BindingDB PrimarySearch

Found 48 hits with Last Name = 'pendleton' and Initial = 'rg'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) Show SMILES Clc1ccc2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline& French Laboratories Curated by ChEMBL					Assay Description Binding affinity for phenylethanolamine N-methyl-transferase was determined.				J Med Chem 32: 1566-71 (1989) BindingDB Entry DOI: 10.7270/Q2QZ2BJV
Smith Kline& French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) Show SMILES Clc1ccc2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phenylethanolamine N-methyltransferase (Bos taurus (bovine))	BDBM50018237 (6,7,8,9-Tetrahydro-3-thia-1,2,8-triaza-cyclopenta[...) Show SMILES C1Cc2ccc3snnc3c2CN1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline& French Laboratories Curated by ChEMBL					Assay Description Binding affinity for phenylethanolamine N-methyl-transferase was determined.				J Med Chem 32: 1566-71 (1989) BindingDB Entry DOI: 10.7270/Q2QZ2BJV
Smith Kline& French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029108 (6,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline \| ...) Show SMILES Clc1cc2CCNCc2c(Cl)c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029102 (7-Chloro-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL1...) Show SMILES Clc1ccc2CCNCc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029107 (8-Chloro-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL1...) Show SMILES Clc1cccc2CCNCc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029101 (5,6,7,8-Tetrachloro-1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Clc1c(Cl)c(Cl)c2CNCCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029099 (5,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline \| ...) Show SMILES Clc1cc(Cl)c2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) Show SMILES Clc1ccc2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) Show SMILES Clc1ccc2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028902 (7,8-dichloro-2-[2-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028908 (7,8-dichloro-2-[4-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029108 (6,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline \| ...) Show SMILES Clc1cc2CCNCc2c(Cl)c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029102 (7-Chloro-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL1...) Show SMILES Clc1ccc2CCNCc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029107 (8-Chloro-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL1...) Show SMILES Clc1cccc2CCNCc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029101 (5,6,7,8-Tetrachloro-1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Clc1c(Cl)c(Cl)c2CNCCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028903 (7,8-dichloro-2-[3-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029099 (5,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline \| ...) Show SMILES Clc1cc(Cl)c2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potency				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029106 (2,3-Dichloro-benzylamine \| CHEMBL13165) Show SMILES NCc1cccc(Cl)c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028910 (7,8-dichloro-2-[6-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028914 (7,8-dichloro-2-[7-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028911 (7,8-dichloro-2-[8-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028909 (2-(7,8-Dichloro-3,4-dihydro-1H-isoquinolin-2-yl)-e...) Show SMILES NCCN1CCc2ccc(Cl)c(Cl)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028901 (7,8-Dichloro-2-ethyl-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES CCN1CCc2ccc(Cl)c(Cl)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028913 (7,8-Dichloro-2-propyl-1,2,3,4-tetrahydro-isoquinol...) Show SMILES CCCN1CCc2ccc(Cl)c(Cl)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028912 (2-Benzyl-7,8-dichloro-1,2,3,4-tetrahydro-isoquinol...) Show SMILES Clc1ccc2CCN(Cc3ccccc3)Cc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM12584 ((3-chlorophenyl)methanamine \| 1-(3-CHLOROPHENYL)ME...) Show SMILES NCc1cccc(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) Show SMILES Clc1ccc2CCNCc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against human phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028906 (7,8-dichloro-2-[5-(7,8-dichloro-1,2,3,4-tetrahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029105 (2-(3,4,-dichlorophenyl)ethylamine \| 2-(3,4-Dichlor...) Show SMILES NCCc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029104 (2-Chloro-benzylamine \| CHEMBL12712) Show SMILES NCc1ccccc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028905 (7,8-Dichloro-2-(6-phenyl-hexyl)-1,2,3,4-tetrahydro...) Show SMILES Clc1ccc2CCN(CCCCCCc3ccccc3)Cc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029103 (2-(3-Chloro-phenyl)-1-methyl-ethylamine \| CHEMBL14...) Show SMILES CC(N)Cc1cccc(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028904 (2-(6-Bromo-hexyl)-7,8-dichloro-1,2,3,4-tetrahydro-...) Show SMILES Clc1ccc2CCN(CCCCCCBr)Cc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50028907 (6-(7,8-Dichloro-3,4-dihydro-1H-isoquinolin-2-yl)-h...) Show SMILES OCCCCCCN1CCc2ccc(Cl)c(Cl)c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferase				J Med Chem 24: 756-9 (1981) BindingDB Entry DOI: 10.7270/Q2DZ08VH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine \| CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026774 (7,10-Dimethoxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[...) Show SMILES COc1ccc(OC)c2C3CCCN[C@@H]3CCc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM23981 ((2S)-1,2,3,4-Tetrahydro-naphthalen-2-ylamine \| 1,2...) Show SMILES NC1CCc2ccccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026775 (4,7-Dimethoxy-indan-2-ylamine \| CHEMBL284307) Show SMILES COc1ccc(OC)c2CC(N)Cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026783 (5,8-Dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ylam...) Show SMILES COc1ccc(OC)c2CC(N)CCc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026782 (5,8-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline \| CH...) Show SMILES COc1ccc(OC)c2CNCCc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026781 (3,6-Dimethoxy-tricyclo[6.2.2.02,7]dodeca-2,4,6-t...) Show SMILES COc1ccc(OC)c2C3CCC(C[C@@H]3N)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026779 (7,10-Dimethoxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[...) Show SMILES COc1ccc(OC)c2C3CCCN[C@H]3CCc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026780 (1,4-Dimethoxy-6,7,8,9-tetrahydro-5H-benzocyclohept...) Show SMILES COc1ccc(OC)c2CC(N)CCCc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026778 (2-(2,5-Dimethoxy-phenyl)-ethylamine \| 2-(2,5-dimet...) Show SMILES COc1ccc(OC)c(CCN)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026773 (3,6-Dimethoxy-tricyclo[6.2.2.02,7]dodeca-2,4,6-t...) Show SMILES COc1ccc(OC)c2C3CCC(C[C@H]3N)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026777 (2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol \| 2-A...) Show SMILES COc1ccc(OC)c(c1)C(O)C(C)N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50026776 (2,5-Dimethoxy-1,1a,6,6a-tetrahydro-cyclopropa[a]in...) Show SMILES COc1ccc(OC)c2C3[C@H](N)C3Cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor agonist activity in rabbit ear artery				J Med Chem 24: 1432-7 (1982) BindingDB Entry DOI: 10.7270/Q2XW4KB0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair