Found 22 hits with Last Name = 'denton' and Initial = 'd' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198544
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)C1c2ccccc2Oc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H28F3N5O3/c29-28(30,31)18-13-11-17(12-14-18)16-35-25(37)21(8-5-15-34-27(32)33)36-26(38)24-19-6-1-3-9-22(19)39-23-10-4-2-7-20(23)24/h1-4,6-7,9-14,21,24H,5,8,15-16H2,(H,35,37)(H,36,38)(H4,32,33,34)/t21-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198542
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)C1c2ccccc2-c2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H28F3N5O2/c29-28(30,31)18-13-11-17(12-14-18)16-35-25(37)23(10-5-15-34-27(32)33)36-26(38)24-21-8-3-1-6-19(21)20-7-2-4-9-22(20)24/h1-4,6-9,11-14,23-24H,5,10,15-16H2,(H,35,37)(H,36,38)(H4,32,33,34)/t23-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198539
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H25F3N6O2/c24-23(25,26)16-9-7-14(8-10-16)13-30-20(33)18(6-3-11-29-22(27)28)32-21(34)19-12-15-4-1-2-5-17(15)31-19/h1-2,4-5,7-10,12,18,31H,3,6,11,13H2,(H,30,33)(H,32,34)(H4,27,28,29)/t18-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198543
((R)-5-fluoro-N-(5-guanidino-1-oxo-1-(4-(trifluorom...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2cc(F)ccc2[nH]1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F4N6O2/c24-16-7-8-17-14(10-16)11-19(32-17)21(35)33-18(2-1-9-30-22(28)29)20(34)31-12-13-3-5-15(6-4-13)23(25,26)27/h3-8,10-11,18,32H,1-2,9,12H2,(H,31,34)(H,33,35)(H4,28,29,30)/t18-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198549
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2s1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N5O2S/c24-23(25,26)16-9-7-14(8-10-16)13-30-20(32)17(5-3-11-29-22(27)28)31-21(33)19-12-15-4-1-2-6-18(15)34-19/h1-2,4,6-10,12,17H,3,5,11,13H2,(H,30,32)(H,31,33)(H4,27,28,29)/t17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50241097
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H27F3N6O3/c1-36-17-8-9-18-15(11-17)12-20(32-18)22(35)33-19(3-2-10-30-23(28)29)21(34)31-13-14-4-6-16(7-5-14)24(25,26)27/h4-9,11-12,19,32H,2-3,10,13H2,1H3,(H,31,34)(H,33,35)(H4,28,29,30)/t19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198546
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cnc2ccccc2c1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H25F3N6O2/c25-24(26,27)18-9-7-15(8-10-18)13-32-22(35)20(6-3-11-30-23(28)29)33-21(34)17-12-16-4-1-2-5-19(16)31-14-17/h1-2,4-5,7-10,12,14,20H,3,6,11,13H2,(H,32,35)(H,33,34)(H4,28,29,30)/t20-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198555
((R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-(tr...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H30F3N5O2/c29-28(30,31)22-15-13-19(14-16-22)18-35-25(37)23(12-7-17-34-27(32)33)36-26(38)24(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-6,8-11,13-16,23-24H,7,12,17-18H2,(H,35,37)(H,36,38)(H4,32,33,34)/t23-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198553
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1ccc2ccccc2c1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C25H26F3N5O2/c26-25(27,28)20-11-7-16(8-12-20)15-32-23(35)21(6-3-13-31-24(29)30)33-22(34)19-10-9-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-12,14,21H,3,6,13,15H2,(H,32,35)(H,33,34)(H4,29,30,31)/t21-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 212 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198550
((R)-5-guanidino-2-(2-(naphthalen-1-yl)acetamido)-N...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)Cc1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H28F3N5O2/c27-26(28,29)20-12-10-17(11-13-20)16-33-24(36)22(9-4-14-32-25(30)31)34-23(35)15-19-7-3-6-18-5-1-2-8-21(18)19/h1-3,5-8,10-13,22H,4,9,14-16H2,(H,33,36)(H,34,35)(H4,30,31,32)/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198551
((R)-4-fluoro-N-(5-guanidino-1-oxo-1-(4-(trifluorom...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1ccc(F)c2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C25H25F4N5O2/c26-20-12-11-19(17-4-1-2-5-18(17)20)22(35)34-21(6-3-13-32-24(30)31)23(36)33-14-15-7-9-16(10-8-15)25(27,28)29/h1-2,4-5,7-12,21H,3,6,13-14H2,(H,33,36)(H,34,35)(H4,30,31,32)/t21-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198540
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2o1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N5O3/c24-23(25,26)16-9-7-14(8-10-16)13-30-20(32)17(5-3-11-29-22(27)28)31-21(33)19-12-15-4-1-2-6-18(15)34-19/h1-2,4,6-10,12,17H,3,5,11,13H2,(H,30,32)(H,31,33)(H4,27,28,29)/t17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 313 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198552
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES COc1ccc2cc(ccc2c1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H28F3N5O3/c1-37-21-11-8-17-13-19(7-6-18(17)14-21)23(35)34-22(3-2-12-32-25(30)31)24(36)33-15-16-4-9-20(10-5-16)26(27,28)29/h4-11,13-14,22H,2-3,12,15H2,1H3,(H,33,36)(H,34,35)(H4,30,31,32)/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 443 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198556
((R)-2-(2-(1H-indol-2-yl)acetamido)-5-guanidino-N-(...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)Cc1cc2ccccc2[nH]1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H27F3N6O2/c25-24(26,27)17-9-7-15(8-10-17)14-31-22(35)20(6-3-11-30-23(28)29)33-21(34)13-18-12-16-4-1-2-5-19(16)32-18/h1-2,4-5,7-10,12,20,32H,3,6,11,13-14H2,(H,31,35)(H,33,34)(H4,28,29,30)/t20-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 512 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198547
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES COc1cccc2cc(oc12)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H26F3N5O4/c1-35-18-6-2-4-15-12-19(36-20(15)18)22(34)32-17(5-3-11-30-23(28)29)21(33)31-13-14-7-9-16(10-8-14)24(25,26)27/h2,4,6-10,12,17H,3,5,11,13H2,1H3,(H,31,33)(H,32,34)(H4,28,29,30)/t17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 622 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198545
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)C1c2ccccc2Cc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C29H30F3N5O2/c30-29(31,32)21-13-11-18(12-14-21)17-36-26(38)24(10-5-15-35-28(33)34)37-27(39)25-22-8-3-1-6-19(22)16-20-7-2-4-9-23(20)25/h1-4,6-9,11-14,24-25H,5,10,15-17H2,(H,36,38)(H,37,39)(H4,33,34,35)/t24-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 763 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198541
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1ccc2ccccc2n1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H25F3N6O2/c25-24(26,27)17-10-7-15(8-11-17)14-31-21(34)19(6-3-13-30-23(28)29)33-22(35)20-12-9-16-4-1-2-5-18(16)32-20/h1-2,4-5,7-12,19H,3,6,13-14H2,(H,31,34)(H,33,35)(H4,28,29,30)/t19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 904 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198557
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1csc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N5O2S/c24-23(25,26)15-9-7-14(8-10-15)12-30-21(33)18(5-3-11-29-22(27)28)31-20(32)17-13-34-19-6-2-1-4-16(17)19/h1-2,4,6-10,13,18H,3,5,11-12H2,(H,30,33)(H,31,32)(H4,27,28,29)/t18-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 952 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50241098
((R)-2-(2-(benzo[b]thiophen-3-yl)acetamido)-5-guani...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)Cc1csc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H26F3N5O2S/c25-24(26,27)17-9-7-15(8-10-17)13-31-22(34)19(5-3-11-30-23(28)29)32-21(33)12-16-14-35-20-6-2-1-4-18(16)20/h1-2,4,6-10,14,19H,3,5,11-13H2,(H,31,34)(H,32,33)(H4,28,29,30)/t19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198554
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1ccnc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H25F3N6O2/c25-24(26,27)16-9-7-15(8-10-16)14-32-22(35)20(6-3-12-31-23(28)29)33-21(34)18-11-13-30-19-5-2-1-4-17(18)19/h1-2,4-5,7-11,13,20H,3,6,12,14H2,(H,32,35)(H,33,34)(H4,28,29,31)/t20-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198548
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C25H26F3N5O2/c26-25(27,28)18-12-10-16(11-13-18)15-32-23(35)21(9-4-14-31-24(29)30)33-22(34)20-8-3-6-17-5-1-2-7-19(17)20/h1-3,5-8,10-13,21H,4,9,14-15H2,(H,32,35)(H,33,34)(H4,29,30,31)/t21-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM50198558
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cc2ccccc2cn1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H25F3N6O2/c25-24(26,27)18-9-7-15(8-10-18)13-32-21(34)19(6-3-11-30-23(28)29)33-22(35)20-12-16-4-1-2-5-17(16)14-31-20/h1-2,4-5,7-10,12,14,19H,3,6,11,13H2,(H,32,34)(H,33,35)(H4,28,29,30)/t19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
| Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 832-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT |
More data for this
Ligand-Target Pair | |
Search and Browse
