Compile Data Set for Download or QSAR

Found 76 hits with Last Name = 'dwivedi' and Initial = 'ak'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524365 (CHEMBL4579211) Show SMILES C(CN1CCCCC1)Oc1ccc(Nc2nccc(NCc3ccccc3)n2)cc1 Show InChI InChI=1S/C24H29N5O/c1-3-7-20(8-4-1)19-26-23-13-14-25-24(28-23)27-21-9-11-22(12-10-21)30-18-17-29-15-5-2-6-16-29/h1,3-4,7-14H,2,5-6,15-19H2,(H2,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human H3 receptor expressed in HEK293T cells measured after 90 mins by liquid scintillat...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524374 (CHEMBL4453810) Show SMILES Cc1ccc(nc1)C1(O)CCN(CC1)c1nc(C)nc2ccsc12 Show InChI InChI=1S/C18H20N4OS/c1-12-3-4-15(19-11-12)18(23)6-8-22(9-7-18)17-16-14(5-10-24-16)20-13(2)21-17/h3-5,10-11,23H,6-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human H3 receptor expressed in HEK293T cells measured after 90 mins by liquid scintillat...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035670 (CHEMBL3338456) Show SMILES NNC(=O)CC(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C9H9ClFN3O2/c10-6-3-5(1-2-7(6)11)13-8(15)4-9(16)14-12/h1-3H,4,12H2,(H,13,15)(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035656 (CHEMBL1986389) Show SMILES NNC(=O)CC(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C10H11N3O4/c11-13-9(15)5-8(14)12-7-3-1-6(2-4-7)10(16)17/h1-4H,5,11H2,(H,12,14)(H,13,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035662 (CHEMBL3338464) Show SMILES COc1ccc(NC(=O)CC(=O)NN)c(OC)c1 Show InChI InChI=1S/C11H15N3O4/c1-17-7-3-4-8(9(5-7)18-2)13-10(15)6-11(16)14-12/h3-5H,6,12H2,1-2H3,(H,13,15)(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035666 (CHEMBL3338460) Show SMILES NNC(=O)CC(=O)Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C9H9N5O6/c10-12-9(16)4-8(15)11-6-2-1-5(13(17)18)3-7(6)14(19)20/h1-3H,4,10H2,(H,11,15)(H,12,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035663 (CHEMBL3338463) Show SMILES COc1ccc(OC)c(NC(=O)CC(=O)NN)c1 Show InChI InChI=1S/C11H15N3O4/c1-17-7-3-4-9(18-2)8(5-7)13-10(15)6-11(16)14-12/h3-5H,6,12H2,1-2H3,(H,13,15)(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035657 (CHEMBL3338469) Show SMILES NNC(=O)CC(=O)Nc1ccccc1C(O)=O Show InChI InChI=1S/C10H11N3O4/c11-13-9(15)5-8(14)12-7-4-2-1-3-6(7)10(16)17/h1-4H,5,11H2,(H,12,14)(H,13,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035658 (CHEMBL3338468) Show SMILES NNC(=O)CC(=O)Nc1ccc(cc1)S(O)(=O)=O Show InChI InChI=1S/C9H11N3O5S/c10-12-9(14)5-8(13)11-6-1-3-7(4-2-6)18(15,16)17/h1-4H,5,10H2,(H,11,13)(H,12,14)(H,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	7.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035665 (CHEMBL3338461) Show SMILES NNC(=O)CC(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C9H9Cl2N3O2/c10-5-1-6(11)3-7(2-5)13-8(15)4-9(16)14-12/h1-3H,4,12H2,(H,13,15)(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035659 (CHEMBL3338467) Show SMILES CCCc1ccc(NC(=O)CC(=O)NN)cc1 Show InChI InChI=1S/C12H17N3O2/c1-2-3-9-4-6-10(7-5-9)14-11(16)8-12(17)15-13/h4-7H,2-3,8,13H2,1H3,(H,14,16)(H,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035664 (CHEMBL3338462) Show SMILES NNC(=O)CC(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C9H9Cl2N3O2/c10-6-2-1-5(3-7(6)11)13-8(15)4-9(16)14-12/h1-3H,4,12H2,(H,13,15)(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035667 (CHEMBL3338459) Show SMILES NNC(=O)CC(=O)Nc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C9H10N4O4/c10-12-9(15)5-8(14)11-6-1-3-7(4-2-6)13(16)17/h1-4H,5,10H2,(H,11,14)(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035668 (CHEMBL3338458) Show SMILES NNC(=O)CC(=O)Nc1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C9H10N4O4/c10-12-9(15)5-8(14)11-6-2-1-3-7(4-6)13(16)17/h1-4H,5,10H2,(H,11,14)(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035661 (CHEMBL3338465) Show SMILES CCN(CC)c1ccc(NC(=O)CC(=O)NN)cc1 Show InChI InChI=1S/C13H20N4O2/c1-3-17(4-2)11-7-5-10(6-8-11)15-12(18)9-13(19)16-14/h5-8H,3-4,9,14H2,1-2H3,(H,15,18)(H,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035655 (CHEMBL3338470) Show SMILES NNC(=O)CC(=O)NCc1ccco1 Show InChI InChI=1S/C8H11N3O3/c9-11-8(13)4-7(12)10-5-6-2-1-3-14-6/h1-3H,4-5,9H2,(H,10,12)(H,11,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035669 (CHEMBL3338457) Show SMILES NNC(=O)CC(=O)Nc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C9H10N4O4/c10-12-9(15)5-8(14)11-6-3-1-2-4-7(6)13(16)17/h1-4H,5,10H2,(H,11,14)(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PknB (Mycobacterium tuberculosis)	BDBM50035660 (CHEMBL3338466) Show SMILES CCCCc1ccc(NC(=O)CC(=O)NN)cc1 Show InChI InChI=1S/C13H19N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12(17)9-13(18)16-14/h5-8H,2-4,9,14H2,1H3,(H,15,17)(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.65E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PknB				Bioorg Med Chem Lett 24: 5181-4 (2014) Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524380 (CHEMBL4451233) Show SMILES COc1ccc(cc1)-c1nc(N)nc2C(C)CCCc12 Show InChI InChI=1S/C16H19N3O/c1-10-4-3-5-13-14(10)18-16(17)19-15(13)11-6-8-12(20-2)9-7-11/h6-10H,3-5H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524380 (CHEMBL4451233) Show SMILES COc1ccc(cc1)-c1nc(N)nc2C(C)CCCc12 Show InChI InChI=1S/C16H19N3O/c1-10-4-3-5-13-14(10)18-16(17)19-15(13)11-6-8-12(20-2)9-7-11/h6-10H,3-5H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Cholecystokinin receptor type A (Homo sapiens (Human))	BDBM50524379 (CHEMBL4540275) Show SMILES COc1ccc(c(OC)c1)-c1nc(NC(=O)c2cc3ccccc3n2CC(O)=O)ncc1CC1CCCCC1 Show InChI InChI=1S/C30H32N4O5/c1-38-22-12-13-23(26(16-22)39-2)28-21(14-19-8-4-3-5-9-19)17-31-30(32-28)33-29(37)25-15-20-10-6-7-11-24(20)34(25)18-27(35)36/h6-7,10-13,15-17,19H,3-5,8-9,14,18H2,1-2H3,(H,35,36)(H,31,32,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Displacement of [I125]bolton hunter-CCK-8S from recombinant human CCK1 receptor expressed in stable CHO cells measured after 1 to 2 hrs by microscint...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524368 (CHEMBL4452406) Show SMILES COc1cccc(c1)-c1nc(N)nc2C(C)CCCc12 Show InChI InChI=1S/C16H19N3O/c1-10-5-3-8-13-14(10)18-16(17)19-15(13)11-6-4-7-12(9-11)20-2/h4,6-7,9-10H,3,5,8H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524368 (CHEMBL4452406) Show SMILES COc1cccc(c1)-c1nc(N)nc2C(C)CCCc12 Show InChI InChI=1S/C16H19N3O/c1-10-5-3-8-13-14(10)18-16(17)19-15(13)11-6-4-7-12(9-11)20-2/h4,6-7,9-10H,3,5,8H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524367 (CHEMBL4580450) Show SMILES CC1CCCc2c1nc(N)nc2-c1cccc(Br)c1 Show InChI InChI=1S/C15H16BrN3/c1-9-4-2-7-12-13(9)18-15(17)19-14(12)10-5-3-6-11(16)8-10/h3,5-6,8-9H,2,4,7H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524367 (CHEMBL4580450) Show SMILES CC1CCCc2c1nc(N)nc2-c1cccc(Br)c1 Show InChI InChI=1S/C15H16BrN3/c1-9-4-2-7-12-13(9)18-15(17)19-14(12)10-5-3-6-11(16)8-10/h3,5-6,8-9H,2,4,7H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524363 (CHEMBL4585616) Show SMILES CC1CCCc2c1nc(N)nc2C1CCCCC1 Show InChI InChI=1S/C15H23N3/c1-10-6-5-9-12-13(10)17-15(16)18-14(12)11-7-3-2-4-8-11/h10-11H,2-9H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524363 (CHEMBL4585616) Show SMILES CC1CCCc2c1nc(N)nc2C1CCCCC1 Show InChI InChI=1S/C15H23N3/c1-10-6-5-9-12-13(10)17-15(16)18-14(12)11-7-3-2-4-8-11/h10-11H,2-9H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50117930 ((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...) Show SMILES Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1 Show InChI InChI=1S/C21H27N3O3S/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27/h3-9,18,23H,10-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of tracer Red binding to human ERG expressed in membranes after 3 hrs by fluorescence polarization assay				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524371 (CHEMBL4456972) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(F)cc1 Show InChI InChI=1S/C15H16FN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524371 (CHEMBL4456972) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(F)cc1 Show InChI InChI=1S/C15H16FN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524366 (CHEMBL4576986) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H16ClN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524366 (CHEMBL4576986) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H16ClN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	912	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524364 (CHEMBL4563363) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccccc1 Show InChI InChI=1S/C15H17N3/c1-10-6-5-9-12-13(10)17-15(16)18-14(12)11-7-3-2-4-8-11/h2-4,7-8,10H,5-6,9H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524364 (CHEMBL4563363) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccccc1 Show InChI InChI=1S/C15H17N3/c1-10-6-5-9-12-13(10)17-15(16)18-14(12)11-7-3-2-4-8-11/h2-4,7-8,10H,5-6,9H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524381 (CHEMBL4526205) Show SMILES CC1CCCc2c1nc(N)nc2-c1cccc2ccccc12 Show InChI InChI=1S/C19H19N3/c1-12-6-4-11-16-17(12)21-19(20)22-18(16)15-10-5-8-13-7-2-3-9-14(13)15/h2-3,5,7-10,12H,4,6,11H2,1H3,(H2,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524381 (CHEMBL4526205) Show SMILES CC1CCCc2c1nc(N)nc2-c1cccc2ccccc12 Show InChI InChI=1S/C19H19N3/c1-12-6-4-11-16-17(12)21-19(20)22-18(16)15-10-5-8-13-7-2-3-9-14(13)15/h2-3,5,7-10,12H,4,6,11H2,1H3,(H2,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524370 (CHEMBL4568452) Show SMILES COc1ccc(cc1)-c1nc(N)nc2CCCCc12 Show InChI InChI=1S/C15H17N3O/c1-19-11-8-6-10(7-9-11)14-12-4-2-3-5-13(12)17-15(16)18-14/h6-9H,2-5H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524370 (CHEMBL4568452) Show SMILES COc1ccc(cc1)-c1nc(N)nc2CCCCc12 Show InChI InChI=1S/C15H17N3O/c1-19-11-8-6-10(7-9-11)14-12-4-2-3-5-13(12)17-15(16)18-14/h6-9H,2-5H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524362 (CHEMBL4467878) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(C)cc1 Show InChI InChI=1S/C16H19N3/c1-10-6-8-12(9-7-10)15-13-5-3-4-11(2)14(13)18-16(17)19-15/h6-9,11H,3-5H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524362 (CHEMBL4467878) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(C)cc1 Show InChI InChI=1S/C16H19N3/c1-10-6-8-12(9-7-10)15-13-5-3-4-11(2)14(13)18-16(17)19-15/h6-9,11H,3-5H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524375 (CHEMBL4463811) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(Br)cc1 Show InChI InChI=1S/C15H16BrN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524375 (CHEMBL4463811) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(Br)cc1 Show InChI InChI=1S/C15H16BrN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524377 (CHEMBL4519923) Show SMILES CCCCc1cc(nc(N)n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C15H19N3O/c1-3-4-5-12-10-14(18-15(16)17-12)11-6-8-13(19-2)9-7-11/h6-10H,3-5H2,1-2H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524377 (CHEMBL4519923) Show SMILES CCCCc1cc(nc(N)n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C15H19N3O/c1-3-4-5-12-10-14(18-15(16)17-12)11-6-8-13(19-2)9-7-11/h6-10H,3-5H2,1-2H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524373 (CHEMBL4513478) Show SMILES CC1CCCc2c1nc(N)nc2-c1cccc(O)c1 Show InChI InChI=1S/C15H17N3O/c1-9-4-2-7-12-13(9)17-15(16)18-14(12)10-5-3-6-11(19)8-10/h3,5-6,8-9,19H,2,4,7H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524373 (CHEMBL4513478) Show SMILES CC1CCCc2c1nc(N)nc2-c1cccc(O)c1 Show InChI InChI=1S/C15H17N3O/c1-9-4-2-7-12-13(9)17-15(16)18-14(12)10-5-3-6-11(19)8-10/h3,5-6,8-9,19H,2,4,7H2,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524369 (CHEMBL4567405) Show SMILES COc1ccc(cc1)-c1nc(N)nc2CCC(C)Cc12 Show InChI InChI=1S/C16H19N3O/c1-10-3-8-14-13(9-10)15(19-16(17)18-14)11-4-6-12(20-2)7-5-11/h4-7,10H,3,8-9H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524369 (CHEMBL4567405) Show SMILES COc1ccc(cc1)-c1nc(N)nc2CCC(C)Cc12 Show InChI InChI=1S/C16H19N3O/c1-10-3-8-14-13(9-10)15(19-16(17)18-14)11-4-6-12(20-2)7-5-11/h4-7,10H,3,8-9H2,1-2H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524376 (CHEMBL4447843) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(cc1)C#N Show InChI InChI=1S/C16H16N4/c1-10-3-2-4-13-14(10)19-16(18)20-15(13)12-7-5-11(9-17)6-8-12/h5-8,10H,2-4H2,1H3,(H2,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524376 (CHEMBL4447843) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(cc1)C#N Show InChI InChI=1S/C16H16N4/c1-10-3-2-4-13-14(10)19-16(18)20-15(13)12-7-5-11(9-17)6-8-12/h5-8,10H,2-4H2,1H3,(H2,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241 BindingDB Entry DOI: 10.7270/Q23T9MN6
					More data for this Ligand-Target Pair

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