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Compile Data Set for Download or QSAR

Found 615 hits with Last Name = 'han' and Initial = 'sn'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20458
PNG
(1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-...)
Show SMILES CC(C)(C)c1ccc2[C@@H](CCc2c1)NC(=O)Nc1cccc2cnccc12 |r|
Show InChI InChI=1S/C23H25N3O/c1-23(2,3)17-8-9-18-15(13-17)7-10-21(18)26-22(27)25-20-6-4-5-16-14-24-12-11-19(16)20/h4-6,8-9,11-14,21H,7,10H2,1-3H3,(H2,25,26,27)/t21-/m1/s1
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 7 -46.5n/an/a 5n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20464
PNG
((2E)-3-[2-(piperidin-1-yl)-6-(trifluoromethyl)pyri...)
Show SMILES FC(F)(F)c1ccc(\C=C\C(=O)Nc2ccc3cccnc3c2)c(n1)N1CCCCC1
Show InChI InChI=1S/C23H21F3N4O/c24-23(25,26)20-10-7-17(22(29-20)30-13-2-1-3-14-30)8-11-21(31)28-18-9-6-16-5-4-12-27-19(16)15-18/h4-12,15H,1-3,13-14H2,(H,28,31)/b11-8+
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 27 -43.2n/an/a 34n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20334
PNG
(1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...)
Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1
Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)
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 47 -41.8n/an/a 11n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20465
PNG
(1-[(1R,2S)-6-fluoro-1-{[3-(trifluoromethyl)phenyl]...)
Show SMILES Fc1ccc2[C@@H](Cc3cccc(c3)C(F)(F)F)[C@H](CCc2c1)NC(=O)Nc1cccc2cnccc12 |r|
Show InChI InChI=1S/C28H23F4N3O/c29-21-8-9-22-18(15-21)7-10-26(24(22)14-17-3-1-5-20(13-17)28(30,31)32)35-27(36)34-25-6-2-4-19-16-33-12-11-23(19)25/h1-6,8-9,11-13,15-16,24,26H,7,10,14H2,(H2,34,35,36)/t24-,26+/m1/s1
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 58 -41.3n/an/a 46n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20285
PNG
(Resiniferatoxin | [(1R,2R,6R,10S,11R,15R,17R)-13-b...)
Show SMILES [H][C@]12OC3(Cc4ccccc4)O[C@]1(C[C@@H](C)[C@]1(O3)[C@]3([H])C=C(C)C(=O)[C@@]3(O)CC(COC(=O)Cc3ccc(O)c(OC)c3)=C[C@@]21[H])C(C)=C |c:47,t:23,TLB:11:3:12.14.13:44,THB:4:3:12.14.13:44|
Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35-,36?,37-/m1/s1
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 65 -41.0n/an/a 24n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20466
PNG
(A-784168 | CHEMBL482834 | N-[4-(trifluoromethane)s...)
Show SMILES FC(F)(F)c1cccnc1N1CCC(=CC1)C(=O)Nc1ccc(cc1)S(=O)(=O)C(F)(F)F |c:14|
Show InChI InChI=1S/C19H15F6N3O3S/c20-18(21,22)15-2-1-9-26-16(15)28-10-7-12(8-11-28)17(29)27-13-3-5-14(6-4-13)32(30,31)19(23,24)25/h1-7,9H,8,10-11H2,(H,27,29)
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 71 -40.8n/an/a 74n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20467
PNG
(3-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-1-...)
Show SMILES CC(C)(C)c1ccc2[C@H](CCc2c1)NC(=O)Nc1cccc2cnccc12 |r|
Show InChI InChI=1S/C23H25N3O/c1-23(2,3)17-8-9-18-15(13-17)7-10-21(18)26-22(27)25-20-6-4-5-16-14-24-12-11-19(16)20/h4-6,8-9,11-14,21H,7,10H2,1-3H3,(H2,25,26,27)/t21-/m0/s1
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 112 -39.7n/an/a 34n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20459
PNG
(Tinyatoxin | [(1R,2R,6R,10S,11R,15R,17R)-13-benzyl...)
Show SMILES [H][C@]12OC3(Cc4ccccc4)O[C@]1(C[C@@H](C)[C@]1(O3)[C@]3([H])C=C(C)C(=O)[C@@]3(O)CC(COC(=O)Cc3ccc(O)cc3)=C[C@@]21[H])C(C)=C |c:45,t:23,TLB:11:3:12.14.13:42,THB:4:3:12.14.13:42|
Show InChI InChI=1S/C36H38O8/c1-21(2)34-17-23(4)36-28(32(34)42-35(43-34,44-36)19-25-8-6-5-7-9-25)15-26(18-33(40)29(36)14-22(3)31(33)39)20-41-30(38)16-24-10-12-27(37)13-11-24/h5-15,23,28-29,32,37,40H,1,16-20H2,2-4H3/t23-,28+,29-,32-,33-,34-,35?,36-/m1/s1
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 589 -35.6n/an/a 129n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20468
PNG
(3-(2-bromophenyl)-1-{2-[ethyl(3-methylphenyl)amino...)
Show SMILES CCN(CCNC(=O)Nc1ccccc1Br)c1cccc(C)c1
Show InChI InChI=1S/C18H22BrN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23)
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 603 -35.5n/an/a 95n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20284
PNG
(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Show SMILES Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)
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 1.29E+3 -33.6n/an/a 282n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20460
PNG
((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCc1ccc(O)c(OC)c1
Show InChI InChI=1S/C26H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h10-11,19-21,28H,3-9,12-18,22H2,1-2H3,(H,27,29)/b11-10-
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 1.59E+3 -33.1n/an/a 132n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20462
PNG
((5Z,8Z,11Z,14Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]ic...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C28H41NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(32)29-23-22-25-20-21-26(30)27(31)24-25/h6-7,9-10,12-13,15-16,20-21,24,30-31H,2-5,8,11,14,17-19,22-23H2,1H3,(H,29,32)/b7-6-,10-9-,13-12-,16-15-
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>6.31E+3>-29.7n/an/a 1.48E+3n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20461
PNG
((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)
Show SMILES COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
Show InChI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
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 2.00E+4 -26.8n/an/a 29n/an/a7.425



Abbott Laboratories



Assay Description
The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...

J Pharmacol Exp Ther 323: 285-93 (2007)


Article DOI: 10.1124/jpet.107.124305
BindingDB Entry DOI: 10.7270/Q28K77B0
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Alpha-glucosidase MAL62


(Saccharomyces cerevisiae)		BDBM50430740
PNG
(CHEMBL2333940 | Cedryl Acetate)
Show SMILES C[C@@H]1CC[C@H]2C(C)(C)[C@@H]3C[C@@]12CC[C@@]3(C)OC(C)=O |r|
Show InChI InChI=1S/C17H28O2/c1-11-6-7-13-15(3,4)14-10-17(11,13)9-8-16(14,5)19-12(2)18/h11,13-14H,6-10H2,1-5H3/t11-,13+,14+,16-,17+/m1/s1
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n/an/a 9.40E+7n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of yeast alpha-glucosidase using para-nitrophenyl alpha-D-glucopyranoside as substrate by spectrophotometric analysis

Eur J Med Chem 62: 764-70 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.036
BindingDB Entry DOI: 10.7270/Q27H1KZX
More data for this
Ligand-Target Pair
Alpha-glucosidase MAL62


(Saccharomyces cerevisiae)		BDBM50430739
PNG
(CHEMBL1974890 | Cedrol)
Show SMILES C[C@@H]1CC[C@H]2C(C)(C)[C@H]3C[C@@]12CC[C@@]3(C)O
Show InChI InChI=1S/C15H26O/c1-10-5-6-11-13(2,3)12-9-15(10,11)8-7-14(12,4)16/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m1/s1
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n/an/a 1.30E+8n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of yeast alpha-glucosidase using para-nitrophenyl alpha-D-glucopyranoside as substrate by spectrophotometric analysis

Eur J Med Chem 62: 764-70 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.036
BindingDB Entry DOI: 10.7270/Q27H1KZX
More data for this
Ligand-Target Pair
Alpha-glucosidase MAL62


(Saccharomyces cerevisiae)		BDBM18351
PNG
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
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n/an/a 4.26E+8n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of yeast alpha-glucosidase using para-nitrophenyl alpha-D-glucopyranoside as substrate by spectrophotometric analysis

Eur J Med Chem 62: 764-70 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.036
BindingDB Entry DOI: 10.7270/Q27H1KZX
More data for this
Ligand-Target Pair
Alpha-glucosidase MAL62


(Saccharomyces cerevisiae)		BDBM50430738
PNG
(2Alpha,10Beta-Dihydroxycedryl Acetate | CHEMBL2333...)
Show SMILES CC(=O)O[C@]1(C)C[C@H](O)[C@@]23C[C@H]1C(C)(C)[C@@H]2CC[C@]3(C)O |r|
Show InChI InChI=1S/C17H28O4/c1-10(18)21-15(4)9-13(19)17-8-12(15)14(2,3)11(17)6-7-16(17,5)20/h11-13,19-20H,6-9H2,1-5H3/t11-,12-,13-,15+,16-,17+/m0/s1
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n/an/a 6.90E+8n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of yeast alpha-glucosidase using para-nitrophenyl alpha-D-glucopyranoside as substrate by spectrophotometric analysis

Eur J Med Chem 62: 764-70 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.036
BindingDB Entry DOI: 10.7270/Q27H1KZX
More data for this
Ligand-Target Pair
Alpha-glucosidase MAL62


(Saccharomyces cerevisiae)		BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 7.80E+8n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of yeast alpha-glucosidase using para-nitrophenyl alpha-D-glucopyranoside as substrate by spectrophotometric analysis

Eur J Med Chem 62: 764-70 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.036
BindingDB Entry DOI: 10.7270/Q27H1KZX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292146
PNG
(US10100057, Example 1 | US11046702, Example 1 | US...)
Show SMILES Fc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H14FN3O/c20-18-9-5-4-8-17(18)14-10-21-19-22-15(12-23(19)11-14)13-24-16-6-2-1-3-7-16/h1-12H,13H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292147
PNG
(US10100057, Example 2 | US11046702, Example 2 | US...)
Show SMILES C(Oc1ccccc1)c1cn2cc(cnc2n1)-c1ccccc1
Show InChI InChI=1S/C19H15N3O/c1-3-7-15(8-4-1)16-11-20-19-21-17(13-22(19)12-16)14-23-18-9-5-2-6-10-18/h1-13H,14H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292148
PNG
(US10100057, Example 3 | US11046702, Example 3 | US...)
Show SMILES Fc1ccc(c(F)c1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H13F2N3O/c20-14-6-7-17(18(21)8-14)13-9-22-19-23-15(11-24(19)10-13)12-25-16-4-2-1-3-5-16/h1-11H,12H2
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n/an/an/an/a<100n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292149
PNG
(US10100057, Example 4 | US11046702, Example 4 | US...)
Show SMILES COc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H17N3O2/c1-24-19-10-6-5-9-18(19)15-11-21-20-22-16(13-23(20)12-15)14-25-17-7-3-2-4-8-17/h2-13H,14H2,1H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292150
PNG
(US10100057, Example 5 | US11046702, Example 5 | US...)
Show SMILES Cc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H17N3O/c1-15-7-5-6-10-19(15)16-11-21-20-22-17(13-23(20)12-16)14-24-18-8-3-2-4-9-18/h2-13H,14H2,1H3
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n/an/an/an/a<100n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292151
PNG
(US10100057, Example 6 | US11046702, Example 6 | US...)
Show SMILES Cc1cc(F)ccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H16FN3O/c1-14-9-16(21)7-8-19(14)15-10-22-20-23-17(12-24(20)11-15)13-25-18-5-3-2-4-6-18/h2-12H,13H2,1H3
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n/an/an/an/a<100n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292152
PNG
(US10100057, Example 7 | US11046702, Example 7 | US...)
Show SMILES Fc1cccc(c1F)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H13F2N3O/c20-17-8-4-7-16(18(17)21)13-9-22-19-23-14(11-24(19)10-13)12-25-15-5-2-1-3-6-15/h1-11H,12H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292153
PNG
(US10100057, Example 59 | US10100057, Example 8 | U...)
Show SMILES Fc1ccc(cc1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H14FN3O/c20-16-8-6-14(7-9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-4-2-1-3-5-18/h1-12H,13H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292154
PNG
(US10100057, Example 9 | US11046702, Example 9 | US...)
Show SMILES Nc1cccc(c1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H16N4O/c20-16-6-4-5-14(9-16)15-10-21-19-22-17(12-23(19)11-15)13-24-18-7-2-1-3-8-18/h1-12H,13,20H2
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292155
PNG
(US10100057, Example 10 | US11046702, Example 10 | ...)
Show SMILES Nc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H16N4O/c20-18-9-5-4-8-17(18)14-10-21-19-22-15(12-23(19)11-14)13-24-16-6-2-1-3-7-16/h1-12H,13,20H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292156
PNG
(US10100057, Example 11 | US11046702, Example 11 | ...)
Show SMILES Cc1ccc(N)cc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H18N4O/c1-14-7-8-16(21)9-19(14)15-10-22-20-23-17(12-24(20)11-15)13-25-18-5-3-2-4-6-18/h2-12H,13,21H2,1H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292157
PNG
(US10100057, Example 12 | US11046702, Example 12 | ...)
Show SMILES Nc1cc(ccc1F)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H15FN4O/c20-17-7-6-13(8-18(17)21)14-9-22-19-23-15(11-24(19)10-14)12-25-16-4-2-1-3-5-16/h1-11H,12,21H2
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292158
PNG
(US10100057, Example 13 | US11046702, Example 13 | ...)
Show SMILES Fc1ccc(cc1Cl)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H13ClFN3O/c20-17-8-13(6-7-18(17)21)14-9-22-19-23-15(11-24(19)10-14)12-25-16-4-2-1-3-5-16/h1-11H,12H2
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292159
PNG
(US10100057, Example 14 | US11046702, Example 14 | ...)
Show SMILES CN(C)c1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C21H20N4O/c1-24(2)20-11-7-6-10-19(20)16-12-22-21-23-17(14-25(21)13-16)15-26-18-8-4-3-5-9-18/h3-14H,15H2,1-2H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292160
PNG
(US10100057, Example 15 | US11046702, Example 15 | ...)
Show SMILES Fc1ccc(c(Cl)c1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H13ClFN3O/c20-18-8-14(21)6-7-17(18)13-9-22-19-23-15(11-24(19)10-13)12-25-16-4-2-1-3-5-16/h1-11H,12H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292161
PNG
(US10100057, Example 16 | US11046702, Example 16 | ...)
Show SMILES Oc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H15N3O2/c23-18-9-5-4-8-17(18)14-10-20-19-21-15(12-22(19)11-14)13-24-16-6-2-1-3-7-16/h1-12,23H,13H2
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292162
PNG
(US10100057, Example 17 | US11046702, Example 17 | ...)
Show SMILES Oc1cccc(c1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H15N3O2/c23-17-6-4-5-14(9-17)15-10-20-19-21-16(12-22(19)11-15)13-24-18-7-2-1-3-8-18/h1-12,23H,13H2
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292163
PNG
(US10100057, Example 18 | US11046702, Example 18 | ...)
Show SMILES Fc1ccc(-c2cnc3nc(COc4ccccc4)cn3c2)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H13F4N3O/c21-14-6-7-17(18(8-14)20(22,23)24)13-9-25-19-26-15(11-27(19)10-13)12-28-16-4-2-1-3-5-16/h1-11H,12H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292164
PNG
(US10100057, Example 19 | US11046702, Example 19 | ...)
Show SMILES Fc1ccc(cc1F)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H13F2N3O/c20-17-7-6-13(8-18(17)21)14-9-22-19-23-15(11-24(19)10-14)12-25-16-4-2-1-3-5-16/h1-11H,12H2
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292165
PNG
(US10100057, Example 20 | US11046702, Example 20 | ...)
Show SMILES COc1cc(F)ccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H16FN3O2/c1-25-19-9-15(21)7-8-18(19)14-10-22-20-23-16(12-24(20)11-14)13-26-17-5-3-2-4-6-17/h2-12H,13H2,1H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292166
PNG
(US10100057, Example 21 | US11046702, Example 21 | ...)
Show SMILES COc1cc(ccc1F)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H16FN3O2/c1-25-19-9-14(7-8-18(19)21)15-10-22-20-23-16(12-24(20)11-15)13-26-17-5-3-2-4-6-17/h2-12H,13H2,1H3
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292167
PNG
(US10100057, Example 22 | US11046702, Example 22 | ...)
Show SMILES COc1cc(Cl)ccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H16ClN3O2/c1-25-19-9-15(21)7-8-18(19)14-10-22-20-23-16(12-24(20)11-14)13-26-17-5-3-2-4-6-17/h2-12H,13H2,1H3
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292168
PNG
(US10100057, Example 23 | US11046702, Example 23 | ...)
Show SMILES COc1cc(ccc1-c1cnc2nc(COc3ccccc3)cn2c1)C#N
Show InChI InChI=1S/C21H16N4O2/c1-26-20-9-15(10-22)7-8-19(20)16-11-23-21-24-17(13-25(21)12-16)14-27-18-5-3-2-4-6-18/h2-9,11-13H,14H2,1H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292169
PNG
(US10100057, Example 24 | US11046702, Example 24 | ...)
Show SMILES Fc1ccc(c2OCOc12)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H14FN3O3/c21-17-7-6-16(18-19(17)27-12-26-18)13-8-22-20-23-14(10-24(20)9-13)11-25-15-4-2-1-3-5-15/h1-10H,11-12H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292170
PNG
(US10100057, Example 25 | US11046702, Example 25 | ...)
Show SMILES OCc1cc(F)ccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H16FN3O2/c21-16-6-7-19(14(8-16)12-25)15-9-22-20-23-17(11-24(20)10-15)13-26-18-4-2-1-3-5-18/h1-11,25H,12-13H2
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n/an/an/an/a<100n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292171
PNG
(US10100057, Example 26 | US11046702, Example 26 | ...)
Show SMILES CSc1cc(F)ccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H16FN3OS/c1-26-19-9-15(21)7-8-18(19)14-10-22-20-23-16(12-24(20)11-14)13-25-17-5-3-2-4-6-17/h2-12H,13H2,1H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292172
PNG
(US10100057, Example 27 | US11046702, Example 27 | ...)
Show SMILES Nc1cc(F)ccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H15FN4O/c20-14-6-7-17(18(21)8-14)13-9-22-19-23-15(11-24(19)10-13)12-25-16-4-2-1-3-5-16/h1-11H,12,21H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292173
PNG
(US10100057, Example 28 | US11046702, Example 28 | ...)
Show SMILES COc1cc(c(F)cc1F)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C20H15F2N3O2/c1-26-19-7-16(17(21)8-18(19)22)13-9-23-20-24-14(11-25(20)10-13)12-27-15-5-3-2-4-6-15/h2-11H,12H2,1H3
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292174
PNG
(US10100057, Example 29 | US11046702, Example 29 | ...)
Show SMILES Fc1ncccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C18H13FN4O/c19-17-16(7-4-8-20-17)13-9-21-18-22-14(11-23(18)10-13)12-24-15-5-2-1-3-6-15/h1-11H,12H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292175
PNG
(US10100057, Example 30 | US11046702, Example 30 | ...)
Show SMILES COc1ccc(cn1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H16N4O2/c1-24-18-8-7-14(9-20-18)15-10-21-19-22-16(12-23(19)11-15)13-25-17-5-3-2-4-6-17/h2-12H,13H2,1H3
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n/an/an/an/a 750n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292176
PNG
(US10100057, Example 31 | US11046702, Example 31 | ...)
Show SMILES Fc1ccc(cn1)-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C18H13FN4O/c19-17-7-6-13(8-20-17)14-9-21-18-22-15(11-23(18)10-14)12-24-16-4-2-1-3-5-16/h1-11H,12H2
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM292177
PNG
(US10100057, Example 32 | US11046702, Example 32 | ...)
Show SMILES Cc1ccncc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H16N4O/c1-14-7-8-20-10-18(14)15-9-21-19-22-16(12-23(19)11-15)13-24-17-5-3-2-4-6-17/h2-12H,13H2,1H3
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n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...

US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
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