Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542127 (CHEMBL4635482) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542123 (CHEMBL4636488) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542116 (CHEMBL4646995) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542119 (CHEMBL4644939) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542128 (CHEMBL4636337) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542132 (CHEMBL4632523) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397406 (US9987278, Compound Reference 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397407 (US9987278, Compound Reference 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397408 (US9987278, Compound Reference 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397409 (US9987278, Compound Reference 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397410 (US9987278, Compound Reference 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397411 (US9987278, Compound Reference 21) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397413 (US9987278, Compound Reference 23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397414 (US9987278, Compound Reference 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397416 (US9987278, Compound Reference 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397417 (US9987278, Compound Reference 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397419 (US9987278, Compound Reference 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397420 (US9987278, Compound Reference 30) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397422 (US9987278, Compound Reference 32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397425 (US9987278, Compound Reference 35) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397428 (US9987278, Compound Reference 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397429 (US9987278, Compound Reference 39) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397430 (US9987278, Compound Reference 40) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397431 (US9987278, Compound Reference 41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397426 (US9987278, Compound Reference 36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397404 (US9987278, Compound Reference 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397400 (US9987278, Compound Reference 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397399 (US9987278, Compound Reference 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397397 (US9987278, Compound Reference 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397427 (US9987278, Compound Reference 37) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397280 (US9987278, Compound Reference 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397395 (US9987278, Compound Reference 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397424 (US9987278, Compound Reference 34) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397418 (US9987278, Compound Reference 28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397415 (US9987278, Compound Reference 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397412 (US9987278, Compound Reference 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542133 (CHEMBL4643553) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542129 (CHEMBL4637452) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542126 (CHEMBL4642166) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542134 (CHEMBL4647780) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM50542125 (CHEMBL4643470) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method | J Med Chem 63: 7143-7162 (2020) Article DOI: 10.1021/acs.jmedchem.0c00449 BindingDB Entry DOI: 10.7270/Q24T6NWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397232 (US9987278, Compound Reference 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397393 (US9987278, Compound Reference 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397394 (US9987278, Compound Reference 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397396 (US9987278, Compound Reference 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397398 (US9987278, Compound Reference 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397401 (US9987278, Compound Reference 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397402 (US9987278, Compound Reference 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397403 (US9987278, Compound Reference 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM397405 (US9987278, Compound Reference 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2J38VZJ | |||||||||||
More data for this Ligand-Target Pair |
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