Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315675 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-2-yl)py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315688 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315674 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-3-yl)py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315676 (((3R,4S)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315686 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315677 (((3R,4S)-1-cyclobutyl-4-(2,4-difluorophenyl)pyrrol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315680 (((3S,4R)-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315681 (((3S,4R)-4-(2,4-difluorophenyl)-1-isopropylpyrroli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50378743 (CHEMBL1204061) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315679 (((3R,4S)-1-cyclopropyl-4-(2,4-difluorophenyl)pyrro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315669 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-4-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50378747 (CHEMBL1204056) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315691 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50378748 (CHEMBL1204054) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315673 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50315692 (CHEMBL1090488 | CHEMBL1204059) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315673 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50029747 ((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315692 (CHEMBL1090488 | CHEMBL1204059) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50378743 (CHEMBL1204061) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315676 (((3R,4S)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315691 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315674 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-3-yl)py...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315672 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50378748 (CHEMBL1204054) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315677 (((3R,4S)-1-cyclobutyl-4-(2,4-difluorophenyl)pyrrol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315669 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-4-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315675 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-2-yl)py...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315689 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315688 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50064027 (5-{(2S,3S,4R,5R,6S)-3,4-Bis-benzyloxy-5-(1H-imidaz...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Binding affinity for human receptor subtype hSSTR4. | J Med Chem 41: 1382-91 (1998) Article DOI: 10.1021/jm9800346 BindingDB Entry DOI: 10.7270/Q28S4P2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50378746 (CHEMBL1204065) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315681 (((3S,4R)-4-(2,4-difluorophenyl)-1-isopropylpyrroli...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50378747 (CHEMBL1204056) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 172 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315687 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315678 (((3R,4S)-1-butyl-4-(2,4-difluorophenyl)pyrrolidin-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 233 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315680 (((3S,4R)-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 264 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315679 (((3R,4S)-1-cyclopropyl-4-(2,4-difluorophenyl)pyrro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315668 (((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-2-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM50485596 (LEUKOTRIEN C4 | Leukotriene C4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Deutsches Krebsforschungszentrum Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of GSSG uptake in membrane vesicle from MRP1-expressing HeLa cells | Biochem J 314: 433-7 (1996) Article DOI: 10.1042/bj3140433 BindingDB Entry DOI: 10.7270/Q2P271Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50064027 (5-{(2S,3S,4R,5R,6S)-3,4-Bis-benzyloxy-5-(1H-imidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Binding affinity for human receptor subtype hSSTR1 | J Med Chem 41: 1382-91 (1998) Article DOI: 10.1021/jm9800346 BindingDB Entry DOI: 10.7270/Q28S4P2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315683 (((3S,4R)-4-(2,4-difluorophenyl)-1-methylpyrrolidin...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 346 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315686 (((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50315682 (((3S,4R)-4-(2,4-difluorophenyl)-1-ethylpyrrolidin-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 355 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | J Med Chem 53: 3183-97 (2010) Article DOI: 10.1021/jm9017866 BindingDB Entry DOI: 10.7270/Q20G3M4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM50420244 (CHEMBL1628111) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of LTC4 uptake in membrane vesicle from MRP1-expressing HeLa cells | J Biol Chem 276: 6404-11 (2001) Article DOI: 10.1074/jbc.m008251200 BindingDB Entry DOI: 10.7270/Q29S1TW9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM50366524 (ESTRONE | ESTROPIPATE | Estrone 3-sulfate | Estron...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of LTC4 uptake in membrane vesicle from MRP1-expressing HeLa cells | J Biol Chem 276: 6404-11 (2001) Article DOI: 10.1074/jbc.m008251200 BindingDB Entry DOI: 10.7270/Q29S1TW9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50064025 (CHEMBL282129 | N*1*-{(2R,3R,4S,5R,6R)-3,4,5-Tris-b...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Binding affinity for human receptor subtype hSSTR4. | J Med Chem 41: 1382-91 (1998) Article DOI: 10.1021/jm9800346 BindingDB Entry DOI: 10.7270/Q28S4P2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM50420221 (CHEMBL325447) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP1-expressing HeLa cells | J Biol Chem 271: 9683-9 (1996) BindingDB Entry DOI: 10.7270/Q2PC33NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Deutsches Krebsforschungszentrum Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of GSSG uptake in membrane vesicle from MRP1-expressing HeLa cells | Biochem J 314: 433-7 (1996) Article DOI: 10.1042/bj3140433 BindingDB Entry DOI: 10.7270/Q2P271Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50064025 (CHEMBL282129 | N*1*-{(2R,3R,4S,5R,6R)-3,4,5-Tris-b...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Binding affinity for human receptor subtype hSSTR3. | J Med Chem 41: 1382-91 (1998) Article DOI: 10.1021/jm9800346 BindingDB Entry DOI: 10.7270/Q28S4P2Q | |||||||||||
More data for this Ligand-Target Pair |
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