4792789) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560439 (CHEMBL4762099) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM35909 (2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50123007 (CHEMBL3622589) Show SMILES Clc1cccc(Cl)c1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122954 (CHEMBL3622579) Show SMILES Nc1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560448 (CHEMBL4759888) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560415 (CHEMBL4797256) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450199 (CHEMBL4173412) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450187 (CHEMBL4166357) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450200 (CHEMBL4161797) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450205 (CHEMBL4174659) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450206 (CHEMBL4174266) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122953 (CHEMBL3622578) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560424 (CHEMBL4751500) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450203 (CHEMBL4162851) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50442124 (CHEMBL2441094) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50123010 (CHEMBL3622590) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560420 (CHEMBL4759820) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122957 (CHEMBL3622581) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560419 (CHEMBL4753158) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50183678 (4-(2-chlorobenzyl)phthalazin-1(2H)-one \| CHEMBL378...) Show SMILES Clc1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122962 (CHEMBL3622587) Show SMILES Cc1cccc(C)c1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560417 (CHEMBL4750439) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560428 (CHEMBL4783530) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560430 (CHEMBL4758154) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122958 (CHEMBL3622583) Show SMILES CCN(CC)c1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450186 (CHEMBL4167449) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560429 (CHEMBL4747390) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122960 (CHEMBL3622585) Show SMILES CN(C)c1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560421 (CHEMBL4793138) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560437 (CHEMBL4748104) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560433 (CHEMBL4744527) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560438 (CHEMBL4795291) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560432 (CHEMBL4757952) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267911 (CHEMBL4096245) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267897 (CHEMBL4092297) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560418 (CHEMBL4748683) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560426 (CHEMBL4757062) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450202 (CHEMBL4171945) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560444 (CHEMBL4796271) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450189 (CHEMBL4167057) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450204 (CHEMBL4159542) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560422 (CHEMBL4762871) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122952 (CHEMBL3622576) Show SMILES FC(F)(F)c1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50122959 (CHEMBL3622584) Show SMILES CCNc1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50123006 (CHEMBL3622588) Show SMILES Fc1cccc(F)c1Cc1n[nH]c(=O)c2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.002 BindingDB Entry DOI: 10.7270/Q2348N6H
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Rattus norvegicus)	BDBM50267896 (CHEMBL4064614) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan. Curated by ChEMBL					Assay Description Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...				Bioorg Med Chem 25: 3845-3852 (2017) Article DOI: 10.1016/j.bmc.2017.05.034 BindingDB Entry DOI: 10.7270/Q22Z1811
					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50450201 (CHEMBL4165227) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay				Bioorg Med Chem 26: 5118-5127 (2018) Article DOI: 10.1016/j.bmc.2018.09.008 BindingDB Entry DOI: 10.7270/Q2P271PJ
Ochanomizu University Curated by ChEMBL					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50560440 (CHEMBL4783506) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair
STE20/SPS1-related proline-alanine-rich protein kinase (Homo sapiens (Human))	BDBM50350105 (CHEMBL1814047) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SPAK (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127408 BindingDB Entry DOI: 10.7270/Q25D8WJ8
TBA					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 103 total ) | Next | Last >>