Compile Data Set for Download or QSAR

Found 23 hits with Last Name = 'czaplewski' and Initial = 'lg'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494813 (CHEMBL3094348) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1ccc(nc1)C(O)=O Show InChI InChI=1S/C21H17N5O3S/c1-2-22-20(29)26-21-25-17-10-13(12-6-7-16(19(27)28)24-11-12)9-14(18(17)30-21)15-5-3-4-8-23-15/h3-11H,2H2,1H3,(H,27,28)(H2,22,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.38	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494804 (CHEMBL3094361) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCCC1(C)C(O)=O Show InChI InChI=1S/C25H25N7O3S/c1-3-26-23(35)31-24-30-19-12-15(11-17(20(19)36-24)18-7-4-5-9-27-18)16-13-28-22(29-14-16)32-10-6-8-25(32,2)21(33)34/h4-5,7,9,11-14H,3,6,8,10H2,1-2H3,(H,33,34)(H2,26,30,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.93	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494814 (CHEMBL3094364) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCCC(C)(CC1)C(O)=O Show InChI InChI=1S/C27H29N7O3S/c1-3-28-25(37)33-26-32-21-14-17(13-19(22(21)38-26)20-7-4-5-10-29-20)18-15-30-24(31-16-18)34-11-6-8-27(2,9-12-34)23(35)36/h4-5,7,10,13-16H,3,6,8-9,11-12H2,1-2H3,(H,35,36)(H2,28,32,33,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus)	BDBM50494811 (CHEMBL3094350) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(C)(CC1)C(O)=O Show InChI InChI=1S/C26H27N7O3S/c1-3-27-24(36)32-25-31-20-13-16(12-18(21(20)37-25)19-6-4-5-9-28-19)17-14-29-23(30-15-17)33-10-7-26(2,8-11-33)22(34)35/h4-6,9,12-15H,3,7-8,10-11H2,1-2H3,(H,34,35)(H2,27,31,32,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494811 (CHEMBL3094350) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(C)(CC1)C(O)=O Show InChI InChI=1S/C26H27N7O3S/c1-3-27-24(36)32-25-31-20-13-16(12-18(21(20)37-25)19-6-4-5-9-28-19)17-14-29-23(30-15-17)33-10-7-26(2,8-11-33)22(34)35/h4-6,9,12-15H,3,7-8,10-11H2,1-2H3,(H,34,35)(H2,27,31,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494806 (CHEMBL3094349) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(CC1)C(O)=O Show InChI InChI=1S/C25H25N7O3S/c1-2-26-24(35)31-25-30-20-12-16(11-18(21(20)36-25)19-5-3-4-8-27-19)17-13-28-23(29-14-17)32-9-6-15(7-10-32)22(33)34/h3-5,8,11-15H,2,6-7,9-10H2,1H3,(H,33,34)(H2,26,30,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494810 (CHEMBL3094351) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(CC)(CC1)C(O)=O Show InChI InChI=1S/C27H29N7O3S/c1-3-27(23(35)36)8-11-34(12-9-27)24-30-15-18(16-31-24)17-13-19(20-7-5-6-10-29-20)22-21(14-17)32-26(38-22)33-25(37)28-4-2/h5-7,10,13-16H,3-4,8-9,11-12H2,1-2H3,(H,35,36)(H2,28,32,33,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22.6	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494805 (CHEMBL3094357) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1ccc(nc1)N1CCC(C)(CC1)C(O)=O Show InChI InChI=1S/C27H28N6O3S/c1-3-28-25(36)32-26-31-21-15-18(14-19(23(21)37-26)20-6-4-5-11-29-20)17-7-8-22(30-16-17)33-12-9-27(2,10-13-33)24(34)35/h4-8,11,14-16H,3,9-10,12-13H2,1-2H3,(H,34,35)(H2,28,31,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23.2	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus)	BDBM50494806 (CHEMBL3094349) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(CC1)C(O)=O Show InChI InChI=1S/C25H25N7O3S/c1-2-26-24(35)31-25-30-20-12-16(11-18(21(20)36-25)19-5-3-4-8-27-19)17-13-28-23(29-14-17)32-9-6-15(7-10-32)22(33)34/h3-5,8,11-15H,2,6-7,9-10H2,1H3,(H,33,34)(H2,26,30,31,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23.8	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50058509 (CHEMBL3329317) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(O)cc2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C20H20N6O3/c1-2-22-20(29)26-18-10-17(24-13-5-7-15(27)8-6-13)16(12-23-18)19(28)25-14-4-3-9-21-11-14/h3-12,27H,2H2,1H3,(H,25,28)(H3,22,23,24,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus GyrB assessed reduction in DNA supercoiling activity by malachite green dye based by spectrophotometry				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494802 (CHEMBL3094353) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(CC1)(C(O)=O)C(F)(F)F Show InChI InChI=1S/C26H24F3N7O3S/c1-2-30-23(39)35-24-34-19-12-15(11-17(20(19)40-24)18-5-3-4-8-31-18)16-13-32-22(33-14-16)36-9-6-25(7-10-36,21(37)38)26(27,28)29/h3-5,8,11-14H,2,6-7,9-10H2,1H3,(H,37,38)(H2,30,34,35,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494809 (CHEMBL3094359) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cncc(c1)N1CCC(C)(CC1)C(O)=O Show InChI InChI=1S/C27H28N6O3S/c1-3-29-25(36)32-26-31-22-14-17(13-20(23(22)37-26)21-6-4-5-9-30-21)18-12-19(16-28-15-18)33-10-7-27(2,8-11-33)24(34)35/h4-6,9,12-16H,3,7-8,10-11H2,1-2H3,(H,34,35)(H2,29,31,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494812 (CHEMBL3094347) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cccnc1 Show InChI InChI=1S/C20H17N5OS/c1-2-22-19(26)25-20-24-17-11-14(13-6-5-8-21-12-13)10-15(18(17)27-20)16-7-3-4-9-23-16/h3-12H,2H2,1H3,(H2,22,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37.3	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494803 (CHEMBL3094358) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(cn1)N1CCC(C)(CC1)C(O)=O Show InChI InChI=1S/C26H27N7O3S/c1-3-27-24(36)32-25-31-19-13-16(12-17(22(19)37-25)18-6-4-5-9-28-18)20-14-30-21(15-29-20)33-10-7-26(2,8-11-33)23(34)35/h4-6,9,12-15H,3,7-8,10-11H2,1-2H3,(H,34,35)(H2,27,31,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38.6	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50058510 (CHEMBL3329319) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(OC)cc2OC)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C22H24N6O4/c1-4-24-22(30)28-20-11-18(27-17-8-7-15(31-2)10-19(17)32-3)16(13-25-20)21(29)26-14-6-5-9-23-12-14/h5-13H,4H2,1-3H3,(H,26,29)(H3,24,25,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus GyrB assessed reduction in DNA supercoiling activity by malachite green dye based by spectrophotometry				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494807 (CHEMBL3094362) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(C)(C1)C(O)=O Show InChI InChI=1S/C25H25N7O3S/c1-3-26-23(35)31-24-30-19-11-15(10-17(20(19)36-24)18-6-4-5-8-27-18)16-12-28-22(29-13-16)32-9-7-25(2,14-32)21(33)34/h4-6,8,10-13H,3,7,9,14H2,1-2H3,(H,33,34)(H2,26,30,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit B (Staphylococcus aureus)	BDBM50058509 (CHEMBL3329317) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(O)cc2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C20H20N6O3/c1-2-22-20(29)26-18-10-17(24-13-5-7-15(27)8-6-13)16(12-23-18)19(28)25-14-4-3-9-21-11-14/h3-12,27H,2H2,1H3,(H,25,28)(H3,22,23,24,26,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ParE				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50494808 (CHEMBL3094360) Show SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1nc(ns1)N1CCC(C)(CC1)C(O)=O Show InChI InChI=1S/C24H25N7O3S2/c1-3-25-22(34)29-23-27-17-13-14(12-15(18(17)35-23)16-6-4-5-9-26-16)19-28-21(30-36-19)31-10-7-24(2,8-11-31)20(32)33/h4-6,9,12-13H,3,7-8,10-11H2,1-2H3,(H,32,33)(H2,25,27,29,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Biota Holdings Ltd Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assay				Bioorg Med Chem Lett 23: 6598-603 (2013) Article DOI: 10.1016/j.bmcl.2013.10.058 BindingDB Entry DOI: 10.7270/Q2HD7ZMQ
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Prolysis Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Science 321: 1673-5 (2008) Article DOI: 10.1126/science.1159961 BindingDB Entry DOI: 10.7270/Q2HX1GG1
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 4 subunit B (Escherichia coli (strain K12))	BDBM50058511 (CHEMBL3329318) Show SMILES CCNC(=O)Nc1cc(Nc2cccc(O)c2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C20H20N6O3/c1-2-22-20(29)26-18-10-17(24-13-5-3-7-15(27)9-13)16(12-23-18)19(28)25-14-6-4-8-21-11-14/h3-12,27H,2H2,1H3,(H,25,28)(H3,22,23,24,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli ParE				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit B (Staphylococcus aureus)	BDBM50058510 (CHEMBL3329319) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(OC)cc2OC)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C22H24N6O4/c1-4-24-22(30)28-20-11-18(27-17-8-7-15(31-2)10-19(17)32-3)16(13-25-20)21(29)26-14-6-5-9-23-12-14/h5-13H,4H2,1-3H3,(H,26,29)(H3,24,25,27,28,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ParE				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit B (Escherichia coli (strain K12))	BDBM50058509 (CHEMBL3329317) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(O)cc2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C20H20N6O3/c1-2-22-20(29)26-18-10-17(24-13-5-7-15(27)8-6-13)16(12-23-18)19(28)25-14-4-3-9-21-11-14/h3-12,27H,2H2,1H3,(H,25,28)(H3,22,23,24,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli ParE				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit B (Escherichia coli (strain K12))	BDBM50058510 (CHEMBL3329319) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(OC)cc2OC)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C22H24N6O4/c1-4-24-22(30)28-20-11-18(27-17-8-7-15(31-2)10-19(17)32-3)16(13-25-20)21(29)26-14-6-5-9-23-12-14/h5-13H,4H2,1-3H3,(H,26,29)(H3,24,25,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli ParE				Eur J Med Chem 86: 31-8 (2014) Article DOI: 10.1016/j.ejmech.2014.08.025 BindingDB Entry DOI: 10.7270/Q2S75J0P
					More data for this Ligand-Target Pair