Compile Data Set for Download or QSAR

Found 43 hits with Last Name = 'tricoche' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chitinase (Onchocerca volvulus)	BDBM50022832 (Rafoxanide) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Competitive inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 ...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Competitive inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 ...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50498224 (CHEMBL3577757) Show SMILES [Br-].Cc1[n+](Cc2ccc(Cl)cc2)ccc2c1[nH]c1cc(OCc3ccc(Cl)cc3)ccc21 Show InChI InChI=1S/C26H20Cl2N2O/c1-17-26-24(12-13-30(17)15-18-2-6-20(27)7-3-18)23-11-10-22(14-25(23)29-26)31-16-19-4-8-21(28)9-5-19/h2-14H,15-16H2,1H3/p+1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Competitive inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assess...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	3.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Competitive inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assess...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022832 (Rafoxanide) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022892 (CHEMBL3298112) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H12ClI2NO2/c20-13-5-1-11(2-6-13)12-3-7-15(8-4-12)23-19(25)16-9-14(21)10-17(22)18(16)24/h1-10,24H,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022890 (CHEMBL3298110) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H13I2NO2/c20-14-10-16(18(23)17(21)11-14)19(24)22-15-8-6-13(7-9-15)12-4-2-1-3-5-12/h1-11,23H,(H,22,24)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022830 (CHEMBL3298103) Show SMILES COc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H14ClI2NO3/c1-26-19-17(10-13(22)11-18(19)23)20(25)24-14-4-8-16(9-5-14)27-15-6-2-12(21)3-7-15/h2-11H,1H3,(H,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347553 (CHEMBL1801794) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(I)cc1 Show InChI InChI=1S/C13H8I3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347552 (CHEMBL391125) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C13H8BrI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022829 (CHEMBL3298102) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C19H12ClI2NO3/c20-11-1-5-14(6-2-11)26-15-7-3-13(4-8-15)23-19(25)16-9-12(21)10-17(22)18(16)24/h1-10,24H,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022834 (CHEMBL3298104) Show SMILES Clc1ccc(Oc2ccc(NC(=O)c3cc(I)cc(I)c3)cc2)cc1 Show InChI InChI=1S/C19H12ClI2NO2/c20-13-1-5-17(6-2-13)25-18-7-3-16(4-8-18)23-19(24)12-9-14(21)11-15(22)10-12/h1-11H,(H,23,24)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347551 (CHEMBL395873) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H8FI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022887 (CHEMBL3298108) Show SMILES COc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C18H13I2NO2/c1-23-17-15(9-13(19)10-16(17)20)18(22)21-14-7-6-11-4-2-3-5-12(11)8-14/h2-10H,1H3,(H,21,22)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022886 (CHEMBL3298107) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C17H11I2NO2/c18-12-8-14(16(21)15(19)9-12)17(22)20-13-6-5-10-3-1-2-4-11(10)7-13/h1-9,21H,(H,20,22)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022891 (CHEMBL3298111) Show SMILES Cc1ccc(cc1)-c1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C20H15I2NO2/c1-12-2-4-13(5-3-12)14-6-8-16(9-7-14)23-20(25)17-10-15(21)11-18(22)19(17)24/h2-11,24H,1H3,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022826 (CHEMBL3298099) Show SMILES Ic1cc(I)cc(c1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H13I2NO2/c20-14-10-13(11-15(21)12-14)19(23)22-16-6-8-18(9-7-16)24-17-4-2-1-3-5-17/h1-12H,(H,22,23)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022827 (CHEMBL3298100) Show SMILES Cc1ccc(Oc2ccc(NC(=O)c3cc(I)cc(I)c3O)cc2)cc1 Show InChI InChI=1S/C20H15I2NO3/c1-12-2-6-15(7-3-12)26-16-8-4-14(5-9-16)23-20(25)17-10-13(21)11-18(22)19(17)24/h2-11,24H,1H3,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022885 (CHEMBL3298106) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccccc2Cl)cc1 Show InChI InChI=1S/C19H12ClI2NO3/c20-15-3-1-2-4-17(15)26-13-7-5-12(6-8-13)23-19(25)14-9-11(21)10-16(22)18(14)24/h1-10,24H,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022823 (CHEMBL3297930) Show SMILES COc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C20H15I2NO3/c1-25-19-17(11-13(21)12-18(19)22)20(24)23-14-7-9-16(10-8-14)26-15-5-3-2-4-6-15/h2-12H,1H3,(H,23,24)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022888 (CHEMBL3298109) Show SMILES Ic1cc(I)cc(c1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C17H11I2NO/c18-14-7-13(8-15(19)10-14)17(21)20-16-6-5-11-3-1-2-4-12(11)9-16/h1-10H,(H,20,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50498224 (CHEMBL3577757) Show SMILES [Br-].Cc1[n+](Cc2ccc(Cl)cc2)ccc2c1[nH]c1cc(OCc3ccc(Cl)cc3)ccc21 Show InChI InChI=1S/C26H20Cl2N2O/c1-17-26-24(12-13-30(17)15-18-2-6-20(27)7-3-18)23-11-10-22(14-25(23)29-26)31-16-19-4-8-21(28)9-5-19/h2-14H,15-16H2,1H3/p+1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022828 (CHEMBL3298101) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H12FI2NO3/c20-11-1-5-14(6-2-11)26-15-7-3-13(4-8-15)23-19(25)16-9-12(21)10-17(22)18(16)24/h1-10,24H,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347554 (CHEMBL1801795) Show SMILES CC(C)c1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C16H15I2NO2/c1-9(2)10-3-5-12(6-4-10)19-16(21)13-7-11(17)8-14(18)15(13)20/h3-9,20H,1-2H3,(H,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347549 (CHEMBL482487) Show SMILES Cc1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C14H11I2NO2/c1-8-2-4-10(5-3-8)17-14(19)11-6-9(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022842 (CHEMBL3298105) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2cccc(Cl)c2)cc1 Show InChI InChI=1S/C19H12ClI2NO3/c20-11-2-1-3-15(8-11)26-14-6-4-13(5-7-14)23-19(25)16-9-12(21)10-17(22)18(16)24/h1-10,24H,(H,23,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022824 (CHEMBL3298097) Show SMILES CN(C(=O)c1cc(I)cc(I)c1O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C20H15I2NO3/c1-23(20(25)17-11-13(21)12-18(22)19(17)24)14-7-9-16(10-8-14)26-15-5-3-2-4-6-15/h2-12,24H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022822 (CHEMBL483713) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H13I2NO3/c20-12-10-16(18(23)17(21)11-12)19(24)22-13-6-8-15(9-7-13)25-14-4-2-1-3-5-14/h1-11,23H,(H,22,24)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50498228 (CHEMBL3577758) Show SMILES Cc1nccc2c3ccc(OCc4ccc(Cl)cc4)cc3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C26H20Cl2N2O/c1-17-26-24(12-13-29-17)23-11-10-22(31-16-19-4-8-21(28)9-5-19)14-25(23)30(26)15-18-2-6-20(27)7-3-18/h2-14H,15-16H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50498225 (CHEMBL3577754) Show SMILES [Br-].COc1ccc2c(c1)[nH]c1c(C)[n+](Cc3ccc(Cl)cc3)ccc21 Show InChI InChI=1S/C20H17ClN2O/c1-13-20-18(17-8-7-16(24-2)11-19(17)22-20)9-10-23(13)12-14-3-5-15(21)6-4-14/h3-11H,12H2,1-2H3/p+1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50498227 (CHEMBL3577753) Show SMILES [Br-].COc1ccc2c(c1)[nH]c1c(C)[n+](CC3CC3)ccc21 Show InChI InChI=1S/C17H18N2O/c1-11-17-15(7-8-19(11)10-12-3-4-12)14-6-5-13(20-2)9-16(14)18-17/h5-9,12H,3-4,10H2,1-2H3/p+1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50022825 (CHEMBL3298098) Show SMILES COc1c(I)cc(I)cc1C(=O)N(C)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C21H17I2NO3/c1-24(21(25)18-12-14(22)13-19(23)20(18)26-2)15-8-10-17(11-9-15)27-16-6-4-3-5-7-16/h3-13H,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347555 (3,5-Dibromo-2-hydroxy-N-(4-methoxyphenyl)benzamide...) Show SMILES COc1ccc(NC(=O)c2cc(Br)cc(Br)c2O)cc1 Show InChI InChI=1S/C14H11Br2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347548 (CHEMBL237819) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H8ClI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	7.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50498226 (Harmol) Show SMILES Cc1[nH]ccc2c3ccc(=O)cc3[nH]c12 Show InChI InChI=1S/C12H10N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-6,13-14H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50013786 (1-Methyl-9H-beta-carboline | 1-Methyl-9H-beta-carb...) Show SMILES Cc1nccc2c3ccccc3[nH]c12 Show InChI InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50013811 (9H-beta-Carboline | 9H-pyrido[3,4-b]indole | CHEMB...) Show SMILES c1ccc2c(c1)[nH]c1cnccc21 Show InChI InChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347550 (CHEMBL484912) Show SMILES COc1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C14H11I2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50065988 (3,5-Dichloro-N-(4-chloro-phenyl)-2-hydroxy-benzami...) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H8Cl3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair