Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM152481 (Z-L-Am7(betaMe)-QA (3)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM152481 (Z-L-Am7(betaMe)-QA (3)) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM152482 ((Z-L-Am7(S-)-QA)2 (4)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM152481 (Z-L-Am7(betaMe)-QA (3)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM152482 ((Z-L-Am7(S-)-QA)2 (4)) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM152482 ((Z-L-Am7(S-)-QA)2 (4)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50200895 ((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50200895 ((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM152479 (Z-L-Am7(Ac)-QA (1)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM152480 (Z-L-Am7(AcEtMe)-QA (2)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM152480 (Z-L-Am7(AcEtMe)-QA (2)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM152480 (Z-L-Am7(AcEtMe)-QA (2)) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM152479 (Z-L-Am7(Ac)-QA (1)) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM50200895 ((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM152479 (Z-L-Am7(Ac)-QA (1)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu Institute of Technology | Assay Description For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase... | Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2 | |||||||||||
More data for this Ligand-Target Pair |