Compile Data Set for Download or QSAR

Found 47 hits with Last Name = 'blumenstein' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102975 (US8546435, 3) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)[C@@H](Cc2c[nH]c3ccccc23)NC(C)=O)cc1 |r| Show InChI InChI=1S/C38H36N8O3/c1-24(47)42-34(19-26-21-40-31-11-5-3-9-29(26)31)36-44-45-37(46(36)23-25-14-16-28(49-2)17-15-25)35(43-38(48)33-13-7-8-18-39-33)20-27-22-41-32-12-6-4-10-30(27)32/h3-18,21-22,34-35,40-41H,19-20,23H2,1-2H3,(H,42,47)(H,43,48)/t34-,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127595 (US8791118, 158) Show SMILES COc1c(CO)cccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C27H29N5O3/c1-18(8-6-11-19-9-4-3-5-10-19)29-27(34)32-24-15-14-22-26(31-24)30-23(16-28-22)21-13-7-12-20(17-33)25(21)35-2/h3-5,7,9-10,12-16,18,33H,6,8,11,17H2,1-2H3,(H2,29,30,31,32,34)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127621 (US8791118, 195) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(C[C@H](N)C(O)=O)cc1 |r| Show InChI InChI=1S/C28H30N6O3/c1-18(6-5-9-19-7-3-2-4-8-19)31-28(37)34-25-15-14-23-26(33-25)32-24(17-30-23)21-12-10-20(11-13-21)16-22(29)27(35)36/h2-4,7-8,10-15,17-18,22H,5-6,9,16,29H2,1H3,(H,35,36)(H2,31,32,33,34,37)/t18-,22+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127620 (US8791118, 194) Show SMILES COc1cc(ccc1C(O)=O)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C26H25N5O4/c1-35-22-15-18(10-11-19(22)25(32)33)21-16-28-20-12-13-23(30-24(20)29-21)31-26(34)27-14-6-5-9-17-7-3-2-4-8-17/h2-4,7-8,10-13,15-16H,5-6,9,14H2,1H3,(H,32,33)(H2,27,29,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127593 (US8791118, 156) Show SMILES COc1cc(CO)ccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C27H29N5O3/c1-18(7-6-10-19-8-4-3-5-9-19)29-27(34)32-25-14-13-22-26(31-25)30-23(16-28-22)21-12-11-20(17-33)15-24(21)35-2/h3-5,8-9,11-16,18,33H,6-7,10,17H2,1-2H3,(H2,29,30,31,32,34)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127596 (US8791118, 159) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)-c1cn[nH]c1 Show InChI InChI=1S/C21H21N7O/c29-21(22-11-5-4-8-15-6-2-1-3-7-15)28-19-10-9-17-20(27-19)26-18(14-23-17)16-12-24-25-13-16/h1-3,6-7,9-10,12-14H,4-5,8,11H2,(H,24,25)(H2,22,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127597 (US8791118, 160) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H23N5O2/c30-19-11-9-18(10-12-19)21-16-26-20-13-14-22(28-23(20)27-21)29-24(31)25-15-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-14,16,30H,4-5,8,15H2,(H2,25,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102976 (US8546435, 4) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)cc1 |r| Show InChI InChI=1S/C36H35N7O3/c1-24(44)39-32(20-25-10-4-3-5-11-25)34-41-42-35(43(34)23-26-15-17-28(46-2)18-16-26)33(40-36(45)31-14-8-9-19-37-31)21-27-22-38-30-13-7-6-12-29(27)30/h3-19,22,32-33,38H,20-21,23H2,1-2H3,(H,39,44)(H,40,45)/t32-,33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102980 (US8546435, 8) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@@H](Cc2c[nH]c3ccccc23)NC(C)=O)cc1 |r| Show InChI InChI=1S/C36H40N8O3/c1-22(45)40-31(17-24-19-38-29-11-7-5-9-27(24)29)33-42-43-34(44(33)21-23-13-15-26(47-4)16-14-23)32(41-35(46)36(2,3)37)18-25-20-39-30-12-8-6-10-28(25)30/h5-16,19-20,31-32,38-39H,17-18,21,37H2,1-4H3,(H,40,45)(H,41,46)/t31-,32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127598 (US8791118, 161) Show SMILES COc1ncccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C25H26N6O2/c1-17(8-6-11-18-9-4-3-5-10-18)28-25(32)31-22-14-13-20-23(30-22)29-21(16-27-20)19-12-7-15-26-24(19)33-2/h3-5,7,9-10,12-17H,6,8,11H2,1-2H3,(H2,28,29,30,31,32)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127600 (US8791118, 163) Show SMILES FC(F)Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C23H23F2N7O/c24-20(25)15-32-14-17(12-28-32)19-13-27-18-9-10-21(30-22(18)29-19)31-23(33)26-11-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9-10,12-14,20H,4-5,8,11,15H2,(H2,26,29,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127594 (US8791118, 157) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccncc1 |r| Show InChI InChI=1S/C24H24N6O/c1-17(6-5-9-18-7-3-2-4-8-18)27-24(31)30-22-11-10-20-23(29-22)28-21(16-26-20)19-12-14-25-15-13-19/h2-4,7-8,10-17H,5-6,9H2,1H3,(H2,27,28,29,30,31)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127601 (US8791118, 164) Show SMILES CC(CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H25N7O/c1-16(7-6-10-17-8-4-3-5-9-17)26-23(31)29-21-12-11-19-22(28-21)27-20(14-24-19)18-13-25-30(2)15-18/h3-5,8-9,11-16H,6-7,10H2,1-2H3,(H2,26,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127599 (US8791118, 162) Show SMILES OCCCn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H27N7O2/c32-14-6-13-31-17-19(15-27-31)21-16-26-20-10-11-22(29-23(20)28-21)30-24(33)25-12-5-4-9-18-7-2-1-3-8-18/h1-3,7-8,10-11,15-17,32H,4-6,9,12-14H2,(H2,25,28,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102978 (US8546435, 6) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CO)cc1 |r| Show InChI InChI=1S/C32H34N6O4/c1-21(40)34-28(16-22-8-4-3-5-9-22)31-36-37-32(38(31)19-23-12-14-25(42-2)15-13-23)29(35-30(41)20-39)17-24-18-33-27-11-7-6-10-26(24)27/h3-15,18,28-29,33,39H,16-17,19-20H2,1-2H3,(H,34,40)(H,35,41)/t28-,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127604 (US8791118, 167) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(CO)cc1 |r| Show InChI InChI=1S/C26H27N5O2/c1-18(6-5-9-19-7-3-2-4-8-19)28-26(33)31-24-15-14-22-25(30-24)29-23(16-27-22)21-12-10-20(17-32)11-13-21/h2-4,7-8,10-16,18,32H,5-6,9,17H2,1H3,(H2,28,29,30,31,33)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127624 (US8791118, 198) Show SMILES OC(=O)c1cccc(c1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C25H23N5O3/c31-24(32)19-11-6-10-18(15-19)21-16-27-20-12-13-22(29-23(20)28-21)30-25(33)26-14-5-4-9-17-7-2-1-3-8-17/h1-3,6-8,10-13,15-16H,4-5,9,14H2,(H,31,32)(H2,26,28,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127606 (US8791118, 169) Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCC(C)(C)c3ccccc3)nc2n1 Show InChI InChI=1S/C24H27N7O/c1-24(2,18-8-5-4-6-9-18)12-7-13-25-23(32)30-21-11-10-19-22(29-21)28-20(15-26-19)17-14-27-31(3)16-17/h4-6,8-11,14-16H,7,12-13H2,1-3H3,(H2,25,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127605 (US8791118, 168) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(CCN2CCOCC2)c1 |r| Show InChI InChI=1S/C28H34N8O2/c1-21(6-5-9-22-7-3-2-4-8-22)31-28(37)34-26-11-10-24-27(33-26)32-25(19-29-24)23-18-30-36(20-23)13-12-35-14-16-38-17-15-35/h2-4,7-8,10-11,18-21H,5-6,9,12-17H2,1H3,(H2,31,32,33,34,37)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127603 (US8791118, 166) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C23H28N6O2/c1-17(6-5-9-18-7-3-2-4-8-18)25-23(30)27-20-11-10-19-22(26-20)28-21(16-24-19)29-12-14-31-15-13-29/h2-4,7-8,10-11,16-17H,5-6,9,12-15H2,1H3,(H2,25,26,27,28,30)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127602 (US8791118, 165) Show SMILES OP(O)(=O)Oc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H24N5O5P/c30-24(25-15-5-4-8-17-6-2-1-3-7-17)29-22-14-13-20-23(28-22)27-21(16-26-20)18-9-11-19(12-10-18)34-35(31,32)33/h1-3,6-7,9-14,16H,4-5,8,15H2,(H2,31,32,33)(H2,25,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102981 (US8546435, 9) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@@H](Cc2c[nH]c3ccccc23)NC=O)cc1 |r| Show InChI InChI=1S/C35H38N8O3/c1-35(2,36)34(45)40-31(17-24-19-38-29-11-7-5-9-27(24)29)33-42-41-32(43(33)20-22-12-14-25(46-3)15-13-22)30(39-21-44)16-23-18-37-28-10-6-4-8-26(23)28/h4-15,18-19,21,30-31,37-38H,16-17,20,36H2,1-3H3,(H,39,44)(H,40,45)/t30-,31-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102979 (US8546435, 7) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CNCCO2)cc1 |r| Show InChI InChI=1S/C35H39N7O4/c1-23(43)38-30(18-24-8-4-3-5-9-24)33-40-41-34(42(33)22-25-12-14-27(45-2)15-13-25)31(39-35(44)32-21-36-16-17-46-32)19-26-20-37-29-11-7-6-10-28(26)29/h3-15,20,30-32,36-37H,16-19,21-22H2,1-2H3,(H,38,43)(H,39,44)/t30-,31-,32+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102977 (US8546435, 5) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2ccccc2)NC=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)cc1 |r| Show InChI InChI=1S/C35H33N7O3/c1-45-27-16-14-25(15-17-27)22-42-33(31(38-23-43)19-24-9-3-2-4-10-24)40-41-34(42)32(39-35(44)30-13-7-8-18-36-30)20-26-21-37-29-12-6-5-11-28(26)29/h2-18,21,23,31-32,37H,19-20,22H2,1H3,(H,38,43)(H,39,44)/t31-,32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127619 (US8791118, 189) Show SMILES OCCn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C23H25N7O2/c31-13-12-30-16-18(14-26-30)20-15-25-19-9-10-21(28-22(19)27-20)29-23(32)24-11-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-10,14-16,31H,4-5,8,11-13H2,(H2,24,27,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127592 (US8791118, 155) Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C22H23N7O/c1-29-15-17(13-25-29)19-14-24-18-10-11-20(27-21(18)26-19)28-22(30)23-12-6-5-9-16-7-3-2-4-8-16/h2-4,7-8,10-11,13-15H,5-6,9,12H2,1H3,(H2,23,26,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127607 (US8791118, 170) Show SMILES CCCn1cc(cn1)-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C25H29N7O/c1-3-14-32-17-20(15-27-32)22-16-26-21-12-13-23(30-24(21)29-22)31-25(33)28-18(2)8-7-11-19-9-5-4-6-10-19/h4-6,9-10,12-13,15-18H,3,7-8,11,14H2,1-2H3,(H2,28,29,30,31,33)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127608 (US8791118, 171) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C22H23N7O/c1-15(6-5-9-16-7-3-2-4-8-16)26-22(30)29-20-11-10-18-21(28-20)27-19(14-23-18)17-12-24-25-13-17/h2-4,7-8,10-15H,5-6,9H2,1H3,(H,24,25)(H2,26,27,28,29,30)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127622 (US8791118, 196) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C26H25N5O3/c1-17(7-5-10-18-8-3-2-4-9-18)28-26(34)31-23-14-13-21-24(30-23)29-22(16-27-21)19-11-6-12-20(15-19)25(32)33/h2-4,6,8-9,11-17H,5,7,10H2,1H3,(H,32,33)(H2,28,29,30,31,34)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127590 (US8791118, 108) Show SMILES CCn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C23H25N7O/c1-2-30-16-18(14-26-30)20-15-25-19-11-12-21(28-22(19)27-20)29-23(31)24-13-7-6-10-17-8-4-3-5-9-17/h3-5,8-9,11-12,14-16H,2,6-7,10,13H2,1H3,(H2,24,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127610 (US8791118, 173) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)N1CCCC1 |r| Show InChI InChI=1S/C23H28N6O/c1-17(8-7-11-18-9-3-2-4-10-18)25-23(30)27-20-13-12-19-22(26-20)28-21(16-24-19)29-14-5-6-15-29/h2-4,9-10,12-13,16-17H,5-8,11,14-15H2,1H3,(H2,25,26,27,28,30)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127609 (US8791118, 172) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)N1CCCC1 Show InChI InChI=1S/C22H26N6O/c29-22(23-13-5-4-10-17-8-2-1-3-9-17)26-19-12-11-18-21(25-19)27-20(16-24-18)28-14-6-7-15-28/h1-3,8-9,11-12,16H,4-7,10,13-15H2,(H2,23,25,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127623 (US8791118, 197) Show SMILES N[C@@H](Cc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1)C(O)=O |r| Show InChI InChI=1S/C27H28N6O3/c28-21(26(34)35)16-19-9-11-20(12-10-19)23-17-30-22-13-14-24(32-25(22)31-23)33-27(36)29-15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-14,17,21H,4-5,8,15-16,28H2,(H,34,35)(H2,29,31,32,33,36)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127591 (US8791118, 127) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)-c1cnn(CCN2CCOCC2)c1 Show InChI InChI=1S/C27H32N8O2/c36-27(28-11-5-4-8-21-6-2-1-3-7-21)33-25-10-9-23-26(32-25)31-24(19-29-23)22-18-30-35(20-22)13-12-34-14-16-37-17-15-34/h1-3,6-7,9-10,18-20H,4-5,8,11-17H2,(H2,28,31,32,33,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127615 (US8791118, 178) Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C26H27N5O3/c1-33-22-13-11-19(16-23(22)34-2)21-17-28-20-12-14-24(30-25(20)29-21)31-26(32)27-15-7-6-10-18-8-4-3-5-9-18/h3-5,8-9,11-14,16-17H,6-7,10,15H2,1-2H3,(H2,27,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127616 (US8791118, 179) Show SMILES COc1ccccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C26H27N5O2/c1-18(9-8-12-19-10-4-3-5-11-19)28-26(32)31-24-16-15-21-25(30-24)29-22(17-27-21)20-13-6-7-14-23(20)33-2/h3-7,10-11,13-18H,8-9,12H2,1-2H3,(H2,28,29,30,31,32)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127617 (US8791118, 180) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(C)c1 |r| Show InChI InChI=1S/C23H25N7O/c1-16(7-6-10-17-8-4-3-5-9-17)26-23(31)29-21-12-11-19-22(28-21)27-20(14-24-19)18-13-25-30(2)15-18/h3-5,8-9,11-16H,6-7,10H2,1-2H3,(H2,26,27,28,29,31)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127618 (US8791118, 181) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cccc(CO)c1 |r| Show InChI InChI=1S/C26H27N5O2/c1-18(7-5-10-19-8-3-2-4-9-19)28-26(33)31-24-14-13-22-25(30-24)29-23(16-27-22)21-12-6-11-20(15-21)17-32/h2-4,6,8-9,11-16,18,32H,5,7,10,17H2,1H3,(H2,28,29,30,31,33)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127612 (US8791118, 175) Show SMILES OCc1cccc(c1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C25H25N5O2/c31-17-19-10-6-11-20(15-19)22-16-27-21-12-13-23(29-24(21)28-22)30-25(32)26-14-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-13,15-16,31H,4-5,9,14,17H2,(H2,26,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127611 (US8791118, 174) Show SMILES Oc1ccc(cc1F)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H22FN5O2/c25-18-14-17(9-11-21(18)31)20-15-27-19-10-12-22(29-23(19)28-20)30-24(32)26-13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9-12,14-15,31H,4-5,8,13H2,(H2,26,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127614 (US8791118, 177) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1c(C)n[nH]c1C |r| Show InChI InChI=1S/C24H27N7O/c1-15(8-7-11-18-9-5-4-6-10-18)26-24(32)29-21-13-12-19-23(28-21)27-20(14-25-19)22-16(2)30-31-17(22)3/h4-6,9-10,12-15H,7-8,11H2,1-3H3,(H,30,31)(H2,26,27,28,29,32)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127613 (US8791118, 176) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)N1CCOCC1 Show InChI InChI=1S/C22H26N6O2/c29-22(23-11-5-4-8-17-6-2-1-3-7-17)26-19-10-9-18-21(25-19)27-20(16-24-18)28-12-14-30-15-13-28/h1-3,6-7,9-10,16H,4-5,8,11-15H2,(H2,23,25,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102983 (US8546435, 17) Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)OCC(C)C)cc1 |r| Show InChI InChI=1S/C33H37N5O3/c1-23(2)22-41-33(39)35-30(19-26-20-34-29-12-8-7-11-28(26)29)32-37-36-31(18-15-24-9-5-4-6-10-24)38(32)21-25-13-16-27(40-3)17-14-25/h4-14,16-17,20,23,30,34H,15,18-19,21-22H2,1-3H3,(H,35,39)/t30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM102982 (US8546435, 15) Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2ccc3ccccc3c2)NC(=O)OC(C)(C)C)cc1 |r| Show InChI InChI=1S/C37H39N5O3/c1-37(2,3)45-36(43)39-33(22-26-13-16-27-9-5-6-10-28(27)21-26)35-41-40-34(42(35)24-25-14-18-30(44-4)19-15-25)20-17-29-23-38-32-12-8-7-11-31(29)32/h5-16,18-19,21,23,33,38H,17,20,22,24H2,1-4H3,(H,39,43)/t33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
AEterna Zentaris GmbH; Centre National de la Recherche Scientifique; University of Montpellier I; University of Montpellier II US Patent					Assay Description Competitive binding assay using ghrelin receptor.				US Patent US8546435 (2013) BindingDB Entry DOI: 10.7270/Q22N50XS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127627 (US8791118, 203) Show SMILES COCc1cccc(c1)-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C27H29N5O2/c1-19(8-6-11-20-9-4-3-5-10-20)29-27(33)32-25-15-14-23-26(31-25)30-24(17-28-23)22-13-7-12-21(16-22)18-34-2/h3-5,7,9-10,12-17,19H,6,8,11,18H2,1-2H3,(H2,29,30,31,32,33)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127625 (US8791118, 201) Show SMILES OCCOCCOc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C28H31N5O4/c34-16-17-36-18-19-37-23-11-9-22(10-12-23)25-20-30-24-13-14-26(32-27(24)31-25)33-28(35)29-15-5-4-8-21-6-2-1-3-7-21/h1-3,6-7,9-14,20,34H,4-5,8,15-19H2,(H2,29,31,32,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127626 (US8791118, 202) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C30H34N6O3/c37-30(31-15-5-4-8-23-6-2-1-3-7-23)35-28-14-13-26-29(34-28)33-27(22-32-26)24-9-11-25(12-10-24)39-21-18-36-16-19-38-20-17-36/h1-3,6-7,9-14,22H,4-5,8,15-21H2,(H2,31,33,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair