Compile Data Set for Download or QSAR

Found 67 hits with Last Name = 'dodge' and Initial = 'me'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-2 (Mus musculus (Mouse))	BDBM36414 (CID15993586 | trans-N-Benzyl-4-((1-((2-cyanophenyl...) Show SMILES [H][C@]1(Cn2c(=O)n(Cc3ccccc3C#N)c3ccccc3c2=O)CC[C@@]([H])(CC1)C(=O)NCc1ccccc1 |r,wU:1.1,26.29,wD:1.0,26.33,(-1.18,-1.6,;0,-2.59,;-1.54,-2.59,;-2.31,-1.26,;-3.85,-1.26,;-4.61,-2.59,;-4.62,.07,;-6.15,.07,;-6.92,1.4,;-6.15,2.74,;-6.92,4.07,;-8.46,4.07,;-9.23,2.74,;-8.46,1.4,;-9.23,.07,;-10,-1.26,;-3.85,1.41,;-4.62,2.74,;-3.85,4.08,;-2.31,4.08,;-1.54,2.74,;-2.31,1.41,;-1.54,.07,;,.07,;.77,-1.25,;2.31,-1.25,;3.08,-2.59,;3.94,-3.87,;2.31,-3.92,;.77,-3.92,;4.62,-2.59,;5.38,-1.26,;5.38,-3.92,;6.92,-3.92,;7.69,-2.59,;6.92,-1.25,;7.69,.08,;9.23,.08,;10,-1.25,;9.23,-2.59,)| Show InChI InChI=1S/C31H30N4O3/c32-18-25-10-4-5-11-26(25)21-34-28-13-7-6-12-27(28)30(37)35(31(34)38)20-23-14-16-24(17-15-23)29(36)33-19-22-8-2-1-3-9-22/h1-13,23-24H,14-17,19-21H2,(H,33,36)/t23-,24-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM36412 (CID25093486 | N-(4-Methylquinolin-8-yl)-4-(endo-4-...) Show SMILES [H][C@]12C[C@]([H])(C=C1)c1c(O)n(c(O)c21)-c1ccc(cc1)C(=O)Nc1cccc2c(C)ccnc12 |c:5| Show InChI InChI=1S/C26H21N3O3/c1-14-11-12-27-23-19(14)3-2-4-20(23)28-24(30)15-7-9-18(10-8-15)29-25(31)21-16-5-6-17(13-16)22(21)26(29)32/h2-12,16-17,31-32H,13H2,1H3,(H,28,30)/t16-,17+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM36413 (CID15995771 | trans-N-Benzyl-4-((1-((6-methyl-4-ox...) Show SMILES [H][C@]1(Cn2c(=O)n(Cc3cc(=O)n4c(C)cccc4n3)c3ccccc3c2=O)CC[C@@]([H])(CC1)C(=O)NCc1ccccc1 |r,wU:1.1,30.34,wD:1.0,30.38,(-.8,-3.01,;.38,-4,;-1.16,-4,;-1.92,-2.67,;-3.46,-2.67,;-4.23,-4,;-4.23,-1.33,;-5.77,-1.33,;-6.54,-0,;-8.08,-0,;-8.85,1.33,;-10.38,1.33,;-8.08,2.66,;-8.85,4,;-10.38,4,;-8.08,5.33,;-6.54,5.33,;-5.77,4,;-6.54,2.66,;-5.77,1.33,;-3.46,0,;-4.23,1.33,;-3.46,2.67,;-1.92,2.67,;-1.15,1.33,;-1.92,0,;-1.15,-1.33,;.38,-1.33,;1.15,-2.66,;2.69,-2.66,;3.46,-4,;4.33,-5.27,;2.69,-5.33,;1.15,-5.33,;5,-4,;5.77,-2.67,;5.77,-5.33,;7.3,-5.33,;8.07,-4,;7.3,-2.66,;8.07,-1.33,;9.61,-1.33,;10.38,-2.66,;9.61,-4,)| Show InChI InChI=1S/C33H33N5O4/c1-22-8-7-13-29-35-26(18-30(39)38(22)29)21-36-28-12-6-5-11-27(28)32(41)37(33(36)42)20-24-14-16-25(17-15-24)31(40)34-19-23-9-3-2-4-10-23/h2-13,18,24-25H,14-17,19-21H2,1H3,(H,34,40)/t24-,25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM50294835 (4-((1S,2S,6R,7R)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...) Show SMILES Oc1c2[C@H]3C[C@H](C=C3)c2c(O)n1-c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r,c:6| Show InChI InChI=1S/C25H19N3O3/c29-23(27-19-5-1-3-14-4-2-12-26-22(14)19)15-8-10-18(11-9-15)28-24(30)20-16-6-7-17(13-16)21(20)25(28)31/h1-12,16-17,30-31H,13H2,(H,27,29)/t16-,17+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50427998 (CHEMBL2322630) Show SMILES COc1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccccc4)c(=O)c4ccccc34)sc2c1 Show InChI InChI=1S/C25H19N5O4S/c1-34-16-11-12-19-20(13-16)35-25(27-19)28-21(31)14-26-23(32)22-17-9-5-6-10-18(17)24(33)30(29-22)15-7-3-2-4-8-15/h2-13H,14H2,1H3,(H,26,32)(H,27,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50427999 (CHEMBL2322629) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(cn1)-c1ccco1 Show InChI InChI=1S/C22H17N5O3S2/c28-18(26-21-23-11-14(12-24-21)17-7-4-9-30-17)13-32-22-25-16-8-10-31-19(16)20(29)27(22)15-5-2-1-3-6-15/h1-7,9,11-12H,8,10,13H2,(H,23,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428000 (CHEMBL2322628) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(cn1)-c1ccoc1 Show InChI InChI=1S/C22H17N5O3S2/c28-18(26-21-23-10-15(11-24-21)14-6-8-30-12-14)13-32-22-25-17-7-9-31-19(17)20(29)27(22)16-4-2-1-3-5-16/h1-6,8,10-12H,7,9,13H2,(H,23,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428001 (CHEMBL2322627) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1cccs1 Show InChI InChI=1S/C23H18N4O2S3/c28-20(26-19-9-8-15(13-24-19)18-7-4-11-30-18)14-32-23-25-17-10-12-31-21(17)22(29)27(23)16-5-2-1-3-6-16/h1-9,11,13H,10,12,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428002 (CHEMBL2322626) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccsc1 Show InChI InChI=1S/C23H18N4O2S3/c28-20(26-19-7-6-15(12-24-19)16-8-10-30-13-16)14-32-23-25-18-9-11-31-21(18)22(29)27(23)17-4-2-1-3-5-17/h1-8,10,12-13H,9,11,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428003 (CHEMBL2322625) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccco1 Show InChI InChI=1S/C23H18N4O3S2/c28-20(26-19-9-8-15(13-24-19)18-7-4-11-30-18)14-32-23-25-17-10-12-31-21(17)22(29)27(23)16-5-2-1-3-6-16/h1-9,11,13H,10,12,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428004 (CHEMBL2322624) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccoc1 Show InChI InChI=1S/C23H18N4O3S2/c28-20(26-19-7-6-15(12-24-19)16-8-10-30-13-16)14-32-23-25-18-9-11-31-21(18)22(29)27(23)17-4-2-1-3-5-17/h1-8,10,12-13H,9,11,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428005 (CHEMBL2322623) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1cncnc1 Show InChI InChI=1S/C23H18N6O2S2/c30-20(28-19-7-6-15(12-26-19)16-10-24-14-25-11-16)13-33-23-27-18-8-9-32-21(18)22(31)29(23)17-4-2-1-3-5-17/h1-7,10-12,14H,8-9,13H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428006 (CHEMBL2323233) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1cccnc1 Show InChI InChI=1S/C24H19N5O2S2/c30-21(28-20-9-8-17(14-26-20)16-5-4-11-25-13-16)15-33-24-27-19-10-12-32-22(19)23(31)29(24)18-6-2-1-3-7-18/h1-9,11,13-14H,10,12,15H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428007 (CHEMBL2323232) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(cn1)-c1ccccc1 Show InChI InChI=1S/C24H19N5O2S2/c30-20(28-23-25-13-17(14-26-23)16-7-3-1-4-8-16)15-33-24-27-19-11-12-32-21(19)22(31)29(24)18-9-5-2-6-10-18/h1-10,13-14H,11-12,15H2,(H,25,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428008 (CHEMBL2323231) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(28-21-12-11-18(15-26-21)17-7-3-1-4-8-17)16-33-25-27-20-13-14-32-23(20)24(31)29(25)19-9-5-2-6-10-19/h1-12,15H,13-14,16H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428009 (CHEMBL2323230) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(nc1)-c1ccccc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-18-11-12-20(26-15-18)17-7-3-1-4-8-17)16-33-25-28-21-13-14-32-23(21)24(31)29(25)19-9-5-2-6-10-19/h1-12,15H,13-14,16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428010 (CHEMBL2323229) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-19-8-6-17(7-9-19)18-10-13-26-14-11-18)16-33-25-28-21-12-15-32-23(21)24(31)29(25)20-4-2-1-3-5-20/h1-11,13-14H,12,15-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428011 (CHEMBL2323228) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-19-10-8-17(9-11-19)18-5-4-13-26-15-18)16-33-25-28-21-12-14-32-23(21)24(31)29(25)20-6-2-1-3-7-20/h1-11,13,15H,12,14,16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.450	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428012 (CHEMBL2322635) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-18-11-9-17(10-12-18)20-8-4-5-14-26-20)16-33-25-28-21-13-15-32-23(21)24(31)29(25)19-6-2-1-3-7-19/h1-12,14H,13,15-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428013 (CHEMBL2322634) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccccc1-c1ccccc1 Show InChI InChI=1S/C26H21N3O2S2/c30-23(27-21-14-8-7-13-20(21)18-9-3-1-4-10-18)17-33-26-28-22-15-16-32-24(22)25(31)29(26)19-11-5-2-6-12-19/h1-14H,15-17H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428014 (CHEMBL2322633) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C26H21N3O2S2/c30-23(27-20-11-7-10-19(16-20)18-8-3-1-4-9-18)17-33-26-28-22-14-15-32-24(22)25(31)29(26)21-12-5-2-6-13-21/h1-13,16H,14-15,17H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428015 (CHEMBL2322632) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H21N3O2S2/c30-23(27-20-13-11-19(12-14-20)18-7-3-1-4-8-18)17-33-26-28-22-15-16-32-24(22)25(31)29(26)21-9-5-2-6-10-21/h1-14H,15-17H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428016 (CHEMBL2323243) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C25H26N4O2S2/c30-22(26-18-9-11-19(12-10-18)28-14-5-2-6-15-28)17-33-25-27-21-13-16-32-23(21)24(31)29(25)20-7-3-1-4-8-20/h1,3-4,7-12H,2,5-6,13-17H2,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428017 (CHEMBL2323242) Show SMILES CN(C)c1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2-c2ccccc2)cc1 Show InChI InChI=1S/C22H22N4O2S2/c1-25(2)16-10-8-15(9-11-16)23-19(27)14-30-22-24-18-12-13-29-20(18)21(28)26(22)17-6-4-3-5-7-17/h3-11H,12-14H2,1-2H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428018 (CHEMBL2323241) Show SMILES CC(=O)c1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2-c2ccccc2)cc1 Show InChI InChI=1S/C22H19N3O3S2/c1-14(26)15-7-9-16(10-8-15)23-19(27)13-30-22-24-18-11-12-29-20(18)21(28)25(22)17-5-3-2-4-6-17/h2-10H,11-13H2,1H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428019 (CHEMBL2323240) Show SMILES CCOc1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2-c2ccccc2)cc1 Show InChI InChI=1S/C22H21N3O3S2/c1-2-28-17-10-8-15(9-11-17)23-19(26)14-30-22-24-18-12-13-29-20(18)21(27)25(22)16-6-4-3-5-7-16/h3-11H,2,12-14H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428020 (CHEMBL2323239) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(s1)-c1ccccc1 Show InChI InChI=1S/C23H18N4O2S3/c28-19(26-22-24-13-18(32-22)15-7-3-1-4-8-15)14-31-23-25-17-11-12-30-20(17)21(29)27(23)16-9-5-2-6-10-16/h1-10,13H,11-12,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428021 (CHEMBL2323238) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C23H18N4O2S3/c28-19(26-22-24-18(13-31-22)15-7-3-1-4-8-15)14-32-23-25-17-11-12-30-20(17)21(29)27(23)16-9-5-2-6-10-16/h1-10,13H,11-12,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428022 (CHEMBL2323237) Show SMILES COc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)ccc2c1 Show InChI InChI=1S/C24H20N4O3S2/c1-31-17-8-9-18-15(13-17)7-10-20(25-18)27-21(29)14-33-24-26-19-11-12-32-22(19)23(30)28(24)16-5-3-2-4-6-16/h2-10,13H,11-12,14H2,1H3,(H,25,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428023 (CHEMBL2323236) Show SMILES COc1ccc2nc(NC(=O)CNC(=O)c3ccc(=O)n(c3)-c3ccccc3)sc2c1 Show InChI InChI=1S/C22H18N4O4S/c1-30-16-8-9-17-18(11-16)31-22(24-17)25-19(27)12-23-21(29)14-7-10-20(28)26(13-14)15-5-3-2-4-6-15/h2-11,13H,12H2,1H3,(H,23,29)(H,24,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428024 (CHEMBL2323235) Show SMILES O=C(CNC(=O)c1nn(-c2ccccc2)c(=O)c2ccccc12)Nc1nccs1 Show InChI InChI=1S/C20H15N5O3S/c26-16(23-20-21-10-11-29-20)12-22-18(27)17-14-8-4-5-9-15(14)19(28)25(24-17)13-6-2-1-3-7-13/h1-11H,12H2,(H,22,27)(H,21,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428025 (CHEMBL2323234) Show SMILES CCOC(=O)c1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2-c2ccccc2)cc1 Show InChI InChI=1S/C23H21N3O4S2/c1-2-30-22(29)15-8-10-16(11-9-15)24-19(27)14-32-23-25-18-12-13-31-20(18)21(28)26(23)17-6-4-3-5-7-17/h3-11H,2,12-14H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428026 (CHEMBL1444402) Show SMILES CCn1c(SCC(=O)Nc2nc3ccccc3s2)nc2CC(C)Sc2c1=O Show InChI InChI=1S/C18H18N4O2S3/c1-3-22-16(24)15-12(8-10(2)26-15)20-18(22)25-9-14(23)21-17-19-11-6-4-5-7-13(11)27-17/h4-7,10H,3,8-9H2,1-2H3,(H,19,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM37088 (2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno...) Show SMILES CC1Cc2nc(SCC(=O)Nc3nc4ccc(C)cc4s3)n(C)c(=O)c2S1 Show InChI InChI=1S/C18H18N4O2S3/c1-9-4-5-11-13(6-9)27-17(19-11)21-14(23)8-25-18-20-12-7-10(2)26-15(12)16(24)22(18)3/h4-6,10H,7-8H2,1-3H3,(H,19,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428027 (CHEMBL1257090) Show SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(C)cc3s2)nc2CCSc2c1=O |(3.46,-37.28,;2.64,-35.97,;3.36,-34.61,;4.9,-34.56,;5.62,-33.19,;4.79,-31.89,;3.26,-31.95,;2.54,-33.31,;1.01,-33.36,;.18,-32.06,;.9,-30.7,;2.44,-30.65,;3.16,-29.28,;4.7,-29.23,;2.34,-27.98,;.8,-28.04,;-.15,-26.82,;-1.59,-27.36,;-2.95,-26.64,;-4.25,-27.46,;-4.19,-29,;-5.49,-29.82,;-2.83,-29.71,;-1.54,-28.9,;-.06,-29.32,;-1.36,-32.12,;-2.08,-33.46,;-3.58,-33.83,;-3.7,-35.38,;-2.26,-35.96,;-1.26,-34.78,;.28,-34.72,;1.09,-36.03,)| Show InChI InChI=1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50365355 (CHEMBL1257089) Show SMILES Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccc(F)cc3)sc2c1 Show InChI InChI=1S/C22H17FN4O2S3/c1-12-2-7-15-17(10-12)32-21(24-15)26-18(28)11-31-22-25-16-8-9-30-19(16)20(29)27(22)14-5-3-13(23)4-6-14/h2-7,10H,8-9,11H2,1H3,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428028 (CHEMBL1257064) Show SMILES Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1 Show InChI InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428029 (CHEMBL1257063) Show SMILES COc1ccc(cc1)-n1nc(C(=O)NCC(=O)Nc2nc3ccc(OC)cc3s2)c2ccccc2c1=O Show InChI InChI=1S/C26H21N5O5S/c1-35-16-9-7-15(8-10-16)31-25(34)19-6-4-3-5-18(19)23(30-31)24(33)27-14-22(32)29-26-28-20-12-11-17(36-2)13-21(20)37-26/h3-13H,14H2,1-2H3,(H,27,33)(H,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428030 (CHEMBL2325508) Show SMILES CCOC(=O)c1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccccc4)c(=O)c4ccccc34)sc2c1 Show InChI InChI=1S/C27H21N5O5S/c1-2-37-26(36)16-12-13-20-21(14-16)38-27(29-20)30-22(33)15-28-24(34)23-18-10-6-7-11-19(18)25(35)32(31-23)17-8-4-3-5-9-17/h3-14H,2,15H2,1H3,(H,28,34)(H,29,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428031 (CHEMBL2325507) Show SMILES [O-][N+](=O)c1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccccc4)c(=O)c4ccccc34)sc2c1 Show InChI InChI=1S/C24H16N6O5S/c31-20(27-24-26-18-11-10-15(30(34)35)12-19(18)36-24)13-25-22(32)21-16-8-4-5-9-17(16)23(33)29(28-21)14-6-2-1-3-7-14/h1-12H,13H2,(H,25,32)(H,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428032 (CHEMBL2325506) Show SMILES COc1ccc(cc1)-n1c(SCC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)nc2CCSc2c1=O Show InChI InChI=1S/C23H17F3N4O3S3/c1-33-14-5-3-13(4-6-14)30-20(32)19-16(8-9-34-19)28-22(30)35-11-18(31)29-21-27-15-7-2-12(23(24,25)26)10-17(15)36-21/h2-7,10H,8-9,11H2,1H3,(H,27,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428033 (CHEMBL2325505) Show SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)nc2CCSc2c1=O |(46.71,-19.26,;45.38,-20.03,;45.39,-21.58,;46.72,-22.34,;46.73,-23.89,;45.4,-24.66,;44.06,-23.89,;44.06,-22.35,;42.73,-21.58,;42.73,-20.03,;44.06,-19.25,;44.05,-17.71,;45.39,-16.94,;45.38,-15.4,;46.72,-17.7,;48.05,-16.93,;49.46,-17.55,;50.48,-16.4,;52.02,-16.4,;52.78,-15.06,;52,-13.73,;50.47,-13.74,;49.71,-15.07,;48.2,-15.39,;52.76,-12.39,;54.3,-12.38,;51.98,-11.06,;53.52,-11.05,;41.39,-19.26,;40.05,-20.04,;38.59,-19.57,;37.69,-20.82,;38.6,-22.06,;40.06,-21.58,;41.39,-22.35,;41.39,-23.89,)| Show InChI InChI=1S/C23H17F3N4O3S3/c1-33-16-5-3-2-4-15(16)30-20(32)19-14(8-9-34-19)28-22(30)35-11-18(31)29-21-27-13-7-6-12(23(24,25)26)10-17(13)36-21/h2-7,10H,8-9,11H2,1H3,(H,27,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428034 (CHEMBL2324267) Show SMILES Fc1ccc(cc1)-n1c(SCC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)nc2CCSc2c1=O Show InChI InChI=1S/C22H14F4N4O2S3/c23-12-2-4-13(5-3-12)30-19(32)18-15(7-8-33-18)28-21(30)34-10-17(31)29-20-27-14-6-1-11(22(24,25)26)9-16(14)35-20/h1-6,9H,7-8,10H2,(H,27,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428035 (CHEMBL2324266) Show SMILES FC(F)(F)c1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1 Show InChI InChI=1S/C22H15F3N4O2S3/c23-22(24,25)12-6-7-14-16(10-12)34-20(26-14)28-17(30)11-33-21-27-15-8-9-32-18(15)19(31)29(21)13-4-2-1-3-5-13/h1-7,10H,8-9,11H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428036 (CHEMBL2324265) Show SMILES Fc1ccc(cc1)-n1nc(C(=O)NCC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)c2ccccc2c1=O Show InChI InChI=1S/C25H15F4N5O3S/c26-14-6-8-15(9-7-14)34-23(37)17-4-2-1-3-16(17)21(33-34)22(36)30-12-20(35)32-24-31-18-10-5-13(25(27,28)29)11-19(18)38-24/h1-11H,12H2,(H,30,36)(H,31,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428037 (CHEMBL2325513) Show SMILES FC(F)(F)c1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccccc4)c(=O)c4ccccc34)sc2c1 Show InChI InChI=1S/C25H16F3N5O3S/c26-25(27,28)14-10-11-18-19(12-14)37-24(30-18)31-20(34)13-29-22(35)21-16-8-4-5-9-17(16)23(36)33(32-21)15-6-2-1-3-7-15/h1-12H,13H2,(H,29,35)(H,30,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428038 (CHEMBL2325512) Show SMILES COc1ccc(cc1)-n1c(SCC(=O)Nc2nc3ccc(Cl)cc3s2)nc2CCSc2c1=O Show InChI InChI=1S/C22H17ClN4O3S3/c1-30-14-5-3-13(4-6-14)27-20(29)19-16(8-9-31-19)25-22(27)32-11-18(28)26-21-24-15-7-2-12(23)10-17(15)33-21/h2-7,10H,8-9,11H2,1H3,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428039 (CHEMBL2325511) Show SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(Cl)cc3s2)nc2CCSc2c1=O |(29.25,-7.08,;27.92,-7.85,;27.92,-9.39,;29.26,-10.16,;29.27,-11.7,;27.93,-12.48,;26.6,-11.71,;26.6,-10.17,;25.27,-9.4,;25.26,-7.85,;26.59,-7.07,;26.59,-5.53,;27.92,-4.75,;27.91,-3.21,;29.26,-5.52,;30.59,-4.74,;31.99,-5.37,;33.01,-4.22,;34.55,-4.21,;35.32,-2.88,;34.53,-1.55,;35.3,-.21,;33,-1.56,;32.24,-2.89,;30.74,-3.21,;23.92,-7.08,;22.59,-7.86,;21.12,-7.39,;20.22,-8.64,;21.13,-9.88,;22.59,-9.4,;23.93,-10.17,;23.93,-11.71,)| Show InChI InChI=1S/C22H17ClN4O3S3/c1-30-16-5-3-2-4-15(16)27-20(29)19-14(8-9-31-19)25-22(27)32-11-18(28)26-21-24-13-7-6-12(23)10-17(13)33-21/h2-7,10H,8-9,11H2,1H3,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428040 (CHEMBL2325510) Show SMILES Fc1ccc(cc1)-n1c(SCC(=O)Nc2nc3ccc(Cl)cc3s2)nc2CCSc2c1=O Show InChI InChI=1S/C21H14ClFN4O2S3/c22-11-1-6-14-16(9-11)32-20(24-14)26-17(28)10-31-21-25-15-7-8-30-18(15)19(29)27(21)13-4-2-12(23)3-5-13/h1-6,9H,7-8,10H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	175	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428041 (CHEMBL2325509) Show SMILES Clc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1 Show InChI InChI=1S/C21H15ClN4O2S3/c22-12-6-7-14-16(10-12)31-20(23-14)25-17(27)11-30-21-24-15-8-9-29-18(15)19(28)26(21)13-4-2-1-3-5-13/h1-7,10H,8-9,11H2,(H,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair

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