Compile Data Set for Download or QSAR

Found 1238 hits with Last Name = 'shina' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101856 ((E)-7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2C\C=C\CCCC(O)=O)c1 Show InChI InChI=1S/C24H33ClO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h2,4,6-8,11-13,19-23,26-27H,3,5,9-10,14-16H2,1H3,(H,28,29)/b4-2+,12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101861 (4-{(S)-2-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-15-16(18(22)13-17(15)21)10-12-25-11-5-7-19(23)24/h8-9,14-17,20-21H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101858 (4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)c1 Show InChI InChI=1S/C23H32O6S/c1-29-15-17-5-2-4-16(12-17)13-18(24)7-8-19-20(22(26)14-21(19)25)9-11-30-10-3-6-23(27)28/h2,4-5,7-8,12,18-21,24-25H,3,6,9-11,13-15H2,1H3,(H,27,28)/b8-7+/t18-,19-,20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101836 (6-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-5-8-14(20)10-11-15-16(21)13-17(22)19(15)25-12-7-4-6-9-18(23)24/h10-11,14-16,19-21H,2-9,12-13H2,1H3,(H,23,24)/b11-10+/t14-,15-,16+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101860 (CHEMBL64188 | {(S)-4-[(R)-3-Hydroxy-2-((1R,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCSCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-16-15(17(21)12-18(16)22)8-5-6-11-25-13-19(23)24/h9-10,14-16,18,20,22H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101861 (4-{(S)-2-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-15-16(18(22)13-17(15)21)10-12-25-11-5-7-19(23)24/h8-9,14-17,20-21H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101862 (5-[(S)-(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CSCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-15-16(18(22)12-17(15)21)13-25-11-6-5-8-19(23)24/h9-10,14-17,20-21H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101860 (CHEMBL64188 | {(S)-4-[(R)-3-Hydroxy-2-((1R,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCSCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-16-15(17(21)12-18(16)22)8-5-6-11-25-13-19(23)24/h9-10,14-16,18,20,22H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101855 (7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)-3-h...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2CCCCCCC(O)=O)c1 Show InChI InChI=1S/C24H35ClO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h6-8,11-13,19-23,26-27H,2-5,9-10,14-16H2,1H3,(H,28,29)/b12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101857 ((E)-7-{(1R,2R,3R,5R)-5-Fluoro-3-hydroxy-2-[(E)-(S)...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](F)[C@@H]2C\C=C\CCCC(O)=O)c1 Show InChI InChI=1S/C24H33FO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h2,4,6-8,11-13,19-23,26-27H,3,5,9-10,14-16H2,1H3,(H,28,29)/b4-2+,12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101863 (3-{(S)-3-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCSCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-16-15(17(21)13-18(16)22)7-5-11-25-12-10-19(23)24/h8-9,14-16,18,20,22H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101836 (6-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-5-8-14(20)10-11-15-16(21)13-17(22)19(15)25-12-7-4-6-9-18(23)24/h10-11,14-16,19-21H,2-9,12-13H2,1H3,(H,23,24)/b11-10+/t14-,15-,16+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101865 ((E)-7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2C\C=C\CCCC(O)=O)ccc1O Show InChI InChI=1S/C23H31ClO5/c1-15-12-16(8-11-21(15)26)13-17(25)9-10-19-18(20(24)14-22(19)27)6-4-2-3-5-7-23(28)29/h2,4,8-12,17-20,22,25-27H,3,5-7,13-14H2,1H3,(H,28,29)/b4-2+,10-9+/t17-,18-,19-,20-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101862 (5-[(S)-(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CSCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-15-16(18(22)12-17(15)21)13-25-11-6-5-8-19(23)24/h9-10,14-17,20-21H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149937 (US8975415, 219 | US9242973, 219) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ccc(Br)cn3)cc2[C@@]2(COC(N)=N2)C11COC1 |r,c:26| Show InChI InChI=1S/C21H21BrN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10.2	n/a	44.4	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149936 (US8975415, 218 | US9242973, 218) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@@]2(COC(N)=N2)C11COC1 |r,c:26| Show InChI InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10.3	n/a	44.7	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101863 (3-{(S)-3-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCSCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-16-15(17(21)13-18(16)22)7-5-11-25-12-10-19(23)24/h8-9,14-16,18,20,22H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101856 ((E)-7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2C\C=C\CCCC(O)=O)c1 Show InChI InChI=1S/C24H33ClO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h2,4,6-8,11-13,19-23,26-27H,3,5,9-10,14-16H2,1H3,(H,28,29)/b4-2+,12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM50101863 (3-{(S)-3-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCSCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-16-15(17(21)13-18(16)22)7-5-11-25-12-10-19(23)24/h8-9,14-16,18,20,22H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,18+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101859 (4-(2-{(1R,2R,3R,5R)-5-Fluoro-3-hydroxy-2-[(E)-(S)-...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](F)[C@@H]2CCSCCCC(O)=O)c1 Show InChI InChI=1S/C23H33FO5S/c1-29-15-17-5-2-4-16(12-17)13-18(25)7-8-20-19(21(24)14-22(20)26)9-11-30-10-3-6-23(27)28/h2,4-5,7-8,12,18-22,25-26H,3,6,9-11,13-15H2,1H3,(H,27,28)/b8-7+/t18-,19-,20-,21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149939 (US8975415, 221 | US9242973, 221) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@@]2(COC(N)=N2)C11CC1 |r,c:26| Show InChI InChI=1S/C21H21ClN4O3/c1-19(2)20(7-8-20)21(11-28-18(23)26-21)14-9-13(4-6-16(14)29-19)25-17(27)15-5-3-12(22)10-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	37.8	n/a	81.8	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149749 (US8975415, 27 | US9242973, 27) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2C2(COC(N)=N2)C11COC1 |c:26| Show InChI InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	38.2	n/a	82.2	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149938 (US8975415, 220 | US9242973, 220) Show SMILES COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(COC3)[C@]3(COC(N)=N3)c2c1 |r,c:29| Show InChI InChI=1S/C21H23N5O5/c1-19(2)20(9-29-10-20)21(11-30-18(22)26-21)13-6-12(4-5-15(13)31-19)25-17(27)14-7-24-16(28-3)8-23-14/h4-8H,9-11H2,1-3H3,(H2,22,26)(H,25,27)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	42.9	n/a	76.5	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101860 (CHEMBL64188 | {(S)-4-[(R)-3-Hydroxy-2-((1R,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCSCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-16-15(17(21)12-18(16)22)8-5-6-11-25-13-19(23)24/h9-10,14-16,18,20,22H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149752 (US8975415, 30 | US9242973, 30) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ncc(Cl)cc3F)cc2C2(COC(N)=N2)C11COC1 |c:27| Show InChI InChI=1S/C21H20ClFN4O4/c1-19(2)20(8-29-9-20)21(10-30-18(24)27-21)13-6-12(3-4-15(13)31-19)26-17(28)16-14(23)5-11(22)7-25-16/h3-7H,8-10H2,1-2H3,(H2,24,27)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	51.5	n/a	97.5	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM50101861 (4-{(S)-2-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-15-16(18(22)13-17(15)21)10-12-25-11-5-7-19(23)24/h8-9,14-17,20-21H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149942 (US8975415, 224 | US9242973, 224) Show SMILES CC1(C)Oc2ccc(NC(=O)c3cnc(cn3)C(F)F)cc2[C@@]2(COC(N)=N2)C11CC1 |r,c:28| Show InChI InChI=1S/C21H21F2N5O3/c1-19(2)20(5-6-20)21(10-30-18(24)28-21)12-7-11(3-4-15(12)31-19)27-17(29)14-9-25-13(8-26-14)16(22)23/h3-4,7-9,16H,5-6,10H2,1-2H3,(H2,24,28)(H,27,29)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	52.7	n/a	91.4	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50101858 (4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)c1 Show InChI InChI=1S/C23H32O6S/c1-29-15-17-5-2-4-16(12-17)13-18(24)7-8-19-20(22(26)14-21(19)25)9-11-30-10-3-6-23(27)28/h2,4-5,7-8,12,18-21,24-25H,3,6,9-11,13-15H2,1H3,(H,27,28)/b8-7+/t18-,19-,20-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101857 ((E)-7-{(1R,2R,3R,5R)-5-Fluoro-3-hydroxy-2-[(E)-(S)...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](F)[C@@H]2C\C=C\CCCC(O)=O)c1 Show InChI InChI=1S/C24H33FO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h2,4,6-8,11-13,19-23,26-27H,3,5,9-10,14-16H2,1H3,(H,28,29)/b4-2+,12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149941 (US8975415, 223 | US9242973, 223) Show SMILES COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(CC3)[C@]3(COC(N)=N3)c2c1 |r,c:28| Show InChI InChI=1S/C21H23N5O4/c1-19(2)20(6-7-20)21(11-29-18(22)26-21)13-8-12(4-5-15(13)30-19)25-17(27)14-9-24-16(28-3)10-23-14/h4-5,8-10H,6-7,11H2,1-3H3,(H2,22,26)(H,25,27)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	61.2	n/a	99.1	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149914 (US8975415, RP195 | US9242973, 195) Show SMILES Cc1cc(Cl)cnc1C(=O)Nc1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:29| Show InChI InChI=1S/C22H23ClN4O4/c1-12-6-13(23)8-25-17(12)18(28)26-14-4-5-16-15(7-14)22(11-30-19(24)27-22)21(9-29-10-21)20(2,3)31-16/h4-8H,9-11H2,1-3H3,(H2,24,27)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	64.5	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149920 (US8975415, RP201 | US8975415, RP203 | US9242973, R...) Show SMILES CC#Cc1cncc(c1)-c1ccc2OC(Cc3ccccc3)C3(COC3)C3(COC(N)=N3)c2c1 |c:33| Show InChI InChI=1S/C28H25N3O3/c1-2-6-20-11-22(15-30-14-20)21-9-10-24-23(13-21)28(18-33-26(29)31-28)27(16-32-17-27)25(34-24)12-19-7-4-3-5-8-19/h3-5,7-11,13-15,25H,12,16-18H2,1H3,(H2,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	67.6	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149920 (US8975415, RP201 | US8975415, RP203 | US9242973, R...) Show SMILES CC#Cc1cncc(c1)-c1ccc2OC(Cc3ccccc3)C3(COC3)C3(COC(N)=N3)c2c1 |c:33| Show InChI InChI=1S/C28H25N3O3/c1-2-6-20-11-22(15-30-14-20)21-9-10-24-23(13-21)28(18-33-26(29)31-28)27(16-32-17-27)25(34-24)12-19-7-4-3-5-8-19/h3-5,7-11,13-15,25H,12,16-18H2,1H3,(H2,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	71.1	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149916 (US8975415, RP197 | US9242973, 197) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ccc(cn3)C#N)cc2C2(COC(N)=N2)C11COC1 |c:27| Show InChI InChI=1S/C22H21N5O4/c1-20(2)21(10-29-11-21)22(12-30-19(24)27-22)15-7-14(4-6-17(15)31-20)26-18(28)16-5-3-13(8-23)9-25-16/h3-7,9H,10-12H2,1-2H3,(H2,24,27)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	72	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101861 (4-{(S)-2-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-15-16(18(22)13-17(15)21)10-12-25-11-5-7-19(23)24/h8-9,14-17,20-21H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149943 (US8975415, 227 | US9242973, 227) Show SMILES COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:29| Show InChI InChI=1S/C21H23N5O5/c1-19(2)20(9-29-10-20)21(11-30-18(22)26-21)13-6-12(4-5-15(13)31-19)25-17(27)14-7-24-16(28-3)8-23-14/h4-8H,9-11H2,1-3H3,(H2,22,26)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	79.2	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149924 (US8975415, RP205 | US9242973, RP205) Show SMILES CC#Cc1cncc(c1)-c1ccc2OC(CC3CC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:30| Show InChI InChI=1S/C25H25N3O3/c1-2-3-17-8-19(12-27-11-17)18-6-7-21-20(10-18)25(15-30-23(26)28-25)24(13-29-14-24)22(31-21)9-16-4-5-16/h6-8,10-12,16,22H,4-5,9,13-15H2,1H3,(H2,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	82.5	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149909 (US8975415, RP190 | US9242973, 190) Show SMILES CC1(C)Oc2ccc(NC(=O)c3ncc(Br)cn3)cc2C2(COC(N)=N2)C11COC1 |c:26| Show InChI InChI=1S/C20H20BrN5O4/c1-18(2)19(8-28-9-19)20(10-29-17(22)26-20)13-5-12(3-4-14(13)30-18)25-16(27)15-23-6-11(21)7-24-15/h3-7H,8-10H2,1-2H3,(H2,22,26)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	83.5	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149811 (US8975415, RP92 | US9242973, RP92) Show SMILES CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#CC |c:16| Show InChI InChI=1S/C24H25N3O3/c1-3-5-16-9-18(12-26-11-16)17-7-8-20-19(10-17)24(15-29-22(25)27-24)23(13-28-14-23)21(30-20)6-4-2/h7-12,21H,4,6,13-15H2,1-2H3,(H2,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	87.9	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149829 (US8975415, RP110 | US9242973, RP110) Show SMILES CC#Cc1cncc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:27| Show InChI InChI=1S/C23H23N3O3/c1-4-5-15-8-17(11-25-10-15)16-6-7-19-18(9-16)23(14-28-20(24)26-23)22(12-27-13-22)21(2,3)29-19/h6-11H,12-14H2,1-3H3,(H2,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	90.4	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
CoMentis, Inc. US Patent					Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...				US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50101862 (5-[(S)-(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CSCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-15-16(18(22)12-17(15)21)13-25-11-6-5-8-19(23)24/h9-10,14-17,20-21H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair

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