Compile Data Set for Download or QSAR

Found 34 hits with Last Name = 'bharti' and Initial = 'sk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM242374 (US10047093, 8-31 | US10392392, Example 8-31 | US10...) Show SMILES CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 |r,wU:7.10,wD:4.3,(-8.7,2.48,;-7.36,3.25,;-7.36,4.79,;-8.7,4.02,;-6.03,2.48,;-6.03,.94,;-4.7,.17,;-3.36,.94,;-3.36,2.48,;-4.7,3.25,;-2.03,.17,;-.69,.94,;-.69,2.48,;.64,3.25,;1.97,2.48,;3.44,2.96,;4.34,1.71,;3.44,.47,;3.84,-1.02,;2.75,-2.11,;3.15,-3.6,;4.63,-4,;5.82,-2.9,;5.32,-1.42,;7.31,-3.28,;8.8,-3.66,;6.93,-4.77,;7.69,-1.79,;1.97,.94,;.64,.17,)| Show InChI InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)/t15-,17-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) up to 120 mins by Michaelis-Menten plot analysis				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512177 (CHEMBL4451418) Show SMILES O=C1NC(=O)\C(S1)=C\c1ccnc(n1)N1CCC(CNCc2ccc3ccccc3n2)CC1 Show InChI InChI=1S/C24H24N6O2S/c31-22-21(33-24(32)29-22)13-18-7-10-26-23(28-18)30-11-8-16(9-12-30)14-25-15-19-6-5-17-3-1-2-4-20(17)27-19/h1-7,10,13,16,25H,8-9,11-12,14-15H2,(H,29,31,32)/b21-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged recombinant human full length Pim-1 expressed in Escherichia coli cells				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50364776 (CHEMBL1952141 | CHEMBL1952329) Show SMILES CN1CCC(CNc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 Show InChI InChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) up to 120 mins by Michaelis-Menten plot analysis				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512180 (CHEMBL4580240) Show SMILES Cc1nc2sc3c(NC(NC3=O)c3ccc(O)c(O)c3)c2c(C)c1Br Show InChI InChI=1S/C17H14BrN3O3S/c1-6-11-13-14(25-17(11)19-7(2)12(6)18)16(24)21-15(20-13)8-3-4-9(22)10(23)5-8/h3-5,15,20,22-23H,1-2H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human PIM1 by ELISA				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512176 (CHEMBL4551767) Show SMILES COc1cc(ccc1O)C1Nc2c(sc3nc(C)c(Br)c(C)c23)C(=O)N1 Show InChI InChI=1S/C18H16BrN3O3S/c1-7-12-14-15(26-18(12)20-8(2)13(7)19)17(24)22-16(21-14)9-4-5-10(23)11(6-9)25-3/h4-6,16,21,23H,1-3H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human PIM1 by ELISA				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512179 (CHEMBL4469896) Show SMILES CSc1ncc(-c2cc([nH]c(=N)c2C#N)-c2ccc3OCOc3c2)n1Cc1ccccc1 Show InChI InChI=1S/C24H19N5O2S/c1-32-24-27-12-20(29(24)13-15-5-3-2-4-6-15)17-10-19(28-23(26)18(17)11-25)16-7-8-21-22(9-16)31-14-30-21/h2-10,12H,13-14H2,1H3,(H2,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512174 (CHEMBL4471511) Show SMILES CSc1ncc(-c2cc([nH]c(=N)c2C#N)-c2ccc(Br)cc2)n1Cc1ccccc1 Show InChI InChI=1S/C23H18BrN5S/c1-30-23-27-13-21(29(23)14-15-5-3-2-4-6-15)18-11-20(28-22(26)19(18)12-25)16-7-9-17(24)10-8-16/h2-11,13H,14H2,1H3,(H2,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<150	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512175 (CHEMBL4517325) Show SMILES CSc1ncc(-c2cc([nH]c(=O)c2C#N)-c2ccc(Br)cc2)n1Cc1ccccc1 Show InChI InChI=1S/C23H17BrN4OS/c1-30-23-26-13-21(28(23)14-15-5-3-2-4-6-15)18-11-20(27-22(29)19(18)12-25)16-7-9-17(24)10-8-16/h2-11,13H,14H2,1H3,(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<150	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50512178 (CHEMBL4591510) Show SMILES CSc1ncc(-c2cc([nH]c(=O)c2C#N)-c2ccc3OCOc3c2)n1Cc1ccccc1 Show InChI InChI=1S/C24H18N4O3S/c1-32-24-26-12-20(28(24)13-15-5-3-2-4-6-15)17-10-19(27-23(29)18(17)11-25)16-7-8-21-22(9-16)31-14-30-21/h2-10,12H,13-14H2,1H3,(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	434	n/a	n/a	n/a	n/a	n/a	n/a
NRI Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				Eur J Med Chem 172: 95-108 (2019) Article DOI: 10.1016/j.ejmech.2019.03.050 BindingDB Entry DOI: 10.7270/Q2MS3X2B
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM110190 (1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...) Show SMILES Oc1ccc(C(=O)\C=C\c2ccco2)c(O)c1 Show InChI InChI=1S/C13H10O4/c14-9-3-5-11(13(16)8-9)12(15)6-4-10-2-1-7-17-10/h1-8,14,16H/b6-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas Vishwavidyalaya (A Central University) Curated by ChEMBL					Assay Description Competitive inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate				Eur J Med Chem 92: 839-65 (2015) Article DOI: 10.1016/j.ejmech.2015.01.051 BindingDB Entry DOI: 10.7270/Q2NZ899Z
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50072958 (CHEMBL3410508) Show SMILES Clc1cccc(c1)C(=O)\C=C\c1ccco1 Show InChI InChI=1S/C13H9ClO2/c14-11-4-1-3-10(9-11)13(15)7-6-12-5-2-8-16-12/h1-9H/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas Vishwavidyalaya (A Central University) Curated by ChEMBL					Assay Description Competitive inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate				Eur J Med Chem 92: 839-65 (2015) Article DOI: 10.1016/j.ejmech.2015.01.051 BindingDB Entry DOI: 10.7270/Q2NZ899Z
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Fanconi anemia group J protein (Homo sapiens (Human))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50116791 (CHEMBL137883) Show SMILES COc1ccc(C(=O)\C=C\c2ccc(F)cc2F)c(OC)c1 Show InChI InChI=1S/C17H14F2O3/c1-21-13-6-7-14(17(10-13)22-2)16(20)8-4-11-3-5-12(18)9-15(11)19/h3-10H,1-2H3/b8-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas Vishwavidyalaya (A Central University) Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin 2				Eur J Med Chem 101: 496-524 (2015) Article DOI: 10.1016/j.ejmech.2015.06.052 BindingDB Entry DOI: 10.7270/Q2GX4DB7
					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50116790 (CHEMBL279386) Show SMILES COc1ccc(C(=O)\C=C\c2ccc(cc2)C(F)(F)F)c(OC)c1 Show InChI InChI=1S/C18H15F3O3/c1-23-14-8-9-15(17(11-14)24-2)16(22)10-5-12-3-6-13(7-4-12)18(19,20)21/h3-11H,1-2H3/b10-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas Vishwavidyalaya (A Central University) Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin 2				Eur J Med Chem 101: 496-524 (2015) Article DOI: 10.1016/j.ejmech.2015.06.052 BindingDB Entry DOI: 10.7270/Q2GX4DB7
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50121025 ((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])c(-[#8])c2)c(-[#8])cc1-[#8] Show InChI InChI=1S/C20H20O5/c1-12(2)3-6-14-10-15(19(24)11-18(14)23)16(21)7-4-13-5-8-17(22)20(25)9-13/h3-5,7-11,22-25H,6H2,1-2H3/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas Vishwavidyalaya (A Central University) Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Eur J Med Chem 92: 839-65 (2015) Article DOI: 10.1016/j.ejmech.2015.01.051 BindingDB Entry DOI: 10.7270/Q2NZ899Z
					More data for this Ligand-Target Pair