Compile Data Set for Download or QSAR

Found 342 hits with Last Name = 'fillery' and Initial = 'sm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50575300 (CHEMBL4851414) Show SMILES CN(C)C(=O)c1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575300 (CHEMBL4851414) Show SMILES CN(C)C(=O)c1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575298 (CHEMBL4859723) Show SMILES Cc1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575298 (CHEMBL4859723) Show SMILES Cc1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM291687 (N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...) Show SMILES Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI InChI=1S/C20H17FN6O/c1-12-13(3-2-7-22-12)16-10-24-20(27-11-25-26-19(16)27)23-9-15-14-6-8-28-18(14)5-4-17(15)21/h2-5,7,10-11H,6,8-9H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM291687 (N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...) Show SMILES Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI InChI=1S/C20H17FN6O/c1-12-13(3-2-7-22-12)16-10-24-20(27-11-25-26-19(16)27)23-9-15-14-6-8-28-18(14)5-4-17(15)21/h2-5,7,10-11H,6,8-9H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50575293 (CHEMBL4855253) Show SMILES Cn1nccc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584925 (CHEMBL5079885) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NC2CCN(CC(C)(C)F)CC2)c2nnc(C)n2n1 |r,THB:19:18:3.8.2:13.12.11| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50575293 (CHEMBL4855253) Show SMILES Cn1nccc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584925 (CHEMBL5079885) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NC2CCN(CC(C)(C)F)CC2)c2nnc(C)n2n1 |r,THB:19:18:3.8.2:13.12.11| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50575302 (CHEMBL4847216) Show SMILES CNC(=O)c1ccc(c(C)n1)-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575302 (CHEMBL4847216) Show SMILES CNC(=O)c1ccc(c(C)n1)-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575303 (CHEMBL4850478) Show SMILES CNC(=O)c1ncc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575303 (CHEMBL4850478) Show SMILES CNC(=O)c1ncc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575294 (CHEMBL4855124) Show SMILES Cc1ncc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575294 (CHEMBL4855124) Show SMILES Cc1ncc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575292 (CHEMBL4871456) Show SMILES Cc1nc(CO)ccc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584944 (CHEMBL5087319) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NCCCN2CCCC2)c2nnc(C)n2n1 |r,THB:19:18:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575292 (CHEMBL4871456) Show SMILES Cc1nc(CO)ccc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575291 (CHEMBL4850269) Show SMILES CN(C)C(=O)c1ccc(c(C)n1)-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575291 (CHEMBL4850269) Show SMILES CN(C)C(=O)c1ccc(c(C)n1)-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575296 (CHEMBL4870866) Show SMILES Cc1nn(C)cc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584944 (CHEMBL5087319) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NCCCN2CCCC2)c2nnc(C)n2n1 |r,THB:19:18:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575296 (CHEMBL4870866) Show SMILES Cc1nn(C)cc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575295 (CHEMBL4850017) Show SMILES Cc1nccn1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584945 (CHEMBL5093862) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NCCCN2CCC(F)(F)CC2)c2nnc(C)n2n1 |r,THB:19:18:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584945 (CHEMBL5093862) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NCCCN2CCC(F)(F)CC2)c2nnc(C)n2n1 |r,THB:19:18:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584946 (CHEMBL5090369) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NC2CCN(CC(C)(F)F)CC2)c2nnc(C)n2n1 |r,THB:19:18:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575289 (CHEMBL4858670) Show SMILES CN(C)Cc1ccc2C(=O)N(Cc2c1)c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575289 (CHEMBL4858670) Show SMILES CN(C)Cc1ccc2C(=O)N(Cc2c1)c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575274 (CHEMBL4856933) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2CC3(CC3)CC2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575286 (CHEMBL4862641) Show SMILES Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575274 (CHEMBL4856933) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2CC3(CC3)CC2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575295 (CHEMBL4850017) Show SMILES Cc1nccn1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575286 (CHEMBL4862641) Show SMILES Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584946 (CHEMBL5090369) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NC2CCN(CC(C)(F)F)CC2)c2nnc(C)n2n1 |r,THB:19:18:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575264 (CHEMBL4845735) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2Cc3ccccc3CC2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575301 (CHEMBL4866431) Show SMILES CNC(=O)c1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575301 (CHEMBL4866431) Show SMILES CNC(=O)c1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575264 (CHEMBL4845735) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2Cc3ccccc3CC2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50384248 (CHEMBL2030451) Show SMILES CS(=O)(=O)Cc1cc(nc(n1)-c1ccc(NC(=O)Nc2ccc(F)cc2)cc1)N1CCOCC1 Show InChI InChI=1S/C23H24FN5O4S/c1-34(31,32)15-20-14-21(29-10-12-33-13-11-29)28-22(25-20)16-2-6-18(7-3-16)26-23(30)27-19-8-4-17(24)5-9-19/h2-9,14H,10-13,15H2,1H3,(H2,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...				Bioorg Med Chem Lett 22: 4163-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.036 BindingDB Entry DOI: 10.7270/Q2N017KD
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575279 (CHEMBL4862266) Show SMILES CN(c1ncco1)c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575279 (CHEMBL4862266) Show SMILES CN(c1ncco1)c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50584941 (CHEMBL5077167) Show SMILES [H][C@]12Cc3ccccc3[C@]([H])(CNC1=O)N2C(=O)c1cc(NC2CCN(C)CC2)c2nnc(C)n2n1 |r,THB:16:15:11.12.13:3.8.2| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8
					More data for this Ligand-Target Pair				3D Structure (crystal)
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50157003 (CHEMBL369352 | N-Cyclopropyl-N-[1-(3,3-diphenyl-pr...) Show SMILES NS(=O)(=O)c1ccc(CC(=O)N(C2CC2)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C31H37N3O3S/c32-38(36,37)29-15-11-24(12-16-29)23-31(35)34(27-13-14-27)28-17-20-33(21-18-28)22-19-30(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-12,15-16,27-28,30H,13-14,17-23H2,(H2,32,36,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...				Bioorg Med Chem Lett 15: 25-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.044 BindingDB Entry DOI: 10.7270/Q2833RJJ
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50157002 (1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...) Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NCc1cccc(C)c1 Show InChI InChI=1S/C31H39N3O/c1-3-34(31(35)32-24-26-12-10-11-25(2)23-26)29-17-20-33(21-18-29)22-19-30(27-13-6-4-7-14-27)28-15-8-5-9-16-28/h4-16,23,29-30H,3,17-22,24H2,1-2H3,(H,32,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...				Bioorg Med Chem Lett 15: 25-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.044 BindingDB Entry DOI: 10.7270/Q2833RJJ
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575263 (CHEMBL4846342) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2Cc3ccccc3C2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575267 (CHEMBL4869385) Show SMILES CN(C)Cc1ccc2C(=O)N(Cc2c1)c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575267 (CHEMBL4869385) Show SMILES CN(C)Cc1ccc2C(=O)N(Cc2c1)c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575263 (CHEMBL4846342) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2Cc3ccccc3C2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair

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