Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
(S)-6-hydroxynicotine oxidase (Arthrobacter nicotinovorans) | BDBM181053 ((S)-6-hydroxynicotine) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | 8.0 | n/a |
University of Texas Health Science Center at San Antonio | Assay Description Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 °C using an ox... | Biochemistry 55: 697-703 (2016) Article DOI: 10.1021/acs.biochem.5b01325 BindingDB Entry DOI: 10.7270/Q2HD7TFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
(S)-6-hydroxynicotine oxidase (Arthrobacter nicotinovorans) | BDBM181054 ((S)-6-hydroxynornicotine) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | 8.0 | n/a |
University of Texas Health Science Center at San Antonio | Assay Description Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 °C using an ox... | Biochemistry 55: 697-703 (2016) Article DOI: 10.1021/acs.biochem.5b01325 BindingDB Entry DOI: 10.7270/Q2HD7TFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
(S)-6-hydroxynicotine oxidase (Arthrobacter nicotinovorans) | BDBM181055 ((S)-nornicotine) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.60E+6 | n/a | n/a | n/a | 8.0 | n/a |
University of Texas Health Science Center at San Antonio | Assay Description Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 °C using an ox... | Biochemistry 55: 697-703 (2016) Article DOI: 10.1021/acs.biochem.5b01325 BindingDB Entry DOI: 10.7270/Q2HD7TFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
(S)-6-hydroxynicotine oxidase [Y311F] (Arthrobacter nicotinovorans) | BDBM217378 ((S)-6-hydroxynicotine | 5-[(2S)-1-methylpyrrolidin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 9.60E+4 | n/a | n/a | n/a | 8.0 | 298.15 |
University of Texas Health Science Center | Assay Description Initial rates of amine oxidation were measured by monitoring oxygen consumption using an oxygen electrode (model 5300A, Yellow Springs Instruments, Y... | Biochemistry 56: 869-875 (2017) Article DOI: 10.1021/acs.biochem.6b01160 BindingDB Entry DOI: 10.7270/Q2BR8R0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
(S)-6-hydroxynicotine oxidase [N166A] (Arthrobacter nicotinovorans) | BDBM217378 ((S)-6-hydroxynicotine | 5-[(2S)-1-methylpyrrolidin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.10E+5 | n/a | n/a | n/a | 8.0 | 298.15 |
University of Texas Health Science Center | Assay Description Initial rates of amine oxidation were measured by monitoring oxygen consumption using an oxygen electrode (model 5300A, Yellow Springs Instruments, Y... | Biochemistry 56: 869-875 (2017) Article DOI: 10.1021/acs.biochem.6b01160 BindingDB Entry DOI: 10.7270/Q2BR8R0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
(S)-6-hydroxynicotine oxidase [K287M] (Arthrobacter nicotinovorans) | BDBM217378 ((S)-6-hydroxynicotine | 5-[(2S)-1-methylpyrrolidin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 6.10E+4 | n/a | n/a | n/a | 8.0 | 298.15 |
University of Texas Health Science Center | Assay Description Initial rates of amine oxidation were measured by monitoring oxygen consumption using an oxygen electrode (model 5300A, Yellow Springs Instruments, Y... | Biochemistry 56: 869-875 (2017) Article DOI: 10.1021/acs.biochem.6b01160 BindingDB Entry DOI: 10.7270/Q2BR8R0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
(S)-6-hydroxynicotine oxidase (Arthrobacter nicotinovorans) | BDBM181056 ((S)-4-(1-methylpyrrolidine-2-yl)phenol) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | 8.0 | n/a |
University of Texas Health Science Center at San Antonio | Assay Description Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 °C using an ox... | Biochemistry 55: 697-703 (2016) Article DOI: 10.1021/acs.biochem.5b01325 BindingDB Entry DOI: 10.7270/Q2HD7TFT | |||||||||||
More data for this Ligand-Target Pair |