Compile Data Set for Download or QSAR

Found 64 hits with Last Name = 'sprenger' and Initial = 'rr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450263 (CHEMBL4176503) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C22H19ClN2O4S/c1-12-19(13(2)29-24-12)14-7-9-15(10-8-14)20(26)25-18(22(27)28)11-30-21(25)16-5-3-4-6-17(16)23/h3-10,18,21H,11H2,1-2H3,(H,27,28)/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450265 (CHEMBL4170748) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-9-5-3-6-17(21)15-10-12-16(13-11-15)22(27)26-20(24(28)29)14-31-23(26)18-7-2-4-8-19(18)25/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	339	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450273 (CHEMBL4168456) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C23H21ClN2O4/c1-13-21(14(2)30-25-13)15-7-9-16(10-8-15)22(27)26-19(11-12-20(26)23(28)29)17-5-3-4-6-18(17)24/h3-10,19-20H,11-12H2,1-2H3,(H,28,29)/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM403752 ((2S,5R)-5-(2-chlorophenyl)-1-(2'-methoxy-[1,1'-bip...) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O Show InChI InChI=1S/C25H22ClNO4/c1-31-23-9-5-3-6-18(23)16-10-12-17(13-11-16)24(28)27-21(14-15-22(27)25(29)30)19-7-2-4-8-20(19)26/h2-13,21-22H,14-15H2,1H3,(H,29,30)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450268 (CHEMBL4167577) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)-c1ccccc1)c1ccccc1Cl |r| Show InChI InChI=1S/C23H18ClNO3S/c24-19-9-5-4-8-18(19)22-25(20(14-29-22)23(27)28)21(26)17-12-10-16(11-13-17)15-6-2-1-3-7-15/h1-13,20,22H,14H2,(H,27,28)/t20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	977	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450272 (CHEMBL4159019) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H21NO4S/c1-29-21-10-6-5-9-19(21)16-11-13-17(14-12-16)22(26)25-20(24(27)28)15-30-23(25)18-7-3-2-4-8-18/h2-14,20,23H,15H2,1H3,(H,27,28)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450264 (CHEMBL4175033) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H20N2O4S/c1-13-19(14(2)28-23-13)15-8-10-16(11-9-15)20(25)24-18(22(26)27)12-29-21(24)17-6-4-3-5-7-17/h3-11,18,21H,12H2,1-2H3,(H,26,27)/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450265 (CHEMBL4170748) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-9-5-3-6-17(21)15-10-12-16(13-11-15)22(27)26-20(24(28)29)14-31-23(26)18-7-2-4-8-19(18)25/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450266 (CHEMBL4162808) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1cccc(Cl)c1)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-8-3-2-7-19(21)15-9-11-16(12-10-15)22(27)26-20(24(28)29)14-31-23(26)17-5-4-6-18(25)13-17/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450267 (CHEMBL4169673) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C23H20N2O4S/c1-29-20-8-3-2-6-17(20)15-9-11-16(12-10-15)21(26)25-19(23(27)28)14-30-22(25)18-7-4-5-13-24-18/h2-13,19,22H,14H2,1H3,(H,27,28)/t19-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450268 (CHEMBL4167577) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)-c1ccccc1)c1ccccc1Cl |r| Show InChI InChI=1S/C23H18ClNO3S/c24-19-9-5-4-8-18(19)22-25(20(14-29-22)23(27)28)21(26)17-12-10-16(11-13-17)15-6-2-1-3-7-15/h1-13,20,22H,14H2,(H,27,28)/t20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450269 (CHEMBL4177359) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)-c1ccc(cc1)C#N)c1ccccc1Cl |r| Show InChI InChI=1S/C24H17ClN2O3S/c25-20-4-2-1-3-19(20)23-27(21(14-31-23)24(29)30)22(28)18-11-9-17(10-12-18)16-7-5-15(13-26)6-8-16/h1-12,21,23H,14H2,(H,29,30)/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450270 (CHEMBL4175443) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)C#Cc1ccccc1)c1ccccc1Cl |r| Show InChI InChI=1S/C25H18ClNO3S/c26-21-9-5-4-8-20(21)24-27(22(16-31-24)25(29)30)23(28)19-14-12-18(13-15-19)11-10-17-6-2-1-3-7-17/h1-9,12-15,22,24H,16H2,(H,29,30)/t22-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450271 (CHEMBL4167161) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1C#C)C(O)=O |r| Show InChI InChI=1S/C24H20N2O4S/c1-4-16-7-5-6-8-19(16)23-26(20(13-31-23)24(28)29)22(27)18-11-9-17(10-12-18)21-14(2)25-30-15(21)3/h1,5-12,20,23H,13H2,2-3H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50032334 (CHEMBL3353541) Show SMILES C[C@@]1(CCN1C(=O)c1csc2ccccc12)C(=O)N(CCCC(O)=O)Cc1cccc(Cl)c1 |r| Show InChI InChI=1S/C25H25ClN2O4S/c1-25(11-13-28(25)23(31)20-16-33-21-9-3-2-8-19(20)21)24(32)27(12-5-10-22(29)30)15-17-6-4-7-18(26)14-17/h2-4,6-9,14,16H,5,10-13,15H2,1H3,(H,29,30)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM403752 ((2S,5R)-5-(2-chlorophenyl)-1-(2'-methoxy-[1,1'-bip...) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O Show InChI InChI=1S/C25H22ClNO4/c1-31-23-9-5-3-6-18(23)16-10-12-17(13-11-16)24(28)27-21(14-15-22(27)25(29)30)19-7-2-4-8-20(19)26/h2-13,21-22H,14-15H2,1H3,(H,29,30)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	525	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450265 (CHEMBL4170748) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-9-5-3-6-17(21)15-10-12-16(13-11-15)22(27)26-20(24(28)29)14-31-23(26)18-7-2-4-8-19(18)25/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450274 (CHEMBL4167352) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-5-3-2-4-19(21)15-6-8-16(9-7-15)22(27)26-20(24(28)29)14-31-23(26)17-10-12-18(25)13-11-17/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450275 (CHEMBL4159447) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Br)C(O)=O |r| Show InChI InChI=1S/C24H20BrNO4S/c1-30-21-9-5-3-6-17(21)15-10-12-16(13-11-15)22(27)26-20(24(28)29)14-31-23(26)18-7-2-4-8-19(18)25/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450272 (CHEMBL4159019) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H21NO4S/c1-29-21-10-6-5-9-19(21)16-11-13-17(14-12-16)22(26)25-20(24(27)28)15-30-23(25)18-7-3-2-4-8-18/h2-14,20,23H,15H2,1H3,(H,27,28)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	933	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450276 (CHEMBL4174384) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccco1)C(O)=O |r| Show InChI InChI=1S/C22H19NO5S/c1-27-18-6-3-2-5-16(18)14-8-10-15(11-9-14)20(24)23-17(22(25)26)13-29-21(23)19-7-4-12-28-19/h2-12,17,21H,13H2,1H3,(H,25,26)/t17-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450268 (CHEMBL4167577) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)-c1ccccc1)c1ccccc1Cl |r| Show InChI InChI=1S/C23H18ClNO3S/c24-19-9-5-4-8-18(19)22-25(20(14-29-22)23(27)28)21(26)17-12-10-16(11-13-17)15-6-2-1-3-7-15/h1-13,20,22H,14H2,(H,27,28)/t20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Mus musculus)	BDBM50450263 (CHEMBL4176503) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C22H19ClN2O4S/c1-12-19(13(2)29-24-12)14-7-9-15(10-8-14)20(26)25-18(22(27)28)11-30-21(25)16-5-3-4-6-17(16)23/h3-10,18,21H,11H2,1-2H3,(H,27,28)/t18-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	363	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at mouse FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Free fatty acid receptor 2 (Mus musculus)	BDBM50450263 (CHEMBL4176503) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C22H19ClN2O4S/c1-12-19(13(2)29-24-12)14-7-9-15(10-8-14)20(26)25-18(22(27)28)11-30-21(25)16-5-3-4-6-17(16)23/h3-10,18,21H,11H2,1-2H3,(H,27,28)/t18-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at FFA2R in mouse mature adipocytes assessed as inhibition of isoproterenol-induced glycerol production				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Free fatty acid receptor 2 (Mus musculus)	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at FFA2R in mouse mature adipocytes assessed as inhibition of isoproterenol-induced glycerol production				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450277 (CHEMBL4170955) Show SMILES COc1cccc(c1F)-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C24H19ClFNO4S/c1-31-20-8-4-6-16(21(20)26)14-9-11-15(12-10-14)22(28)27-19(24(29)30)13-32-23(27)17-5-2-3-7-18(17)25/h2-12,19,23H,13H2,1H3,(H,29,30)/t19-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.12E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450278 (CHEMBL4160351) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-18-12-10-16(11-13-18)15-6-8-17(9-7-15)22(27)26-21(24(28)29)14-31-23(26)19-4-2-3-5-20(19)25/h2-13,21,23H,14H2,1H3,(H,28,29)/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450279 (CHEMBL4169498) Show SMILES CC(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C25H20ClNO4S/c1-15(28)16-6-8-17(9-7-16)18-10-12-19(13-11-18)23(29)27-22(25(30)31)14-32-24(27)20-4-2-3-5-21(20)26/h2-13,22,24H,14H2,1H3,(H,30,31)/t22-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450269 (CHEMBL4177359) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)-c1ccc(cc1)C#N)c1ccccc1Cl |r| Show InChI InChI=1S/C24H17ClN2O3S/c25-20-4-2-1-3-19(20)23-27(21(14-31-23)24(29)30)22(28)18-11-9-17(10-12-18)16-7-5-15(13-26)6-8-16/h1-12,21,23H,14H2,(H,29,30)/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450280 (CHEMBL4171999) Show SMILES Cc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO3S/c1-15-6-2-3-7-18(15)16-10-12-17(13-11-16)22(27)26-21(24(28)29)14-30-23(26)19-8-4-5-9-20(19)25/h2-13,21,23H,14H2,1H3,(H,28,29)/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450281 (CHEMBL4164813) Show SMILES Cc1ccc(s1)-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C22H18ClNO3S2/c1-13-6-11-19(29-13)14-7-9-15(10-8-14)20(25)24-18(22(26)27)12-28-21(24)16-4-2-3-5-17(16)23/h2-11,18,21H,12H2,1H3,(H,26,27)/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.79E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450270 (CHEMBL4175443) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)C#Cc1ccccc1)c1ccccc1Cl |r| Show InChI InChI=1S/C25H18ClNO3S/c26-21-9-5-4-8-20(21)24-27(22(16-31-24)25(29)30)23(28)19-14-12-18(13-15-19)11-10-17-6-2-1-3-7-17/h1-9,12-15,22,24H,16H2,(H,29,30)/t22-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450282 (CHEMBL4165226) Show SMILES Cn1nccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C21H18ClN3O3S/c1-24-17(10-11-23-24)13-6-8-14(9-7-13)19(26)25-18(21(27)28)12-29-20(25)15-4-2-3-5-16(15)22/h2-11,18,20H,12H2,1H3,(H,27,28)/t18-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	214	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450264 (CHEMBL4175033) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H20N2O4S/c1-13-19(14(2)28-23-13)15-8-10-16(11-9-15)20(25)24-18(22(26)27)12-29-21(24)17-6-4-3-5-7-17/h3-11,18,21H,12H2,1-2H3,(H,26,27)/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450271 (CHEMBL4167161) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1C#C)C(O)=O |r| Show InChI InChI=1S/C24H20N2O4S/c1-4-16-7-5-6-8-19(16)23-26(20(13-31-23)24(28)29)22(27)18-11-9-17(10-12-18)21-14(2)25-30-15(21)3/h1,5-12,20,23H,13H2,2-3H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450273 (CHEMBL4168456) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C23H21ClN2O4/c1-13-21(14(2)30-25-13)15-7-9-16(10-8-15)22(27)26-19(11-12-20(26)23(28)29)17-5-3-4-6-18(17)24/h3-10,19-20H,11-12H2,1-2H3,(H,28,29)/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	151	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450281 (CHEMBL4164813) Show SMILES Cc1ccc(s1)-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C22H18ClNO3S2/c1-13-6-11-19(29-13)14-7-9-15(10-8-14)20(25)24-18(22(26)27)12-28-21(24)16-4-2-3-5-17(16)23/h2-11,18,21H,12H2,1H3,(H,26,27)/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.12E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450261 (CHEMBL4173130) Show SMILES COc1ccccc1C#Cc1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C26H20ClNO4S/c1-32-23-9-5-2-6-18(23)13-10-17-11-14-19(15-12-17)24(29)28-22(26(30)31)16-33-25(28)20-7-3-4-8-21(20)27/h2-9,11-12,14-15,22,25H,16H2,1H3,(H,30,31)/t22-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450282 (CHEMBL4165226) Show SMILES Cn1nccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C21H18ClN3O3S/c1-24-17(10-11-23-24)13-6-8-14(9-7-13)19(26)25-18(21(27)28)12-29-20(25)15-4-2-3-5-16(15)22/h2-11,18,20H,12H2,1H3,(H,27,28)/t18-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	977	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450263 (CHEMBL4176503) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C22H19ClN2O4S/c1-12-19(13(2)29-24-12)14-7-9-15(10-8-14)20(26)25-18(22(27)28)11-30-21(25)16-5-3-4-6-17(16)23/h3-10,18,21H,11H2,1-2H3,(H,27,28)/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450283 (CHEMBL4168646) Show SMILES OC(=O)[C@@H]1CS[C@@H](N1C(=O)c1ccc(cc1)-c1c(onc1-c1ccccc1)C1CC1)c1ccccc1Cl |r| Show InChI InChI=1S/C29H23ClN2O4S/c30-22-9-5-4-8-21(22)28-32(23(16-37-28)29(34)35)27(33)20-14-10-17(11-15-20)24-25(18-6-2-1-3-7-18)31-36-26(24)19-12-13-19/h1-11,14-15,19,23,28H,12-13,16H2,(H,34,35)/t23-,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450262 (CHEMBL4171813) Show SMILES COc1ccccc1[C@H]1SC[C@H](N1C(=O)c1ccc(cc1)-c1c(C)noc1C)C(O)=O |r| Show InChI InChI=1S/C23H22N2O5S/c1-13-20(14(2)30-24-13)15-8-10-16(11-9-15)21(26)25-18(23(27)28)12-31-22(25)17-6-4-5-7-19(17)29-3/h4-11,18,22H,12H2,1-3H3,(H,27,28)/t18-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450286 (CHEMBL4161202) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C21H19N3O4S/c1-12-18(13(2)28-23-12)14-6-8-15(9-7-14)19(25)24-17(21(26)27)11-29-20(24)16-5-3-4-10-22-16/h3-10,17,20H,11H2,1-2H3,(H,26,27)/t17-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.55E+4	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450273 (CHEMBL4168456) Show SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C23H21ClN2O4/c1-13-21(14(2)30-25-13)15-7-9-16(10-8-15)22(27)26-19(11-12-20(26)23(28)29)17-5-3-4-6-18(17)24/h3-10,19-20H,11-12H2,1-2H3,(H,28,29)/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305974 ((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...) Show SMILES CC(C)[C@H](C(=O)Nc1nccs1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	417	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450289 (CHEMBL4172928) Show SMILES OC(=O)C[C@@H](Cc1ccccc1)C(=O)N(C1CC1)c1nc(cs1)-c1cc(Cl)ccc1Cl |r| Show InChI InChI=1S/C23H20Cl2N2O3S/c24-16-6-9-19(25)18(12-16)20-13-31-23(26-20)27(17-7-8-17)22(30)15(11-21(28)29)10-14-4-2-1-3-5-14/h1-6,9,12-13,15,17H,7-8,10-11H2,(H,28,29)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	209	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM403752 ((2S,5R)-5-(2-chlorophenyl)-1-(2'-methoxy-[1,1'-bip...) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O Show InChI InChI=1S/C25H22ClNO4/c1-31-23-9-5-3-6-18(23)16-10-12-17(13-11-16)24(28)27-21(14-15-22(27)25(29)30)19-7-2-4-8-20(19)26/h2-13,21-22H,14-15H2,1H3,(H,29,30)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450266 (CHEMBL4162808) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1cccc(Cl)c1)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-8-3-2-7-19(21)15-9-11-16(12-10-15)22(27)26-20(24(28)29)14-31-23(26)17-5-4-6-18(25)13-17/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450274 (CHEMBL4167352) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C24H20ClNO4S/c1-30-21-5-3-2-4-19(21)15-6-8-16(9-7-15)22(27)26-20(24(28)29)14-31-23(26)17-10-12-18(25)13-11-17/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50450275 (CHEMBL4159447) Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Br)C(O)=O |r| Show InChI InChI=1S/C24H20BrNO4S/c1-30-21-9-5-3-6-17(21)15-10-12-16(13-11-15)22(27)26-20(24(28)29)14-31-23(26)18-7-2-4-8-19(18)25/h2-13,20,23H,14H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 64 total )  |  Next  |  Last  >>

Jump to: