Compile Data Set for Download or QSAR

Found 4 hits with Last Name = 'barthel' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50396754 (CHEMBL2172347) Show SMILES COc1cc2CN(CCc3ccc(Cl)cc3)CCc2cc1O Show InChI InChI=1S/C18H20ClNO2/c1-22-18-11-15-12-20(9-7-14(15)10-17(18)21)8-6-13-2-4-16(19)5-3-13/h2-5,10-11,21H,6-9,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...				J Med Chem 55: 7614-22 (2012) Article DOI: 10.1021/jm3006096 BindingDB Entry DOI: 10.7270/Q2W95B9V
					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50396753 (CHEMBL2172349) Show SMILES COc1cccc(CCN2CCc3cc(O)c(OC)cc3C2)c1 Show InChI InChI=1S/C19H23NO3/c1-22-17-5-3-4-14(10-17)6-8-20-9-7-15-11-18(21)19(23-2)12-16(15)13-20/h3-5,10-12,21H,6-9,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...				J Med Chem 55: 7614-22 (2012) Article DOI: 10.1021/jm3006096 BindingDB Entry DOI: 10.7270/Q2W95B9V
					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50170646 (4-(2-{4-[(E)-3-(4-Chloro-phenyl)-allyl]-piperazin-...) Show SMILES OC(=O)c1ccc(CCN2CCN(C\C=C\c3ccc(Cl)cc3)CC2)cc1 Show InChI InChI=1S/C22H25ClN2O2/c23-21-9-5-18(6-10-21)2-1-12-24-14-16-25(17-15-24)13-11-19-3-7-20(8-4-19)22(26)27/h1-10H,11-17H2,(H,26,27)/b2-1+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...				J Med Chem 55: 7614-22 (2012) Article DOI: 10.1021/jm3006096 BindingDB Entry DOI: 10.7270/Q2W95B9V
					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50396752 (CHEMBL2172350) Show SMILES COc1ccc(CCN2CCc3cc(O)c(OC)cc3C2)cc1OC Show InChI InChI=1S/C20H25NO4/c1-23-18-5-4-14(10-20(18)25-3)6-8-21-9-7-15-11-17(22)19(24-2)12-16(15)13-21/h4-5,10-12,22H,6-9,13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-Universit£t Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...				J Med Chem 55: 7614-22 (2012) Article DOI: 10.1021/jm3006096 BindingDB Entry DOI: 10.7270/Q2W95B9V
					More data for this Ligand-Target Pair