Found 933 hits with Last Name = 'kurose' and Initial = 'n' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659822
(N-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-3-((pyrid...)Show SMILES CC(C)Cn1c2c(COc3cccnc3)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| UniChem
| | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659957
(N-Cyclopropyl-4-hydroxy-1-neopentyl-2,8-dioxo-1,2,...)Show SMILES CC(C)(C)Cn1c2c3ccc(=O)[nH]c3nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM210898
(US9273043, A126(e))Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(C)cc2s1)c1ncc(cc1F)[C@@H](O)CO |r| Show InChI InChI=1S/C21H24FN5O3S/c1-12-3-4-16-18(7-12)31-20(24-16)25-21(30)27-6-5-26(10-13(27)2)19-15(22)8-14(9-23-19)17(29)11-28/h3-4,7-9,13,17,28-29H,5-6,10-11H2,1-2H3,(H,24,25,30)/t13-,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ... |
US Patent US9273043 (2016)
BindingDB Entry DOI: 10.7270/Q2D7998G |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM210894
(US9273043, A123(e))Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(Cl)cc2s1)c1ncc(cc1F)[C@@H](O)CO |r| Show InChI InChI=1S/C20H21ClFN5O3S/c1-11-9-26(18-14(22)6-12(8-23-18)16(29)10-28)4-5-27(11)20(30)25-19-24-15-3-2-13(21)7-17(15)31-19/h2-3,6-8,11,16,28-29H,4-5,9-10H2,1H3,(H,24,25,30)/t11-,16+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ... |
US Patent US9273043 (2016)
BindingDB Entry DOI: 10.7270/Q2D7998G |
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660316
(3-((E)-3-((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3C[C@@H]4C[C@H]3CO4)c(C)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM185339
(US9156830, I-7)Show SMILES Cc1nnc(o1)-c1cnc(C2=CCN(CC2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(Cl)c1 |t:11| Show InChI InChI=1S/C24H26ClN5O2/c1-15-28-29-22(32-15)17-13-20(25)21(26-14-17)16-9-11-30(12-10-16)23(31)27-19-7-5-18(6-8-19)24(2,3)4/h5-9,13-14H,10-12H2,1-4H3,(H,27,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SHIONOGI & CO., LTD.
US Patent
| Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect... |
US Patent US9156830 (2015)
BindingDB Entry DOI: 10.7270/Q2SN07R2 |
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659933
((R,E)-N-Cyclopropyl-7-hydroxy-4-((1-methylcyclopro...)Show SMILES C[C@@H]1COCCN1C(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC3(C)CC3)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659935
((R,E)-N-Cyclopropyl-7-hydroxy-3-(3-(3-(methoxymeth...)Show SMILES COC[C@@H]1COCCN1C(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC3(C)CC3)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660095
((R,E)-N-Cyclopropyl-7-hydroxy-4-isobutyl-3-(3-(3-(...)Show SMILES COC[C@@H]1COCCN1C(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC(C)C)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659964
(N-Cyclopropyl-9-hydroxy-6-neopentyl-2,7-dioxo-1,2,...)Show SMILES CC(C)(C)Cn1c2c3CCOC(=O)Nc3nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660080
((E)-N-Cyclopropyl-7-hydroxy-4-isobutyl-3-(3-((2-me...)Show SMILES COCCNC(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC(C)C)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660077
((E)-N-Cyclopropyl-3-(3-(1,1-dioxidothiomorpholino)...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCS(=O)(=O)CC3)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659932
((S,E)-N-Cyclopropyl-7-hydroxy-4-((1-methylcyclopro...)Show SMILES C[C@H]1COCCN1C(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC3(C)CC3)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660019
((E)-3-(3-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-3-o...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CC4CCC(C3)O4)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660060
((E)-N-Cyclopropyl-3-(3-(cyclopropyl(methyl)amino)-...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N(C)C3CC3)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659980
((S,E)-2-Amino-N-cyclopropyl-7-hydroxy-4-isobutyl-3...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOC[C@@H]3C)c(N)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659979
((E)-2-Amino-N-cyclopropyl-7-hydroxy-4-isobutyl-3-(...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOCC3)c(N)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660084
((S,E)-N-Cyclopropyl-7-hydroxy-3-(3-(2-(hydroxymeth...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCO[C@H](CO)C3)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659949
((E)-N-Cyclopropyl-7-hydroxy-4-((4-methyltetrahydro...)Show SMILES CC1(Cn2c3c(\C=C\C(=O)N4CCOCC4)cnn3c(O)c(C(=O)NC3CC3)c2=O)CCOCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM210896
(US9273043, A125(e))Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncc(cc1F)[C@@H](O)CO |r| Show InChI InChI=1S/C20H21F2N5O3S/c1-11-9-26(18-14(22)6-12(8-23-18)16(29)10-28)4-5-27(11)20(30)25-19-24-15-3-2-13(21)7-17(15)31-19/h2-3,6-8,11,16,28-29H,4-5,9-10H2,1H3,(H,24,25,30)/t11-,16+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description
pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ... |
US Patent US9273043 (2016)
BindingDB Entry DOI: 10.7270/Q2D7998G |
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660013
((E)-N6-Cyclopropyl-7-hydroxy-4-isobutyl-3-(3-morph...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOCC3)c(nn2c(O)c(C(=O)NC2CC2)c1=O)C(N)=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660318
(N-Cyclopropyl-3-((E)-3-(trans-3,4-difluoropyrrolid...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3C[C@H](F)[C@@H](F)C3)c(C)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660079
((E)-N-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-3-(3-...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCC(=O)C3)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659934
((S,E)-N-Cyclopropyl-7-hydroxy-3-(3-(3-(methoxymeth...)Show SMILES COC[C@H]1COCCN1C(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC3(C)CC3)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659981
((R,E)-2-Amino-N-cyclopropyl-7-hydroxy-4-isobutyl-3...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOC[C@H]3C)c(N)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659931
((E)-3-(3-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-3-o...)Show SMILES CC1(Cn2c3c(\C=C\C(=O)N4CC5CCC(C4)O5)cnn3c(O)c(C(=O)NC3CC3)c2=O)CC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659966
(N-Cyclopropyl-4-hydroxy-1-neopentyl-2,8-dioxo-1,2,...)Show SMILES CC(C)(C)Cn1c2c3CCC(=O)Nc3nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659930
((E)-3-(3-(3-Oxa-8-azabicyclo[3.2.1]octan-8-yl)-3-o...)Show SMILES CC1(Cn2c3c(\C=C\C(=O)N4C5CCC4COC5)cnn3c(O)c(C(=O)NC3CC3)c2=O)CC1 |THB:8:10:15.16.17:12.13| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660119
(N-Cyclopropyl-3-((E)-3-((3R,5R)-3,5-dimethylmorpho...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3[C@H](C)COC[C@H]3C)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660145
((E)-N-Cyclopropyl-7-hydroxy-2-methyl-3-(3-morpholi...)Show SMILES Cc1nn2c(O)c(C(=O)NC3CC3)c(=O)n(CC(C)(C)C)c2c1\C=C\C(=O)N1CCOCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659927
((E)-N-Cyclopropyl-4-((1-fluorocyclopropyl)methyl)-...)Show SMILES Oc1c(C(=O)NC2CC2)c(=O)n(CC2(F)CC2)c2c(\C=C\C(=O)N3CCOCC3)cnn12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659967
(N-Cyclopropyl-4-hydroxy-1-isobutyl-2,8-dioxo-1,2,7...)Show SMILES CC(C)Cn1c2c3CCC(=O)Nc3nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659965
(N-Cyclopropyl-7-hydroxy-4-neopentyl-2,5-dioxo-2,3,...)Show SMILES CC(C)(C)Cn1c2c3CC(=O)Nc3nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660244
((E)-3-(3-((Cyanomethyl)(methyl)amino)-3-oxoprop-1-...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N(C)CC#N)c(C)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660102
(3-((E)-3-((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3C[C@@H]4C[C@H]3CO4)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659784
(N6-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-N3-((tet...)Show SMILES CC(C)Cn1c2c(cnn2c(O)c(C(=O)NC2CC2)c1=O)C(=O)NCC1CCOCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660096
((E)-3-(3-(3-Oxa-8-azabicyclo[3.2.1]octan-8-yl)-3-o...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3C4CCC3COC4)cnn2c(O)c(C(=O)NC2CC2)c1=O |THB:9:11:16.17.18:13.14| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660040
((E)-3-(3-(4-Carbamoylpiperidin-1-yl)-3-oxoprop-1-e...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCC(CC3)C(N)=O)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660088
((S,E)-N-Cyclopropyl-7-hydroxy-3-(3-(3-(hydroxymeth...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOC[C@@H]3CO)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659937
(3-((E)-3-((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-...)Show SMILES CC1(Cn2c3c(\C=C\C(=O)N4C[C@H]5C[C@@H]4CO5)cnn3c(O)c(C(=O)NC3CC3)c2=O)CC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659938
(3-((E)-3-((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-...)Show SMILES Oc1c(C(=O)NC2CC2)c(=O)n(CC2(F)CC2)c2c(\C=C\C(=O)N3C[C@H]4C[C@@H]3CO4)cnn12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659974
((E)-2-Amino-N-cyclopropyl-7-hydroxy-3-(3-morpholin...)Show SMILES CC(C)(C)Cn1c2c(\C=C\C(=O)N3CCOCC3)c(N)nn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659928
((E)-N-Cyclopropyl-7-hydroxy-4-(2-methoxy-2-methylp...)Show SMILES COC(C)(C)Cn1c2c(\C=C\C(=O)N3CCOCC3)cnn2c(O)c(C(=O)NC2CC2)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659771
(N6-Cyclopropyl-7-hydroxy-4-neopentyl-5-oxo-4,5-dih...)Show SMILES CC(C)(C)Cn1c2cc(nn2c(O)c(C(=O)NC2CC2)c1=O)C(N)=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659790
(N-Cyclopropyl-7-hydroxy-4-isobutyl-3-(morpholine-4...)Show SMILES CC(C)Cn1c2c(cnn2c(O)c(C(=O)NC2CC2)c1=O)C(=O)N1CCOCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM659794
(N6-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-N3-(pyri...)Show SMILES CC(C)Cn1c2c(cnn2c(O)c(C(=O)NC2CC2)c1=O)C(=O)NCc1ncccn1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Ligand-Target Pair | |
Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660006
((E)-2-Amino-N-cyclopropyl-7-hydroxy-5-oxo-4-((tetr...)Show SMILES Nc1nn2c(O)c(C(=O)NC3CC3)c(=O)n(CC3CCOCC3)c2c1\C=C\C1CCOCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660103
((R,E)-N-Cyclopropyl-3-(3-(3-ethylmorpholino)-3-oxo...)Show SMILES CC[C@@H]1COCCN1C(=O)\C=C\c1cnn2c(O)c(C(=O)NC3CC3)c(=O)n(CC(C)C)c12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660108
((S,E)-7-Hydroxy-4-isobutyl-3-(3-morpholino-3-oxopr...)Show SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOCC3)cnn2c(O)c(C(=O)N[C@@H](C)C(F)(F)F)c1=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a |
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Sepiapterin reductase
(Homo sapiens (Human)) | BDBM660008
((E)-2-Amino-N-cyclopropyl-7-hydroxy-4-((4-methylte...)Show SMILES CC1(Cn2c3c(\C=C\C4CCOCC4)c(N)nn3c(O)c(C(=O)NC3CC3)c2=O)CCOCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a |
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