Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50274835![]() (CHEMBL511857 | trans-1-(4-(3-methoxyphenyl)cyclohe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50107249![]() (1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM21392![]() (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033843![]() (1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-yliden...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50107234![]() (1-[3-(5-Methoxy-naphthalen-1-yl)-propyl]-4-pyridin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033852![]() (1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50253281![]() (CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Binding affinity to rat cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395193![]() (CHEMBL2164330) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395191![]() (CHEMBL494675) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395187![]() (CHEMBL2164334) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395192![]() (CHEMBL2164336) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395189![]() (CHEMBL2164332) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395198![]() (CHEMBL2164329) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395203![]() (CHEMBL2164338) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395194![]() (CHEMBL2164343) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395199![]() (CHEMBL2164328) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755![]() (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395196![]() (CHEMBL2164339) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395195![]() (CHEMBL2164341) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 14.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50253281![]() (CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395193![]() (CHEMBL2164330) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395200![]() (CHEMBL2164344) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395202![]() (CHEMBL2164340) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50107245![]() (1-[4-(3-Methoxy-phenyl)-butyl]-4-pyridin-2-yl-pipe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding after 20 mins by l... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395190![]() (CHEMBL2164331) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395196![]() (CHEMBL2164339) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 31.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395188![]() (CHEMBL2164333) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 63.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395190![]() (CHEMBL2164331) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 72.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395195![]() (CHEMBL2164341) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50007407![]() (1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cells | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395205![]() (CHEMBL2164335) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395201![]() (CHEMBL2164342) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395191![]() (CHEMBL494675) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395188![]() (CHEMBL2164333) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395194![]() (CHEMBL2164343) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50001862![]() ((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 243 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cells | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50001915![]() (1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 352 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cells | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395192![]() (CHEMBL2164336) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 476 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395204![]() (CHEMBL2164337) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human cloned 5HT7 receptor | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395192![]() (CHEMBL2164336) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 438 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Antagonist activity at human 5HT7A receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation by ELISA | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50395191![]() (CHEMBL494675) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 531 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Antagonist activity at human 5HT7A receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation by ELISA | J Med Chem 55: 6375-80 (2012) Article DOI: 10.1021/jm3003679 BindingDB Entry DOI: 10.7270/Q2N87BWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50107249![]() (1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755![]() (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM21393![]() (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50274835![]() (CHEMBL511857 | trans-1-(4-(3-methoxyphenyl)cyclohe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.324 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assay | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033843![]() (1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-yliden...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.39E+3 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assay | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50107249![]() (1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assay | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755![]() (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assay | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM21393![]() (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells after 90 mins by beta-arrestin-2 recruitment assay | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50033852![]() (1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.776 | n/a | n/a | n/a | n/a |
Karolinska Institute and Karolinska University Hospital Curated by ChEMBL | Assay Description Agonist activity at human 5-HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 15 mins by EL... | Bioorg Med Chem 23: 4824-30 (2015) Article DOI: 10.1016/j.bmc.2015.05.042 BindingDB Entry DOI: 10.7270/Q21R6S8W | |||||||||||
More data for this Ligand-Target Pair |
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