Compile Data Set for Download or QSAR

Found 9042 hits with Last Name = 'anumula' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440849 (CHEMBL2431588) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc(cc1)C(N)=N)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H30N4O5S/c1-4-34-23-16-19(12-15-22(23)35-17(2)3)24(29-20-13-10-18(11-14-20)25(27)28)26(31)30-36(32,33)21-8-6-5-7-9-21/h5-17,24,29H,4H2,1-3H3,(H3,27,28)(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440822 (CHEMBL2431602) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C28H31N5O7S2/c1-4-39-25-15-19(8-11-24(25)40-17(2)3)26(32-20-9-10-23-18(14-20)12-13-31-27(23)29)28(34)33-42(37,38)22-7-5-6-21(16-22)41(30,35)36/h5-17,26,32H,4H2,1-3H3,(H2,29,31)(H,33,34)(H2,30,35,36)/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440843 (CHEMBL2431614) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccccc1S(=O)(=O)CC Show InChI InChI=1S/C30H33N3O7S2/c1-5-39-26-18-22(12-14-25(26)40-20(3)4)29(32-24-13-11-23-19-31-16-15-21(23)17-24)30(34)33-42(37,38)28-10-8-7-9-27(28)41(35,36)6-2/h7-20,29,32H,5-6H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440846 (CHEMBL2431603) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H30N4O6S/c1-4-37-25-16-19(5-12-24(25)38-17(2)3)26(28(34)32-39(35,36)22-9-7-21(33)8-10-22)31-20-6-11-23-18(15-20)13-14-30-27(23)29/h5-17,26,31,33H,4H2,1-3H3,(H2,29,30)(H,32,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440848 (CHEMBL2431604) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C28H31N5O5S/c1-4-37-25-16-19(5-12-24(25)38-17(2)3)26(28(34)33-39(35,36)22-9-6-20(29)7-10-22)32-21-8-11-23-18(15-21)13-14-31-27(23)30/h5-17,26,32H,4,29H2,1-3H3,(H2,30,31)(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440847 (CHEMBL2431595) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C28H30N4O5S/c1-4-36-25-17-20(10-13-24(25)37-18(2)3)26(28(33)32-38(34,35)22-8-6-5-7-9-22)31-21-11-12-23-19(16-21)14-15-30-27(23)29/h5-18,26,31H,4H2,1-3H3,(H2,29,30)(H,32,33)/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440822 (CHEMBL2431602) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C28H31N5O7S2/c1-4-39-25-15-19(8-11-24(25)40-17(2)3)26(32-20-9-10-23-18(14-20)12-13-31-27(23)29)28(34)33-42(37,38)22-7-5-6-21(16-22)41(30,35)36/h5-17,26,32H,4H2,1-3H3,(H2,29,31)(H,33,34)(H2,30,35,36)/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440845 (CHEMBL2431611) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C29H31N3O7S2/c1-5-38-25-17-21(11-13-24(25)39-19(2)3)28(31-23-12-10-22-18-30-15-14-20(22)16-23)29(33)32-41(36,37)27-9-7-6-8-26(27)40(4,34)35/h6-19,28,31H,5H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440825 (CHEMBL2431589) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H30N4O5S/c1-4-36-25-17-20(10-13-24(25)37-18(2)3)26(28(33)32-38(34,35)22-8-6-5-7-9-22)31-21-11-12-23-19(16-21)14-15-30-27(23)29/h5-18,26,31H,4H2,1-3H3,(H2,29,30)(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440842 (CHEMBL2431609) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C28H30N4O7S2/c1-4-38-26-15-20(9-11-25(26)39-18(2)3)27(31-22-10-8-21-17-30-13-12-19(21)14-22)28(33)32-41(36,37)24-7-5-6-23(16-24)40(29,34)35/h5-18,27,31H,4H2,1-3H3,(H,32,33)(H2,29,34,35)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440841 (CHEMBL2431598) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)C(N)=O Show InChI InChI=1S/C29H31N5O6S/c1-4-39-25-16-19(8-11-24(25)40-17(2)3)26(33-21-9-10-23-18(14-21)12-13-32-27(23)30)29(36)34-41(37,38)22-7-5-6-20(15-22)28(31)35/h5-17,26,33H,4H2,1-3H3,(H2,30,32)(H2,31,35)(H,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440823 (CHEMBL2431597) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(O)c1 Show InChI InChI=1S/C28H30N4O6S/c1-4-37-25-15-19(8-11-24(25)38-17(2)3)26(28(34)32-39(35,36)22-7-5-6-21(33)16-22)31-20-9-10-23-18(14-20)12-13-30-27(23)29/h5-17,26,31,33H,4H2,1-3H3,(H2,29,30)(H,32,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440840 (CHEMBL2431599) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(CO)c1 Show InChI InChI=1S/C29H32N4O6S/c1-4-38-26-16-21(8-11-25(26)39-18(2)3)27(32-22-9-10-24-20(15-22)12-13-31-28(24)30)29(35)33-40(36,37)23-7-5-6-19(14-23)17-34/h5-16,18,27,32,34H,4,17H2,1-3H3,(H2,30,31)(H,33,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440839 (CHEMBL2431608) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(N)(=O)=O Show InChI InChI=1S/C28H30N4O7S2/c1-4-38-26-15-20(9-11-25(26)39-18(2)3)27(31-22-10-8-21-17-30-13-12-19(21)14-22)28(33)32-41(36,37)24-7-5-6-23(16-24)40(29,34)35/h5-18,27,31H,4H2,1-3H3,(H,32,33)(H2,29,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440838 (CHEMBL2431606) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C28H29N3O5S/c1-4-35-26-17-21(11-13-25(26)36-19(2)3)27(28(32)31-37(33,34)24-8-6-5-7-9-24)30-23-12-10-22-18-29-15-14-20(22)16-23/h5-19,27,30H,4H2,1-3H3,(H,31,32)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440837 (CHEMBL2431600) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(N)c1 Show InChI InChI=1S/C28H31N5O5S/c1-4-37-25-15-19(8-11-24(25)38-17(2)3)26(28(34)33-39(35,36)22-7-5-6-20(29)16-22)32-21-9-10-23-18(14-21)12-13-31-27(23)30/h5-17,26,32H,4,29H2,1-3H3,(H2,30,31)(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440824 (CHEMBL2431590) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H29N3O5S/c1-4-35-26-17-21(11-13-25(26)36-19(2)3)27(28(32)31-37(33,34)24-8-6-5-7-9-24)30-23-12-10-22-18-29-15-14-20(22)16-23/h5-19,27,30H,4H2,1-3H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440836 (CHEMBL2431607) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C28H30N4O7S2/c1-4-38-24-16-20(10-12-23(24)39-18(2)3)27(31-22-11-9-21-17-30-14-13-19(21)15-22)28(33)32-41(36,37)26-8-6-5-7-25(26)40(29,34)35/h5-18,27,31H,4H2,1-3H3,(H,32,33)(H2,29,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440835 (CHEMBL2431612) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C29H31N3O7S2/c1-5-38-27-16-21(10-12-26(27)39-19(2)3)28(31-23-11-9-22-18-30-14-13-20(22)15-23)29(33)32-41(36,37)25-8-6-7-24(17-25)40(4,34)35/h6-19,28,31H,5H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440826 (CHEMBL2431605) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C29H32N4O5S/c1-5-37-26-17-21(8-13-25(26)38-18(2)3)27(29(34)33-39(35,36)23-10-6-19(4)7-11-23)32-22-9-12-24-20(16-22)14-15-31-28(24)30/h6-18,27,32H,5H2,1-4H3,(H2,30,31)(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	197	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440834 (CHEMBL2431615) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(=O)(=O)NC Show InChI InChI=1S/C29H32N4O7S2/c1-5-39-27-16-21(10-12-26(27)40-19(2)3)28(32-23-11-9-22-18-31-14-13-20(22)15-23)29(34)33-42(37,38)25-8-6-7-24(17-25)41(35,36)30-4/h6-19,28,30,32H,5H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440833 (CHEMBL2431596) Show SMILES CCOc1cc(ccc1OC(C)C)[C@H](Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C28H30N4O5S/c1-4-36-25-17-20(10-13-24(25)37-18(2)3)26(28(33)32-38(34,35)22-8-6-5-7-9-22)31-21-11-12-23-19(16-21)14-15-30-27(23)29/h5-18,26,31H,4H2,1-3H3,(H2,29,30)(H,32,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440832 (CHEMBL2431610) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C28H30N4O7S2/c1-4-38-26-16-20(6-12-25(26)39-18(2)3)27(31-22-7-5-21-17-30-14-13-19(21)15-22)28(33)32-41(36,37)24-10-8-23(9-11-24)40(29,34)35/h5-18,27,31H,4H2,1-3H3,(H,32,33)(H2,29,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440831 (CHEMBL2431591) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)ncnc2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H29N5O5S/c1-4-36-24-14-18(10-13-23(24)37-17(2)3)25(27(33)32-38(34,35)20-8-6-5-7-9-20)31-19-11-12-21-22(15-19)29-16-30-26(21)28/h5-17,25,31H,4H2,1-3H3,(H,32,33)(H2,28,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440830 (CHEMBL2431592) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2nc(N)[nH]c2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H29N5O5S/c1-4-35-23-14-17(10-13-22(23)36-16(2)3)24(25(32)31-37(33,34)19-8-6-5-7-9-19)28-18-11-12-20-21(15-18)30-26(27)29-20/h5-16,24,28H,4H2,1-3H3,(H,31,32)(H3,27,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440829 (CHEMBL2431616) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(=O)(=O)N(C)C Show InChI InChI=1S/C30H34N4O7S2/c1-6-40-28-17-22(11-13-27(28)41-20(2)3)29(32-24-12-10-23-19-31-15-14-21(23)16-24)30(35)33-42(36,37)25-8-7-9-26(18-25)43(38,39)34(4)5/h7-20,29,32H,6H2,1-5H3,(H,33,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446797 (CHEMBL3114857) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1cccc(N)c1 Show InChI InChI=1S/C29H33N5O3/c1-4-36-26-16-21(8-11-25(26)37-18(2)3)27(29(35)33-17-19-6-5-7-22(30)14-19)34-23-9-10-24-20(15-23)12-13-32-28(24)31/h5-16,18,27,34H,4,17,30H2,1-3H3,(H2,31,32)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440828 (CHEMBL2431593) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)noc2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H28N4O6S/c1-4-34-23-14-17(10-13-21(23)35-16(2)3)24(26(31)30-37(32,33)19-8-6-5-7-9-19)28-18-11-12-20-22(15-18)36-29-25(20)27/h5-16,24,28H,4H2,1-3H3,(H2,27,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50446788 (CHEMBL3114831) Show SMILES COC(=O)Nc1ccc(c(c1)[C@H]1CCCN1C(=O)[C@H](Nc1ccc2c(N)nccc2c1)c1ccc(Cl)c(OC)c1)S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C33H36ClN5O6S/c1-19(2)46(42,43)29-12-9-23(38-33(41)45-4)18-25(29)27-6-5-15-39(27)32(40)30(21-7-11-26(34)28(17-21)44-3)37-22-8-10-24-20(16-22)13-14-36-31(24)35/h7-14,16-19,27,30,37H,5-6,15H2,1-4H3,(H2,35,36)(H,38,41)/t27-,30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F11A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446794 (CHEMBL3114841) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1ccccc1S(=O)(=O)C(C)C Show InChI InChI=1S/C32H38N4O5S/c1-6-40-28-18-23(11-14-27(28)41-20(2)3)30(36-25-12-13-26-22(17-25)15-16-34-31(26)33)32(37)35-19-24-9-7-8-10-29(24)42(38,39)21(4)5/h7-18,20-21,30,36H,6,19H2,1-5H3,(H2,33,34)(H,35,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50440827 (CHEMBL2431594) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)n[nH]c2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H29N5O5S/c1-4-35-23-14-17(10-13-22(23)36-16(2)3)24(26(32)31-37(33,34)19-8-6-5-7-9-19)28-18-11-12-20-21(15-18)29-30-25(20)27/h5-16,24,28H,4H2,1-3H3,(H,31,32)(H3,27,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble tissue factor-factor 7a using H-D-Ile-Pro-Arg-pNA as substrate				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446790 (CHEMBL3114848) Show SMILES COC(=O)Nc1ccc(c(c1)[C@H]1CCCN1C(=O)[C@H](Nc1ccc2c(N)nccc2c1)c1cccc(OC(F)F)c1)S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C33H35F2N5O6S/c1-19(2)47(43,44)28-12-10-23(39-33(42)45-3)18-26(28)27-8-5-15-40(27)31(41)29(21-6-4-7-24(17-21)46-32(34)35)38-22-9-11-25-20(16-22)13-14-37-30(25)36/h4,6-7,9-14,16-19,27,29,32,38H,5,8,15H2,1-3H3,(H2,36,37)(H,39,42)/t27-,29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440826 (CHEMBL2431605) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C29H32N4O5S/c1-5-37-26-17-21(8-13-25(26)38-18(2)3)27(29(34)33-39(35,36)23-10-6-19(4)7-11-23)32-22-9-12-24-20(16-22)14-15-31-28(24)30/h6-18,27,32H,5H2,1-4H3,(H2,30,31)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446795 (CHEMBL3114840) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1ccccc1S(=O)(=O)C1CC1 Show InChI InChI=1S/C32H36N4O5S/c1-4-40-28-18-22(9-14-27(28)41-20(2)3)30(36-24-10-13-26-21(17-24)15-16-34-31(26)33)32(37)35-19-23-7-5-6-8-29(23)42(38,39)25-11-12-25/h5-10,13-18,20,25,30,36H,4,11-12,19H2,1-3H3,(H2,33,34)(H,35,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440825 (CHEMBL2431589) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H30N4O5S/c1-4-36-25-17-20(10-13-24(25)37-18(2)3)26(28(33)32-38(34,35)22-8-6-5-7-9-22)31-21-11-12-23-19(16-21)14-15-30-27(23)29/h5-18,26,31H,4H2,1-3H3,(H2,29,30)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446788 (CHEMBL3114831) Show SMILES COC(=O)Nc1ccc(c(c1)[C@H]1CCCN1C(=O)[C@H](Nc1ccc2c(N)nccc2c1)c1ccc(Cl)c(OC)c1)S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C33H36ClN5O6S/c1-19(2)46(42,43)29-12-9-23(38-33(41)45-4)18-25(29)27-6-5-15-39(27)32(40)30(21-7-11-26(34)28(17-21)44-3)37-22-8-10-24-20(16-22)13-14-36-31(24)35/h7-14,16-19,27,30,37H,5-6,15H2,1-4H3,(H2,35,36)(H,38,41)/t27-,30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50446803 (CHEMBL3114851) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C29H32N4O3/c1-4-35-26-17-22(10-13-25(26)36-19(2)3)27(29(34)32-18-20-8-6-5-7-9-20)33-23-11-12-24-21(16-23)14-15-31-28(24)30/h5-17,19,27,33H,4,18H2,1-3H3,(H2,30,31)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F11A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446798 (CHEMBL3114856) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1cccc(O)c1 Show InChI InChI=1S/C29H32N4O4/c1-4-36-26-16-21(8-11-25(26)37-18(2)3)27(29(35)32-17-19-6-5-7-23(34)14-19)33-22-9-10-24-20(15-22)12-13-31-28(24)30/h5-16,18,27,33-34H,4,17H2,1-3H3,(H2,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50446792 (CHEMBL3114843) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1cc(NC(C)=O)ccc1S(=O)(=O)CC Show InChI InChI=1S/C33H39N5O6S/c1-6-43-29-18-23(8-12-28(29)44-20(3)4)31(38-26-9-11-27-22(16-26)14-15-35-32(27)34)33(40)36-19-24-17-25(37-21(5)39)10-13-30(24)45(41,42)7-2/h8-18,20,31,38H,6-7,19H2,1-5H3,(H2,34,35)(H,36,40)(H,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F11A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446801 (CHEMBL3114853) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1cccc(NS(N)(=O)=O)c1 Show InChI InChI=1S/C29H34N6O5S/c1-4-39-26-16-21(8-11-25(26)40-18(2)3)27(34-22-9-10-24-20(15-22)12-13-32-28(24)30)29(36)33-17-19-6-5-7-23(14-19)35-41(31,37)38/h5-16,18,27,34-35H,4,17H2,1-3H3,(H2,30,32)(H,33,36)(H2,31,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446784 (CHEMBL3114835) Show SMILES CCOc1cc([C@@H](Nc2ccc3c(N)nccc3c2)C(=O)N2CCC[C@@H]2c2cc(NC(=O)OC)ccc2S(=O)(=O)C(C)C)c(F)cc1F |r| Show InChI InChI=1S/C34H37F2N5O6S/c1-5-47-29-17-24(26(35)18-27(29)36)31(39-21-8-10-23-20(15-21)12-13-38-32(23)37)33(42)41-14-6-7-28(41)25-16-22(40-34(43)46-4)9-11-30(25)48(44,45)19(2)3/h8-13,15-19,28,31,39H,5-7,14H2,1-4H3,(H2,37,38)(H,40,43)/t28-,31-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446783 (CHEMBL3114836) Show SMILES CCOc1ccc(F)c(c1)[C@@H](Nc1ccc2c(N)nccc2c1)C(=O)N1CCC[C@@H]1c1cc(NC(=O)OC)ccc1S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C34H38FN5O6S/c1-5-46-24-10-12-28(35)26(19-24)31(38-22-8-11-25-21(17-22)14-15-37-32(25)36)33(41)40-16-6-7-29(40)27-18-23(39-34(42)45-4)9-13-30(27)47(43,44)20(2)3/h8-15,17-20,29,31,38H,5-7,16H2,1-4H3,(H2,36,37)(H,39,42)/t29-,31-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446785 (CHEMBL3114834) Show SMILES COC(=O)Nc1ccc(c(c1)[C@H]1CCCN1C(=O)[C@H](Nc1ccc2c(N)nccc2c1)c1cc(OC)ccc1F)S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C33H36FN5O6S/c1-19(2)46(42,43)29-12-8-22(38-33(41)45-4)17-26(29)28-6-5-15-39(28)32(40)30(25-18-23(44-3)9-11-27(25)34)37-21-7-10-24-20(16-21)13-14-36-31(24)35/h7-14,16-19,28,30,37H,5-6,15H2,1-4H3,(H2,35,36)(H,38,41)/t28-,30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440824 (CHEMBL2431590) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2cnccc2c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C28H29N3O5S/c1-4-35-26-17-21(11-13-25(26)36-19(2)3)27(28(32)31-37(33,34)24-8-6-5-7-9-24)30-23-12-10-22-18-29-15-14-20(22)16-23/h5-19,27,30H,4H2,1-3H3,(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446786 (CHEMBL3114833) Show SMILES COC(=O)Nc1ccc(c(c1)[C@H]1CCCN1C(=O)[C@H](Nc1ccc2c(N)nccc2c1)c1cc(C)ccc1F)S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C33H36FN5O5S/c1-19(2)45(42,43)29-12-9-23(38-33(41)44-4)18-26(29)28-6-5-15-39(28)32(40)30(25-16-20(3)7-11-27(25)34)37-22-8-10-24-21(17-22)13-14-36-31(24)35/h7-14,16-19,28,30,37H,5-6,15H2,1-4H3,(H2,35,36)(H,38,41)/t28-,30-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440823 (CHEMBL2431597) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(O)c1 Show InChI InChI=1S/C28H30N4O6S/c1-4-37-25-15-19(8-11-24(25)38-17(2)3)26(28(34)32-39(35,36)22-7-5-6-21(33)16-22)31-20-9-10-23-18(14-20)12-13-30-27(23)29/h5-17,26,31,33H,4H2,1-3H3,(H2,29,30)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440822 (CHEMBL2431602) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C28H31N5O7S2/c1-4-39-25-15-19(8-11-24(25)40-17(2)3)26(32-20-9-10-23-18(14-20)12-13-31-27(23)29)28(34)33-42(37,38)22-7-5-6-21(16-22)41(30,35)36/h5-17,26,32H,4H2,1-3H3,(H2,29,31)(H,33,34)(H2,30,35,36)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440848 (CHEMBL2431604) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1ccc(N)cc1 Show InChI InChI=1S/C28H31N5O5S/c1-4-37-25-16-19(5-12-24(25)38-17(2)3)26(28(34)33-39(35,36)22-9-6-20(29)7-10-22)32-21-8-11-23-18(15-21)13-14-31-27(23)30/h5-17,26,32H,4,29H2,1-3H3,(H2,30,31)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50446803 (CHEMBL3114851) Show SMILES CCOc1cc(ccc1OC(C)C)C(Nc1ccc2c(N)nccc2c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C29H32N4O3/c1-4-35-26-17-22(10-13-25(26)36-19(2)3)27(29(34)32-18-20-8-6-5-7-9-20)33-23-11-12-24-21(16-23)14-15-31-28(24)30/h5-17,19,27,33H,4,18H2,1-3H3,(H2,30,31)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Binding affinity to F10A (unknown origin) assessed as p-nitroaniline release by spectrophotometric analysis				ACS Med Chem Lett 5: 188-92 (2014) Article DOI: 10.1021/ml400453z BindingDB Entry DOI: 10.7270/Q2T15545
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50440822 (CHEMBL2431602) Show SMILES CCOc1cc(ccc1OC(C)C)[C@@H](Nc1ccc2c(N)nccc2c1)C(=O)NS(=O)(=O)c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C28H31N5O7S2/c1-4-39-25-15-19(8-11-24(25)40-17(2)3)26(32-20-9-10-23-18(14-20)12-13-31-27(23)29)28(34)33-42(37,38)22-7-5-6-21(16-22)41(30,35)36/h5-17,26,32H,4H2,1-3H3,(H2,29,31)(H,33,34)(H2,30,35,36)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb R&D Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 23: 5244-8 (2013) Article DOI: 10.1016/j.bmcl.2013.06.027 BindingDB Entry DOI: 10.7270/Q2S46TDQ
					More data for this Ligand-Target Pair

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