Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003319![]() (3-(2-{5-Guanidino-2-[(2-mercapto-benzoyl)-methyl-a...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003322![]() (3-(2-{2-[(2-Acetylamino-3-mercapto-propionyl)-meth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003317![]() (CHEMBL339832 | [18-(3-Guanidino-propyl)-2,8,11,14,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003321![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003325![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003315![]() (CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003314![]() (CHEMBL129782 | [18-(3-Guanidino-propyl)-2,5,11,14,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048982![]() ((R)-2-({(R)-2-[(R)-2-((S)-2-Amino-3-mercapto-propi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048970![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048963![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048972![]() ((R)-2-({(R)-2-[(R)-2-((S)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048967![]() ((R)-2-({(R)-2-[(R)-2-((S)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048964![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048981![]() ((S)-2-({(R)-2-[(S)-2-((R)-3-Mercapto-2-methyl-prop...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50048966![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of Geranylgeranyl transferase type I | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048968![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048969![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048974![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048975![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50048963![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of Geranylgeranyl transferase type I | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013016![]() (7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284172![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284165![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048983![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50083587![]() ((S)-2-[(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50048970![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of Geranylgeranyl transferase type I | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50058200![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013018![]() (2-Diazo-1-(7-dipropylamino-5,6,7,8-tetrahydro-naph...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50048968![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of Geranylgeranyl transferase type I | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013018![]() (2-Diazo-1-(7-dipropylamino-5,6,7,8-tetrahydro-naph...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284176![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048965![]() ((S)-2-{(R)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM13373![]() ((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048973![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284169![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013017![]() (1-Diazo-3-(7-dipropylamino-5,6,7,8-tetrahydro-naph...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013017![]() (1-Diazo-3-(7-dipropylamino-5,6,7,8-tetrahydro-naph...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048962![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003319![]() (3-(2-{5-Guanidino-2-[(2-mercapto-benzoyl)-methyl-a...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048978![]() ((R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013015![]() (CHEMBL176446 | Diazo-acetic acid 7-dipropylamino-5...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50048972![]() ((R)-2-({(R)-2-[(R)-2-((S)-2-Amino-3-mercapto-propy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of Geranylgeranyl transferase type I | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa) | BDBM50115465![]() (2-(4-Allyloxy-3-trifluoromethoxy-phenyl)-4,5-dihyd...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation Curated by ChEMBL | Assay Description Inhibition of P. aeruginosa UDP-3-O-acyl-N-acetylglucosamine Deacetylase (LpxC) in vitro. | J Med Chem 45: 3112-29 (2002) BindingDB Entry DOI: 10.7270/Q2N58KP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048977![]() ((R)-2-({(R)-1-[(R)-2-((S)-2-Amino-3-mercapto-propi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284177![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284174![]() ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50013015![]() (CHEMBL176446 | Diazo-acetic acid 7-dipropylamino-5...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | n/a |
Mount Sinai School of Medicine Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH- DPAT as radioligand | J Med Chem 33: 950-5 (1990) BindingDB Entry DOI: 10.7270/Q2V98729 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50048980![]() ((S)-2-{(E)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against Farnesyltransferase | J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa) | BDBM50115478![]() (2-(4-Methoxy-3-trifluoromethoxy-phenyl)-4,5-dihydr...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation Curated by ChEMBL | Assay Description Inhibition of P. aeruginosa UDP-3-O-acyl-N-acetylglucosamine Deacetylase (LpxC) in vitro. | J Med Chem 45: 3112-29 (2002) BindingDB Entry DOI: 10.7270/Q2N58KP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa) | BDBM50115438![]() (2-[4-(3-Methyl-but-2-enyloxy)-3-trifluoromethoxy-p...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation Curated by ChEMBL | Assay Description Inhibition of P. aeruginosa UDP-3-O-acyl-N-acetylglucosamine Deacetylase (LpxC) in vitro. | J Med Chem 45: 3112-29 (2002) BindingDB Entry DOI: 10.7270/Q2N58KP8 | |||||||||||
More data for this Ligand-Target Pair |
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