Compile Data Set for Download or QSAR

Found 375 hits with Last Name = 'mortillo' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50184807 ((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C Show InChI InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR2				J Med Chem 49: 2143-6 (2006) Article DOI: 10.1021/jm051106d BindingDB Entry DOI: 10.7270/Q2WW7H7N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50184807 ((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C Show InChI InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR2				J Med Chem 49: 2143-6 (2006) Article DOI: 10.1021/jm051106d BindingDB Entry DOI: 10.7270/Q2WW7H7N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Mus musculus)	BDBM50184807 ((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C Show InChI InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Flk1				J Med Chem 49: 2143-6 (2006) Article DOI: 10.1021/jm051106d BindingDB Entry DOI: 10.7270/Q2WW7H7N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50184807 ((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C Show InChI InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR1				J Med Chem 49: 2143-6 (2006) Article DOI: 10.1021/jm051106d BindingDB Entry DOI: 10.7270/Q2WW7H7N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168389 (CHEMBL195218 | [4-(2,4-Difluoro-5-methoxycarbamoyl...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(NC(=O)OCCCS(C)(=O)=O)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C22H26F2N6O6S/c1-12(2)18-17(28-22(32)36-6-5-7-37(4,33)34)10-30-19(18)20(25-11-26-30)27-16-8-13(21(31)29-35-3)14(23)9-15(16)24/h8-12H,5-7H2,1-4H3,(H,28,32)(H,29,31)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0620	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (VEGFR-2)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168394 (2,4-Difluoro-5-[5-isopropyl-6-(5-isopropyl-[1,3,4]...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)C(C)C)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C22H23F2N7O3/c1-10(2)17-13(22-29-28-21(34-22)11(3)4)8-31-18(17)19(25-9-26-31)27-16-6-12(20(32)30-33-5)14(23)7-15(16)24/h6-11H,1-5H3,(H,30,32)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168397 (2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-oxazol-2-y...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4ncc(C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H20F2N6O3/c1-10(2)17-13(21-24-7-11(3)32-21)8-29-18(17)19(25-9-26-29)27-16-5-12(20(30)28-31-4)14(22)6-15(16)23/h5-10H,1-4H3,(H,28,30)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168410 (5-[6-(5-Ethyl-[1,3,4]oxadiazol-2-yl)-5-isopropyl-p...) Show SMILES CCc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NOC)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C21H21F2N7O3/c1-5-16-27-28-21(33-16)12-8-30-18(17(12)10(2)3)19(24-9-25-30)26-15-6-11(20(31)29-32-4)13(22)7-14(15)23/h6-10H,5H2,1-4H3,(H,29,31)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168398 (2,4-Difluoro-5-[5-isopropyl-6-(5-methanesulfonylme...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CS(C)(=O)=O)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H21F2N7O5S/c1-10(2)17-12(21-28-27-16(35-21)8-36(4,32)33)7-30-18(17)19(24-9-25-30)26-15-5-11(20(31)29-34-3)13(22)6-14(15)23/h5-7,9-10H,8H2,1-4H3,(H,29,31)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168390 (2,4-Difluoro-5-[6-(5-isobutyl-[1,3,4]oxadiazol-2-y...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CC(C)C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C23H25F2N7O3/c1-11(2)6-18-29-30-23(35-18)14-9-32-20(19(14)12(3)4)21(26-10-27-32)28-17-7-13(22(33)31-34-5)15(24)8-16(17)25/h7-12H,6H2,1-5H3,(H,31,33)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161538 (4-(3-Hydroxy-4-methyl-phenylamino)-5-propyl-pyrrol...) Show SMILES CCCc1c(cn2ncnc(Nc3ccc(C)c(O)c3)c12)C(=O)OCC Show InChI InChI=1S/C19H22N4O3/c1-4-6-14-15(19(25)26-5-2)10-23-17(14)18(20-11-21-23)22-13-8-7-12(3)16(24)9-13/h7-11,24H,4-6H2,1-3H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168391 (5-[6-(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-5-isopr...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)C4CC4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C22H21F2N7O3/c1-10(2)17-13(22-29-28-21(34-22)11-4-5-11)8-31-18(17)19(25-9-26-31)27-16-6-12(20(32)30-33-3)14(23)7-15(16)24/h6-11H,4-5H2,1-3H3,(H,30,32)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161532 (5-[5-Isopropyl-6-(3-piperidin-1-yl-propoxy)-pyrrol...) Show SMILES CC(C)c1c(OCCCN2CCCCC2)cn2ncnc(Nc3ccc(C)c(O)c3)c12 Show InChI InChI=1S/C24H33N5O2/c1-17(2)22-21(31-13-7-12-28-10-5-4-6-11-28)15-29-23(22)24(25-16-26-29)27-19-9-8-18(3)20(30)14-19/h8-9,14-17,30H,4-7,10-13H2,1-3H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168397 (2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-oxazol-2-y...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4ncc(C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H20F2N6O3/c1-10(2)17-13(21-24-7-11(3)32-21)8-29-18(17)19(25-9-26-29)27-16-5-12(20(30)28-31-4)14(22)6-15(16)23/h5-10H,1-4H3,(H,28,30)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168388 (5-[6-(5-Cyclopropylmethyl-[1,3,4]oxadiazol-2-yl)-5...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CC5CC5)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C23H23F2N7O3/c1-11(2)19-14(23-30-29-18(35-23)6-12-4-5-12)9-32-20(19)21(26-10-27-32)28-17-7-13(22(33)31-34-3)15(24)8-16(17)25/h7-12H,4-6H2,1-3H3,(H,31,33)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168398 (2,4-Difluoro-5-[5-isopropyl-6-(5-methanesulfonylme...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CS(C)(=O)=O)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H21F2N7O5S/c1-10(2)17-12(21-28-27-16(35-21)8-36(4,32)33)7-30-18(17)19(24-9-25-30)26-15-5-11(20(31)29-34-3)13(22)6-14(15)23/h5-7,9-10H,8H2,1-4H3,(H,29,31)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168410 (5-[6-(5-Ethyl-[1,3,4]oxadiazol-2-yl)-5-isopropyl-p...) Show SMILES CCc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NOC)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C21H21F2N7O3/c1-5-16-27-28-21(33-16)12-8-30-18(17(12)10(2)3)19(24-9-25-30)26-15-6-11(20(31)29-32-4)13(22)7-14(15)23/h6-10H,5H2,1-4H3,(H,29,31)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161531 (CHEMBL178607 | [4-(3-Hydroxy-4-methyl-phenylamino)...) Show SMILES CC(C)c1c(NC(=O)OCCCN2CCCCC2)cn2ncnc(Nc3ccc(C)c(O)c3)c12 Show InChI InChI=1S/C25H34N6O3/c1-17(2)22-20(29-25(33)34-13-7-12-30-10-5-4-6-11-30)15-31-23(22)24(26-16-27-31)28-19-9-8-18(3)21(32)14-19/h8-9,14-17,32H,4-7,10-13H2,1-3H3,(H,29,33)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161542 (1-[4-(3-Hydroxy-4-methyl-phenylamino)-5-isopropyl-...) Show SMILES CC(C)c1c(NC(=O)NCCCN2CCCCC2)cn2ncnc(Nc3ccc(C)c(O)c3)c12 Show InChI InChI=1S/C25H35N7O2/c1-17(2)22-20(30-25(34)26-10-7-13-31-11-5-4-6-12-31)15-32-23(22)24(27-16-28-32)29-19-9-8-18(3)21(33)14-19/h8-9,14-17,33H,4-7,10-13H2,1-3H3,(H2,26,30,34)(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168391 (5-[6-(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-5-isopr...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)C4CC4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C22H21F2N7O3/c1-10(2)17-13(22-29-28-21(34-22)11-4-5-11)8-31-18(17)19(25-9-26-31)27-16-6-12(20(32)30-33-3)14(23)7-15(16)24/h6-11H,4-5H2,1-3H3,(H,30,32)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168387 (2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-[1,3,4]oxa...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C20H19F2N7O3/c1-9(2)16-12(20-27-26-10(3)32-20)7-29-17(16)18(23-8-24-29)25-15-5-11(19(30)28-31-4)13(21)6-14(15)22/h5-9H,1-4H3,(H,28,30)(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168390 (2,4-Difluoro-5-[6-(5-isobutyl-[1,3,4]oxadiazol-2-y...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CC(C)C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C23H25F2N7O3/c1-11(2)6-18-29-30-23(35-18)14-9-32-20(19(14)12(3)4)21(26-10-27-32)28-17-7-13(22(33)31-34-5)15(24)8-16(17)25/h7-12H,6H2,1-5H3,(H,31,33)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168393 (5-[6-(5-Dimethylamino-[1,3,4]oxadiazol-2-yl)-5-iso...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)N(C)C)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H22F2N8O3/c1-10(2)16-12(20-27-28-21(34-20)30(3)4)8-31-17(16)18(24-9-25-31)26-15-6-11(19(32)29-33-5)13(22)7-14(15)23/h6-10H,1-5H3,(H,29,32)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168400 (2,4-Difluoro-5-[5-isopropyl-6-(3-methyl-[1,2,4]oxa...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nc(C)no4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C20H19F2N7O3/c1-9(2)16-12(20-25-10(3)27-32-20)7-29-17(16)18(23-8-24-29)26-15-5-11(19(30)28-31-4)13(21)6-14(15)22/h5-9H,1-4H3,(H,28,30)(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161539 (CHEMBL178174 | [4-(3-Hydroxy-4-methyl-phenylamino)...) Show SMILES CC(C)c1c(NC(=O)OCCCn2nccn2)cn2ncnc(Nc3ccc(C)c(O)c3)c12 Show InChI InChI=1S/C22H26N8O3/c1-14(2)19-17(28-22(32)33-10-4-9-30-24-7-8-25-30)12-29-20(19)21(23-13-26-29)27-16-6-5-15(3)18(31)11-16/h5-8,11-14,31H,4,9-10H2,1-3H3,(H,28,32)(H,23,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168393 (5-[6-(5-Dimethylamino-[1,3,4]oxadiazol-2-yl)-5-iso...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)N(C)C)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H22F2N8O3/c1-10(2)16-12(20-27-28-21(34-20)30(3)4)8-31-17(16)18(24-9-25-31)26-15-6-11(19(32)29-33-5)13(22)7-14(15)23/h6-10H,1-5H3,(H,29,32)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168387 (2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-[1,3,4]oxa...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C20H19F2N7O3/c1-9(2)16-12(20-27-26-10(3)32-20)7-29-17(16)18(23-8-24-29)25-15-5-11(19(30)28-31-4)13(21)6-14(15)22/h5-9H,1-4H3,(H,28,30)(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168400 (2,4-Difluoro-5-[5-isopropyl-6-(3-methyl-[1,2,4]oxa...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nc(C)no4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C20H19F2N7O3/c1-9(2)16-12(20-25-10(3)27-32-20)7-29-17(16)18(23-8-24-29)26-15-5-11(19(30)28-31-4)13(21)6-14(15)22/h5-9H,1-4H3,(H,28,30)(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168397 (2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-oxazol-2-y...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4ncc(C)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H20F2N6O3/c1-10(2)17-13(21-24-7-11(3)32-21)8-29-18(17)19(25-9-26-29)27-16-5-12(20(30)28-31-4)14(22)6-15(16)23/h5-10H,1-4H3,(H,28,30)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50168388 (5-[6-(5-Cyclopropylmethyl-[1,3,4]oxadiazol-2-yl)-5...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CC5CC5)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C23H23F2N7O3/c1-11(2)19-14(23-30-29-18(35-23)6-12-4-5-12)9-32-20(19)21(26-10-27-32)28-17-7-13(22(33)31-34-3)15(24)8-16(17)25/h7-12H,4-6H2,1-3H3,(H,31,33)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374709 (CHEMBL271864) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(o1)N1CCC(N)CC1 Show InChI InChI=1S/C26H29F2N9O2/c1-13(2)21-17(25-34-35-26(39-25)36-7-5-14(29)6-8-36)11-37-22(21)23(30-12-31-37)33-20-9-16(18(27)10-19(20)28)24(38)32-15-3-4-15/h9-15H,3-8,29H2,1-2H3,(H,32,38)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161535 (4-(3-Hydroxy-4-methyl-phenylamino)-5-methyl-pyrrol...) Show SMILES COC(=O)c1cn2ncnc(Nc3ccc(C)c(O)c3)c2c1C Show InChI InChI=1S/C16H16N4O3/c1-9-4-5-11(6-13(9)21)19-15-14-10(2)12(16(22)23-3)7-20(14)18-8-17-15/h4-8,21H,1-3H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374697 (CHEMBL258046) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(OC2CCNCC2)o1 Show InChI InChI=1S/C26H28F2N8O3/c1-13(2)21-17(25-34-35-26(39-25)38-15-5-7-29-8-6-15)11-36-22(21)23(30-12-31-36)33-20-9-16(18(27)10-19(20)28)24(37)32-14-3-4-14/h9-15,29H,3-8H2,1-2H3,(H,32,37)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168393 (5-[6-(5-Dimethylamino-[1,3,4]oxadiazol-2-yl)-5-iso...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)N(C)C)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H22F2N8O3/c1-10(2)16-12(20-27-28-21(34-20)30(3)4)8-31-17(16)18(24-9-25-31)26-15-6-11(19(32)29-33-5)13(22)7-14(15)23/h6-10H,1-5H3,(H,29,32)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168391 (5-[6-(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-5-isopr...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)C4CC4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C22H21F2N7O3/c1-10(2)17-13(22-29-28-21(34-22)11-4-5-11)8-31-18(17)19(25-9-26-31)27-16-6-12(20(32)30-33-3)14(23)7-15(16)24/h6-11H,4-5H2,1-3H3,(H,30,32)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374717 (CHEMBL271310) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(NCCCN(C)C)o1 Show InChI InChI=1S/C26H31F2N9O2/c1-14(2)21-17(25-34-35-26(39-25)29-8-5-9-36(3)4)12-37-22(21)23(30-13-31-37)33-20-10-16(18(27)11-19(20)28)24(38)32-15-6-7-15/h10-15H,5-9H2,1-4H3,(H,29,35)(H,32,38)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50377356 (CHEMBL410686) Show SMILES CC(C)c1c(cn2ncnc(Nc3cnc4[nH]c(C)cc4c3F)c12)-c1nnc(C)o1 Show InChI InChI=1S/C20H19FN8O/c1-9(2)15-13(20-28-27-11(4)30-20)7-29-17(15)19(23-8-24-29)26-14-6-22-18-12(16(14)21)5-10(3)25-18/h5-9H,1-4H3,(H,22,25)(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem Lett 18: 2985-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.057 BindingDB Entry DOI: 10.7270/Q28053HZ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168421 (4-(2,4-Difluoro-5-methoxycarbamoyl-phenylamino)-5-...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3cc(C(=O)NOC)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C20H21F2N5O4/c1-5-31-20(29)12-8-27-17(16(12)10(2)3)18(23-9-24-27)25-15-6-11(19(28)26-30-4)13(21)7-14(15)22/h6-10H,5H2,1-4H3,(H,26,28)(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189609 (CHEMBL209555 | N-cyclopropyl-4-fluoro-3-(2-(2-(pyr...) Show SMILES Fc1ccc(cc1CCc1cnc(Nc2ccccn2)s1)C(=O)NC1CC1 Show InChI InChI=1S/C20H19FN4OS/c21-17-9-5-14(19(26)24-15-6-7-15)11-13(17)4-8-16-12-23-20(27-16)25-18-3-1-2-10-22-18/h1-3,5,9-12,15H,4,6-8H2,(H,24,26)(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50168391 (5-[6-(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-5-isopr...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)C4CC4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C22H21F2N7O3/c1-10(2)17-13(22-29-28-21(34-22)11-4-5-11)8-31-18(17)19(25-9-26-31)27-16-6-12(20(32)30-33-3)14(23)7-15(16)24/h6-11H,4-5H2,1-3H3,(H,30,32)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human fibroblast growth factor receptor 1				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374698 (CHEMBL270193) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(NCCCCN)o1 Show InChI InChI=1S/C25H29F2N9O2/c1-13(2)20-16(24-34-35-25(38-24)29-8-4-3-7-28)11-36-21(20)22(30-12-31-36)33-19-9-15(17(26)10-18(19)27)23(37)32-14-5-6-14/h9-14H,3-8,28H2,1-2H3,(H,29,35)(H,32,37)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50161540 (4-(3-Hydroxy-4-methyl-phenylamino)-5-isopropyl-pyr...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc(C)c(O)c3)c2c1C(C)C Show InChI InChI=1S/C19H22N4O3/c1-5-26-19(25)14-9-23-17(16(14)11(2)3)18(20-10-21-23)22-13-7-6-12(4)15(24)8-13/h6-11,24H,5H2,1-4H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Vascular endothelial growth factor receptor 2				Bioorg Med Chem Lett 15: 1429-33 (2005) Article DOI: 10.1016/j.bmcl.2004.12.079 BindingDB Entry DOI: 10.7270/Q2JS9PZR
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374710 (CHEMBL271512) Show SMILES CNCCCNc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C25H29F2N9O2/c1-13(2)20-16(24-34-35-25(38-24)29-8-4-7-28-3)11-36-21(20)22(30-12-31-36)33-19-9-15(17(26)10-18(19)27)23(37)32-14-5-6-14/h9-14,28H,4-8H2,1-3H3,(H,29,35)(H,32,37)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50168398 (2,4-Difluoro-5-[5-isopropyl-6-(5-methanesulfonylme...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CS(C)(=O)=O)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H21F2N7O5S/c1-10(2)17-12(21-28-27-16(35-21)8-36(4,32)33)7-30-18(17)19(24-9-25-30)26-15-5-11(20(31)29-34-3)13(22)6-14(15)23/h5-7,9-10H,8H2,1-4H3,(H,29,31)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human fibroblast growth factor receptor 1				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168398 (2,4-Difluoro-5-[5-isopropyl-6-(5-methanesulfonylme...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CS(C)(=O)=O)o4)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C21H21F2N7O5S/c1-10(2)17-12(21-28-27-16(35-21)8-36(4,32)33)7-30-18(17)19(24-9-25-30)26-15-5-11(20(31)29-34-3)13(22)6-14(15)23/h5-7,9-10H,8H2,1-4H3,(H,29,31)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189611 (CHEMBL384909 | N-benzyl-4-fluoro-3-((2-(pyridin-2-...) Show SMILES Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H20FN5OS/c24-19-10-9-17(22(30)27-13-16-6-2-1-3-7-16)12-20(19)26-14-18-15-28-23(31-18)29-21-8-4-5-11-25-21/h1-12,15,26H,13-14H2,(H,27,30)(H,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50377361 (CHEMBL409673) Show SMILES COC(=O)c1cn2ncnc(Nc3cnc4[nH]ccc4c3)c2c1C(C)C Show InChI InChI=1S/C18H18N6O2/c1-10(2)14-13(18(25)26-3)8-24-15(14)17(21-9-22-24)23-12-6-11-4-5-19-16(11)20-7-12/h4-10H,1-3H3,(H,19,20)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem Lett 18: 2985-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.057 BindingDB Entry DOI: 10.7270/Q28053HZ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168410 (5-[6-(5-Ethyl-[1,3,4]oxadiazol-2-yl)-5-isopropyl-p...) Show SMILES CCc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NOC)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C21H21F2N7O3/c1-5-16-27-28-21(33-16)12-8-30-18(17(12)10(2)3)19(24-9-25-30)26-15-6-11(20(31)29-32-4)13(22)7-14(15)23/h6-10H,5H2,1-4H3,(H,29,31)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3 (Homo sapiens (Human))	BDBM50168403 (5-[6-(5-Difluoromethyl-[1,3,4]oxadiazol-2-yl)-5-is...) Show SMILES CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(o4)C(F)F)c(C(C)C)c23)c(F)cc1F Show InChI InChI=1S/C20H17F4N7O3/c1-8(2)14-10(19-28-29-20(34-19)16(23)24)6-31-15(14)17(25-7-26-31)27-13-4-9(18(32)30-33-3)11(21)5-12(13)22/h4-8,16H,1-3H3,(H,30,32)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50184822 (CHEMBL383671 | methyl 4-(4-fluoro-2-methyl-1H-indo...) Show SMILES COC(=O)c1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C Show InChI InChI=1S/C18H15FN4O3/c1-9-6-11-13(22-9)4-5-14(15(11)19)26-17-16-10(2)12(18(24)25-3)7-23(16)21-8-20-17/h4-8,22H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR2				J Med Chem 49: 2143-6 (2006) Article DOI: 10.1021/jm051106d BindingDB Entry DOI: 10.7270/Q2WW7H7N
					More data for this Ligand-Target Pair

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