BindingDB PrimarySearch

Found 59 hits with Last Name = 'nguyen' and Initial = 'mt'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50269559 (2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) Show SMILES Oc1ccc(c(O)c1)-c1cc(=O)c2c(O)cc(O)cc2o1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima University Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin) using L-dihydroxyphenylalanine as substrate preincubated for 30 mins followed by substrate addition measure...				J Nat Prod 80: 3172-3178 (2017) Article DOI: 10.1021/acs.jnatprod.7b00453 BindingDB Entry DOI: 10.7270/Q2VD71Z4
Hiroshima University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Mus musculus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 mins				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50311785 (CHEMBL1079421 \| Phenmedipham) Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 mins				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311785 (CHEMBL1079421 \| Phenmedipham) Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH-mediated hydrolysis of [3H]AEA				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117640 (CHEMBL3613639) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Mus musculus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117639 (CHEMBL3613640) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311785 (CHEMBL1079421 \| Phenmedipham) Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117639 (CHEMBL3613640) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117640 (CHEMBL3613639) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117646 (CHEMBL3613628) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311786 (Amperozide \| CHEMBL1079935) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	455	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH-mediated hydrolysis of [3H]AEA				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460516 (CHEMBL4227539) Show SMILES Clc1cccc2c1nc(OCc1ccccc1)oc2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117638 (CHEMBL3613641) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117638 (CHEMBL3613641) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influx				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117645 (CHEMBL3613629) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117650 (CHEMBL3613638) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117652 (CHEMBL3613636) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117647 (CHEMBL3613627) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117637 (CHEMBL3613643) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117645 (CHEMBL3613629) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117646 (CHEMBL3613628) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117651 (CHEMBL3613637) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117654 (CHEMBL3613634) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311786 (Amperozide \| CHEMBL1079935) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460510 (CHEMBL4225584) Show SMILES Clc1cccc2nc(OCc3ccccc3)oc(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117644 (CHEMBL3613630) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influx				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117653 (CHEMBL3613635) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117644 (CHEMBL3613630) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460511 (CHEMBL4225103) Show SMILES Cc1cccc2nc(OCC#C)oc(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117637 (CHEMBL3613643) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50406296 (CHEMBL145012) Show SMILES O=c1oc(OCc2ccccc2)nc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117647 (CHEMBL3613627) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117641 (CHEMBL3613633) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117649 (CHEMBL3613625) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460512 (CHEMBL4225312) Show SMILES Cc1ccc2nc(OCc3ccccc3)oc(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117648 (CHEMBL3613626) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117641 (CHEMBL3613633) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460514 (CHEMBL4229256) Show SMILES Clc1cccc2nc(OCC#C)oc(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117648 (CHEMBL3613626) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50288096 (5-Chloro-2-ethoxy-benzo[d][1,3]oxazin-4-one \| CHEM...) Show SMILES CCOc1nc2cccc(Cl)c2c(=O)o1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460513 (CHEMBL4228380) Show SMILES O=c1oc(OCc2ccccc2)nc2cc3ccccc3cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117649 (CHEMBL3613625) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM26194 (4-Hydroxybenzoate, III \| 4-hydroxybenzoic acid \| C...) Show SMILES OC(=O)c1ccc(O)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima University Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cells				J Nat Prod 80: 3172-3178 (2017) Article DOI: 10.1021/acs.jnatprod.7b00453 BindingDB Entry DOI: 10.7270/Q2VD71Z4
Hiroshima University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117642 (CHEMBL3613632) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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