Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50042235 (2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Lille 2 Curated by ChEMBL | Assay Description In vitro binding affinity towards Angiotensin II receptor, type 1 of human hepatoma cell line PLC-PRF-5 | J Med Chem 45: 4794-8 (2002) BindingDB Entry DOI: 10.7270/Q2QC02TH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50119657 (8-Butyl-7-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Lille 2 Curated by ChEMBL | Assay Description In vitro binding affinity towards Angiotensin II receptor, type 1 of human hepatoma cell line PLC-PRF-5 | J Med Chem 45: 4794-8 (2002) BindingDB Entry DOI: 10.7270/Q2QC02TH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50089990 (2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Lille 2 Curated by ChEMBL | Assay Description In vitro binding affinity towards Angiotensin II receptor, type 1 of human hepatoma cell line PLC-PRF-5 | J Med Chem 45: 4794-8 (2002) BindingDB Entry DOI: 10.7270/Q2QC02TH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50119658 (7-Butyl-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Lille 2 Curated by ChEMBL | Assay Description In vitro binding affinity towards Angiotensin II receptor, type 1 of human hepatoma cell line PLC-PRF-5 | J Med Chem 45: 4794-8 (2002) BindingDB Entry DOI: 10.7270/Q2QC02TH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50184349 ((Z)-4-[6-((Z)-3-carboxy-3-hydroxy-acryloyl)-1-(4-f...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesium | Bioorg Med Chem Lett 19: 4806-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.044 BindingDB Entry DOI: 10.7270/Q2862K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50480767 (CHEMBL562899) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesium | Bioorg Med Chem Lett 19: 4806-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.044 BindingDB Entry DOI: 10.7270/Q2862K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483782 (CHEMBL1770431) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483781 (CHEMBL1770430) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483779 (CHEMBL1770428) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50480768 (CHEMBL559753) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesium | Bioorg Med Chem Lett 19: 4806-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.044 BindingDB Entry DOI: 10.7270/Q2862K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50184349 ((Z)-4-[6-((Z)-3-carboxy-3-hydroxy-acryloyl)-1-(4-f...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesium | Bioorg Med Chem Lett 19: 4806-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.044 BindingDB Entry DOI: 10.7270/Q2862K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50480767 (CHEMBL562899) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesium | Bioorg Med Chem Lett 19: 4806-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.044 BindingDB Entry DOI: 10.7270/Q2862K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483782 (CHEMBL1770431) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483779 (CHEMBL1770428) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483781 (CHEMBL1770430) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50480768 (CHEMBL559753) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli BL21 (DE3) by gel based assay in presence of magnesium | Bioorg Med Chem Lett 19: 4806-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.044 BindingDB Entry DOI: 10.7270/Q2862K73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483778 (CHEMBL1770427) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483780 (CHEMBL1770429) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483778 (CHEMBL1770427) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50483780 (CHEMBL1770429) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Facult£s Universitaires Notre-Dame de la Paix (FUNDP) Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity after 1 hr by gel based assay in presence of magnesium | Eur J Med Chem 46: 1749-56 (2011) Article DOI: 10.1016/j.ejmech.2011.02.028 BindingDB Entry DOI: 10.7270/Q29S1TVV | |||||||||||
More data for this Ligand-Target Pair |