Compile Data Set for Download or QSAR

Found 46 hits with Last Name = 'riggs' and Initial = 'rm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50001888 ((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...) Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.15	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.15	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010684 ((6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010687 (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinoline-8,9...) Show SMILES Oc1cc2CC[C@H]3NCCC[C@@H]3c2cc1O Show InChI InChI=1S/C13H17NO2/c15-12-6-8-3-4-11-9(2-1-5-14-11)10(8)7-13(12)16/h6-7,9,11,14-16H,1-5H2/t9-,11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010690 (6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanth...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C18H19NO2/c1-19-10-12-4-2-3-5-13(12)18-14-9-17(21)16(20)8-11(14)6-7-15(18)19/h2-5,8-9,15,18,20-21H,6-7,10H2,1H3/t15-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM84637 (CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r| Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035647 ((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1ccc2CC[C@H]3NCc4ccccc4[C@@H]3c2c1 Show InChI InChI=1S/C17H17NO/c19-13-7-5-11-6-8-16-17(15(11)9-13)14-4-2-1-3-12(14)10-18-16/h1-5,7,9,16-19H,6,8,10H2/t16-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035651 ((6aR,12bS)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 Show InChI InChI=1S/C18H19NO/c1-19-11-13-4-2-3-5-15(13)18-16-10-14(20)8-6-12(16)7-9-17(18)19/h2-6,8,10,17-18,20H,7,9,11H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010689 ((S)-4-(4,5,6,7-Tetrahydro-thieno[2,3-c]pyridin-4-y...) Show SMILES Oc1ccc(cc1O)[C@@H]1CNCc2sccc12 Show InChI InChI=1S/C13H13NO2S/c15-11-2-1-8(5-12(11)16)10-6-14-7-13-9(10)3-4-17-13/h1-5,10,14-16H,6-7H2/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035644 ((6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1c(O)c(O)ccc21 Show InChI InChI=1S/C18H19NO2/c1-19-10-11-4-2-3-5-12(11)17-13-7-9-16(20)18(21)14(13)6-8-15(17)19/h2-5,7,9,15,17,20-21H,6,8,10H2,1H3/t15-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010690 (6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanth...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C18H19NO2/c1-19-10-12-4-2-3-5-13(12)18-14-9-17(21)16(20)8-11(14)6-7-15(18)19/h2-5,8-9,15,18,20-21H,6-7,10H2,1H3/t15-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035649 ((6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 Show InChI InChI=1S/C20H23NO/c1-2-11-21-13-15-5-3-4-6-17(15)20-18-12-16(22)9-7-14(18)8-10-19(20)21/h3-7,9,12,19-20,22H,2,8,10-11,13H2,1H3/t19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010689 ((S)-4-(4,5,6,7-Tetrahydro-thieno[2,3-c]pyridin-4-y...) Show SMILES Oc1ccc(cc1O)[C@@H]1CNCc2sccc12 Show InChI InChI=1S/C13H13NO2S/c15-11-2-1-8(5-12(11)16)10-6-14-7-13-9(10)3-4-17-13/h1-5,10,14-16H,6-7H2/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010688 (6-Benzylamino-5,6,7,8-tetrahydro-naphthalene-2,3-d...) Show SMILES Oc1cc2CCC(Cc2cc1O)NCc1ccccc1 Show InChI InChI=1S/C17H19NO2/c19-16-9-13-6-7-15(8-14(13)10-17(16)20)18-11-12-4-2-1-3-5-12/h1-5,9-10,15,18-20H,6-8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035645 ((6aR,12bS)-10-Bromo-6-methyl-5,6,6a,7,8,12b-hexahy...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(Br)c(O)cc21 Show InChI InChI=1S/C18H18BrNO/c1-20-10-12-4-2-3-5-13(12)18-14-9-17(21)15(19)8-11(14)6-7-16(18)20/h2-5,8-9,16,18,21H,6-7,10H2,1H3/t16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	322	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035651 ((6aR,12bS)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 Show InChI InChI=1S/C18H19NO/c1-19-11-13-4-2-3-5-15(13)18-16-10-14(20)8-6-12(16)7-9-17(18)19/h2-6,8,10,17-18,20H,7,9,11H2,1H3/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035649 ((6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 Show InChI InChI=1S/C20H23NO/c1-2-11-21-13-15-5-3-4-6-17(15)20-18-12-16(22)9-7-14(18)8-10-19(20)21/h3-7,9,12,19-20,22H,2,8,10-11,13H2,1H3/t19-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	529	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035650 ((6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1cccc2[C@@H]3[C@@H](CCc12)NCc1ccccc31 Show InChI InChI=1S/C17H17NO/c19-16-7-3-6-14-13(16)8-9-15-17(14)12-5-2-1-4-11(12)10-18-15/h1-7,15,17-19H,8-10H2/t15-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	532	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035647 ((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1ccc2CC[C@H]3NCc4ccccc4[C@@H]3c2c1 Show InChI InChI=1S/C17H17NO/c19-13-7-5-11-6-8-16-17(15(11)9-13)14-4-2-1-3-12(14)10-18-16/h1-5,7,9,16-19H,6,8,10H2/t16-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010684 ((6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	651	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50035644 ((6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1c(O)c(O)ccc21 Show InChI InChI=1S/C18H19NO2/c1-19-10-11-4-2-3-5-12(11)17-13-7-9-16(20)18(21)14(13)6-8-15(17)19/h2-5,7,9,15,17,20-21H,6,8,10H2,1H3/t15-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	955	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50035648 ((R)-6-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalen...) Show SMILES NC1CCc2cc(O)c(O)cc2[C@H]1c1ccccc1 Show InChI InChI=1S/C16H17NO2/c17-13-7-6-11-8-14(18)15(19)9-12(11)16(13)10-4-2-1-3-5-10/h1-5,8-9,13,16,18-19H,6-7,17H2/t13?,16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity towards Dopamine receptor D1				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50035648 ((R)-6-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalen...) Show SMILES NC1CCc2cc(O)c(O)cc2[C@H]1c1ccccc1 Show InChI InChI=1S/C16H17NO2/c17-13-7-6-11-8-14(18)15(19)9-12(11)16(13)10-4-2-1-3-5-10/h1-5,8-9,13,16,18-19H,6-7,17H2/t13?,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro receptor binding affinity against Dopamine receptor D2				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035643 ((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1cccc2[C@H]3[C@@H](CCc12)NCc1ccccc31 Show InChI InChI=1S/C17H17NO/c19-16-7-3-6-14-13(16)8-9-15-17(14)12-5-2-1-4-11(12)10-18-15/h1-7,15,17-19H,8-10H2/t15-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035643 ((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1cccc2[C@H]3[C@@H](CCc12)NCc1ccccc31 Show InChI InChI=1S/C17H17NO/c19-16-7-3-6-14-13(16)8-9-15-17(14)12-5-2-1-4-11(12)10-18-15/h1-7,15,17-19H,8-10H2/t15-,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035645 ((6aR,12bS)-10-Bromo-6-methyl-5,6,6a,7,8,12b-hexahy...) Show SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(Br)c(O)cc21 Show InChI InChI=1S/C18H18BrNO/c1-20-10-12-4-2-3-5-13(12)18-14-9-17(21)15(19)8-11(14)6-7-16(18)20/h2-5,8-9,16,18,21H,6-7,10H2,1H3/t16-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010687 (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinoline-8,9...) Show SMILES Oc1cc2CC[C@H]3NCCC[C@@H]3c2cc1O Show InChI InChI=1S/C13H17NO2/c15-12-6-8-3-4-11-9(2-1-5-14-11)10(8)7-13(12)16/h6-7,9,11,14-16H,1-5H2/t9-,11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010685 ((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010685 ((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50010688 (6-Benzylamino-5,6,7,8-tetrahydro-naphthalene-2,3-d...) Show SMILES Oc1cc2CCC(Cc2cc1O)NCc1ccccc1 Show InChI InChI=1S/C17H19NO2/c19-16-9-13-6-7-15(8-14(13)10-17(16)20)18-11-12-4-2-1-3-5-12/h1-5,9-10,15,18-20H,6-8,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035650 ((6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1cccc2[C@@H]3[C@@H](CCc12)NCc1ccccc31 Show InChI InChI=1S/C17H17NO/c19-16-7-3-6-14-13(16)8-9-15-17(14)12-5-2-1-4-11(12)10-18-15/h1-7,15,17-19H,8-10H2/t15-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035646 ((6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1ccc2CC[C@H]3NCc4ccccc4[C@H]3c2c1 Show InChI InChI=1S/C17H17NO/c19-13-7-5-11-6-8-16-17(15(11)9-13)14-4-2-1-3-12(14)10-18-16/h1-5,7,9,16-19H,6,8,10H2/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035646 ((6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1ccc2CC[C@H]3NCc4ccccc4[C@H]3c2c1 Show InChI InChI=1S/C17H17NO/c19-13-7-5-11-6-8-16-17(15(11)9-13)14-4-2-1-3-12(14)10-18-16/h1-5,7,9,16-19H,6,8,10H2/t16-,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM84637 (CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r| Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50010589 (6,7-Dihydro-5H-indeno[5,6-d][1,3]dioxol-6-ylamine ...) Show SMILES NC1Cc2cc3OCOc3cc2C1 Show InChI InChI=1S/C10H11NO2/c11-8-1-6-3-9-10(13-5-12-9)4-7(6)2-8/h3-4,8H,1-2,5,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	0.127	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was determined towards serotonin uptake site in presence of [3H]-paroxetine radioligand in rat hippocampal homogenate				J Med Chem 33: 703-10 (1990) BindingDB Entry DOI: 10.7270/Q26W992G
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50010589 (6,7-Dihydro-5H-indeno[5,6-d][1,3]dioxol-6-ylamine ...) Show SMILES NC1Cc2cc3OCOc3cc2C1 Show InChI InChI=1S/C10H11NO2/c11-8-1-6-3-9-10(13-5-12-9)4-7(6)2-8/h3-4,8H,1-2,5,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	0.104	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was determined towards serotonin uptake site in presence of [3H]-paroxetine radioligand in rat brain cortical homogenate				J Med Chem 33: 703-10 (1990) BindingDB Entry DOI: 10.7270/Q26W992G
					More data for this Ligand-Target Pair