Compile Data Set for Download or QSAR

Found 64 hits with Last Name = 'paquet' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554417 (CHEMBL4758157) Show SMILES CN1CCCN(CC1)c1nccc2[nH]c(nc12)-c1cc(F)cc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50030836 (CHEMBL3355639) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc2ccc(nn12)-c1cccc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C22H19N3O4S2/c1-30(26,27)17-7-5-15(6-8-17)21-14-23-22-12-11-20(24-25(21)22)16-3-2-4-19(13-16)31(28,29)18-9-10-18/h2-8,11-14,18H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assay				J Med Chem 58: 8713-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b01605 BindingDB Entry DOI: 10.7270/Q24F1SJD
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50030836 (CHEMBL3355639) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc2ccc(nn12)-c1cccc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C22H19N3O4S2/c1-30(26,27)17-7-5-15(6-8-17)21-14-23-22-12-11-20(24-25(21)22)16-3-2-4-19(13-16)31(28,29)18-9-10-18/h2-8,11-14,18H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG channel by patch clamp technique				J Med Chem 57: 8839-48 (2014) Article DOI: 10.1021/jm500887k BindingDB Entry DOI: 10.7270/Q2ZP47Q1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50030835 (CHEMBL3355638) Show SMILES CS(=O)c1ccc(cc1)-c1cnc2ccc(nn12)-c1cccc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C22H19N3O3S2/c1-29(26)17-7-5-15(6-8-17)21-14-23-22-12-11-20(24-25(21)22)16-3-2-4-19(13-16)30(27,28)18-9-10-18/h2-8,11-14,18H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG channel by patch clamp technique				J Med Chem 57: 8839-48 (2014) Article DOI: 10.1021/jm500887k BindingDB Entry DOI: 10.7270/Q2ZP47Q1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554407 (CHEMBL4746185) Show SMILES CN1CCCN(CC1)c1nccc2[nH]c(nc12)-c1ccc(F)c(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50129589 (CHEMBL3628223) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnn2ccc(nc12)-c1cccc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C22H19N3O4S2/c1-30(26,27)17-7-5-15(6-8-17)20-14-23-25-12-11-21(24-22(20)25)16-3-2-4-19(13-16)31(28,29)18-9-10-18/h2-8,11-14,18H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assay				J Med Chem 58: 8713-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b01605 BindingDB Entry DOI: 10.7270/Q24F1SJD
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50503392 (CHEMBL4545990) Show SMILES FC(F)(F)c1cccc(Nc2cc3[nH]c(Nc4ccc(cn4)N4CCOCC4)nc3cn2)c1 Show InChI InChI=1S/C22H20F3N7O/c23-22(24,25)14-2-1-3-15(10-14)28-20-11-17-18(13-27-20)30-21(29-17)31-19-5-4-16(12-26-19)32-6-8-33-9-7-32/h1-5,10-13H,6-9H2,(H,27,28)(H2,26,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 61: 9371-9385 (2018) Article DOI: 10.1021/acs.jmedchem.8b01333 BindingDB Entry DOI: 10.7270/Q2222Z1Q
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122024 (CHEMBL3617454) Show SMILES Nc1nc(NC2CCOCC2)c2sc(cc2n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H17F3N4OS/c19-18(20,21)11-3-1-10(2-4-11)14-9-13-15(27-14)16(25-17(22)24-13)23-12-5-7-26-8-6-12/h1-4,9,12H,5-8H2,(H3,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assay				J Med Chem 58: 7572-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b01156 BindingDB Entry DOI: 10.7270/Q2RV0QHG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50129559 (CHEMBL3234071) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc2ccc(nn12)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C20H17N3O4S2/c1-28(24,25)16-8-6-14(7-9-16)19-13-21-20-11-10-18(22-23(19)20)15-4-3-5-17(12-15)29(2,26)27/h3-13H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assay				J Med Chem 58: 8713-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b01605 BindingDB Entry DOI: 10.7270/Q24F1SJD
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122022 (CHEMBL3617353) Show SMILES Nc1nc(NC2CCNCC2)c2sc(cc2n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H18F3N5S/c19-18(20,21)11-3-1-10(2-4-11)14-9-13-15(27-14)16(26-17(22)25-13)24-12-5-7-23-8-6-12/h1-4,9,12,23H,5-8H2,(H3,22,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assay				J Med Chem 58: 7572-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b01156 BindingDB Entry DOI: 10.7270/Q2RV0QHG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276209 (CHEMBL4127800) Show SMILES O=S(=O)(NCc1ccccc1)c1cccc(Nc2ccc3nccc(-c4ccncc4)c3n2)c1 Show InChI InChI=1S/C26H21N5O2S/c32-34(33,29-18-19-5-2-1-3-6-19)22-8-4-7-21(17-22)30-25-10-9-24-26(31-25)23(13-16-28-24)20-11-14-27-15-12-20/h1-17,29H,18H2,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of full length human ERG expressed in HEK293 cells assessed as reduction in tail current at holding potential of -70 mV after 6 to 7 mins ...				J Med Chem 61: 5692-5703 (2018) Article DOI: 10.1021/acs.jmedchem.8b00648 BindingDB Entry DOI: 10.7270/Q2B85BMK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50129562 (CHEMBL3628220) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnn2ccc(cc12)-c1cccc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C23H20N2O4S2/c1-30(26,27)19-7-5-16(6-8-19)22-15-24-25-12-11-18(14-23(22)25)17-3-2-4-21(13-17)31(28,29)20-9-10-20/h2-8,11-15,20H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assay				J Med Chem 58: 8713-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b01605 BindingDB Entry DOI: 10.7270/Q24F1SJD
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122020 (CHEMBL3617330) Show SMILES CNc1nc(NCCN2CCNCC2)c2sc(cc2n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H23F3N6S/c1-24-19-27-15-12-16(13-2-4-14(5-3-13)20(21,22)23)30-17(15)18(28-19)26-8-11-29-9-6-25-7-10-29/h2-5,12,25H,6-11H2,1H3,(H2,24,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assay				J Med Chem 58: 7572-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b01156 BindingDB Entry DOI: 10.7270/Q2RV0QHG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50563339 (CHEMBL4756352) Show SMILES N[C@@H](C(=O)N1CC(CNc2ccc(F)cc2)C2(CN(C2)c2cc(F)cc(F)c2)C1)c1ccc(O)cc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG incubated for 4 hrs by fluorescene microplate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00034 BindingDB Entry DOI: 10.7270/Q21N84VC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496040 (CHEMBL3120287) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C22H30N6OS/c1-23-22-25-18-15-19(30-20(18)21(26-22)24-9-4-10-27(2)3)16-5-7-17(8-6-16)28-11-13-29-14-12-28/h5-8,15H,4,9-14H2,1-3H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assay				J Med Chem 57: 1014-22 (2014) Article DOI: 10.1021/jm401760c BindingDB Entry DOI: 10.7270/Q2NG4TMV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496036 (CHEMBL3120293) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccc2nonc2c1 Show InChI InChI=1S/C18H21N7OS/c1-19-18-21-14-10-15(11-5-6-12-13(9-11)24-26-23-12)27-16(14)17(22-18)20-7-4-8-25(2)3/h5-6,9-10H,4,7-8H2,1-3H3,(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assay				J Med Chem 57: 1014-22 (2014) Article DOI: 10.1021/jm401760c BindingDB Entry DOI: 10.7270/Q2NG4TMV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50558661 (CHEMBL4763231) Show SMILES CC(C)(C)N1CCN(CC1)C(=O)c1ccc(cc1)-c1cnc(N)c(n1)-c1ccc(cc1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by IonWorks patch clamp electrophysiology method				Citation and Details BindingDB Entry DOI: 10.7270/Q2M61PZG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50563340 (CHEMBL4743418) Show SMILES Oc1ccc(CN2CC(CNc3ccccc3)C3(CN(C3)c3ccccc3)C2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG incubated for 4 hrs by fluorescene microplate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00034 BindingDB Entry DOI: 10.7270/Q21N84VC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122023 (CHEMBL3617452) Show SMILES Nc1nc(NC2CCNC2)c2sc(cc2n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H16F3N5S/c18-17(19,20)10-3-1-9(2-4-10)13-7-12-14(26-13)15(25-16(21)24-12)23-11-5-6-22-8-11/h1-4,7,11,22H,5-6,8H2,(H3,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assay				J Med Chem 58: 7572-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b01156 BindingDB Entry DOI: 10.7270/Q2RV0QHG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122019 (CHEMBL3120274) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H22F3N5S/c1-23-18-25-14-11-15(12-5-7-13(8-6-12)19(20,21)22)28-16(14)17(26-18)24-9-4-10-27(2)3/h5-8,11H,4,9-10H2,1-3H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assay				J Med Chem 58: 7572-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b01156 BindingDB Entry DOI: 10.7270/Q2RV0QHG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122019 (CHEMBL3120274) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H22F3N5S/c1-23-18-25-14-11-15(12-5-7-13(8-6-12)19(20,21)22)28-16(14)17(26-18)24-9-4-10-27(2)3/h5-8,11H,4,9-10H2,1-3H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assay				J Med Chem 57: 1014-22 (2014) Article DOI: 10.1021/jm401760c BindingDB Entry DOI: 10.7270/Q2NG4TMV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496037 (CHEMBL3120280) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C19H22F3N5OS/c1-23-18-25-14-11-15(12-5-7-13(8-6-12)28-19(20,21)22)29-16(14)17(26-18)24-9-4-10-27(2)3/h5-8,11H,4,9-10H2,1-3H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assay				J Med Chem 57: 1014-22 (2014) Article DOI: 10.1021/jm401760c BindingDB Entry DOI: 10.7270/Q2NG4TMV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554415 (CHEMBL4757759) Show SMILES CN1CCN(CC1)C(=O)C1CCN(CC1)c1nccc2[nH]c(cc12)-c1ccc(F)c(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554412 (CHEMBL4743530) Show SMILES Fc1ccc(cc1F)-c1nc2c(nccc2[nH]1)N1CCNCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496197 (CHEMBL3124981) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H14F3N3O2S/c1-27(25,26)14-8-4-11(5-9-14)15-10-23-17(22)16(24-15)12-2-6-13(7-3-12)18(19,20)21/h2-10H,1H3,(H2,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 56: 8860-71 (2013) Article DOI: 10.1021/jm401278d BindingDB Entry DOI: 10.7270/Q2GT5R5G
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496198 (CHEMBL3124985) Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)-c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C18H15F3N4O2S/c1-2-28(26,27)13-6-3-11(4-7-13)14-10-24-17(22)16(25-14)12-5-8-15(23-9-12)18(19,20)21/h3-10H,2H2,1H3,(H2,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 56: 8860-71 (2013) Article DOI: 10.1021/jm401278d BindingDB Entry DOI: 10.7270/Q2GT5R5G
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50030837 (CHEMBL3355624) Show SMILES CS(=O)c1cccc(c1)-c1ccc2ncc(-c3ccc(cc3)S(C)(=O)=O)n2n1 Show InChI InChI=1S/C20H17N3O3S2/c1-27(24)16-5-3-4-15(12-16)18-10-11-20-21-13-19(23(20)22-18)14-6-8-17(9-7-14)28(2,25)26/h3-13H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG channel by patch clamp technique				J Med Chem 57: 8839-48 (2014) Article DOI: 10.1021/jm500887k BindingDB Entry DOI: 10.7270/Q2ZP47Q1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50030832 (CHEMBL3355629) Show SMILES CS(=O)c1ccc(cc1)-c1cnc2ccc(nn12)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C20H17N3O3S2/c1-27(24)16-8-6-14(7-9-16)19-13-21-20-11-10-18(22-23(19)20)15-4-3-5-17(12-15)28(2,25)26/h3-13H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG channel by patch clamp technique				J Med Chem 57: 8839-48 (2014) Article DOI: 10.1021/jm500887k BindingDB Entry DOI: 10.7270/Q2ZP47Q1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554416 (CHEMBL4778630) Show SMILES CN1CCN(CC1)C1CCN(CC1)c1nccc2[nH]c(cc12)-c1cc(F)cc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50129560 (CHEMBL3628216) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc2ccc(cn12)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C21H18N2O4S2/c1-28(24,25)18-9-6-15(7-10-18)20-13-22-21-11-8-17(14-23(20)21)16-4-3-5-19(12-16)29(2,26)27/h3-14H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assay				J Med Chem 58: 8713-22 (2015) Article DOI: 10.1021/acs.jmedchem.5b01605 BindingDB Entry DOI: 10.7270/Q24F1SJD
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554410 (CHEMBL4789774) Show SMILES CN1CCN(CC2CCN(CC2)c2nccc3[nH]c(cc23)-c2cc(F)cc(F)c2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50558662 (CHEMBL4763365) Show SMILES CN1CCCN(CC1)C(=O)c1ccc(cc1)-c1cnc(N)c(n1)-c1ccc(cc1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by IonWorks patch clamp electrophysiology method				Citation and Details BindingDB Entry DOI: 10.7270/Q2M61PZG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50503394 (CHEMBL4447741) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccnc(Nc2nc3cnc(Nc4ccc(F)c(c4)C(F)(F)F)cc3[nH]2)c1 |r| Show InChI InChI=1S/C25H23F4N7O2/c1-13-11-36(12-14(2)38-13)23(37)15-5-6-30-21(7-15)35-24-33-19-9-22(31-10-20(19)34-24)32-16-3-4-18(26)17(8-16)25(27,28)29/h3-10,13-14H,11-12H2,1-2H3,(H,31,32)(H2,30,33,34,35)/t13-,14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 61: 9371-9385 (2018) Article DOI: 10.1021/acs.jmedchem.8b01333 BindingDB Entry DOI: 10.7270/Q2222Z1Q
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50122025 (CHEMBL3617456) Show SMILES NC1CCN(CC1)c1nc(N)nc2cc(sc12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H18F3N5S/c19-18(20,21)11-3-1-10(2-4-11)14-9-13-15(27-14)16(25-17(23)24-13)26-7-5-12(22)6-8-26/h1-4,9,12H,5-8,22H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assay				J Med Chem 58: 7572-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b01156 BindingDB Entry DOI: 10.7270/Q2RV0QHG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496039 (CHEMBL3120281) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccc(OC)nc1 Show InChI InChI=1S/C18H24N6OS/c1-19-18-22-13-10-14(12-6-7-15(25-4)21-11-12)26-16(13)17(23-18)20-8-5-9-24(2)3/h6-7,10-11H,5,8-9H2,1-4H3,(H2,19,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assay				J Med Chem 57: 1014-22 (2014) Article DOI: 10.1021/jm401760c BindingDB Entry DOI: 10.7270/Q2NG4TMV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496202 (CHEMBL3124980) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)-c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C17H13F3N4O2S/c1-27(25,26)12-5-2-10(3-6-12)13-9-23-16(21)15(24-13)11-4-7-14(22-8-11)17(18,19)20/h2-9H,1H3,(H2,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 56: 8860-71 (2013) Article DOI: 10.1021/jm401278d BindingDB Entry DOI: 10.7270/Q2GT5R5G
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496038 (CHEMBL3120265) Show SMILES CNc1nc(NCCCN(C)C)c2sc(cc2n1)-c1ccccc1 Show InChI InChI=1S/C18H23N5S/c1-19-18-21-14-12-15(13-8-5-4-6-9-13)24-16(14)17(22-18)20-10-7-11-23(2)3/h4-6,8-9,12H,7,10-11H2,1-3H3,(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assay				J Med Chem 57: 1014-22 (2014) Article DOI: 10.1021/jm401760c BindingDB Entry DOI: 10.7270/Q2NG4TMV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276210 (CHEMBL4127879) Show SMILES NS(=O)(=O)c1cccc(c1)-c1ccc2nccc(-c3ccncc3F)c2n1 Show InChI InChI=1S/C19H13FN4O2S/c20-16-11-22-8-6-14(16)15-7-9-23-18-5-4-17(24-19(15)18)12-2-1-3-13(10-12)27(21,25)26/h1-11H,(H2,21,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of full length human ERG expressed in HEK293 cells assessed as reduction in tail current at holding potential of -70 mV after 6 to 7 mins ...				J Med Chem 61: 5692-5703 (2018) Article DOI: 10.1021/acs.jmedchem.8b00648 BindingDB Entry DOI: 10.7270/Q2B85BMK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276212 (CHEMBL4129258) Show SMILES NS(=O)(=O)c1cccc(c1)-c1ccc2nccc(-c3ccnc(c3)C(F)(F)F)c2n1 Show InChI InChI=1S/C20H13F3N4O2S/c21-20(22,23)18-11-12(6-8-26-18)15-7-9-25-17-5-4-16(27-19(15)17)13-2-1-3-14(10-13)30(24,28)29/h1-11H,(H2,24,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of full length human ERG expressed in HEK293 cells assessed as reduction in tail current at holding potential of -70 mV after 6 to 7 mins ...				J Med Chem 61: 5692-5703 (2018) Article DOI: 10.1021/acs.jmedchem.8b00648 BindingDB Entry DOI: 10.7270/Q2B85BMK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276211 (CHEMBL4128198) Show SMILES OCCNS(=O)(=O)c1cccc(Nc2ccc3nccc(-c4ccncc4)c3n2)c1 Show InChI InChI=1S/C21H19N5O3S/c27-13-12-24-30(28,29)17-3-1-2-16(14-17)25-20-5-4-19-21(26-20)18(8-11-23-19)15-6-9-22-10-7-15/h1-11,14,24,27H,12-13H2,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of full length human ERG expressed in HEK293 cells assessed as reduction in tail current at holding potential of -70 mV after 6 to 7 mins ...				J Med Chem 61: 5692-5703 (2018) Article DOI: 10.1021/acs.jmedchem.8b00648 BindingDB Entry DOI: 10.7270/Q2B85BMK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50558663 (CHEMBL4798032) Show SMILES Nc1ncc(nc1-c1ccc(cc1)C(F)(F)F)-c1ccc(cc1)C(=O)N1CCNCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by IonWorks patch clamp electrophysiology method				Citation and Details BindingDB Entry DOI: 10.7270/Q2M61PZG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50558659 (CHEMBL4530341) Show SMILES NC1CCN(C1)C(=O)c1ccc(cc1)-c1cnc(N)c(n1)-c1ccc(cc1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by IonWorks patch clamp electrophysiology method				Citation and Details BindingDB Entry DOI: 10.7270/Q2M61PZG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50030833 (CHEMBL3355633) Show SMILES C[S+]([O-])c1ccc(cc1)-c1cnc2ccc(nn12)-c1cccc(c1)[S+](C)[O-] Show InChI InChI=1S/C20H17N3O2S2/c1-26(24)16-8-6-14(7-9-16)19-13-21-20-11-10-18(22-23(19)20)15-4-3-5-17(12-15)27(2)25/h3-13H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG channel by patch clamp technique				J Med Chem 57: 8839-48 (2014) Article DOI: 10.1021/jm500887k BindingDB Entry DOI: 10.7270/Q2ZP47Q1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554413 (CHEMBL4776200) Show SMILES CN1CCN(CC1)C(=O)C1CCN(CC1)c1nccc2[nH]c(nc12)-c1ccc(F)c(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50503393 (CHEMBL4575250) Show SMILES C[C@H]1CN(C[C@@H](C)N1)C(=O)c1ccnc(Nc2nc3cnc(Nc4ccc(F)c(c4)C(F)(F)F)cc3[nH]2)c1 |r| Show InChI InChI=1S/C25H24F4N8O/c1-13-11-37(12-14(2)32-13)23(38)15-5-6-30-21(7-15)36-24-34-19-9-22(31-10-20(19)35-24)33-16-3-4-18(26)17(8-16)25(27,28)29/h3-10,13-14,32H,11-12H2,1-2H3,(H,31,33)(H2,30,34,35,36)/t13-,14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 61: 9371-9385 (2018) Article DOI: 10.1021/acs.jmedchem.8b01333 BindingDB Entry DOI: 10.7270/Q2222Z1Q
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50496203 (CHEMBL3124982) Show SMILES Nc1ncc(nc1-c1ccc(nc1)C(F)(F)F)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H18F3N5O2/c22-21(23,24)17-6-5-15(11-26-17)18-19(25)27-12-16(28-18)13-1-3-14(4-2-13)20(30)29-7-9-31-10-8-29/h1-6,11-12H,7-10H2,(H2,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 56: 8860-71 (2013) Article DOI: 10.1021/jm401278d BindingDB Entry DOI: 10.7270/Q2GT5R5G
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554414 (CHEMBL4782651) Show SMILES CN1CCN(CC1)C1CCN(CC1)c1nccc2[nH]c(nc12)-c1cc(F)cc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554408 (CHEMBL4793720) Show SMILES CN1CCN(CC2CCN(CC2)c2nccc3[nH]c(nc23)-c2cc(F)cc(F)c2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50503391 (CHEMBL4471705) Show SMILES FC(F)(F)c1cccc(Nc2cc3[nH]c(Nc4ccc(cn4)N4CCNCC4)nc3cn2)c1 Show InChI InChI=1S/C22H21F3N8/c23-22(24,25)14-2-1-3-15(10-14)29-20-11-17-18(13-28-20)31-21(30-17)32-19-5-4-16(12-27-19)33-8-6-26-7-9-33/h1-5,10-13,26H,6-9H2,(H,28,29)(H2,27,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 61: 9371-9385 (2018) Article DOI: 10.1021/acs.jmedchem.8b01333 BindingDB Entry DOI: 10.7270/Q2222Z1Q
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50554411 (CHEMBL4760907) Show SMILES CN1CCN(CC2CCN(CC2)c2nc(C)cc3[nH]c(nc23)-c2cc(F)cc(F)c2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01411 BindingDB Entry DOI: 10.7270/Q2TB1BKN
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 64 total )  |  Next  |  Last  >>

Jump to: