Found 11 hits with Last Name = 'brink' and Initial = 'cb' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-2A adrenergic receptor
(PIG) | BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)Show InChI InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| Purchase
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| PDB
PubMed
| 35.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Alpha-2A adrenergic receptor
(PIG) | BDBM50262179
(Iodoclonidine-p | p-iodoclonidine)Show InChI InChI=1S/C9H8Cl2IN3/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2H2,(H2,13,14,15)/p+1 | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 51.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM81979
(CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanab...)Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl |w:5.5| Show InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
DrugBank
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 57.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM50016897
(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)Show SMILES Clc1cccc(Cl)c1\[#7]=[#6]-1\[#7]-[#6]-[#6]-[#7]-1 Show InChI InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 85.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM81926
(Aminoclonidine, p | CAS_66711-21-5 | NSC_51763 | p...)Show InChI InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 288 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| 479 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Alpha-2A adrenergic receptor
(PIG) | BDBM84342
(4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol...)Show InChI InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| 646 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM50027069
((2,6-Dimethyl-phenyl)-[1,3]thiazinan-2-ylidene-ami...)Show InChI InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM35234
(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| 5.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM85676
(BHT-933 | CAS_128-37-0 | NSC_169743)Show InChI InChI=1S/C9H15N3O/c1-2-12-5-3-7-8(4-6-12)13-9(10)11-7/h2-6H2,1H3,(H2,10,11) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(PIG) | BDBM25392
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this
Ligand-Target Pair | |
Search and Browse
